LOCUS       NM_153407               4126 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus cysteine-serine-rich nuclear protein 2 (Csrnp2), mRNA.
ACCESSION   NM_153407
VERSION     NM_153407.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4126)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   2  (bases 1 to 4126)
  AUTHORS   Gingras,S., Pelletier,S., Boyd,K. and Ihle,J.N.
  TITLE     Characterization of a family of novel cysteine- serine-rich nuclear
            proteins (CSRNP)
  JOURNAL   PLoS One 2 (8), e808 (2007)
   PUBMED   17726538
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC139571.2.
            
            On Nov 17, 2006 this sequence version replaced NM_153407.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC035295.1, AK146924.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-206               AC139571.2         50596-50801
            207-438             AC139571.2         56169-56400
            439-698             AC139571.2         57631-57890
            699-995             AC139571.2         61089-61385
            996-4126            AC139571.2         63135-66265
FEATURES             Location/Qualifiers
     source          1..4126
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 56.32 cM"
     gene            1..4126
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /note="cysteine-serine-rich nuclear protein 2"
                     /db_xref="GeneID:207785"
                     /db_xref="MGI:MGI:2386852"
     exon            1..206
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /inference="alignment:Splign:2.1.0"
     exon            207..438
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /inference="alignment:Splign:2.1.0"
     CDS             288..1892
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /note="TGF-beta induced apoptosis protein 12"
                     /codon_start=1
                     /product="cysteine/serine-rich nuclear protein 2"
                     /protein_id="NP_700456.1"
                     /db_xref="CCDS:CCDS27839.1"
                     /db_xref="GeneID:207785"
                     /db_xref="MGI:MGI:2386852"
                     /translation="MDAFSGSGLKRKFDDVDVGSSVSNSDDEMSSSDSADSCDSLNPP
                     TTASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSV
                     RSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDE
                     DIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCR
                     LYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKL
                     ELESKRQVSRPAAEEEPLPGAQSSQTQDFQEFIAENETAVMHLQSAEELERLKAEEDS
                     SGSSASLDSSMESLGVCILEEPLAVPQELCPGLAAPILIQAQLPPGSSVLCFTENSEH
                     PAASPMSSPSYLNSGPLVYYQVEQRPVVGVKAESGSEEGPASFPKEKDLSVFSLPVTS
                     LVACGPSASAALCKPEVGKTSSLNKLLPEDCGLKEPESEDLHPSWSPSSLPFRTDNEE
                     GCGVQNSQQSEDRTSEDSALELPLAV"
     exon            439..698
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /inference="alignment:Splign:2.1.0"
     exon            699..995
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /inference="alignment:Splign:2.1.0"
     exon            996..4126
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4105..4110
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /note="hexamer: ATTAAA"
     regulatory      4109..4114
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /note="hexamer: AAGAAA"
     polyA_site      4123
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
     polyA_site      4126
                     /gene="Csrnp2"
                     /gene_synonym="Csnrp2; CSRNP-2; taip-12"
                     /note="major polyA site"
ORIGIN      
        1 gttctggtct tcgctgcccg gggagccaga gtgcagagcc gcccgacccc cgccgcctgc
       61 cggccggccc acacaccctg cagccccgag agccacgcga cgggcctggg agccggcacg
      121 cctcggtctc ccctccttgc acacgggctg agtaggcagc gggggcggcg gagaccgtga
      181 cgggagaagc ggctgcggcg gggccgagtc ctcatgttcc tggctagctg gtggtgagca
      241 gcttggggcc atcgtgcttg gctccccgcg gacaactttg gaagccaatg gatgcgttct
      301 ccggctcagg cctcaagagg aaattcgatg atgtggacgt gggctcgtca gtctccaact
      361 cagatgatga gatgtccagc agtgatagtg cggacagctg cgacagcctt aaccctccta
      421 cgactgccag cttcacacca acatccatcc tgaagaggca gaagcagcta cggaggaaga
      481 atgtccgctt tgaccaggtg actgtgtact acttcgcccg gcgacagggc ttcaccagcg
      541 tgcccagcca gggtgggagc tccttgggaa tggcccaacg ccataactct gtacgcagct
      601 acaccctctg tgagtttgcg caagagcagg aggtgaacca tagagagatt ctccgtgagc
      661 acctgaagga ggagaaactt cacgccaaga aaatgaagct gacgaagaac gggaccgtgg
      721 agtcagtgga ggccgacggc ttgacactcg atgatgtctc ggacgaggac atcgacgtgg
      781 agaatgtgga ggtggacgac tacttcttcc ttcagcccct gcccaccaaa cggcggcggg
      841 ccctgctcag ggcttccggg gtccaccgga ttgacgccga agagaagcaa gaactcagag
      901 ccatccgcct gtctcgggaa gagtgtggtt gtgactgtcg gctgtactgt gacccagagg
      961 catgcgcctg tagccaggct gggattaaat gccaggtgga tcgaatgtct tttccgtgtg
     1021 gctgctccag ggatggctgt ggaaacatgg ctgggcgaat tgagtttaac ccgatccgag
     1081 tgcggactca ctacctccac accatcatga agctggagct ggagagcaag cggcaggtga
     1141 gtcgcccagc agcagaggag gagcccctgc cgggagcgca gagctcgcag acacaggact
     1201 tccaggagtt catcgccgag aacgagactg cagtgatgca tctgcagagt gcagaggagc
     1261 tggagcggct caaggccgag gaggactcga gtggctctag cgctagcctg gactccagca
     1321 tggagagcct gggcgtgtgc atcctggagg aacccctggc tgttccccaa gagctgtgcc
     1381 caggcctcgc ggcccccatt ctcatccagg ctcagctgcc cccaggttcc tccgtcctgt
     1441 gttttactga gaactcagaa cacccagctg cctccccgat gagcagcccg tcttacttga
     1501 acagtggacc tctggtgtac taccaggtag agcagaggcc agtggtggga gtgaaagcag
     1561 agtccgggtc agaggaaggc ccagcctcct tccccaaaga gaaagatctg agtgttttct
     1621 cgctccctgt tacctcactg gtggcttgcg gcccttcagc ctcagctgct ctctgtaagc
     1681 cagaggtggg gaaaacatcc agcctcaaca aactcctgcc cgaggactgc ggccttaagg
     1741 agcctgagag cgaggacttg cacccctctt ggtctccctc aagcctaccc ttccgaacgg
     1801 acaatgaaga aggctgcgga gtgcagaact cccagcagag tgaggaccgg acctctgaag
     1861 actcagccct agaactccct ctggcagtgt gacctgagat acatgtccat tctctattta
     1921 ttatctaaca ccatttcaaa acaagactgc tgctcccagg ttattttgtt ggaagtctta
     1981 ggaaaatggg taggaaagga ttgttagtcc atgtgtttct gagagagcgt tcccaggaga
     2041 ccagccccag ctgcagtgtc ccgtaccgag ctctctgggc cgccagaaca aagatgtcga
     2101 tcacagagtg agctgggcag ctcaagcagc tctttatgcc tagtgccaga accaaggatg
     2161 cgagcagctc cctgcaccac atgctggctc ctcaaacacc ctgtcttctt gtagcagcca
     2221 ctttagtgga aaggccactc agctgagtct agaacggaga ggaggcccca gaagagtgct
     2281 tcgatacaaa actcccagga gctttaaacg tttattctgc cccaacccct tggtgtttcc
     2341 tgacctgatc tgcaaactgg ggatccctgg tctgtacctg aattctttct ttcatatgtg
     2401 cttcggcacg agagtgaaac atctgtcttg gaaggtgaaa tgcaggctgg gtagggatgt
     2461 gacttgcaca tggggcaggg tccagtatgg aacagtctgg aagatggttt tgtcaagctt
     2521 gctctctcac ctagtgcaac acacacacac atccactctc tccttttggt ggggggtctt
     2581 ggctctgaat ggaatgtgca ctgcagtaca ggtcatcgag acataggact cttccctctg
     2641 taactgccct cacggccatt cttggttgtg tggggttaga aagttctttg gagtttacag
     2701 ttcaatccca agagtggcac gtgtgttttg gagccttcca tcttggagat tcatgaaaac
     2761 tggaagtcag actgcttctt agttatgaca taggagtccc acattccaga ggattccgga
     2821 tcacattata ataatgacgt ggatgcctgg gactcagact caacacttac ctcagcagaa
     2881 gagctgctcc tctcgtgagc tcgggcagtt ccgaggtccc catttagcac gggcttcttg
     2941 attggcagtg ctacctctgc ctcctggtta aatggcggca gtaggagcaa aacgcttttc
     3001 tcttatcatt ctttaccaag catcaaaacc acaaacttgt tttcttttct tttcttttct
     3061 tttcttttct tttcttttct tttcttttct tttttctttt ttttttttta ggcagtgtgt
     3121 tgctaaacag ccctggctgg cctgggactt gctatgtaga ccaggctggc ctccaaccta
     3181 gtcatgcatc ctgagtgttg tgactgcagg tgtacatctc ttcacttggc tttatctatt
     3241 tatttatttt tggtgagata ataaggccct ggtgtcataa acaatcaatg tatgtggcag
     3301 cagaaacatc tgaaaaaatc cctgaatcct aagcccggag gaccttgtat ttaactggat
     3361 gctggtgttc tgcccattct gccactgtct cttcttgggt ttcattggct tttgtttttg
     3421 tttttgtttt tttggctgca cttcttaagt gagtgcatag gctctctctc cagtctcact
     3481 agagttatct gagaaggtca aggtgttctc aaccctggct agacctctca gactcaagct
     3541 tagctgagat gatgttgatg caaagaagaa tctttttgaa agtttgttgg gacaggaggg
     3601 gactcggccc cctacctcct taagactcca actttcttag cccttagatt tggattttca
     3661 ttaagaaacg taaagactag ccaaccccaa gatatttcta tataactaat ttcttattct
     3721 aaatgcattt cattaattcc atgtcgattc aaactgaccc caacttctga gtgctaaact
     3781 tagcgttgac aatgtcaagc aaagaacctc ttctacaact cagtccatct cagttctggt
     3841 gctacctgag tcggacacga tgtatggttc ctggttgccg ggacggctgg gcctgtgtca
     3901 cagatgcaga gccagtccct cagtctaggc ctagaactgt ggtgcactgc tgcagctctt
     3961 ggacaccgtc tcctcggatt ctgcacacag gttggactct caatgtgaac ccaaagcttg
     4021 tctggctctc tgaaaacaac ttttgctctt taggttcttt acattgtaat aatgctgtat
     4081 ttaaacagaa tatttaaatg taatattaaa gaaatattga agagaa
//
