LOCUS       NM_133710               4627 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus CTD small phosphatase like (Ctdspl), mRNA.
ACCESSION   NM_133710 XM_916441 XM_924261 XM_924264 XM_924267
VERSION     NM_133710.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4627)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4627)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 4627)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 4627)
  AUTHORS   Zhu,Y., Lu,Y., Zhang,Q., Liu,J.J., Li,T.J., Yang,J.R., Zeng,C. and
            Zhuang,S.M.
  TITLE     MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S
            transition by activating the pRb protein
  JOURNAL   Nucleic Acids Res 40 (10), 4615-4625 (2012)
   PUBMED   22210897
REFERENCE   5  (bases 1 to 4627)
  AUTHORS   Tang,F., Kaneda,M., O'Carroll,D., Hajkova,P., Barton,S.C.,
            Sun,Y.A., Lee,C., Tarakhovsky,A., Lao,K. and Surani,M.A.
  TITLE     Maternal microRNAs are essential for mouse zygotic development
  JOURNAL   Genes Dev 21 (6), 644-648 (2007)
   PUBMED   17369397
REFERENCE   6  (bases 1 to 4627)
  AUTHORS   Tsuda,M., Kiso,M. and Saga,Y.
  TITLE     Implication of nanos2-3'UTR in the expression and function of
            nanos2
  JOURNAL   Mech Dev 123 (6), 440-449 (2006)
   PUBMED   16806845
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK013115.1, AC156800.2, AA239542.1 and AC055818.9.
            
            On Mar 29, 2008 this sequence version replaced NM_133710.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK013115.1, AJ344340.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-240               AK013115.1         1-240
            241-321             AC156800.2         89735-89815         c
            322-434             AK013115.1         319-431
            435-865             AA239542.1         126-556
            866-1337            AK013115.1         862-1333
            1338-4627           AC055818.9         185880-189169       c
FEATURES             Location/Qualifiers
     source          1..4627
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 71.07 cM"
     gene            1..4627
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /note="CTD small phosphatase like"
                     /db_xref="GeneID:69274"
                     /db_xref="MGI:MGI:1916524"
     exon            1..405
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /inference="alignment:Splign:2.1.0"
     CDS             327..1157
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /EC_number="3.1.3.16"
                     /note="carboxy-terminal domain RNA polymerase II
                     polypeptide A small phosphatase 3; CTDSP-like; NIF-like
                     protein; small CTD phosphatase 3; NLI-interacting factor
                     1; small C-terminal domain phosphatase 3; nuclear LIM
                     interactor-interacting factor 1; CTD (carboxy-terminal
                     domain, RNA polymerase II, polypeptide A) small
                     phosphatase-like"
                     /codon_start=1
                     /product="CTD small phosphatase-like protein"
                     /protein_id="NP_598471.3"
                     /db_xref="CCDS:CCDS23605.1"
                     /db_xref="GeneID:69274"
                     /db_xref="MGI:MGI:1916524"
                     /translation="MDGPAIITQVTNPKEDEARSPVAGEKASQRNISLKKQRGRSILS
                     SFFCCFRDYNVEAPPANSPSVLPPLVEENGGLQKGDQRQVIPVPSPPAKYLLPEVTVL
                     DYGKKCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQ
                     LFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKV
                     IIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCSR
                     "
     exon            406..560
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            561..593
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            594..695
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            696..752
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            753..845
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            846..1031
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..4627
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4608..4613
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /note="hexamer: AATAAA"
     polyA_site      4627
                     /gene="Ctdspl"
                     /gene_synonym="2810418J22Rik; HYA22; SCP3"
                     /note="major polyA site"
ORIGIN      
        1 gctccgcgct cgctccttct ctccgtcgcc tgctcgcgct tcccgcggcg ccgggcctcc
       61 cgctccgcct ccccgagcgc ggctctcccg ggcgcggctc cggggttcat gctgacgagg
      121 cggcggccgc ttcagcccag cggcggcggc gacggcggga gctggggcgc gggccccggc
      181 cgcctctctc ggagcgcggg gccgggcggc ggcgagcgcc ccaccgcgcc gcgcccctgc
      241 gcgcccccta cgccgcgccc ccgcgcgccc cccgcgccta gcctgcgggg ggccgggcct
      301 gcgggcggcc ggcgcggcgc gcacccatgg acggtccggc catcatcacc caggtgacca
      361 accccaagga ggatgaggcc cggtcgcccg tcgcgggcga aaaagcttcc cagcgcaaca
      421 tcagcctaaa gaagcaaagg ggtcggagca tccttagctc tttcttctgc tgcttccgag
      481 actacaatgt ggaagcccct ccggccaaca gccccagtgt gcttccgcca ctggtggagg
      541 agaacggtgg gcttcagaag ggtgaccaga ggcaggtcat tcccgtacca agcccaccag
      601 ctaaatacct ccttccagag gtgacggtgc tcgactatgg aaagaaatgt gtggtcattg
      661 atctagacga aaccctggtg cacagttcgt ttaagcccat tagtaatgct gacttcattg
      721 ttcctgttga aatcgacgga accatacacc aggtgtatgt gctgaagcga cctcacgtgg
      781 acgagttcct ccagaggatg gggcagctct ttgagtgtgt gctctttact gccagcttgg
      841 ccaagtatgc agaccctgtt gccgacctcc tggaccgctg gggtgtgttc cgggcccgac
      901 tcttcagaga atcctgcgtg ttccaccgtg ggaactatgt gaaggacttg agtcgcctgg
      961 gacgggagct gagcaaagtg atcatcgtgg acaattctcc tgcctcctac atcttccatc
     1021 ctgagaatgc agtgcccgtg cagtcctggt ttgacgacat gacagacacg gagctgttgg
     1081 acctcatccc gttcttcgag ggcctgagca gggaagacga tgtctacagc atgctgcaca
     1141 gactctgtag caggtagccc tggccttggc ccatctgtgc ctgtgcactc tggaaccctg
     1201 gctcagggga cccgcccggc ctcggctcac tgagtgcagc ccaggaagac tccgtgctcc
     1261 gggccacagg gtgaatgtca ccatgcctac ctggtttgtt ttgttttgtt tttttaaaga
     1321 acagaaacaa ctattttaaa ggaaaaaaaa aaactctttt aatagatttc ataaacggac
     1381 tgcattttac aagattcgat tttcttaaaa acataccaaa aagaaaaaga aaaaaaaaga
     1441 agaagaaaag aaaagcaaaa actttgatat ctcccgactt cctttcaact gacctcccct
     1501 tccaagcaga caaacctgtc ctcttggtcc cggtttggag cagctgaccc aactcagaat
     1561 ctctttccta caggatgaag tgcctttttg aatgttattt taagctgaaa gttaattttt
     1621 ttgtatacag cctatttcca aacatctttt agtcttttac ggtcttagat acttactctg
     1681 agaagacgaa caggacaatt ttatagaccc cggtagcctg tgtgtggtgg ggtaaggatg
     1741 tggtcgggga gagcaacggg tcacaggagc ccgcctccca acatgagtga ctgtcaaccg
     1801 tggcgtgcat gggatctcgc tccccctgac atgacttttc tcctgactgt ccttgtgtcg
     1861 tttccgacca ggctggaatg tacctgccaa tggcccaatg ctttatgaaa cagccggttc
     1921 cttttatgat ggtttctgag gttgttaaaa atgtgtcttg aggttgcatt tttgcccttg
     1981 ggaagtgaca ttgtatcgtc acatgtgctt tcccatgact ccacgtgtct gtcccttgtt
     2041 gttctgttgt cgttggtttg aggagagcag ttagagaaag ccctgaagcc cttggatcta
     2101 ttaagtcctt cctttcagaa gctgggtgca catggagctc gctgttcgga ctccgctgct
     2161 actgcgctcc tgacaccaaa tggaactgac cagcggctgt cacactgttc cttagccact
     2221 gtgcctatgc ttagaagatg ctcaccgctc agctgcagac tcagacaggg tcacagacag
     2281 gtgtcccacc ccatcaagca cggcaccctt ctttggcccc cagccaccgc caagaatgcc
     2341 gaagggcaca aaagtttggg gacaaaaaca aaactgaagg gccaaagcac cgctcaggtg
     2401 cggcatggcg ttcactttac actgcagtca acatcagagc ctaagctgga actcgcctgt
     2461 ctcacctgag aacctgtggc ctcaaccagc cgccatgctg gtgtggctca agtcacctct
     2521 cagcctcttt ggaagcacag cctcttcgag ccaagggttg gagaagcctg ccttgatggg
     2581 agactcatct ctccaaacca gggagaaggg cttctccctg gagcctgggg gtctcttccc
     2641 acccgttccc agtttggtgt ttaatctgtg ttacatcgac cctctgaaga acgaacagag
     2701 cccttttgtg ttggcaccaa tgccttagtc ctctgtgggt tgggcctcag ccagaattct
     2761 gctgggagtt gctggcgttg acaagattta aagtcagggg tcaaactttt aaaaatatat
     2821 atattatttt tctttccttc acaaaataac gaagccagct actaggcctg tcttcccaca
     2881 gtgcttggtc cggggaacca ctgtgcagtc agaacggaga cacgtcagtg tcgtttagat
     2941 cacctgactg agtgttccga acccagcgag ccccgtgcca attaaaaccg agactgcccc
     3001 tttgctaaga aatcatttcc acaggtaacg acagttacgc ggcagatccg cacacgccat
     3061 caaccctcat ggaaaaccag tcattagctg ccttaagtgt cttgggtgtt tcagagtctg
     3121 ccatgtgttg acttccacac agaacaaggc ccggatggaa cctcagatct ttgcctgtgc
     3181 ctctttgtgt cggtgtcacg gggccttatt tgaaaagggg ggcagaatgg actgcgattc
     3241 cagaatattt caggggaagc gagcgtagaa atagtgctct gcttcagaca ggttcgaggc
     3301 caacccttgg ccttacagcc ccggggctgc gtgtgcccat gccctccggg cagagcttcc
     3361 aggtgggagc cccgttcttg ccaccacaaa catggaatgt cttgggtggg tggcagagct
     3421 tctgagggct ctgaaatctg caccttatct gaccaagctc caataatgcc aatttttatt
     3481 tccttttttt ttttttgaaa acaaatccgc tttatgtaca taattgaaaa aaatctatat
     3541 ttttaatcag ttacgtgtaa atgaagcaat agaactctaa caaggccaag aaaggagacg
     3601 aatgttcgag gtttattttc ttaaggtaaa tacgggtatt gcttttaatt gtaagtttat
     3661 taaaatgcgg gcttgagaac gtatcagcca tttctctgtg ccatatcctt cccacgttac
     3721 caaaacactc catctcttta gccaaaagaa acccctgacc tctcaagtcc cgtggtcctc
     3781 tcagctccgg gttaggaccc ctctcttaga caagcgcttt cgatgcgagg gtctaggaca
     3841 gggtggcttg ggttggtgga ctccagccta cacctttagc ttgacctcaa gtggggcttc
     3901 ctgacccctg acccctgacc cctgaggatg ttaatgttct tgtcttccat ttgttctgga
     3961 atcctccatg tcggtctgtg gtcccctgca ctagctgttt gtaaacaata cgtttgtatc
     4021 ttaatcacac cacctgtcac cgatggcagt gggtgaagat cctgctgaca cggtgcgatg
     4081 ttgtgaggtg actttgggga catgaggacg tccacatgac actaaatcat cccggtcaca
     4141 gcatgtgaag ttgggggtac ggagatgaat cctaaaagtg tgtagagcct ggcagcattt
     4201 tacaaccctg tatttcaaag acggctttct aataaaatcc agaaacacac agccctattg
     4261 gtcaaacact cgtgacgttt gtgcctctgc tcctcacggt gctgtgctgg acagctggca
     4321 tgccagggtt tgagaagagc ggatggccta ccgtgctcgc ggttccctgg gcaaacttgc
     4381 tggctgcctc tgttcctatt ttactgtaaa tctgaccatg tctatccctg gagtcgccct
     4441 gaggataggt tccccccagg ggtggtgatg ttggtgtctg gggagttaca gttttctgct
     4501 ggatgtttga atgtgccgtc ccagtgccac ttgggaaata ccacatgttg ggatgtgcac
     4561 gatgctcggg gcaagtattg tcaatcagtg atttccctcc tgccaaaaat aaactcgtca
     4621 aactgca
//
