LOCUS       NM_001113470            4823 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus CTD small phosphatase 2 (Ctdsp2), transcript variant
            a, mRNA.
ACCESSION   NM_001113470
VERSION     NM_001113470.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4823)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4823)
  AUTHORS   Zhang,H., Zhang,L. and Sun,T.
  TITLE     Cohesive Regulation of Neural Progenitor Development by microRNA
            miR-26, Its Host Gene Ctdsp and Target Gene Emx2 in the Mouse
            Embryonic Cerebral Cortex
  JOURNAL   Front Mol Neurosci 11, 44 (2018)
   PUBMED   29515367
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4823)
  AUTHORS   Bolt,C.C., Negi,S., Guimaraes-Camboa,N., Zhang,H., Troy,J.M.,
            Lu,X., Kispert,A., Evans,S.M. and Stubbs,L.
  TITLE     Tbx18 Regulates the Differentiation of Periductal Smooth Muscle
            Stroma and the Maintenance of Epithelial Integrity in the Prostate
  JOURNAL   PLoS One 11 (4), e0154413 (2016)
   PUBMED   27120339
  REMARK    Erratum:[PLoS One. 2016 Jun 3;11(6):e0157283. doi:
            10.1371/journal.pone.0157283.. PMID: 27257811]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4823)
  AUTHORS   Kloet,D.E., Polderman,P.E., Eijkelenboom,A., Smits,L.M., van
            Triest,M.H., van den Berg,M.C., Groot Koerkamp,M.J., van Leenen,D.,
            Lijnzaad,P., Holstege,F.C. and Burgering,B.M.
  TITLE     FOXO target gene CTDSP2 regulates cell cycle progression through
            Ras and p21(Cip1/Waf1)
  JOURNAL   Biochem J 469 (2), 289-298 (2015)
   PUBMED   25990325
  REMARK    GeneRIF: CTDSP2 induces p21(Cip1/Waf1) through increasing the
            activity of Ras.
REFERENCE   5  (bases 1 to 4823)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4823)
  AUTHORS   Zhu,Y., Lu,Y., Zhang,Q., Liu,J.J., Li,T.J., Yang,J.R., Zeng,C. and
            Zhuang,S.M.
  TITLE     MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S
            transition by activating the pRb protein
  JOURNAL   Nucleic Acids Res 40 (10), 4615-4625 (2012)
   PUBMED   22210897
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC085142.1, AK049271.1 and BB731474.1.
            
            Transcript Variant: This variant (a) represents the longer
            transcript and encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085142.1, AK049271.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2064              BC085142.1         1-2064
            2065-4816           AK049271.1         1865-4616
            4817-4823           BB731474.1         418-424
FEATURES             Location/Qualifiers
     source          1..4823
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 74.35 cM"
     gene            1..4823
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /note="CTD small phosphatase 2"
                     /db_xref="GeneID:52468"
                     /db_xref="MGI:MGI:1098748"
     exon            1..585
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             522..1334
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /EC_number="3.1.3.16"
                     /note="isoform a is encoded by transcript variant a;
                     carboxy-terminal domain RNA polymerase II polypeptide A
                     small phosphatase 2; small C-terminal domain phosphatase
                     2; nuclear LIM interactor-interacting factor 2
                     (NLI-interacting factor 2) (Protein OS-4); CTD
                     (carboxy-terminal domain, RNA polymerase II, polypeptide
                     A) small phosphatase 2"
                     /codon_start=1
                     /product="carboxy-terminal domain RNA polymerase II
                     polypeptide A small phosphatase 2 isoform a"
                     /protein_id="NP_001106941.1"
                     /db_xref="CCDS:CCDS48711.1"
                     /db_xref="GeneID:52468"
                     /db_xref="MGI:MGI:1098748"
                     /translation="MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRSIFKALLCC
                     FHTQHVVQSSSSTELTHKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEQDQGRIC
                     VVIDLDETLVHSSFKPINNADFIVPVEIEGTTHQVYVLKRPYVDEFLRRMGELFECVL
                     FTASLAKYADPVTDLLDRCGVFRARLFREACVFHQGCYVKDLSRLGRDLRKTVILDNS
                     PASYIFHPENAVPVQSWFDDMADTELLNLIPVFEELSGTDDVYTSLGQLRAP"
     exon            586..731
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /inference="alignment:Splign:2.1.0"
     exon            732..770
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /inference="alignment:Splign:2.1.0"
     exon            771..872
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /inference="alignment:Splign:2.1.0"
     exon            873..929
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1022
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1208
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..4823
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4794..4799
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /note="hexamer: AATAAA"
     polyA_site      4817
                     /gene="Ctdsp2"
                     /gene_synonym="D10Ertd73e; OS-4; OS4; SCP2"
                     /note="major polyA site"
ORIGIN      
        1 aaaatagcaa acctctgcag ggtccgcggc ccccgctgct cgccggagga gggtcccggg
       61 gcctaggacg ctggcctgga gcggaacgcg ccggcaggcg gcgaagaggc cggcccaaga
      121 tctgggagga gcgcgggggt gggcgctgca gccgcgggtt gtttatctgg agtacggagg
      181 ggagggggga gcctggaaac cgccccgtgt cccatttcct cctcttgttt tcgctccgga
      241 ttctccatgt tggacccaaa ctgaggagcc cggagctgcc accgggggat cggggctggg
      301 ggcaccgggg aagccgccgc ctggcccgcc cgccctctgt gcaggccgcc tcccttcccg
      361 gcccggggag gaaacgcgag ggggatgtga acagctgcgg gagtcggagt ctcgggagcc
      421 ggagcccgac gggcccccgc ccaggccccc cagcccagcc cgcctgcgcg cccgcccgcg
      481 cgtcctcccg cccagccagc ccgggcccgc gggattgtta gatggaacac ggctccatca
      541 tcacccaggc gcggagggaa gacgccctgg tgctcaccaa gcaaggccta gtctccaagt
      601 cctcgcctaa gaaaccccgt ggccgcagca tcttcaaggc cctcttgtgc tgtttccaca
      661 cacagcatgt tgtccagtcc agctcttcca ctgagctcac acacaaggag gaggccaaca
      721 ccatcgccaa gtccgatctc ctccagtgtc tccagtacca gttttatcag atccctggga
      781 cctgcctgct ccccgaggtg acagagcaag atcaaggcag gatctgcgtg gtcattgacc
      841 tggatgagac ccttgtgcac agttccttta agccgatcaa caatgctgac ttcatagtgc
      901 ctgtagagat tgaggggacc acgcaccagg tatatgtgct caagaggcct tacgtcgatg
      961 agttcctgag acggatgggg gagctcttcg aatgtgttct cttcactgcc agcttggcca
     1021 agtatgctga ccctgtgact gatctcctgg accggtgcgg ggtgttccgg gcccgcctgt
     1081 tccgagaggc ttgtgtgttc caccagggct gctatgtcaa ggacctcagc cgcctgggaa
     1141 gggacctgag gaaaactgtc atcctggaca actcccctgc atcttacatc ttccacccag
     1201 aaaatgcagt gcctgtgcag tcctggtttg atgacatggc agatacagag ttgctgaacc
     1261 tgattccagt cttcgaggag ctaagtggaa ctgatgatgt ctacaccagc cttgggcagc
     1321 tgcgggcccc ttagccttcc tgctccaaga aacggccatc ccaacagggg actctgctac
     1381 actgtgcctt tgtggtcagc ctcactgacg gggtctgcaa gtagccaggg cgtgtgggac
     1441 aaaagcaggt cacacgcaga gcaggaaatc agaccaagac ccagagctct ctgcaccccg
     1501 tgctcagttc ccaggtggtt gtgtgggtgt gtgtgcgtgc atgtgcccgt ccggtaaact
     1561 atggtcctgg gtgcccagtt gtgcagtagg gggagaagct gaaagataag gactcaaccc
     1621 aagtcatttg tcttctttcc tgctatgctg tgagctactg agctttacag ccatgaaaac
     1681 tattgtaggc tccctcgcca aaccatggct ttccctcagc atcaagacct gtgccaagga
     1741 gaagggagag gccggaggct gctttggatg cccagacaca catctttcag aaaacacaga
     1801 aacctagcca gcagctgcag acatgtttgg gaatatgaga gcatgttcgc agacccacca
     1861 ggttctgtgt cctatgggct acacctggct ccagcaagaa tgcctgccat gggcacttct
     1921 ctgtacccgg gctccagtgc caggccagcc tctcactccc aagccatagt cctactccca
     1981 tgggaaagga ggtcttctct ctgccctgga ggaggacata tagctgattt ctgttctttt
     2041 aactcttaaa aatctctttc taaacttgga gtggtttata ttcgcccgag ctccagtcct
     2101 gggcctgagg tttgtgtggg aagcgctggg gtacaaagaa aatgcaaatg ttcaatgcaa
     2161 gatgtctgtc tccttgcgtg tagatcccaa aagtgctctt caggggttct gtgctagctg
     2221 atgcaaggac attagctcca aaggctgggg agggcttggc tctccctctg tgtcttcctg
     2281 gtgtcccgcc ctggccagct ctcgtctgct ctcgccttta tccttctcgg ctgctgctct
     2341 tcctctccag agccttggga gaaggacttt ccccggttgt acttaattga ttggttgtcc
     2401 caagtgttgc tcttacttga tttgccaaat gcctcctgct tctcgttata ggactgagtg
     2461 aggtcctcat agctctgtgc tctgggcagc tctgagctct cagccctgtt gctttcaatg
     2521 tcagtcacag agtggaagtt tccccaaagt ggaaagctac cattgggaac acaaggggcc
     2581 cctgaggggc ctccacctca ctgccttaag tgagtcccgc ccactccctg cctccctccg
     2641 aggtgggcgg gagttcctac cccatctctg cttcccctgg aggccggcca gcgtttgtgg
     2701 gttggttcag gtgtggtacc tcccactcag gagtcaatat tttcaaattt ttctagtttc
     2761 cacacacgag gtcctgcctg gggtttgaga aagcctggtg gaggagtgtg gtggtgtgag
     2821 tggagactgg ctggcattcc tccagcactc tgcagacttc ttcctgggcc cgaggctatg
     2881 gagccttggc tttcacttct gtgacaaaca catgccattt ccccagcctc atttgctggt
     2941 gtctgtaggg tcctcccaag gtgagctgag ggctgcaggt gctagccagg aacatgggag
     3001 cttgactgtg gcttcaggtc cagaccctga tctcactggc atcccaatac tgcaggaggg
     3061 gtcttctcac aaagctctga gggctggtct tgactaagca ataagagcct cagagttgat
     3121 tgaattttaa ggtccctttc tggcttcttg gttctccatg tgaccaaagc ccagtgtggc
     3181 ttcatgggag ccctgttact tctccatgaa accccagctc tctaggcctg actgccacca
     3241 gagtcctctt accacctgca gtctgccaca aagatgccat atcaactcct ctcttcccaa
     3301 aactaaacag gatctatcat ggtggcacgg agtcagctag atgttgtctc ttgctatccc
     3361 tgtgctagtt ccatgtttta gaagcaaagt gatactgggg aggagaggag ggcaagtgag
     3421 aggagccagt gcctcctgaa gcccttgctc cactgccacc agcccgcctg ccccagtgca
     3481 gactggtctt caggagtcag tagaccaccg gaccaggtgt cagcatccac tccaagccat
     3541 gctaggaatc tgccccctgc cgggttcagc tctttaaggt gcctcttcag ggacacagtg
     3601 tgtgtctgat tgggcttcgc atcaaaagcc tgacgttcct gtccctctta tagggggagc
     3661 tttggacaca ggaccagttt gataaagggc caggtaaggg tttccactct gcacattgta
     3721 gaggggacac cgaaggccca tgggtcccta attaaagaag ttgagtgaat ttgccttcgt
     3781 tcaaccaggg acctatctca ctccctccca aagatttttg tataattgta taacccccct
     3841 ccccctgtta acagtggctc agaaaagctt tgtactaaaa gcatgggacc ctcacagcaa
     3901 ccattcctgg gagatgggtc ccttataggt ccatgacctg ctctgttcag aggcctcttg
     3961 gcagtgtggc ctgtttgtgc tgtcctgcat ccagtgtgtt ggcctggcta agtgaaaacg
     4021 gtgagctgtt tcccctttgg gctacttaac cacggctact ccttttttaa aaatgtccta
     4081 gttctcccct acacacacac acacacacac ggtttgatga atttccaaac cacggctact
     4141 ccttttttaa aaacgggttt gaactcctgt ttagccaaga gtgatcttga gctggtctcc
     4201 tgcctccacc ccctgagtgc tggggttaca ggtgatagct ggtctcctgc ctccacctcc
     4261 tgagtgctgg ggttacaggt gatcgctggt ctcctgcctc cacctcctga gtgctggggt
     4321 tacaggtgat cgctggtctc ctgcctccac cccctgagtg ctggggttac aggtgtgatc
     4381 accttgctgg cttgtgaggt gctggggaca acccagggct tcgtgcatgt caggcacaca
     4441 ctcccaacta agctacatcc ccagtccctc tttctagaaa acagataagt ccatgttcag
     4501 gggagaagag gtcacaggtc aggccagctg ccccatcctt tagttcgggg ttagctccca
     4561 gaactgccct gcaccataag ctggtgattc tccatgcctg tccttacccc ggatctggct
     4621 attcccgtga tgccatttgg aggggagagg tctgcttccc actgtgacca ggctatggga
     4681 tccttggcca ccttgcttca tgatttgata catttgttgt attcaaaaac ttgaactgta
     4741 ggatgccatt aagagtctgt ttatattttt ggaatatttg tattacaatt gttaataaag
     4801 gctggtttaa aaacctgtgc agg
//
