LOCUS       NM_023465               2686 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus catenin beta interacting protein 1 (Ctnnbip1),
            transcript variant 1, mRNA.
ACCESSION   NM_023465
VERSION     NM_023465.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2686)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2686)
  AUTHORS   Tang,C., Chen,Y., Jin,H., Lei,L., Xiang,Y., Cheng,Y. and Huang,B.
  TITLE     miR-342-5p targets CTNNBIP1 to promote enterovirus 71 replication
  JOURNAL   Microb Pathog 182, 106259 (2023)
   PUBMED   37479047
  REMARK    GeneRIF: miR-342-5p targets CTNNBIP1 to promote enterovirus 71
            replication.
REFERENCE   3  (bases 1 to 2686)
  AUTHORS   Song,Z., Liu,N., He,Y., Chen,J., Li,J., Wang,F. and Wu,Z.
  TITLE     Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in
            Obese Mice
  JOURNAL   Inflammation 46 (1), 404-417 (2023)
   PUBMED   36181623
  REMARK    GeneRIF: Knockout of ICAT in Adipose Tissue Alleviates
            Fibro-inflammation in Obese Mice.
REFERENCE   4  (bases 1 to 2686)
  AUTHORS   Peng,Y., Li,H., Li,X., Yu,S., Xiang,H., Peng,J. and Jiang,S.
  TITLE     MicroRNA-215 impairs adipocyte differentiation and co-represses
            FNDC3B and CTNNBIP1
  JOURNAL   Int J Biochem Cell Biol 79, 104-112 (2016)
   PUBMED   27521659
  REMARK    GeneRIF: miR-215-5p is a negative regulator of adipocyte
            differentiation through post-transcriptional regulation of FNDC3B
            and CTNNBIP1 during early adipogenesis
REFERENCE   5  (bases 1 to 2686)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   6  (bases 1 to 2686)
  AUTHORS   Kanamori,M., Sandy,P., Marzinotto,S., Benetti,R., Kai,C.,
            Hayashizaki,Y., Schneider,C. and Suzuki,H.
  TITLE     The PDZ protein tax-interacting protein-1 inhibits beta-catenin
            transcriptional activity and growth of colorectal cancer cells
  JOURNAL   J Biol Chem 278 (40), 38758-38764 (2003)
   PUBMED   12874278
REFERENCE   7  (bases 1 to 2686)
  AUTHORS   Graham,T.A., Clements,W.K., Kimelman,D. and Xu,W.
  TITLE     The crystal structure of the beta-catenin/ICAT complex reveals the
            inhibitory mechanism of ICAT
  JOURNAL   Mol Cell 10 (3), 563-571 (2002)
   PUBMED   12408824
REFERENCE   8  (bases 1 to 2686)
  AUTHORS   Sekiya,T., Nakamura,T., Kazuki,Y., Oshimura,M., Kohu,K., Tago,K.,
            Ohwada,S. and Akiyama,T.
  TITLE     Overexpression of Icat induces G(2) arrest and cell death in tumor
            cell mutants for adenomatous polyposis coli, beta-catenin, or Axin
  JOURNAL   Cancer Res 62 (11), 3322-3326 (2002)
   PUBMED   12036951
  REMARK    GeneRIF: Overexpression of Icat induces G(2) arrest and cell death
            in tumor cell mutants for adenomatous polyposis coli, beta-catenin,
            or Axin.
REFERENCE   9  (bases 1 to 2686)
  AUTHORS   Tutter,A.V., Fryer,C.J. and Jones,K.A.
  TITLE     Chromatin-specific regulation of LEF-1-beta-catenin transcription
            activation and inhibition in vitro
  JOURNAL   Genes Dev 15 (24), 3342-3354 (2001)
   PUBMED   11751639
REFERENCE   10 (bases 1 to 2686)
  AUTHORS   Tago,K., Nakamura,T., Nishita,M., Hyodo,J., Nagai,S., Murata,Y.,
            Adachi,S., Ohwada,S., Morishita,Y., Shibuya,H. and Akiyama,T.
  TITLE     Inhibition of Wnt signaling by ICAT, a novel
            beta-catenin-interacting protein
  JOURNAL   Genes Dev 14 (14), 1741-1749 (2000)
   PUBMED   10898789
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK036181.1 and BQ031304.1.
            
            On Nov 20, 2008 this sequence version replaced NM_023465.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036181.1, AB021261.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-523               AK036181.1         2-524
            524-1030            AK036181.1         526-1032
            1031-2423           AK036181.1         1034-2426
            2424-2686           BQ031304.1         1-263               c
FEATURES             Location/Qualifiers
     source          1..2686
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 79.66 cM"
     gene            1..2686
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /note="catenin beta interacting protein 1"
                     /db_xref="GeneID:67087"
                     /db_xref="MGI:MGI:1915756"
     exon            1..139
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /inference="alignment:Splign:2.1.0"
     exon            140..224
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /inference="alignment:Splign:2.1.0"
     exon            225..345
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /inference="alignment:Splign:2.1.0"
     exon            346..436
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /inference="alignment:Splign:2.1.0"
     exon            437..2669
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /inference="alignment:Splign:2.1.0"
     regulatory      706..711
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /note="hexamer: AAGAAA"
     polyA_site      743
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /note="major polyA site"
     regulatory      1029..1034
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /note="hexamer: AAGAAA"
     polyA_site      1046
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /note="major polyA site"
     regulatory      2649..2654
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /note="hexamer: AATAAA"
     polyA_site      2668
                     /gene="Ctnnbip1"
                     /gene_synonym="1110008O09Rik; 2310001I19Rik; Catnbip1;
                     Icat"
                     /note="major polyA site"
ORIGIN      
        1 acggagaggc ggaggctgag gcggccgctc ctggtgctgc tgccgccgcc gcggctgctt
       61 ctccggctga gcgcgccccg gaacaggccg ccgcgctccg gacccgcagc ccccggcgcc
      121 gcgcgttcgg gcggcccagg gcggcacctt gctatttctt ctcaggcgcg gtcctcccct
      181 tagagttgag catctgtttg cctgaagtga atttccagaa gcaggtgtcc ccagaactgg
      241 gccaggggga tgaaccgcga gggagcaccc gggaagagtc cggaggagat gtacattcaa
      301 cagaaggtcc gcgtgctgct catgctgagg aagatggggt caaacctgac cgccagtgag
      361 gaggaatttc tgcgcaccta tgctggggtc gtcagcagcc agctcagcca gctgccacag
      421 cactccatcg accagggtgc agaggacgtg gtgatggcgt tttccagatc ggagacggaa
      481 gaccggaggc agtagctgga agcccctcgg aactccctgg aagctgcaga tggccaagag
      541 atctgtgtgg ctcctctgcc ggttgagtgg tagcaaacca ccgtcttctt accctttgca
      601 ccccttaccc catccgaccc tccccaccca gccgccactc agcagggctg gcatcaaggt
      661 ggtttgtgat tggcttaaag ggatggactt gagattggct gcaggaagaa acctttttat
      721 ttttaaatct tgaccaacgg aaacctttta tttttatttc tgactcttta tttttttaaa
      781 catttgcgcc tcggtatctg gcttccccgg aagctctccg agctctggtg ctttatttag
      841 gtcattttta ggaatgtgaa gaggcctgat tggttgctta aactggaaaa gggttatgat
      901 tggctggcta gtgggacgtg gtcttttctt tgattggctg taggtgttct gttcacatca
      961 ccgacttcct ctgttctgaa agcagaaaac agggtttggg atattgttat atttgacttg
     1021 aaaaaaaaaa gaaagaaaga aatgaagtga gctttgcaat atttattaca caaagagctg
     1081 gctgctgcct tcacgtagtg ggtttgtgtt tggatttgat tggcagtaag atgcgggttt
     1141 ggtttcccat tggctcaccc ctgactcccg ttgctatggt ctttcttcca ctctgctggt
     1201 tacatgaggc ctgagggtac acctggagaa tgcacgtgct ttaatgacca cacctgcctc
     1261 caccagcgaa gggaccccag ggacgcgagc gcgagcgggg tccacagctg gagaacaggc
     1321 ccccaagggg ctttgtgttc tcctgagcca gcagcccaga gctcaggggt gaccgggagg
     1381 caggattgat gtactcagtt ctaagagctg gcagccagcc agtttcctgg agcgaatgga
     1441 ttgtgcagag ctcttcaggc ctttctggcc agcccatgct aagtacagga gtgttgaccg
     1501 gcagctccag cctctctgct gccccctgtg tctcacttcc ccaggtcttg gcatccccag
     1561 atcctgaagg ttatgagggg tctttactgg agccttgaac ccaagcagat accccagttt
     1621 cacttctaga accccagagg tttcaaactt ggctccaagc acaacctagc caggcttccc
     1681 agggtccatt gccagtggct gtagttcccg gatagcagat gtgttctacc tgagcccagg
     1741 cccccattac accgtgtatc accctgtgtg tcagcataga agggggagta gcatggctta
     1801 tttattagga agcacccact tggaagacca gctagacttt cacacagtag gccccacagg
     1861 ctactcagat ccagcccaag ggtcacattt tagagcagcg actgagaaga aagatatggg
     1921 tggtcgtccc atgcccacca tgccttccct gggagtgaga gaaacggtga cggccctttc
     1981 tggtcctggg caccatgatc cggaaaacac tggagcatct tttcccttct tggggcttcg
     2041 gcctcccgtg tggcagggag tgtgcaggat gccagtgcca gcaggtcttg agttcaagcc
     2101 ctggggcacc tccctgttgg tggacggttc aagcttccca gacatgtccc aggaggagaa
     2161 tgtgaacatc tggtccctca gcacatcggc cctgttagct gacagtaaca tgctcgcttt
     2221 ggccattgag ctccagggag caaggacagt ggagaatcag ctccgccaac cccagcctga
     2281 ccagcaagag cctgagagga gagcgtcatt gctggggagg agcagcgtgt gtgagcaggc
     2341 acggtatgag ctcacactga ctgacagacg cgtgcttgtt ctgctggcgc agtgtggcct
     2401 ggagatgtgg ctgggcccgt gggcagagat ggggtcattc agtcttcctc ccctgtgaga
     2461 ttgtatctaa agtccggtgt tgccagcttc agttggttcc tgtgactgcc tcgaggccaa
     2521 gccctggtga tggtgtgtgc tctgtcttag cagtggttct cggctcagcc tctgagggaa
     2581 aaagatgcaa gtatcgatgt ggcttcttat tctaactgaa agtctatcta atggagaaaa
     2641 aaaataacaa taaagatttt tcacagctta aaaaaaaaaa aaaaaa
//
