LOCUS       NM_007780               4776 bp    mRNA    linear   ROD 28-MAY-2024
DEFINITION  Mus musculus colony stimulating factor 2 receptor, beta,
            low-affinity (granulocyte-macrophage) (Csf2rb), transcript variant
            2, mRNA.
ACCESSION   NM_007780
VERSION     NM_007780.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4776)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4776)
  AUTHORS   Palani,S., Uddin,M.B., McKelvey,M., Shao,S. and Sun,K.
  TITLE     Immune predisposition drives susceptibility to pneumococcal
            pneumonia after mild influenza A virus infection in mice
  JOURNAL   Front Immunol 14, 1272920 (2023)
   PUBMED   37771584
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4776)
  AUTHORS   Forde,A.J., Kolter,J., Zwicky,P., Baasch,S., Lohrmann,F.,
            Eckert,M., Gres,V., Lagies,S., Gorka,O., Rambold,A.S.,
            Buescher,J.M., Kammerer,B., Lachmann,N., Prinz,M., Gross,O.,
            Pearce,E.J., Becher,B. and Henneke,P.
  TITLE     Metabolic rewiring tunes dermal macrophages in staphylococcal skin
            infection
  JOURNAL   Sci Immunol 8 (86), eadg3517 (2023)
   PUBMED   37566679
REFERENCE   4  (bases 1 to 4776)
  AUTHORS   Benard,A., Mittelstadt,A., Klosch,B., Glanz,K., Muller,J.,
            Schoen,J., Nuse,B., Brunner,M., Naschberger,E., Sturzl,M.,
            Mattner,J., Munoz,L.E., Sohn,K., Grutzmann,R. and Weber,G.F.
  TITLE     IL-3 orchestrates ulcerative colitis pathogenesis by controlling
            the development and the recruitment of splenic reservoir
            neutrophils
  JOURNAL   Cell Rep 42 (6), 112637 (2023)
   PUBMED   37300834
REFERENCE   5  (bases 1 to 4776)
  AUTHORS   Qi,T., Xu,X., Guo,Y., Xia,Y., Peng,L., Li,C., Ding,F., Gao,C.,
            Fan,M., Yu,M., Zhao,H., He,Y., Li,W., Hai,C., Gao,E., Zhang,X.,
            Gao,F., Fan,Y., Yan,W. and Tao,L.
  TITLE     CSF2RB overexpression promotes the protective effects of
            mesenchymal stromal cells against ischemic heart injury
  JOURNAL   Theranostics 13 (6), 1759-1773 (2023)
   PUBMED   37064880
  REMARK    GeneRIF: CSF2RB overexpression promotes the protective effects of
            mesenchymal stromal cells against ischemic heart injury.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4776)
  AUTHORS   Liboi,E., Jubinsky,P., Andrews,N.C., Nathan,D.G. and
            Mathey-Prevot,B.
  TITLE     Enhanced expression of interleukin-3 and granulocyte-macrophage
            colony-stimulating factor receptor subunits in murine hematopoietic
            cells stimulated with hematopoietic growth factors
  JOURNAL   Blood 80 (5), 1183-1189 (1992)
   PUBMED   1387562
REFERENCE   7  (bases 1 to 4776)
  AUTHORS   Gorman,D.M., Itoh,N., Jenkins,N.A., Gilbert,D.J., Copeland,N.G. and
            Miyajima,A.
  TITLE     Chromosomal localization and organization of the murine genes
            encoding the beta subunits (AIC2A and AIC2B) of the interleukin 3,
            granulocyte/macrophage colony-stimulating factor, and interleukin 5
            receptors
  JOURNAL   J Biol Chem 267 (22), 15842-15848 (1992)
   PUBMED   1386365
REFERENCE   8  (bases 1 to 4776)
  AUTHORS   Park,L.S., Martin,U., Sorensen,R., Luhr,S., Morrissey,P.J.,
            Cosman,D. and Larsen,A.
  TITLE     Cloning of the low-affinity murine granulocyte-macrophage
            colony-stimulating factor receptor and reconstitution of a
            high-affinity receptor complex
  JOURNAL   Proc Natl Acad Sci U S A 89 (10), 4295-4299 (1992)
   PUBMED   1533931
REFERENCE   9  (bases 1 to 4776)
  AUTHORS   Hara,T. and Miyajima,A.
  TITLE     Two distinct functional high affinity receptors for mouse
            interleukin-3 (IL-3)
  JOURNAL   EMBO J 11 (5), 1875-1884 (1992)
   PUBMED   1582416
REFERENCE   10 (bases 1 to 4776)
  AUTHORS   Fung,M.C., Mak,N.K., Leung,K.N. and Hapel,A.J.
  TITLE     Distinguishing between mouse IL-3 and IL-3 receptor-like
            (IL-5/GM-CSF receptor converter) mRNAs using the polymerase chain
            reaction method
  JOURNAL   J Immunol Methods 149 (1), 97-103 (1992)
   PUBMED   1583316
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL583893.17, AK152608.1 and AI467222.1.
            
            On Jan 19, 2008 this sequence version replaced NM_007780.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154286.1, AK155109.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-61                AL583893.17        97117-97177
            62-3394             AK152608.1         2-3334
            3395-4365           AL583893.17        120758-121728
            4366-4776           AI467222.1         1-411               c
FEATURES             Location/Qualifiers
     source          1..4776
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 37.36 cM"
     gene            1..4776
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /note="colony stimulating factor 2 receptor, beta,
                     low-affinity (granulocyte-macrophage)"
                     /db_xref="GeneID:12983"
                     /db_xref="MGI:MGI:1339759"
     exon            1..109
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            110..346
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..2949
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /note="GM-CSF/IL-3/IL-5 receptor common beta-chain; CD131
                     antigen; cytokine receptor common subunit beta;
                     GM-CSF/IL-3/IL-5 receptor common beta subunit; colony
                     stimulating factor 2 receptor, beta 1, low-affinity
                     (granulocyte-macrophage); beta c; common beta chain"
                     /codon_start=1
                     /product="cytokine receptor common subunit beta precursor"
                     /protein_id="NP_031806.3"
                     /db_xref="CCDS:CCDS27612.1"
                     /db_xref="GeneID:12983"
                     /db_xref="MGI:MGI:1339759"
                     /translation="MDQQMALTWGLCYMALVALCWGHGVTEAEETVPLKTLQCYNDYT
                     NHIICSWADTEDAQGLINMTLYHQLEKKQPVSCELSEELMWSECPSSHRCVPRRCVIP
                     YTRFSITNEDYYSFRPDSDLGIQLMVPLAQNVQPPLPKNVSISSSEDRFLLEWSVSLG
                     DAQVSWLSSKDIEFEVAYKRLQDSWEDAYSLHTSKFQVNFEPKLFLPNSIYAARVRTR
                     LSPGSSLSGRPSRWSPEVHWDSQPGDKAQPQNLQCFFDGIQSLHCSWEVWTQTTGSVS
                     FGLFYRPSPVAPEEKCSPVVKEPPGASVYTRYHCSLPVPEPSAHSQYTVSVKHLEQGK
                     FIMSYNHIQMEPPTLNLTKNRDSYSLHWETQKMAYSFIEHTFQVQYKKKSDSWEDSKT
                     ENLDRAHSMDLSQLEPDTSYCARVRVKPISNYDGIWSKWSEEYTWKTDWVMPTLWIVL
                     ILVFLILTLLLILRFGCVSVYRTYRKWKEKIPNPSKSLLFQDGGKGLWPPGSMAAFAT
                     KNPALQGPQSRLLAEQQGESYAHLEDNNVSPLTIEDPNIIRVPPSGPDTTPAASSEST
                     EQLPNVQVEGPTPNRPRKQLPSFDFNGPYLGPPQSHSLPDLPDQLGSPQVGGSLKPAL
                     PGSLEYMCLPPGGQAQLVPLSQVMGQGQAMDVQCGSSLETSGSPSVEPKENPPVELSM
                     EEQEARDNPVTLPISSGGPEGSMMASDYVTPGDPVLTLPTGPLSTSLGPSLGLPSAQS
                     PSLCLKLPRVPSGSPALGPPGFEDYVELPPSVSQAAKSPPGHPAPPVASSPTVIPGEP
                     REEVGPASPHPEGLLVLQQVGDYCFLPGLGPGSLSPHSKPPSPSLCSETEDLVQDLSV
                     KKFPYQPMPQAPAIQFFKSLKHQDYLSLPPWDNSQSGKVC"
     exon            347..470
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            471..658
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            659..816
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            817..985
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1121
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1282
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1422
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            1423..1582
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            1583..1673
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1731
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            1732..1835
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     exon            1836..4765
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4725..4730
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /note="hexamer: AATAAA"
     regulatory      4744..4749
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /note="hexamer: AATAAA"
     polyA_site      4758
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
     polyA_site      4765
                     /gene="Csf2rb"
                     /gene_synonym="AIC2B; Bc; CDw131; Csf2rb1; Csfgmrb; Il3r;
                     Il3rb; Il3rb1; Il5rb"
                     /note="major polyA site"
ORIGIN      
        1 aatctgctct ctgtttcctc cagatggggc acagataaat aggaagagcc tgcaactcac
       61 tggcacttgg aggctcccga aggaggctgc ctgtcgccca agcacagagc cacaaaggat
      121 gcagtctagg agggaagaat cacaagccct gtaagatgag tggagccaaa cccccagcca
      181 agcaccaata cagaaccccg ggacaatgag gacacccccc tgcccatagc ttccagtgca
      241 gccaccaaaa gtgccaaaat ggaccagcaa atggcactca catgggggct gtgctacatg
      301 gcactggtgg ctctctgttg gggacacggg gtgacagagg cagaagaaac ggtccctctg
      361 aagactctgc agtgctacaa tgactacacc aaccacatca tctgcagctg ggcggacaca
      421 gaggatgccc aggggctaat caacatgacc ctctatcacc agctagagaa aaaacagcca
      481 gtgtcctgtg agctcagtga ggaactcatg tggtcagagt gcccgtcatc ccaccgctgt
      541 gtgcccagaa gatgtgtcat cccctataca cgattttcca tcacaaacga agactactac
      601 tccttccggc cagatagtga tctgggcatc cagctcatgg tgccacttgc ccagaatgtg
      661 cagccaccac ttcccaagaa cgtcagcatc agctcctctg aggatcgttt cctgctggag
      721 tggagtgtgt cccttgggga tgcccaggtc tcctggcttt catcaaagga catagagttt
      781 gaggtggctt ataagcggct tcaggactcc tgggaggatg cctacagtct ccacactagc
      841 aaatttcagg tgaatttcga gccaaagcta ttcctaccca acagcatcta tgctgcccgt
      901 gtgcgcactc ggctgtcccc gggttcaagc ttgtctggga gacccagcag atggagccca
      961 gaggttcact gggactccca gccaggggac aaggcccagc cacagaacct tcaatgcttc
     1021 tttgatggga tccagtccct ccactgctcc tgggaggtgt ggacccagac gactggctct
     1081 gtttcctttg ggctcttcta tcgccccagc cctgtagctc cggaggagaa atgctctccg
     1141 gtggtgaagg agccgccggg ggccagtgtc tacacccgct accattgcag tctacctgtg
     1201 cctgagccca gtgcacacag ccagtacaca gtctctgtta agcacctgga acaagggaag
     1261 ttcatcatga gctataacca catccagatg gagcctccaa ccctcaacct gaccaagaac
     1321 agagacagct acagcctgca ttgggaaact cagaagatgg cttactcatt cattgagcac
     1381 acattccagg tccagtacaa gaagaaatcg gacagctggg aggacagcaa gacagagaac
     1441 ctagatcgag cccatagcat ggacctctcc cagctggagc cagacacctc atactgcgcc
     1501 agggtgaggg tcaagcccat ctctaactac gatgggatct ggagcaagtg gagcgaagag
     1561 tacacttgga agactgactg ggtgatgccc acgctgtgga tagtcctcat cctggtcttt
     1621 ctcatcctca ccttgctcct gatccttcgc tttggctgtg tctctgtata caggacgtac
     1681 aggaagtgga aggaaaagat ccccaacccc agcaagagcc tcctgttcca ggatggaggt
     1741 aaaggtctct ggcctcctgg cagcatggca gccttcgcca ctaagaaccc cgctctccag
     1801 gggccacaga gcaggcttct tgctgagcaa cagggggagt catatgcaca tttggaagac
     1861 aacaacgtgt cacctctcac tatagaggac cctaatataa ttcgagttcc accatccggg
     1921 cctgatacaa ccccagctgc ctcatccgaa tccacagagc aacttcccaa tgttcaagta
     1981 gagggaccaa ctcctaacag acctaggaag caattaccca gctttgactt caatgggccc
     2041 tacctggggc ctccccaatc ccactctctg cctgatctcc cagaccagct gggttccccc
     2101 caggtgggtg ggagcctgaa gccagcactg ccaggctcct tggagtacat gtgtctgccc
     2161 cctggaggtc aagcgcaact ggttccattg tcccaggtga tggggcaggg ccaggctatg
     2221 gatgtgcagt gtgggtccag cctggagacc tcagggagcc cttctgtgga gccaaaggag
     2281 aaccctccag ttgagctgag catggaggaa caggaggcac gggacaaccc agtgactctg
     2341 cccataagct ctgggggccc tgagggcagt atgatggcct ctgattatgt cactcctgga
     2401 gatccggtgc tcactctgcc cacagggccc ctgtctacct ctctgggccc ctctctaggg
     2461 ttgccctcag cccaaagccc cagtctctgt cttaagctgc ccagggtccc ctctggaagc
     2521 ccagctctag ggccaccagg gtttgaggac tatgtggagc tgcctccaag tgtgagccag
     2581 gctgccaagt cccctccagg ccatcctgct cctcctgtgg caagcagccc cacagtgatc
     2641 ccaggagagc ccagggagga agtgggccca gcatccccac atcccgaagg cctccttgtt
     2701 cttcagcagg ttggggacta ctgcttcctc cctggcctgg gacctggctc cctctcacca
     2761 cacagtaagc caccctctcc aagtctgtgt tctgagactg aggacctagt ccaggacttg
     2821 tctgtcaaaa agtttcccta tcagcccatg ccccaggcgc cagccattca gtttttcaag
     2881 tccctaaagc atcaggacta cctgtccctg cccccttggg acaatagcca gtctgggaag
     2941 gtgtgctgag tctgtctcct cccaatctca ccagcagcct ggcaccgcag cctgtggtcc
     3001 tcagcctgag catcaccaca gaagcctctc tgagttcaca ctcctccttg ctcccagccc
     3061 tgacatggca ataccccacc tgtgcttttc tcttccccct ctgtccctct tcccctccct
     3121 ccatgcaccc ccatctctct ctctgcagtt ttctgccttc tatgggaact tccttcctat
     3181 tcctctgacc tgttggagtg gggatgaggc ctgtgagggt atgggctgtt tagggtttac
     3241 aaacctgtga ggccggacgg tggtggcgca ttcccttaat cccagcactc tggaggcaga
     3301 ggcaggcaga tttctgagtt tgagtccagc ctggtctaca aagtgagttc caggacagcc
     3361 aggactatac agagaacccc tgtctcgaga aaccaaaaag aaaaaaaaaa aagaactgct
     3421 gaggtcggct tgtccaccac aggcattggt aatacagcac atttctggct ctgtgtgaaa
     3481 ggtgggagtc tcaggtgagc cccttgggag gtcagactgt acaattgggc aggctcttgt
     3541 cgctacaaga atagacatgg tcctctatgg ttgtctgaaa ctcctgggga gacctgggga
     3601 accttgtaga gggtacttgg taccctcctt atatacagaa atcactgatg tgcacaaagc
     3661 tggacacagc tatggccagg ctggagggat gagaagcaat gggaaggctg tgtgtctaga
     3721 actcatggtc tcaactgcag acaagcttag ttgtggatcc tggacagcac acccagatac
     3781 taagtctaga cagctgagct gttcgttagt tctccctcca gagcaaagcc tggatacctg
     3841 tgctcccacc ggcctcagat gagggtctgc tgtgagactg tggcccttgg ccatcaccac
     3901 cctcttgaca atccatgcac aatgccatta cctcattctg ttctcactgg agttgtttgt
     3961 tcatggtcac gtttgcacat ggcctttgtg tgtgtctcga gcattggctt tttgggtggt
     4021 agcgaggaag tagacttgga agttgagctc atgaacagtt ttgtgcttca gactgtcttt
     4081 tttggatgag actgaatagc tcttcccaca tggcctcttg tgggccacac gtgtctcccc
     4141 tgagtgtcct aattttgtgc aggaggcaca ccagctctgt cagccattgc gtgtctgcat
     4201 tgctatgaga tgggttgccg agccacacct gtctttgggt ccctgtttgc aggggtcttt
     4261 gctgtaagtg cacacgtgcc tttgtttatg ttctttctgg ttccttctgt gtctaaagcc
     4321 ttgagtgaga gacttggagt tttctagaac acatgatctc tctacagagt tcagtcttga
     4381 tgtgttctat ggacctggag tcaatggaca ttgtatcatt tcttcaccta tttgtgctct
     4441 gtcaggcact ccatgatcca ccaagtcatg aactggatct ggtctgtcct atcccctggc
     4501 ctcactcaca tgatggcaga catagaatgt ggcagatcaa atgtcccttg gtctctgttc
     4561 attgcagcaa agaaaaccac taacatcttg agtgtgttgc agtggcaatg ttcaacatca
     4621 gcctgtcaat actttccaaa gtgaccactc tagagaaaca aacaggagtg gcctccatgt
     4681 taagatgtga atgccaaagt gccttgcata agaggaaata ttgtaataaa catgtttaca
     4741 tacaataaaa cagcaaaaca aggcaaaaaa aaaaaa
//
