LOCUS       NM_025680               2731 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus catenin, beta like 1 (Ctnnbl1), mRNA.
ACCESSION   NM_025680
VERSION     NM_025680.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Chanarat,S. and Strasser,K.
  TITLE     Splicing and beyond: the many faces of the Prp19 complex
  JOURNAL   Biochim Biophys Acta 1833 (10), 2126-2134 (2013)
   PUBMED   23742842
  REMARK    Review article
REFERENCE   2  (bases 1 to 2731)
  AUTHORS   Chandra,A., van Maldegem,F., Andrews,S., Neuberger,M.S. and Rada,C.
  TITLE     Deficiency in spliceosome-associated factor CTNNBL1 does not affect
            ongoing cell cycling but delays exit from quiescence and results in
            embryonic lethality in mice
  JOURNAL   Cell Cycle 12 (5), 732-742 (2013)
   PUBMED   23343763
  REMARK    GeneRIF: CTNNBL1 plays no essential role in cycling cells but does
            fulfill an evolutionarily conserved function in helping cells to
            undergo efficient exit from quiescence following activation.
REFERENCE   3  (bases 1 to 2731)
  AUTHORS   Ganesh,K., Adam,S., Taylor,B., Simpson,P., Rada,C. and Neuberger,M.
  TITLE     CTNNBL1 is a novel nuclear localization sequence-binding protein
            that recognizes RNA-splicing factors CDC5L and Prp31
  JOURNAL   J Biol Chem 286 (19), 17091-17102 (2011)
   PUBMED   21385873
  REMARK    GeneRIF: CTNNBL1 is a novel nuclear localization sequence-binding
            protein that recognizes RNA-splicing factors CDC5L and Prp31
REFERENCE   4  (bases 1 to 2731)
  AUTHORS   Han,L., Masani,S. and Yu,K.
  TITLE     Cutting edge: CTNNBL1 is dispensable for Ig class switch
            recombination
  JOURNAL   J Immunol 185 (3), 1379-1381 (2010)
   PUBMED   20585033
  REMARK    GeneRIF: Normal levels of immunoglobulin class switch recombination
            (CSR) factors are found in DTNNBL1-deficient cells, indicating that
            CTNNBL1 is dispensable for CSR.
REFERENCE   5  (bases 1 to 2731)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 2731)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   7  (bases 1 to 2731)
  AUTHORS   Jabbour,L., Welter,J.F., Kollar,J. and Hering,T.M.
  TITLE     Sequence, gene structure, and expression pattern of CTNNBL1, a
            minor-class intron-containing gene--evidence for a role in
            apoptosis
  JOURNAL   Genomics 81 (3), 292-303 (2003)
   PUBMED   12659813
REFERENCE   8  (bases 1 to 2731)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 2731)
  AUTHORS   Korinek,V., Barker,N., Willert,K., Molenaar,M., Roose,J.,
            Wagenaar,G., Markman,M., Lamers,W., Destree,O. and Clevers,H.
  TITLE     Two members of the Tcf family implicated in Wnt/beta-catenin
            signaling during embryogenesis in the mouse
  JOURNAL   Mol Cell Biol 18 (3), 1248-1256 (1998)
   PUBMED   9488439
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL669961.8, AK145598.1 and AL663092.15.
            
            On Jul 21, 2009 this sequence version replaced NM_025680.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK145719.1, AK145598.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                AL669961.8         152164-152220
            58-2409             AK145598.1         2-2353
            2410-2731           AL663092.15        105408-105729
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 78.4 cM"
     gene            1..2731
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /note="catenin, beta like 1"
                     /db_xref="GeneID:66642"
                     /db_xref="MGI:MGI:1913892"
     exon            1..159
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..1821
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /note="nuclear protein NAP; nuclear-associated protein"
                     /codon_start=1
                     /product="beta-catenin-like protein 1"
                     /protein_id="NP_079956.3"
                     /db_xref="CCDS:CCDS16982.1"
                     /db_xref="GeneID:66642"
                     /db_xref="MGI:MGI:1913892"
                     /translation="MDVGELLSYQPNRGTKRPRDDEEEELKTRRKQTGPRERGRYREE
                     EATAAEDTADDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFEKRSYKNQELRIK
                     FPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELSAVQSLLGLLGHDNTDVSIA
                     VVDLLQELTDIDTLHESEEGAEVLIDALVDGQVAALLVQNLERLDESVREEADGVHNT
                     LAIVENMAEFRPEMCTEAAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDEN
                     RELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDALCSCLMLSSNRERFLKGE
                     GLQLMNLMLREKKVSRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFMKSPRK
                     IKKVGTTEKEHEEHVCSILASLLRNLRGQQRTRLLNKFTENDSEKVDRLMELHFKYLS
                     AMQVADKKIEGEKHDIVRRGEIIDNDMEDEFYLRRLDAGLFILQHICYIMAEICNANV
                     PQIRQRVHQILNMRGSSIKIVRHIIKEYAENIGDGRSPEFRETEQKRILALLENF"
     exon            160..348
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            349..455
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            456..595
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            596..693
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            694..787
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            788..879
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            880..952
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1011
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1160
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1342
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..1440
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1521
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1659
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1732
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1733..2731
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1901..1906
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /note="hexamer: ATTAAA"
     polyA_site      1919
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /note="major polyA site"
     regulatory      2393..2398
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
                     /note="hexamer: AATAAA"
     polyA_site      2437
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
     polyA_site      2455
                     /gene="Ctnnbl1"
                     /gene_synonym="5730471K09Rik; NAP; NYD-SP19; P14L"
ORIGIN      
        1 tcttttactc tattggttct ggggcctggc gctttacggc agtgtgtcag gaaaagcctc
       61 tgagcggccc gtggttcggg agttgagtgg aggcaaccag ggtaccctgt gctgattggg
      121 tccggaacca tggacgtggg cgaactttta agctaccagc ccaacagggg cacaaaacga
      181 ccccgggatg atgaggaaga agaactgaag acacgccgca agcaaactgg tcctcgagaa
      241 cgcggccgct atcgcgaaga ggaggccacg gcagccgaag acacagctga tgacaagaaa
      301 aggctgctgc agattattga cagggatggc gaggaagaag aggaggagga ggagccgctg
      361 gatgaaagct cagtgaagaa gatgattctc acatttgaga agcgatccta caaaaaccag
      421 gagctgcgga tcaagtttcc agacaatccg gagaagttca tggaatccga gctggacctc
      481 aatgacatca ttcaggagat gcacgtggtg gccaccatgc ctgacctgta ccaccttctc
      541 gtggagctga gtgccgtgca gtcacttctc ggcttgctgg gacatgataa tacagatgtg
      601 tccatagctg tggtcgatct cctccaggag ctgacagaca tagacaccct ccacgagagt
      661 gaagaaggag cagaagttct catcgacgcc ctggtggacg ggcaggtggc cgcattgttg
      721 gtgcagaatc tggagcgcct ggatgagtct gtgagggagg aggctgatgg cgtccacaac
      781 accctagcta ttgtggagaa tatggccgag ttccgtccgg agatgtgcac agaggctgcc
      841 cagcagggac tcctgcagtg gctgttgaag aggctgaagg ccaagatgcc cttcgatgcc
      901 aacaagctgt actgtagtga agtgctggcc atcctcctcc aggacaatga cgaaaacagg
      961 gaattgctgg gagagctgga tggcattgac gtgcttcttc agcagttatc cgtatttaaa
     1021 agacacaacc ccagcaccgc tgaggagcag gaaatgatgg agaacctgtt cgatgcgctc
     1081 tgttcctgct taatgctcag ctccaatcga gagcgcttcc tgaagggcga ggggctgcag
     1141 ctcatgaacc tcatgctcag ggagaagaag gtctcccgga gcagcgccct gaaggtgctg
     1201 gaccatgcca tgattgggcc tgaaggcaca gacaactgcc acaagtttgt tgacattctt
     1261 ggcttacgga ccatctttcc actcttcatg aagtctcctc ggaaaatcaa gaaggtggga
     1321 accacagaga aggagcatga agagcatgtc tgttcgatcc tggcttccct cctgcgcaac
     1381 ctgagagggc agcagcggac ccggcttctg aataaattta cggagaacga cagtgagaag
     1441 gttgacagac taatggagct gcattttaaa tatctcagcg caatgcaggt ggccgacaag
     1501 aagattgaag gggagaaaca tgacatagtg cggcgtgggg agatcataga caatgacatg
     1561 gaggacgagt tctacctgcg gcgcctggat gccgggctct tcatcctaca gcacatctgt
     1621 tacatcatgg cggagatctg caatgccaat gtcccccaga ttcgccagcg ggttcaccag
     1681 atcctgaaca tgcgtggcag ctccatcaag atcgtcaggc acatcatcaa ggagtacgca
     1741 gagaacattg gagatggccg gagccctgag ttccgggaga ccgagcagaa gcgcatcctg
     1801 gccttgttgg agaacttcta gaatgctagg gagagcgtga cggccaccga cccctggctc
     1861 cctcctggaa accattttta cagttgtatg gcttgaacaa attaaagcta gttttggtat
     1921 cctggggctg acattgtatg tgtaagcttc ccgccagccc tgtcccgctc ctccccagtg
     1981 agcacaggca cacctgggga aggccagaga agccagtggt gacaggagac acctggtgtg
     2041 ggcagcaccc gtttgtgcac agcagtctga acagggctct gggactgccg ggcacagggg
     2101 attacctgcc actgcagtcc cagcacatca ctacaccccc acccccaccc acagccctgt
     2161 gcttctgtct tcaaatgcct ggagtaggcg agtctgcaga caccacccag agctgtggct
     2221 gctgggagct caggagccag ggaatgcagc caggaacaga ggggcatggt tttctcacag
     2281 ggtggtggaa acgctctgtg gttggtcatg gatgtgagca cacttcattg tgagcacgct
     2341 gataccacgg agttgtacat tctcagagga caaatcaaat gatgtggttt ctaataaagc
     2401 tgttgaggga agggggctgc taagccgtcg accttcagtc tggactgctt ctctagtctt
     2461 gcgatgtgct tcccacagaa ttgtcctagc tcttgtggga gtttggacgt taccatttgc
     2521 aaccttaaga ttttattctt ggatgagtgt ggtggtacac gcctttaatc ccagcacttg
     2581 ggaggcaaag gcagacagat ctttgagttc aaagctaaca tggtctatag agcaaggtcc
     2641 aggacagcca ggactacaca gagaaaccct gtctcaaaaa acccaaatta ataataatat
     2701 taataataaa atagtaatag tgataatctg t
//
