LOCUS       NM_139001               8050 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus chondroitin sulfate proteoglycan 4 (Cspg4), mRNA.
ACCESSION   NM_139001 NM_177105
VERSION     NM_139001.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8050)
  AUTHORS   Gobbo,D., Rieder,P., Fang,L.P., Buttigieg,E., Schablowski,M.,
            Damo,E., Bosche,N., Dallorto,E., May,P., Bai,X., Kirchhoff,F. and
            Scheller,A.
  TITLE     Genetic Downregulation of GABAB Receptors from Oligodendrocyte
            Precursor Cells Protects Against Demyelination in the Mouse Spinal
            Cord
  JOURNAL   Cells 13 (23), 2014 (2024)
   PUBMED   39682762
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8050)
  AUTHORS   Pivonkova,H., Sitnikov,S., Kamen,Y., Vanhaesebrouck,A., Matthey,M.,
            Spitzer,S.O., Ng,Y.T., Tao,C., de Faria,O. Jr., Varga,B.V. and
            Karadottir,R.T.
  TITLE     Heterogeneity in oligodendrocyte precursor cell proliferation is
            dynamic and driven by passive bioelectrical properties
  JOURNAL   Cell Rep 43 (11), 114873 (2024)
   PUBMED   39423130
REFERENCE   3  (bases 1 to 8050)
  AUTHORS   Do,L.N.H., Delgado,E., Lim,C.G., Bkhache,M., Peluzzo,A.M., Hua,Y.,
            Oza,M., Mohsin,S., Chen,H., Autieri,M.V., Kim,S. and Liu,X.
  TITLE     A neuro-lymphatic communication guides lymphatic development by
            CXCL12 and CXCR4 signaling
  JOURNAL   Development 151 (22) (2024)
   PUBMED   39470100
REFERENCE   4  (bases 1 to 8050)
  AUTHORS   Omura,S., Ogawa,R., Kawachi,T., Ogawa,A., Arai,Y., Takayama,N.,
            Masui,A., Kondo,K., Sugimoto,H., Shinohara,H.M., Takahashi,T.,
            Maeda,H. and Ohyama,K.
  TITLE     Olig2+/NG2+/BLBP+ astrocyte progenitors: a novel component of the
            neurovascular unit in the developing mouse hippocampus
  JOURNAL   Front Cell Neurosci 18, 1464402 (2024)
   PUBMED   39484182
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8050)
  AUTHORS   Madsen,S., Delgado,A.C., Cadilhac,C., Maillard,V., Battiston,F.,
            Igelbuscher,C.M., De Neck,S., Magrinelli,E., Jabaudon,D.,
            Telley,L., Doetsch,F. and Knobloch,M.
  TITLE     A fluorescent perilipin 2 knock-in mouse model reveals a high
            abundance of lipid droplets in the developing and adult brain
  JOURNAL   Nat Commun 15 (1), 5489 (2024)
   PUBMED   38942786
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8050)
  AUTHORS   Ozerdem,U., Grako,K.A., Dahlin-Huppe,K., Monosov,E. and
            Stallcup,W.B.
  TITLE     NG2 proteoglycan is expressed exclusively by mural cells during
            vascular morphogenesis
  JOURNAL   Dev Dyn 222 (2), 218-227 (2001)
   PUBMED   11668599
REFERENCE   7  (bases 1 to 8050)
  AUTHORS   Diers-Fenger,M., Kirchhoff,F., Kettenmann,H., Levine,J.M. and
            Trotter,J.
  TITLE     AN2/NG2 protein-expressing glial progenitor cells in the murine
            CNS: isolation, differentiation, and association with radial glia
  JOURNAL   Glia 34 (3), 213-228 (2001)
   PUBMED   11329183
REFERENCE   8  (bases 1 to 8050)
  AUTHORS   Schneider,S., Bosse,F., D'Urso,D., Muller,H., Sereda,M.W., Nave,K.,
            Niehaus,A., Kempf,T., Schnolzer,M. and Trotter,J.
  TITLE     The AN2 protein is a novel marker for the Schwann cell lineage
            expressed by immature and nonmyelinating Schwann cells
  JOURNAL   J Neurosci 21 (3), 920-933 (2001)
   PUBMED   11157078
REFERENCE   9  (bases 1 to 8050)
  AUTHORS   Niehaus,A., Stegmuller,J., Diers-Fenger,M. and Trotter,J.
  TITLE     Cell-surface glycoprotein of oligodendrocyte progenitors involved
            in migration
  JOURNAL   J Neurosci 19 (12), 4948-4961 (1999)
   PUBMED   10366628
REFERENCE   10 (bases 1 to 8050)
  AUTHORS   Grako,K.A., Ochiya,T., Barritt,D., Nishiyama,A. and Stallcup,W.B.
  TITLE     PDGF (alpha)-receptor is unresponsive to PDGF-AA in aortic smooth
            muscle cells from the NG2 knockout mouse
  JOURNAL   J Cell Sci 112 (Pt 6), 905-915 (1999)
   PUBMED   10036240
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK052394.1, AF352400.1, AK220559.1, AK140986.1 and AC126257.4.
            
            On May 4, 2007 this sequence version replaced NM_139001.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript from the same
            strain was available for the full length of the gene. The extent of
            this transcript is supported by orthologous human data.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF352400.1, SRR11927938.3048701.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-193               AK052394.1         73-265
            194-208             AF352400.1         138-152
            209-4036            AK052394.1         281-4108
            4037-5051           AK220559.1         958-1972
            5052-6446           AK140986.1         460-1854
            6447-8050           AC126257.4         113828-115431
FEATURES             Location/Qualifiers
     source          1..8050
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 30.32 cM"
     gene            1..8050
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /note="chondroitin sulfate proteoglycan 4"
                     /db_xref="GeneID:121021"
                     /db_xref="MGI:MGI:2153093"
     exon            1..174
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..7070
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /note="nerve/glial antigen 2; AN2 proteoglycan;
                     chondroitin sulfate proteoglycan NG2; proteoglycan AN2;
                     AN2/NG2 proteoglycan"
                     /codon_start=1
                     /product="chondroitin sulfate proteoglycan 4 precursor"
                     /protein_id="NP_620570.2"
                     /db_xref="CCDS:CCDS23211.1"
                     /db_xref="GeneID:121021"
                     /db_xref="MGI:MGI:2153093"
                     /translation="MLLGPGHPLSAPALALALTLALLVRSTAPASFFGENHLEVPVPS
                     ALTRVDLLLQFSTSQPEALLLLAAGQDDHLLLQLHSGCLQVRLALGQKELKLQTPADT
                     VLSDSAPHTVVLTVSDSWAVLSVDGVLNTSAPIPRASHLKATYGLFVGSSGSLDLPYL
                     KGISRPLRGCLHSAILNGRNLLRPLTSDVHEGCAEEFSAGDEVGLGFSGPHSLAAFPA
                     WSTREEGTLEFTLTTRSQQAPLAFQAGDKRGNFIYVDIFEGHLRAVVEKGQGTMLLRN
                     SVPVADGQPHEVSVHIDVHRLEISVDQYPTRTFNRGVLSYLEPRGSLLLGGLDTEASR
                     HLQEHRLGLAPGAANISLVGCIEDFSVNGRRQGLRDAWLTRDMSAGCRPEEDEYEEEV
                     YGPYETFSTLAPEAWPAMELPEPCIPEPGLPAVFANFTQLLTISPLVVAEGGTAWLEW
                     RHVQPTLDLTEAELRKSQVLFSVSQSARHGDLELDILGAQTRKMFTLLDVVNRKARFV
                     HDGSEDTSDQLMLEVSVTARAPVPSCLRRGQIYILPIQVNPVNDPPRIIFPHGSLMVI
                     LEHTQKPLGPEIFQAYDPDSACEGLTFQLLGVSSGVPVEHRDQPGEPATEFSCRELEV
                     GDIVYVHRGGPAQDLTFRVSDGMQASAPATLKVVAVRPAIQILHNTGLHLAQGSAAAI
                     LPANLSVETNAVGQDVSVLFRVTGTLQFGELQKQGAGGVEGTEWWDTLAFHQRDVEQG
                     RVRYLSTDPQHHTQDTVEDLILEVQVGQETLSNLSFPVTIQRATVWMLRLEPLHTQNP
                     HQETLTPAHLEASLEEEEEEGSPQPHTFHYELVQAPRRGNLLLQGTRLSDGESFSQSD
                     LQAGRVTYRATMRTSEAADDSFRFRVTSPPHFSPLYTFPIHIGGDPNAPVLTNVLLMV
                     PEGGEGVLSADHLFVKSLNSASYLYEVMEQPHHGKLAWRDPKGKSTPVTSFTNEDLLH
                     GRLVYQHDDSETIEDDIPFVATRQGEGSGDMAWEEVRGVFRVAIQPVNDHAPVQTISR
                     VFHVARGGQRLLTTDDVAFSDADSGFSDAQLVLTRKDLLFGSIVAMEEPTRPIYRFTQ
                     EDLRKKQVLFVHSGADHGWLQLQVSDGQHQATAMLEVQASEPYLHVANSSSLVVPQGG
                     QGTIDTAVLQLDTNLDIRSGNEVHYHVTAGPQWGQLLRDGQSVTSFSQRDLLDGAILY
                     SHNGSLSPQDTLAFSVAAGPVHTNTFLQVTIALEGPLAPLQLVQHKKIYVFQGEAAEI
                     RRDQLEVVQEAVLPADIMFSLRSPPNAGYLVMVSHGASAEEPPSLDPVQSFSQEAVNS
                     GRVLYLHSRPGAWSDSFSLDVASGLGDPLEGISVELEVLPTVIPLDVQNFSVPEGGTR
                     TLAPPLVQITGPYFPTLPGLVLQVLEPPQHGALQKEDHSQDGSLSTFSWREVEEQLIR
                     YVHDGSETQTDAFVLLANASEMDRQSQPVAFTITILPVNDQPPVLTTNTGLQIWEGAI
                     VPIPPEALRGTDNDSGPEDLVYTIEQPSNGRIALRVAPDTEVHRFTQAQLDSGLVLFS
                     HRGALEGGFHFDLSDGAHTSPGHFFRVVAQKQALLSLEGTRKLTVCPESVQPLSSQSL
                     SASSSTGADPRHLLYRVVRGPQLGRLLHAQQGSAEEVLVNFTQAEVNAGNILYEHEMS
                     SEPFWEAHDTIGLLLSSPPARDLAATLAVMVSFDAACPQRPSRLWKNKGLWVPEGQRA
                     KITVAALDAANLLASVPASQRSRHDVLFQVTQFPTRGQLLVSEEPLHARRPYFLQSEL
                     AAGQLVYAHGGGGTQQDGFRFRAHLQGPTGTSVAGPQTSEAFVITVRDVNERPPQPQA
                     SIPLRVTRGSRAPVSRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLAGDNTGPVTHFT
                     QADVDAGRLAFVANGSSVAGVFQLSMSDGASPPIPMSLAVDVLPSTIEVQLRAPLEVP
                     QALGRTSLSRQQLQVISDREEPDVAYRLTQGPLYGQLLVGGQPASAFSQLQVDQGDVV
                     FVFTNFSSSQDHFKVVALARGVNASATVNVTVQALLHVWAGGPWPQGTTLRLDPTVLD
                     ASELANRTGSMPHFRLLAGPRYGRVVRVSQGRTESRSNQLVEHFTQRDLEEGQLGLEV
                     GKPEGRSTGPAGDRLTLELWAKGVPPAVALLDFATEPYHAAKSYSVALLSVPEAVRTE
                     TEKPGRSVPTGQPGQAASSPVPTAAKGGFLGFLEANMFSIIIPVCLILLLLALILPLL
                     FYLRKRNKTGKHDVQVLTAKPRNGLAGDTETFRKVEPGQAIPLITVPGQGPPPGGQPD
                     PELLQFCRTPNPALRNGQYWV"
     exon            175..338
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     exon            339..3890
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     exon            3891..4373
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     exon            4374..4550
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     exon            4551..4749
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     exon            4750..4884
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     exon            4885..5051
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     exon            5052..5235
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     exon            5236..8050
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8019..8024
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /note="hexamer: AATAAA"
     polyA_site      8030
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /note="major polyA site"
     regulatory      8037..8042
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /note="hexamer: AATAAA"
     polyA_site      8038
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /note="major polyA site"
     polyA_site      8050
                     /gene="Cspg4"
                     /gene_synonym="4732461B14Rik; AN2; Cspg4a; NG2"
                     /note="major polyA site"
ORIGIN      
        1 gacttgcgac ttgcgactcg gtgctgtcca gattcagcac gctctgttcc ttcgccttac
       61 aagtccaggc acccagcccc gccgcgatgc ttctcggccc gggacacccg ctgtcagctc
      121 cagccctggc cttggctctt accttggcct tgttggtcag atctacagct cctgcctcct
      181 tcttcgggga gaaccacctg gaggtgcccg tgccctcagc tctgaccaga gtagacctgc
      241 tgctccagtt ctccacatcc cagcccgaag ccctgctcct cttggcagca ggccaagatg
      301 accatctctt gctccagctc cactcaggat gcctccaggt cagacttgcc ctgggacaga
      361 aggagctaaa gctgcagacg ccagcagaca ccgtgctgag tgactctgcc ccccacactg
      421 tagtgctcac tgtctccgac agctgggctg tgctgtctgt tgacggagtg ttgaacacct
      481 ctgctcccat cccaagagca tcccacctca aggccaccta cgggctcttc gtgggctcct
      541 ctggaagcct tgacctgcct tacctgaagg gaatcagccg acccctaagg ggctgcctcc
      601 actcagccat tctcaatggc cgcaacctcc tccgtccgct gacctccgat gttcatgaag
      661 gttgtgctga agaattctct gctggtgatg aagtgggcct gggcttctct gggccccact
      721 cactggctgc cttccctgcc tggagcactc gggaggaagg caccctggag tttacgctca
      781 ccactcggag tcagcaagca cccctggcct tccaagcagg ggacaagcgt ggcaacttta
      841 tctacgtgga catatttgag ggccacttgc gggctgtggt tgagaaaggc caaggtacca
      901 tgctactccg caacagcgtg cctgtggctg atgggcagcc ccacgaggtc agcgtacaca
      961 tagatgttca ccggctggaa atctctgtag accaataccc tacgcgtact ttcaaccgtg
     1021 gggtcctcag ctacctggag ccacgtggca gtctcctcct tgggggtctg gacacagaag
     1081 cctctcgcca cctccaagag caccgtctgg gcctggcacc gggggctgcc aatatctccc
     1141 tggtaggctg catagaagat ttcagtgtta atggcaggag gcagggcctc cgggatgcct
     1201 ggctgacccg tgacatgtca gcaggatgca ggcctgagga ggatgaatat gaagaagagg
     1261 tctatggccc atatgaaact ttctccaccc tggcaccaga agcttggcca gccatggaac
     1321 tgccagagcc atgtattcct gagccgggac tgcctgctgt ctttgcaaac ttcacccagc
     1381 tgcttaccat cagccccctg gtggtggccg agggtggcac ggcctggctt gagtggcggc
     1441 acgtgcagcc caccctggac ctgacagagg cagagctgcg caagtcccag gtgctgttca
     1501 gcgtgagcca gagtgcacga catggtgacc tggagctaga catcctggga gcccaaaccc
     1561 ggaaaatgtt taccctgttg gacgtggtga accgtaaggc ccgctttgtt cacgatggct
     1621 ctgaagacac ctctgaccag ctgatgctgg aggtgtctgt gactgctcgg gcacctgtgc
     1681 cctcctgcct gcggaggggc caaatttaca tcctgcccat ccaggtcaat cctgtcaacg
     1741 atccacctcg catcatcttc ccccacggca gcctcatggt gatcctggaa cacacacaga
     1801 agcctctggg accggagatt ttccaggcct acgacccgga ctctgcctgt gagggtctca
     1861 ccttccagct ccttggcgtc tcctctggtg tccctgtgga acaccgagac cagccaggag
     1921 agccagcaac tgagttttcc tgtcgggaac tggaggtggg cgacatagtc tatgtccacc
     1981 gtggtgggcc tgcacaggac ctaacattcc gggtcagtga tgggatgcag gccagtgctc
     2041 cagcgacact gaaggtagtg gccgtccggc cagccataca gatcctccac aacacagggc
     2101 tgcacctggc ccagggctct gccgcagcca tcttgcctgc caacctgtca gtagaaacga
     2161 acgcggtggg acaggatgtg agcgtgctgt tccgagtcac tggtaccttg caattcgggg
     2221 agctgcagaa gcagggggcc ggaggggtcg agggcaccga gtggtgggac acactggcct
     2281 tccaccagcg cgatgtggag caaggccgag tgaggtacct gagcactgac ccacagcacc
     2341 acacccaaga cacagtggag gacctgatct tagaggtgca ggtgggccag gagacactga
     2401 gcaatctgtc tttcccagtg accatccaga gggccacagt atggatgctg aggcttgaac
     2461 ctctgcatac acagaaccct catcaggaga ccctcacccc agcccaccta gaggcatccc
     2521 tggaggaaga ggaggaagag ggaagcccac aacctcatac cttccactat gagttggttc
     2581 aggcccccag aagaggcaac ctcctgcttc agggtacaag gctgtcagac ggcgagagct
     2641 tcagccagag tgacctgcag gccggtcggg tgacctacag ggccacaatg cggacctctg
     2701 aggcagccga tgactccttc cgtttccggg tcacatcccc accccatttc tccccgctct
     2761 acacattccc catccacatt ggtggtgacc caaatgctcc cgtcctcact aacgtccttc
     2821 tcatggtccc cgagggaggg gagggcgtgc tgtctgccga ccacctcttc gtcaagagtc
     2881 tcaacagcgc cagctatctc tatgaggtga tggagcagcc tcaccatggc aagttggctt
     2941 ggagggaccc aaaggggaag tccaccccag tgacatcctt cactaatgag gacctacttc
     3001 atggccgact ggtctaccag cacgatgact ctgagaccat agaggatgat atcccgtttg
     3061 tggccacacg ccagggagag ggcagtggtg acatggcctg ggaggaggtg cgtggtgtct
     3121 tccgagtggc catccagcct gtgaatgacc acgcccctgt gcagaccatt agccgtgtct
     3181 tccacgtggc ccggggtgga cagcgactgc tgactacaga tgatgtagcc ttcagcgatg
     3241 ctgattcagg gttcagtgat gcgcaactgg tgctgacccg caaggacctc ctctttggca
     3301 gcattgtggc tatggaggag cccacgaggc ccatctaccg gttcacccaa gaggatctca
     3361 ggaagaagca agtcctgttt gtgcactcgg gggccgacca cggctggctc cagctgcagg
     3421 tgtctgatgg gcagcaccag gctactgcca tgctggaggt ccaagcctca gaaccctatc
     3481 ttcacgtagc caatagttct agtctcgtgg ttcctcaagg aggccagggc accattgaca
     3541 ctgctgtgct ccagctggac accaacctgg acatacgaag tggaaatgag gtccactacc
     3601 atgtaaccgc tggtcctcag tgggggcagc tgctccggga tggccagtca gtcacctcct
     3661 tctcccaacg ggacttgctc gatggggcca tcctctacag ccacaatggc agcctcagcc
     3721 cccaagacac cctggcgttt tctgtggcag cagggccagt acacactaac accttcctac
     3781 aagtgaccat tgccctcgag ggtcccctgg ccccactgca actggtgcag cacaaaaaga
     3841 tctacgtctt ccagggggaa gcggctgaga tcagaaggga ccagctagag gtggtccagg
     3901 aggcagtgct gcctgccgac atcatgttct cgttgagaag ccccccgaac gccggctacc
     3961 tggtgatggt gtcccacggc gcttcagcag aggagccgcc cagcctggac cctgtgcaga
     4021 gcttctccca ggaggcagtg aattcaggcc gggttctcta cctgcactct cgccctggag
     4081 cctggagtga ttccttctcc ctggatgtgg cctcgggcct gggtgatcct cttgaaggca
     4141 tctctgtgga gctggaggtg ctgcccacag tcatccccct ggatgttcaa aacttcagcg
     4201 ttcccgaggg cggcacccgg acgctggccc ctcctctggt ccagatcact gggccttact
     4261 tccccacgct gccaggcctt gtcctgcagg tgctagagcc accgcagcac ggggccctgc
     4321 agaaggagga tcattctcaa gatgggagcc tcagcacctt ctcctggaga gaggtggaag
     4381 agcagctgat ccgctacgtg catgatggaa gtgagacaca gacagacgcc tttgttctgc
     4441 tagctaatgc ctcagagatg gaccgccaga gccagcccgt ggccttcacg atcaccatcc
     4501 ttcctgttaa tgaccaaccc cctgttctca ccacaaacac aggcctgcaa atctgggagg
     4561 gggccattgt gcccatccct cctgaggccc tcaggggaac agacaatgat tcgggcccag
     4621 aagacttggt ctacaccatc gagcagccca gcaacggacg gatcgccttg agggtggcac
     4681 cagacaccga ggtccaccgc ttcacacagg cccagctgga cagtgggctt gtgctgttct
     4741 cacacagagg agccctggaa ggaggcttcc acttcgacct ctctgacggc gcacacactt
     4801 ctcctggaca tttcttccga gtggtggccc agaagcaggc actcctctcc ttggagggca
     4861 cccggaagtt gaccgtctgt ccagagtctg tgcagccgct cagcagccag agcctgagcg
     4921 ccagttccag cacaggcgct gaccctcgtc acctgctcta ccgggtggta agaggccccc
     4981 agcttggccg actcctccat gcccagcaag gaagtgcaga ggaggtcttg gtgaacttca
     5041 cccaggctga ggtaaatgct gggaatattc tgtatgagca cgagatgtcc tctgagccct
     5101 tctgggaagc ccatgacacc atcggtctcc tactgtcctc accacctgcc agggatctgg
     5161 ctgccaccct ggccgtgatg gtgtctttcg atgctgcctg tccccagcgc cccagccgtc
     5221 tctggaagaa caaaggtctt tgggtccccg agggccagcg ggccaagatc actgtggctg
     5281 cccttgatgc cgccaacctc ctagccagtg tgccagcatc tcagcgcagt cggcatgatg
     5341 tactcttcca ggtcacacag ttccccaccc gaggccagct cctggtgtct gaggagccac
     5401 tccatgccag gaggccctac ttcctgcaat ctgagctggc cgcgggacag ctggtgtacg
     5461 cccatggtgg tgggggcacg cagcaggatg gcttccgctt ccgtgcccac ctccagggac
     5521 cgacggggac ttctgtggca ggaccccaga cctctgaggc ctttgtcatc actgtgaggg
     5581 acgtgaatga gcggccccct cagccacagg cctccattcc tctccgtgtc accaggggct
     5641 cacgagcccc tgtatctcga gcccagctga gtgtagtcga cccagactca gctccagggg
     5701 aaattgaata tgaagtacag agggcacccc acaatggctt cctgagcctg gctggggaca
     5761 acactggacc tgtgactcac ttcacacagg ctgatgtgga tgcagggcga ctggccttcg
     5821 tggcaaatgg gagcagtgtg gccggcgtct tccagttgag catgtctgat ggagccagcc
     5881 cccccatacc catgtccctg gctgtggatg tcttgccatc caccattgag gtgcagctgc
     5941 gtgcacccct ggaggtgccc caagctctag gacgtacctc actgagccgg cagcagcttc
     6001 aggttatttc cgatcgtgag gaaccagatg tagcttaccg cctcactcag gggcccctgt
     6061 atgggcagct actagtaggg gggcagcctg cctccgcctt cagccagctg caggtagacc
     6121 agggggacgt ggtctttgtc ttcaccaact tctcttcctc tcaggatcac ttcaaagttg
     6181 tagctctggc caggggtgtg aacgcatcag ccaccgtaaa tgtcacagtg caggctctgt
     6241 tgcatgtgtg ggctggtggg ccatggcctc agggtaccac cctgcgcctt gaccccactg
     6301 tgctcgatgc cagtgagctg gccaaccgca caggcagtat gccccacttc cggctcctgg
     6361 caggaccccg ctatggccgt gtggtccgag tgtcccaagg ccgaacagaa tctaggagca
     6421 accaacttgt ggaacatttc actcagcggg acctggaaga gggacagctg gggctagagg
     6481 tgggcaagcc agagggcagg tccactggcc cagcaggtga cagacttact ctggagctgt
     6541 gggcaaaggg tgtcccacct gctgtggcct tgctggactt tgccactgag ccttaccatg
     6601 cggccaaatc ctacagtgtg gccctactca gtgtccctga ggctgttcgt acagaaacag
     6661 agaaaccagg aagaagcgtc cccactggcc agccaggcca ggcagcatcc agccccgtgc
     6721 ccactgcggc caaaggtggt ttcctgggct tcttagaggc caacatgttc agcatcatca
     6781 ttccggtgtg cctgatcctc ctgctcctgg cccttatctt gcctctgctc ttctacctcc
     6841 gcaaacgcaa caagacgggc aagcacgatg tccaggtgtt gaccgccaaa ccccgcaatg
     6901 gcctagccgg tgacacagag acctttcgaa aggtagagcc aggccaagct attccactca
     6961 taactgtgcc tggccagggg cccccaccag gaggccagcc tgacccagaa ctattgcagt
     7021 tttgccggac acccaatcct gccctcagga atggccagta ctgggtgtga gacctggcct
     7081 gtaccagatg ctgcccaccc atccaccagg cccactgttg ctgtaccctg gtctggcctg
     7141 aggatctcca gagccaaaaa aaaaaaaaag accttgagat gccaggggtg gagggagctg
     7201 ggagacagct ggaatgagtg gggtcaagag ctggagactt cctcggctct cttagacctg
     7261 gagcgccatg gggccaaggt gagaggcagc taaagtcagc tcactgcaga aaacaggaaa
     7321 gcatcctaga tgggtcacaa ctccgggtcc tggaactgtg accttagata aatcctgacc
     7381 cagactgcca aggtcagggg aacgagagca ccctctctgg tgttttcctg aagccgaatg
     7441 gggaggaatg ttaggcaata gattaatata ttcaaggtgc aagatgggtg gggttgctct
     7501 ggggttggtt aatttaaggc aagaaagcta tttaacatgg tgctggccta gccaggcctg
     7561 atgaagccct ggagtacacg ggatagacaa aggtctgaag tcatgtcacc cacaaagccc
     7621 tgtggtggag cgcccgaagc actggccagc aactgtcagt gcttggactg ggagtgttag
     7681 aggccaccct ggtggccatg ctctcctcaa gactagggag caggcaaacg aagacacttg
     7741 actccactga gccgtggcga atggtgcttc ggaggctccg agcagctgtg cgtcgtttga
     7801 gtttgtgcac tgggctccta tccgtggcag cttcactccc ctggggcagg ccatgtggcc
     7861 tcgcttcatg gggggtgggg atggacaaat ctggacaagc tcttgaattt ccacctcctg
     7921 gggcattccc aaagtcctct actctcacct gtacaggcag atgggctgtt tgttgagatg
     7981 ggaccaaagc ccttacgcta cagggaacgt cagggaaaaa taaaaataaa taaataaata
     8041 aatgctccca
//
