LOCUS       NM_001109764            4148 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus catenin alpha 2 (Ctnna2), transcript variant 3, mRNA.
ACCESSION   NM_001109764
VERSION     NM_001109764.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4148)
  AUTHORS   Martin,J.B., Herman,K., Houssin,N.S., Rich,W., Reilly,M.A. and
            Plageman,T.F. Jr.
  TITLE     Arvcf Dependent Adherens Junction Stability is Required to Prevent
            Age-Related Cortical Cataracts
  JOURNAL   Front Cell Dev Biol 10, 840129 (2022)
   PUBMED   35874813
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4148)
  AUTHORS   Sun,J., Ha,N., Liu,Z., Bian,Q. and Wang,X.
  TITLE     A Neural Crest-specific Overexpression Mouse Model Reveals the
            Transcriptional Regulatory Effects of Dlx2 During Maxillary Process
            Development
  JOURNAL   Front Physiol 13, 855959 (2022)
   PUBMED   35514355
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4148)
  AUTHORS   Mohammad,R.Z., Murakawa,H., Svadlenka,K. and Togashi,H.
  TITLE     A numerical algorithm for modeling cellular rearrangements in
            tissue morphogenesis
  JOURNAL   Commun Biol 5 (1), 239 (2022)
   PUBMED   35304570
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4148)
  AUTHORS   Duethorn,B., Groll,F., Rieger,B., Drexler,H.C.A., Brinkmann,H.,
            Kremer,L., Stehling,M., Borowski,M.T., Mildner,K., Zeuschner,D.,
            Zernicka-Goetz,M., Stemmler,M.P., Busch,K.B., Vaquerizas,J.M. and
            Bedzhov,I.
  TITLE     Lima1 mediates the pluripotency control of membrane dynamics and
            cellular metabolism
  JOURNAL   Nat Commun 13 (1), 610 (2022)
   PUBMED   35105859
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4148)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4148)
  AUTHORS   Qiu,M., Bulfone,A., Martinez,S., Meneses,J.J., Shimamura,K.,
            Pedersen,R.A. and Rubenstein,J.L.
  TITLE     Null mutation of Dlx-2 results in abnormal morphogenesis of
            proximal first and second branchial arch derivatives and abnormal
            differentiation in the forebrain
  JOURNAL   Genes Dev 9 (20), 2523-2538 (1995)
   PUBMED   7590232
REFERENCE   7  (bases 1 to 4148)
  AUTHORS   Guenet,J.L., Simon-Chazottes,D., Ringwald,M. and Kemler,R.
  TITLE     The genes coding for alpha and beta catenin (Catna1 and Catnb) and
            plakoglobin (Jup) map to mouse chromosomes 18, 9, and 11,
            respectively
  JOURNAL   Mamm Genome 6 (5), 363-366 (1995)
   PUBMED   7626889
REFERENCE   8  (bases 1 to 4148)
  AUTHORS   Hirano,S., Kimoto,N., Shimoyama,Y., Hirohashi,S. and Takeichi,M.
  TITLE     Identification of a neural alpha-catenin as a key regulator of
            cadherin function and multicellular organization
  JOURNAL   Cell 70 (2), 293-301 (1992)
   PUBMED   1638632
REFERENCE   9  (bases 1 to 4148)
  AUTHORS   Ozawa,M., Ringwald,M. and Kemler,R.
  TITLE     Uvomorulin-catenin complex formation is regulated by a specific
            domain in the cytoplasmic region of the cell adhesion molecule
  JOURNAL   Proc Natl Acad Sci U S A 87 (11), 4246-4250 (1990)
   PUBMED   2349235
REFERENCE   10 (bases 1 to 4148)
  AUTHORS   Ozawa,M., Baribault,H. and Kemler,R.
  TITLE     The cytoplasmic domain of the cell adhesion molecule uvomorulin
            associates with three independent proteins structurally related in
            different species
  JOURNAL   EMBO J 8 (6), 1711-1717 (1989)
   PUBMED   2788574
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CD578966.1, BC079648.1 and BC051995.1.
            
            Transcript Variant: This variant (3) represents the longest
            transcript and encodes the longer isoform (2). Variants 2 and 3
            both encode isoform 2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079648.1, SRR1660813.241653.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-248               CD578966.1         1-248
            249-2028            BC079648.1         166-1945
            2029-4148           BC051995.1         1808-3927
FEATURES             Location/Qualifiers
     source          1..4148
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 33.54 cM"
     gene            1..4148
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /note="catenin alpha 2"
                     /db_xref="GeneID:12386"
                     /db_xref="MGI:MGI:88275"
     exon            1..248
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            249..350
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            351..457
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            458..653
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            654..820
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            821..940
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1207
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1411
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            1412..1492
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1645
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1738
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            1739..1895
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            1896..2096
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            2097..2248
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..2362
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            2363..2544
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            2545..2650
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            2651..2785
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            2786..2929
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     exon            2930..4130
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4110..4115
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /note="hexamer: AATAAA"
     polyA_site      4130
                     /gene="Ctnna2"
                     /gene_synonym="Catna; Catna2; cdf; chp"
                     /note="major polyA site"
ORIGIN      
        1 cgggccgctg ccgctcgctt gggcaggacg cggggcgggc ggggggaggg gggagcggct
       61 ttgctggcag ccctgagtga ggcggagacc cgggcggagc gggcggcacc gcacctcggc
      121 cagaagcagc tgcagcagct gccctagtcc ccaccgccgc ctctccagca gcttctgtca
      181 ttccgcgcca gctgctgcag acagaggacg aggaggagga ggcgagaaac tcccaccgac
      241 ccacagagag gccgtgagac cagttgttag cattcaagtc aggaggctca tagctccagt
      301 gccaggaggt tttactatga cagatattca ctcaagctac acatacacag ggagcatgac
      361 ttcggcaact tcacctatta ttttaaaatg ggatcccaaa agtttggaaa tccggacact
      421 cacagtggaa agactattgg agccacttgt gacacaggtg acaacacttg tcaacacaag
      481 caacaaaggt ccgtctggta aaaagaaagg gaggtcaaag aaagcccatg tgctggcagc
      541 atctgtagaa caagctactc agaacttcct ggaaaagggt gaacagatcg ctaaggagag
      601 ccaagacctc aaagaagagt tagtggctgc tgtagaggat gtgcggaagc aaggtgagac
      661 aatgcggatt gcctcctcag agtttgcaga tgacccttgc tcttctgtca agcgtggcac
      721 catggtgcgt gcagcacggg ctctgctatc ggctgtgaca cgcttgctca tcctggccga
      781 catggcagat gtcatgaggc ttttatcgca tctgaaaatt gtcgaggagg ccttggaagc
      841 agtcaaaaat gccacaaatg aacaagacct tgcaaaccga tttaaagagt ttgggaaaga
      901 gatggtgaaa ctgaactatg tagcagcaag acggcagcag gagctcaagg accctcactg
      961 tagggatgag atggctgcag cccgtggagc cctgaagaag aatgccacca tgctgtacac
     1021 agcctcccaa gccttcctcc ggcatccaga tgttgctgct acaagagcca accgagatta
     1081 tgtatttaaa caagtccaag aggccatagc tggcatctcc agtgctgctc aggccacctc
     1141 ccccaccgat gaagccaaag gccacacagg catcggcgag ctggctgcag ccctgaatga
     1201 gtttgataat aagatcatcc tggaccccat gacattcagc gaggccaggt tccgaccatc
     1261 cctggaggag agactggaga gcatcatcag tggggctgct ctcatggcag attcctcctg
     1321 cacacgtgat gaccgccgtg agcgtattgt ggccgagtgc aatgcagttc gacaggcact
     1381 ccaggacctg ctaagcgagt acatgaataa cactggaagg aaagagaaag gagaccctct
     1441 caacattgcg attgacaaga tgaccaagaa aacaagagat ctgaggagac agcttcggaa
     1501 agctgtgatg gatcacatct cagattcttt cttggaaacc aatgtcccct tgctggttct
     1561 cattgaggct gcgaagagcg ggaatgagaa ggaggtgaag gaatacgccc aagttttccg
     1621 tgaacatgcc aacaagctgg tggaggttgc caatttggct tgttccatct ccaacaatga
     1681 ggaaggggtg aaattagtca gaatggcagc cacccagatt gacagcctgt gtccccaagt
     1741 cattaatgct gccctcacac tggctgctcg gccacagagt aaagttgctc aggacaacat
     1801 ggatgtcttc aaagaccagt gggaaaagca agtccgtgtg ctcactgagg cagtggatga
     1861 catcacctct gtggatgact tcctctctgt ctcagaaaac catatcttgg aggatgtgaa
     1921 caaatgtgtg attgccctgc aagagggaga tgtggacaca ctggatcgca cagctggggc
     1981 catacggggc cgggcagccc gggtcattca catcatcaat gcagagatgg agaactatga
     2041 agctggggtc tatacagaga aagtgctgga agccacaaaa ttgctttcag aaacagtgat
     2101 gccacgcttt gctgaacaag ttgaggtggc catcgaagcc ctgagcgcca atgtccctca
     2161 gccattcgag gagaacgagt tcatcgatgc ctcgcgcctg gtgtatgacg gtgttcggga
     2221 catcagaaag gctgtgctga tgatcaggac tccagaagag ctagaagatg attccgactt
     2281 tgagcaagag gattatgatg tgcggagtcg gacaagtgtt cagacagagg acgaccagct
     2341 cattgctgga cagagtgcac gggccatcat ggcgcaacta ccacaggagg agaaagcaaa
     2401 aatagctgaa caggtggaga ttttccacca agaaaaaagc aagctggatg ctgaagtggc
     2461 caagtgggat gacagcggca atgacatcat tgtgctggcc aagcagatgt gtatgatcat
     2521 gatggagatg acagacttca caagaggcaa aggcccactg aaaaatacat ctgatgtcat
     2581 taatgctgcc aagaagattg cagaagcagg ctctcgaatg gacaaattag cgcgcgctgt
     2641 ggctgatcag tgtcctgatt cagcatgtaa gcaggattta ttagcctacc ttcagcggat
     2701 tgctttgtac tgccatcagc ttaacatctg cagcaaagtg aaggccgagg ttcagaacct
     2761 aggaggagag ctcattgtgt cagggacagg agttcagagc actttcacta ccttttatga
     2821 ggtagattgt gatgtcatag atgggggcag ggctagtcaa ctttctaccc acctcccaac
     2881 ctgtgctgag ggagctccaa tcgggagtgg aagcagtgac tcctccatgc tggacagtgc
     2941 tacatcactc atccaggcag ccaaaaacct gatgaatgct gttgtcctca cggtgaaagc
     3001 gtcttatgta gcctcaacta aataccagaa ggtctatgga acagcagctg tcaactctcc
     3061 agttgtgtct tggaagatga aggctcctga aaagaagccc cttgtgaaga gagaaaagcc
     3121 tgaagaattc cagacaagag ttagacgggg gtctcaaaag aaacacattt cacctgtgca
     3181 ggctttaagt gaattcaagg caatggattc cttctaggac aataggctac aaacaagaaa
     3241 gctttttctt tccctcctcc ccctttcttt ttcattttga ttccattttt tgtaagcata
     3301 cctgctgact tgtctgcctc tggcatgggg aaattaagag aacagtgtct gtttgcatgt
     3361 tagacgagat gagatcaatg ctgctggtct atcagtagcc tcggaagggg acaggtgaca
     3421 atttctgtcc tgaggtggaa cagagctgtc ctttgcaaca ttctcttaaa gttgggcaaa
     3481 gagttcacac tgtgatgttc acgggagtgg gagggatggg gaaaataaac ttaactctac
     3541 aaaagcaaac tctaatgcat gcaagaacca ttaggttggc aggtatattc ataagtgaaa
     3601 aacctggaag tgtaatggta gaacataaaa cctgtactgc ttctgtttga gtgcaaaact
     3661 gtactagcca atacgctgaa gtgtgtggcc cacaaattga aattttaacc tcaatgtcct
     3721 gtatccatgc tctcatgtgg attcttaact gaggagaaac taactcatcc cgtctcaaat
     3781 gtttctttaa tctgcattct gttctttctt cctggtagtg ccattactag tgttcctctt
     3841 attttctccc ctctgctgaa gacaataaat attcctttga gacccgtgga tccttctgcg
     3901 gaccctaatg acacaaagtg gagctcaact gtcctccctt ctatttcttt ctttctaaac
     3961 ttgaactctg actttgctag acatagaagg ctcagtggtg gaacgttagc gaaatggaga
     4021 ttgacagtat gtgaaggctt agaggcaaat gcataggtgt gtagctgaga gtgctggtat
     4081 ctaatatacc attgtattca ctgacacaaa ataaacacat ttaatcttga aaaaaaaaaa
     4141 aaaaaaaa
//
