LOCUS       NM_212450               6737 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus CTD small phosphatase like 2 (Ctdspl2), transcript
            variant 1, mRNA.
ACCESSION   NM_212450 XM_283758
VERSION     NM_212450.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6737)
  AUTHORS   Wang,P., Zou,K., Cao,J., Zhang,Z., Yuan,W., Chen,J., Xu,J., Zou,Z.,
            Chen,D., Ruan,H., Feng,J., Lin,X. and Jin,H.
  TITLE     Protein phosphatase SCP4 regulates cartilage development and
            endochondral osteogenesis via FoxO3a dephosphorylation
  JOURNAL   Cell Prolif 57 (9), e13691 (2024)
   PUBMED   38886174
  REMARK    GeneRIF: Protein phosphatase SCP4 regulates cartilage development
            and endochondral osteogenesis via FoxO3a dephosphorylation.
REFERENCE   2  (bases 1 to 6737)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6737)
  AUTHORS   Cao,J., Yu,Y., Zhang,Z., Chen,X., Hu,Z., Tong,Q., Chang,J.,
            Feng,X.H. and Lin,X.
  TITLE     SCP4 Promotes Gluconeogenesis Through FoxO1/3a Dephosphorylation
  JOURNAL   Diabetes 67 (1), 46-57 (2018)
   PUBMED   28851713
REFERENCE   4  (bases 1 to 6737)
  AUTHORS   Liu,X., Yu,R., Sun,L., Garibotto,G., Lin,X., Wang,Y., Thomas,S.S.,
            Li,R. and Hu,Z.
  TITLE     The nuclear phosphatase SCP4 regulates FoxO transcription factors
            during muscle wasting in chronic kidney disease
  JOURNAL   Kidney Int 92 (2), 336-348 (2017)
   PUBMED   28506762
  REMARK    GeneRIF: regulator of FoxO transcription factors and promotes
            cellular proteolysis
REFERENCE   5  (bases 1 to 6737)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   6  (bases 1 to 6737)
  AUTHORS   Zhao,Y., Xiao,M., Sun,B., Zhang,Z., Shen,T., Duan,X., Yu,P.B.,
            Feng,X.H. and Lin,X.
  TITLE     C-terminal domain (CTD) small phosphatase-like 2 modulates the
            canonical bone morphogenetic protein (BMP) signaling and
            mesenchymal differentiation via Smad dephosphorylation
  JOURNAL   J Biol Chem 289 (38), 26441-26450 (2014)
   PUBMED   25100727
  REMARK    GeneRIF: SCP4, is a Smad phosphatase and plays a critical role in
            BMP-induced signaling and cellular functions.
REFERENCE   7  (bases 1 to 6737)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK163262.1, AK033382.1, AK039162.1 and BB183048.2.
            
            On Mar 21, 2014 this sequence version replaced NM_212450.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.96646.1, AK033382.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-590               AK163262.1         3-592
            591-4995            AK033382.1         140-4544
            4996-6217           AK039162.1         2415-3636
            6218-6737           BB183048.2         13-532
FEATURES             Location/Qualifiers
     source          1..6737
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.46 cM"
     gene            1..6737
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /note="CTD small phosphatase like 2"
                     /db_xref="GeneID:329506"
                     /db_xref="MGI:MGI:1196405"
     exon            1..617
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            618..827
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     CDS             642..2039
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /EC_number="3.1.3.-"
                     /note="isoform a is encoded by transcript variant 1; CTD
                     small phosphatase-like protein 2; CTDSP-like 2; CTD
                     (carboxy-terminal domain, RNA polymerase II, polypeptide
                     A) small phosphatase like 2"
                     /codon_start=1
                     /product="CTD small phosphatase-like protein 2 isoform a"
                     /protein_id="NP_997615.1"
                     /db_xref="CCDS:CCDS16652.1"
                     /db_xref="GeneID:329506"
                     /db_xref="MGI:MGI:1196405"
                     /translation="MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKN
                     ETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTPRTGEKPDKQLSRVRR
                     KSPVNGEAGSYEMTNQHIKQNGKLEDNPCSGSPPRTTLLGTIFSPVFNFFSPANKNGT
                     SGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTSANGAAYSNQAVQVRPSLNNGLEEAE
                     ETVTRDIPPLTAPVTPESGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPA
                     LPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREF
                     LERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNIL
                     GRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRP
                     HIRDRFRLHDLLPPD"
     exon            828..966
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            967..1116
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1329
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..1408
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1520
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..1607
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1608..1670
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1671..1750
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1751..1877
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1878..1973
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1974..6737
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4001..4006
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /note="hexamer: AATAAA"
     polyA_site      4026
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /note="major polyA site"
     regulatory      6712..6717
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /note="hexamer: AATAAA"
     polyA_site      6732
                     /gene="Ctdspl2"
                     /gene_synonym="D2Ertd485e; SCP4"
                     /note="major polyA site"
ORIGIN      
        1 gcgctctcct tgtcgcccgg ctctaggcgg ttccgttagc ggcgggaggg aaaaccgccc
       61 ccggcgtccc cgcctccgct gctaacgctt tcctccctac tccccctgcg accaccccgc
      121 agcccgctac ggaggccccc gaagtacaaa cgtcccccac gctccgagcc ccatcggagg
      181 ctgagtccag tctaactcct cgggccctaa gctcattttt ttttcattgt tttttgttgt
      241 tgttgtttct tgtttttctt ttggtcagga attcgctctg gtgagttccc taaggcggca
      301 gaaacttcag cctcttcacg gtagtaaaag ttggtttccc ctcccccgct gccgcccagg
      361 cctcccgcat tccttccctc ccgcctctcc ggatcggggc gggcggggga ggagggagcc
      421 agagcgcctg cgcagggagg ccgctttcca tccgggtccc tgtccgtgcg gtgcagcagg
      481 tcggtaggcg ggaaatggcg actggctgaa ggagctggtt ctgttgctgc tgagggataa
      541 gcgggaaaga caccacctat tgcgcagtcg ggaccatcgc cggagcccga agacactttt
      601 ctgtcgtcac agtgaaggtt tacatgtggc acccgtaaaa gatgaagctg agaacacgga
      661 aggcttctca gcagtccagt ccaatccaga cacagcgcac tgccagagca aagaggaaat
      721 actcagaggt tgatgatagc ttgccttcag gaggagaaaa accatcaaag aatgaaaccg
      781 gcttattgtc ttcaattaaa aagttcatta aaggaagcac acccaaggaa gagagagaaa
      841 atccttcgaa gcggagtaga attgaacgtg atatagataa taatttaatc acatcaacac
      901 caagaaccgg agaaaagcct gacaaacagt tgtctcgagt aagacggaaa agtccagtca
      961 atggagaagc tggtagttat gaaatgacaa atcaacatat aaagcaaaat ggaaaattag
     1021 aagataaccc ttgctctggt agtcctccga ggactacatt gttggggacc atattttcgc
     1081 ctgtcttcaa ctttttttca ccagcaaata aaaatggaac gtcaggctca gattccccag
     1141 gacaggctgt ggaagctgag gagatagtga aacaacttga catggaacag gtggatgaaa
     1201 ttactaccag caccacgtca gctaatggag cggcttactc aaatcaagca gttcaagtga
     1261 ggccatcact aaataatggt ttagaagaag cagaagaaac agttacccgg gatatcccac
     1321 cccttacagc accagtaact ccagagagtg ggtactcgtc agcccatgca gaggccacct
     1381 atgaagaaga ctgggaagta tttgacccct attatttcat caaacatgtt ccgcctctga
     1441 cagaagaaca gctaaatagg aaacctgctc ttcctttgaa aacaagaagc acaccagagt
     1501 tctccctggt cttagatctg gatgagacac tagtgcactg cagtctgaat gagctagaag
     1561 atgcagcgct cacttttcca gtccttttcc aagatgtcat ttatcaggtt tatgtgagat
     1621 taagaccatt cttcagggaa ttcctggaac gaatgtctca gatgtatgag atcattcttt
     1681 ttactgcttc taagaaggtg tatgcagaca agttactgaa catactagac cctaaaaagc
     1741 aactggtcag gcaccggctt ttccgtgaac attgtgtttg tgtacaagga aactatataa
     1801 aggacttgaa tatccttggg agagatcttt ccaaaactat aataattgac aactcaccac
     1861 aagcctttgc ctatcagctt tctaatggaa tccctataga aagctggttt atggataaaa
     1921 atgacaatga actcctaaaa ttgattccat ttctggagaa gcttgtagaa ctgaatgaag
     1981 atgtccggcc tcacatcaga gacagatttc gattgcatga tttgctgccc ccagattaag
     2041 ttcagagact tgtcatatca ctgaaggggg ggagagaatg caggaccctt ttggactaag
     2101 acaaaaacat tgccattact gttgaaattt tgcatttttg taccccgtct tgctttctta
     2161 tctttggtgc ccaataataa tcaagggtta cagaaagaga ctctcggatt gaacacatac
     2221 agtgggtagg ctaaaacaga agcgtctgta gagtagacag ctccagtgag actctatgta
     2281 taggacatct gcagctcata acgaattctg tttctgccac cagcagtttg acctgtagtt
     2341 acacaggatt ttatgataat aacagagatg aaagtggact ttcattctct ctctgtttgg
     2401 tgctctcagt gggtttgtag ccactcttct gttacttcac tattctcatt tcaacaggaa
     2461 tggccagtaa aagttgtttt atttttcctg ttaaggttta taaccttttt acatttctga
     2521 cctgtattag attagaatct catgatgcat tccttttagt taaggcgctt catagttttc
     2581 tggaaatagt caatttttag tttttttttt aattatacat ttgaatggcc gttttcctgc
     2641 tttgtctgcc tgcatattgt atatttgttt aaaaatattc tctactttta gtccatgtta
     2701 agtttcattt aaaagatgca tttatatttt gttctgtaat attctactgt aggtgaaatc
     2761 ttcaaaaatc aagagactgg gtagttaaga atatatgaat gactaatatt caaatgattt
     2821 gaatgaacca ttgtgatgac atgtattcca gatggtaata tcttgcaatg gcacacgttt
     2881 aatggataaa ggtatacctc agacttcact gtgctcacta gcctttgagg agaacgagtt
     2941 caggcacctg ttgggcttga ttcggttact gctgcctttg ggttttctcc aggaaggaag
     3001 tattcagcac agtgactcag tatttttact ttgcatgggc tggtagtacc tctgttatgc
     3061 tcccagttac aatcagttta aagctctgtg taacagctgt ggtacctaac ggtggctatg
     3121 cataatcctg tggcacagta cactcccggg ccaccagtgc agtcaatgtg ctcatagtgg
     3181 ttttctatgc tatatgaaaa taagtcgtca cgccttggtt ctctaatgca gctaccacaa
     3241 gaggttgata tttttatagt ggcgtgtaat ctccttttca ggaggctttt tatggaaggt
     3301 agaatttgta aaagtcagta tgctttgcct ctcaactgca ttaacatgcc gcaggctcag
     3361 actgtttttg tgtaaaggat gtcaaagaac ggcacttttt ctaaagagaa gtttgatatt
     3421 ttgtatgctt gttaagaaag tacagtattg gaaattaaag gtggacaatt gataattgag
     3481 gagtatgtca gttaattttt tatgtatatt acctgtttac ttgtacaact tattgtacaa
     3541 attacatgca gcttcatttt caaatgaatc cttaaaataa ggaaatcttt ttaggaaaac
     3601 atttaatttt tgtatttttg attttaaagg catgagttgt cagttttcag tgtattaatg
     3661 aagattttaa cttttcatca ggttgagtgt tttcttacta tattatctgt tgtgtatgta
     3721 gttagcatat tgtgtcactg aactgtttaa aaatctagca tgtagagcaa gcctgttttg
     3781 tggaaaatcc ttattcatta aaaaaaataa tcatggcaga ttttctgcaa aaaaaaaaaa
     3841 agcaaaagca tttgcaattc agattttttt tatttaaaaa aaaaaggtat tttgcttgca
     3901 ggaacaatac tacagattca ttttaatgag aatcttcgaa atgtatttat ctttagggca
     3961 cctgggcatc tttatgctgt ttgtcttatg tctttcttga aataaaatgt aaatatgtta
     4021 cctttacata tgctctttct caaaattgtg aacctagtta atatcttctt gcccccatca
     4081 tttttatgct tatacagcaa accccaaaac ctgtacaaga ttgaattttt gacaaacata
     4141 attgttgaca atgtacttga tcaggaatta agtaaataca gtctcaaagc ccttcccaca
     4201 tcttaaaagg ggaaacactt ataccatagt gcctgtgggc actttaataa taaaaaagca
     4261 ggcctgtgcc aggggaatga gctcctactc agccagtagg tgagtcaaca atacactttt
     4321 gtagagaaat gtaacgtggg aaagtttaca tggcctgaga gttgagacca aattaataga
     4381 ttattttttt ctattacttt gagtaattct aaagttgttg ataacaaagt ttaaagaaga
     4441 ttataaagaa gtttgctggc ttcttttcat tttaataggt ttatctttca atcatatctt
     4501 ttctttgttg gtaactgtag aacgcttcct tttagttaat cagaggtgtg tactttttta
     4561 attgcaatgt gcccagcctg tcagtgcaca cagcacacat gactatagta aatgcagggg
     4621 ccatgggtcc atgaagcaca cagcaagcta cctgtgtaca cattacaact cttaaggacc
     4681 tattaaaatt gtgctatttc cagttatgaa tgtttgactt ttaagacatt cttttaaata
     4741 tttgtatcat tgttagagaa tatttgcttg gttgtatttt ttagacccat gtaatatatg
     4801 tagtcctgac cagatttatt accatttttc tctgggtcct aaaagagatc gatgacaatt
     4861 cgtaaccaga aattgtttta tatttgctag tatgtatatt tatttatcca atggctttat
     4921 ttgtttccca aaattgtttt gggacttgtt gaaagcattg tgtaacttct ataaatggct
     4981 attttcttgt aactgtcagt gatatggatg tgtacattgt ttttatatat atatacatat
     5041 atatatctat atatttctgg gttttttgtt tttttggttt tttagggttt gacttttttg
     5101 tttttaagtt acctttgcca atgactttct gttagctttt cctttcattc agccttctaa
     5161 cagagctcat ttttattatg ttgtcaactt tcctgtaaga gagacttcat ctcatcagtg
     5221 acgaaggcat tccattattc ctacaagtcg tacagcaagc acagactctt cacaaggatc
     5281 acagctcttc cgtgtgtcag tcacttaaag gacactgaag ccttcactcc tgtactgata
     5341 cgatggtgtt atacactacg tcactagcta gttaaggttt tctgacctga cttctctttg
     5401 tcttcctagg tatttatttg ttacctcttt aaatcttgta tgtctaaatt aacttagaat
     5461 agtttcccac cgaataacta tgccaagaac taggaaagaa tgtttatttt atttcccctt
     5521 ataggggaag agtggactgg gaacaaaagt gtaaggccaa aaggccttcg gttatcaatc
     5581 attcactttc ttattcctct catgggctgt atttgcctaa aggtttgggg ggagggggct
     5641 gctttttttt cagtgctgat gtatttgact atgccattgc ttctcatgtc ttcccttgag
     5701 ttgaaagcct gctaggactt tgcataaaat acctaaaagt tctcagagta agaaccacaa
     5761 aactcagtac cttatattca aacgttgctt aaattattga aatctaagtc acattagaat
     5821 acattttcat attcatattt ctgttatctt gaattgaaat tccattgtaa atcaatttag
     5881 tcttttagaa agtttattct agcatatggt tttaatatta gtattttaag ataatatagt
     5941 tgactaccaa acctacctgc taatcagaat ttcactgagg agcttttaaa ctgcacagca
     6001 tcctgaagcc tgggaagcca cctcgtctat acagcaggct tggagagttc tgtgttttta
     6061 aagctttccc agtgatttaa atagataact ttggtatatc ctgttttaaa taatgtggtt
     6121 tgagaatagg ttgcaaaatt tgaccagcca tatttccctg tctctctgtc tctgtctctc
     6181 tttctctctc tggtagtttt tttttttttt tttttttaag tgctgggatc atatttcaca
     6241 gaacgtattc aaattcgtgg aggaataatg aagattgagg ctactgctca ttgccagttt
     6301 tgtcattcat acttttaaat taagagtttg catttataga actctgaata gctgatcatt
     6361 tacatagctg aaggacatgt ccctgaatga gaccattata tatattaact aaaatatttc
     6421 actatttttt tattttataa atctttgtag aaataagcaa tgaaatgcta ctttcatctt
     6481 ttgaactggg atttttcaag gttgtgtcct tttggcatta aggtaggggg gagttaatat
     6541 tctctctact tatttccaca tgaatcaata tgaagtcgtg gacatttaaa aatctcaatt
     6601 taatttctac ttatttacta tgcagtatag ccgtgaacaa gtaatgtaga tttagttttc
     6661 tcatcttcaa atgccctgat taccctacct cacagggttg ttgtggggat aaataaaact
     6721 tttatggaag tactttc
//
