LOCUS       NM_152809               4394 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus casein kinase 1, gamma 3 (Csnk1g3), mRNA.
ACCESSION   NM_152809 NM_177174
VERSION     NM_152809.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4394)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4394)
  AUTHORS   Lee,S.Y., Kim,H., Li,C.M., Kang,J., Najafov,A., Jung,M., Kang,S.,
            Wang,S., Yuan,J. and Jung,Y.K.
  TITLE     Casein kinase-1gamma1 and 3 stimulate tumor necrosis factor-induced
            necroptosis through RIPK3
  JOURNAL   Cell Death Dis 10 (12), 923 (2019)
   PUBMED   31801942
  REMARK    GeneRIF: Casein kinase-1gamma1 and 3 stimulate tumor necrosis
            factor-induced necroptosis through RIPK3.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4394)
  AUTHORS   Nakano,Y., Wiechert,S. and Banfi,B.
  TITLE     Overlapping Activities of Two Neuronal Splicing Factors Switch the
            GABA Effect from Excitatory to Inhibitory by Regulating REST
  JOURNAL   Cell Rep 27 (3), 860-871 (2019)
   PUBMED   30995482
REFERENCE   4  (bases 1 to 4394)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4394)
  AUTHORS   Trivedi,C.M., Zhu,W., Wang,Q., Jia,C., Kee,H.J., Li,L.,
            Hannenhalli,S. and Epstein,J.A.
  TITLE     Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic
            cardiac myocyte proliferation
  JOURNAL   Dev Cell 19 (3), 450-459 (2010)
   PUBMED   20833366
REFERENCE   6  (bases 1 to 4394)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   7  (bases 1 to 4394)
  AUTHORS   Verlaet,M., Deregowski,V., Denis,G., Humblet,C., Stalmans,M.T.,
            Bours,V., Castronovo,V., Boniver,J. and Defresne,M.P.
  TITLE     Genetic imbalances in preleukemic thymuses
  JOURNAL   Biochem Biophys Res Commun 283 (1), 12-18 (2001)
   PUBMED   11322760
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK049379.1, BY729947.1, CN454971.1, BQ443928.1, AK032675.1,
            AK034842.1 and AK163441.1.
            
            On or before Aug 30, 2006 this sequence version replaced
            NM_177174.2, NM_152809.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849375,
                              SAMN00849380 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-123               AK049379.1         2-124
            124-517             BY729947.1         101-494
            518-1199            CN454971.1         1-682
            1200-1679           BQ443928.1         234-713
            1680-2232           AK032675.1         235-787
            2233-4241           AK034842.1         414-2422
            4242-4394           AK163441.1         489-641
FEATURES             Location/Qualifiers
     source          1..4394
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 29.1 cM"
     gene            1..4394
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /note="casein kinase 1, gamma 3"
                     /db_xref="GeneID:70425"
                     /db_xref="MGI:MGI:1917675"
     exon            1..488
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            489..912
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             735..2009
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /EC_number="2.7.11.1"
                     /note="CKI-gamma 3"
                     /codon_start=1
                     /product="casein kinase I isoform gamma-3"
                     /protein_id="NP_690022.2"
                     /db_xref="CCDS:CCDS37823.1"
                     /db_xref="GeneID:70425"
                     /db_xref="MGI:MGI:1917675"
                     /translation="MDNKKKDKDKSDDRMARPSGRSGHSTRGTGSSSSGVLMVGPNFR
                     VGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQV
                     YYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIY
                     RDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSI
                     NTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL
                     CENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTP
                     VGAVQQDPALSSNREAHQHRDKIQQSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEV
                     EVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK"
     exon            913..953
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1023
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1172
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1407
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1493
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1578
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1579..1727
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1728..1823
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1824..1930
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1931..1954
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1955..4394
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2446..2451
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2471
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /note="major polyA site"
     regulatory      4265..4270
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4285
                     /gene="Csnk1g3"
                     /gene_synonym="3300002K07Rik; C330049O21Rik"
                     /note="major polyA site"
ORIGIN      
        1 cttttcgctg atgcgggctg cttgggagcc tccgccgccg gagagactag acgctttcct
       61 ttctttttat tattattttt ttctctccac cccctctttt cttcctttct tttttttttt
      121 tttcctcctc tcatgtgttc acttccgggt ccggtgccgc tccggatgct cgaggccgaa
      181 ggatgtttga cctccggata agcgaggcgc cgccgtgcat tcattcccgg ttgcctcggt
      241 ggccacagcc gcggcccgga cggcgactcg gtgctcagcg gcggcagtag gaggcgccgg
      301 cggcggcggt ggtggcggcg gcggcgcgcg gagccagtag acgcgggggc ccccgtcctt
      361 ccctcgctcg cgccttcctt ccccggcctc gttcatcttc cgcggccgcc ggcggcgggg
      421 atgtgccggc gctgacgggc ggacgcgcgc gccgggccga acccgctgcc cgcggccgcg
      481 cctttgagct ctctatcaac agcagcttac atcactgaga agataatttt gaagacatac
      541 tttgctgaga agacaactga gaagctgtac gaatgggatg aacaggcgtc acttgactga
      601 ctatccgctg acgtttgagt gctagcgttg ctcatagggt actgctacct agtgatgcac
      661 ctgctcttac agtaccccat ttcatcgtgc ttgtcttgat taaagaattc aaagtggagt
      721 accgcaaact tgatatggat aataaaaaga aagacaagga caaatcagat gatagaatgg
      781 cacggcccag tggtcggtca gggcacagca ctcgaggaac tgggtcttct tcatctggag
      841 ttttaatggt tggacctaac tttagagttg ggaaaaaaat cggatgtggc aattttggag
      901 aattacgatt agggaaaaat ttatacacaa atgaatatgt ggcgattaaa ctggagccca
      961 tgaaatccag agcaccacag ctgcatttgg aatacagatt ctataagcag ttaggatctg
     1021 gagatggtat acctcaagtt tactattttg gcccttgtgg taaatacaac gcgatggtgc
     1081 tggaactgct gggaccgagt ttggaggatt tgtttgacct ctgtgataga acattttctc
     1141 ttaaaacagt tctcatgata gctatacagc tgatttctcg tatggagtat gtccactcaa
     1201 agaacttgat atacagagat gtgaagcctg agaacttctt aataggacgg ccaggaaaca
     1261 aagcccagca agtcattcat atcatagatt ttggtttggc aaaggaatat attgatccag
     1321 agacaaagaa acatatacca tacagagaac acaaaagcct taccggaacc gccagataca
     1381 tgagcataaa cacacatcta ggaaaagagc agagtagaag agatgattta gaagccttag
     1441 gccacatgtt catgtacttc ctgagaggca gtcttccttg gcaaggctta aaggctgaca
     1501 cattaaaaga gaggtatcag aaaattggag acacaaaacg agccacacca atagaagtgt
     1561 tgtgtgagaa cttcccagaa gaaatggcaa cgtatctccg ttacgtacga aggctggatt
     1621 tttttgaaaa gccagactat gattacctaa gaaagctttt tactgacttg tttgatcgaa
     1681 aagggtatat gtttgattat gaatatgact ggattggtaa acagttgcct actccagtag
     1741 gtgcagttca gcaagaccct gctctgtcat caaacagaga agcacaccaa cacagagata
     1801 agatacagca gtctaaaaac caggttgtaa gttctacaaa tggagagctg aacacggatg
     1861 accccacggc aggacggtcg aatgcaccca ttacagctcc tacagaagtg gaagtgatgg
     1921 acgagacaaa ctgccagaaa gtattgaata tgtggtgctg ctgttttttc aaacgaagga
     1981 aaaggaaaac catacaacgt cacaaatgac tggacacaga cagatcctgg ggagttactt
     2041 acatgttcat atgctgtctc gtgattaaaa tcatctctgt agtgaccaca tatattttca
     2101 aggactcact cttgaaacaa aaatgtcata ctttcatatt tcattttgtg attgtcttac
     2161 attcattccc cccaccctta atttaacttt atggaagctt taagattttg tcaaaacacg
     2221 agtgctttgc ccatcattga attgaatgga ccaatgaagt ggtattgatg aacacagttc
     2281 cataggacat ttttcagagg ctcttctgtt ctagaaaaca atacaggtgt ccaaatatca
     2341 attaattgta cctaatttga tttctttatg ttttctataa aagcataatc aaacaggaat
     2401 tttcttccca ctggatagtg cagcagagaa aacagttgcc caaatattaa aaacaacttt
     2461 cttgaacagt tcctgttttg tggcatctgc attgatttca gtatgactga tggtactgtt
     2521 attcgtgaat catattgaca ttctctctgt gaaatcatgg tacagtcact gcccagaggt
     2581 actgaggaaa atgtactatg ggattggcaa acggtggcgg taaataatca gcagttgttg
     2641 gcaatgcgag ctcggcttct gtggcgccac tgtgtgaagt gcagctgcag aagaagcagg
     2701 agcgccagga acgtttgttt aatgtcactc tctgcttcca gatgataata tatactagat
     2761 ggcaagaaat gagtcctgga gaagtaatgt atgggagagt ttaaaaaaca cactaaggaa
     2821 aggatgacaa tgtgaaactt gtttcagtgt gtaaggctgg agccccttaa gagcctactg
     2881 ccccgtggcc acatttctct cagaagcaga aacccgagga cgtgccatag agtggtggct
     2941 gcctgtgatg cctctcttca gatgcagaaa agagtcctac tcccagcaat aagcaccggg
     3001 tcactctgtt gccctctgtg cacactagtc tcgtgtgttc agctttgcta gttctctgac
     3061 atttcctgtc ttgagcataa taatgtggct gattggagaa tgttctggag agggtgggct
     3121 gggtgcgttg cctccatagc tttcacagtg cctgcatatg cacagcgtaa cagttctgtt
     3181 atgcgccaag tccatcccac tttgcaagtg tgctctgttt tacgccatga ggacacaggc
     3241 atagtttgtg tctcatcctg tcagccgggt ggtcgagagt taaaaaggct ggccagacag
     3301 atgctgttga tcatatcaca cattcgtctt ctacttagaa acccgtcgct cctcctccct
     3361 gcgctctcct ctctgtctta agtgtgagcc ttcaggtatg cttatttatt ttttttgtct
     3421 caaggtaaca tttaaaatat gtattaaagg aaatgaatcc acattttttt acttccttat
     3481 tgaatttaca ggtatttaat tgtattttgt aatttatttt tcttattagc caaaagttca
     3541 atgtgttgtt tttgataaat tgggcgccca catgaacatc ccaggtcagg acatcgttta
     3601 tctttatttt tgattttaaa gacctacact caactgagaa aatatttgct gtataatttg
     3661 atcaacagtt tccattctct ttgtatactg tcatgatatc taaactgcag gagttaaata
     3721 ctgagttttt tattttgttt gctctgagca aggtagatgg atattttggc catttataat
     3781 gtgaaaccac ttctttacag tatttgacca aatttgtgtg tctatgatat ttgtaaatac
     3841 atgcgatatc tgtatttctt atcataaacc tatttagttt tattctcagt agggtttttg
     3901 gactgtacag tgtttatatg atctgaactc cttatacata agaaggtgtg tatattaatc
     3961 caattatgga cttaaatatt ttaaaagtat gaataccctt atttgctgca aaggccagtg
     4021 tgtagacatt tgctttttag caatattttt aagtgctccg ttttcgtgct ggagaagaag
     4081 tctttggcac acagactggt cagtaatagg tgatgcaggt atgtccaggt taagccaaca
     4141 atgttttgca tttctatgct tcttttctgt caacactaat gaaatcaaca ttgcctgaat
     4201 gtctgaatac tgaaacacag ccctgtttaa aagtatgtaa ctgaaaaaaa aaaaaaaaga
     4261 aataaataaa ggtagttttt ttaaactcgc tctttcccct ttcctctaac catgagtgaa
     4321 ctaatgtttt tcattgctgc acagagcttt aaaaatgaac ttctgttcgt ttactactta
     4381 ctctaagagg cagg
//
