LOCUS       NM_133679               1809 bp    mRNA    linear   ROD 16-JUN-2024
DEFINITION  Mus musculus crystallin zeta like 1 (Cryzl1), transcript variant 1,
            mRNA.
ACCESSION   NM_133679
VERSION     NM_133679.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1809)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1809)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   3  (bases 1 to 1809)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   4  (bases 1 to 1809)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   5  (bases 1 to 1809)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY717916.1, AK145827.1 and BU757748.1.
            
            On Feb 16, 2011 this sequence version replaced NM_133679.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK008846.1, SRR1660817.283167.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-178               BY717916.1         2-179
            179-1654            AK145827.1         3-1478
            1655-1809           BU757748.1         1-155               c
FEATURES             Location/Qualifiers
     source          1..1809
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 53.26 cM"
     gene            1..1809
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /note="crystallin zeta like 1"
                     /db_xref="GeneID:66609"
                     /db_xref="MGI:MGI:1913859"
     exon            1..245
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            246..317
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             252..1298
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     quinone oxidoreductase-like protein 1; zeta-crystallin
                     homolog; quinone oxidoreductase homolog 1; crystallin,
                     zeta (quinone reductase)-like 1; ferry endosomal RAB5
                     effector complex subunit 4"
                     /codon_start=1
                     /product="quinone oxidoreductase-like protein 1 isoform 1"
                     /protein_id="NP_598440.1"
                     /db_xref="CCDS:CCDS37401.1"
                     /db_xref="GeneID:66609"
                     /db_xref="MGI:MGI:1913859"
                     /translation="MKGLYFQQSSTNEEVTFVFQEKENVPVTEDNFVRVQVKACALSH
                     INTKLLAEMKMEKDFFPVGREVSGIVLEVGRKVTFFQPDDEVVGILPLDSEDPGLCEV
                     IRVHEHYLVHKPEKVSWTEAAGVIRDGVRACTALYYLSQLSPGKSVLIMDGASAFGTI
                     AIQLAHHRGAKVISTAHSLEDKQHLERLRPSIARVIDVSNGKVHVAESCLEETGGLGV
                     DIVIDAGVRLYSKDDEPAVKLHLPHKHDIITLLGVGGHWVTTEENLQLDPPDSHCLFL
                     KGATVAFLNDEVWNLSNAQQGKYLCILKDVMEKLSAGVFRPLLDEPIPLYEAKVSMEV
                     VQKNQERKKQVVQF"
     exon            318..395
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            396..468
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            469..513
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            514..582
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            583..716
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            717..828
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            829..927
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1046
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1152
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1198
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1792
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1384..1389
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /note="hexamer: GATAAA"
     polyA_site      1409
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /note="major polyA site"
     regulatory      1625..1630
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /note="hexamer: AATACA"
     polyA_site      1657
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
                     /note="major polyA site"
     polyA_site      1792
                     /gene="Cryzl1"
                     /gene_synonym="2210407J23Rik; 2410006O11Rik; QOH-1"
ORIGIN      
        1 tttattggtg gtccctgggg cggcgactcg tctctctacg ggaagcagca tgctgggaga
       61 tgtagttccg ggttcagttg ccatggcgtt cgtcacagcc tcccccagat cggtcatcct
      121 gcggtagtga cgggcagtct gaccaatggc agtactgttt ggacccaaga aggcgggctc
      181 tctgcagaag gactgggaag gtggcggcgg cgaaggcgct ggcggttgag gttgctccga
      241 gccaggtaac tatgaaaggc ttgtattttc aacagagttc tacaaatgaa gaagtaacat
      301 ttgtatttca agaaaaggaa aatgtccctg tcacagagga taactttgtg agagttcaag
      361 ttaaagcttg tgccctgagc cacataaaca caaagcttct agcagaaatg aagatggaaa
      421 aggatttctt ccctgttgga agagaagttt ctggaattgt attagaggtt ggcaggaagg
      481 taacgttctt tcagccagac gacgaagtgg tcggaattct gcctttggat tccgaagacc
      541 ccgggctctg tgaggttatt cgagtacatg agcattacct ggttcataag ccagaaaagg
      601 tgtcatggac ggaagctgct ggcgtcatcc gggacggagt ccgagcctgc acagctctgt
      661 attatctttc tcaactctct cctggaaagt ctgtgctgat catggacggg gcaagtgcat
      721 ttggcacaat agccattcag ttagcccacc acagaggagc caaggttatc tcaacagcac
      781 acagcctgga ggacaagcaa catcttgaaa ggcttaggcc ttctatagcc cgtgtgattg
      841 atgtgtctaa tgggaaagtc catgttgctg aaagctgttt ggaggaaaca ggtggcctgg
      901 gagtagatat tgtcatagat gcaggagtga gattatatag taaagatgat gaaccagctg
      961 taaagttaca tctgccacat aagcatgaca tcatcacact tcttggtgtc ggaggccatt
     1021 gggtaacaac agaagaaaac cttcagttgg atcctccaga tagccactgc cttttcctca
     1081 agggagcaac ggtggctttc cttaatgatg aagtttggaa tttgtcaaat gcacaacagg
     1141 gaaaatatct ttgtatctta aaagatgtga tggagaagtt atcagctggt gttttcaggc
     1201 ctctgctcga tgagcccatc ccactgtatg aggcaaaggt ttccatggaa gttgttcaga
     1261 aaaatcaaga aagaaaaaag caagtcgttc aattttaatt ctcttccctg atctcagtcg
     1321 gatgcaccca caccagtggg ggaagccagt tttctttgga aattgttgag aaaaaccaag
     1381 gacgataaag caagatttta tatttttaag cctgttttcc tgccacagta agatgtttgg
     1441 ttatttgaca tatttgaaaa atacttccaa aattaatgtg caaacaatcc agataatttt
     1501 tttaccatct gaaggggaca ttccaaaagc ttcttttagt tattgtatct gtacactttg
     1561 cctctgctat aaaattcttt ccattaagaa aactgctttc agcaaaagct acactattct
     1621 agcaaataca tctgtcacat gcttttgcta taccaaacgt catttgattt tgttatcaac
     1681 ttcattctca acaccttcct taacaaaccg ttgatgccat tattttagca tttgtacttt
     1741 ccgacttcaa agtatctaat ccactggcat ttaaaatgtt tttaaatatt caaaaaaaaa
     1801 aaaaaaaaa
//
