LOCUS       NM_007776                630 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus crystallin, gamma D (Crygd), mRNA.
ACCESSION   NM_007776
VERSION     NM_007776.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Schmid,P.W.N., Lim,N.C.H., Peters,C., Back,K.C., Bourgeois,B.,
            Pirolt,F., Richter,B., Peschek,J., Puk,O., Amarie,O.V., Dalke,C.,
            Haslbeck,M., Weinkauf,S., Madl,T., Graw,J. and Buchner,J.
  TITLE     Imbalances in the eye lens proteome are linked to cataract
            formation
  JOURNAL   Nat Struct Mol Biol 28 (2), 143-151 (2021)
   PUBMED   33432246
REFERENCE   2  (bases 1 to 630)
  AUTHORS   Vetrivel,S., Tiso,N., Kugler,A., Irmler,M., Horsch,M., Beckers,J.,
            Hladik,D., Giesert,F., Gailus-Durner,V., Fuchs,H., Sabrautzki,S.,
            Hrabe de Angelis,M. and Graw,J.
  TITLE     Mutation in the mouse histone gene Hist2h3c1 leads to degeneration
            of the lens vesicle and severe microphthalmia
  JOURNAL   Exp Eye Res 188, 107632 (2019)
   PUBMED   30991053
REFERENCE   3  (bases 1 to 630)
  AUTHORS   Aoki,H., Ogino,H., Tomita,H., Hara,A. and Kunisada,T.
  TITLE     Disruption of Rest Leads to the Early Onset of Cataracts with the
            Aberrant Terminal Differentiation of Lens Fiber Cells
  JOURNAL   PLoS One 11 (9), e0163042 (2016)
   PUBMED   27631609
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 630)
  AUTHORS   Zhang,R., Huang,H., Cao,P., Wang,Z., Chen,Y. and Pan,Y.
  TITLE     Sma- and Mad-related protein 7 (Smad7) is required for embryonic
            eye development in the mouse
  JOURNAL   J Biol Chem 288 (15), 10275-10285 (2013)
   PUBMED   23426374
REFERENCE   5  (bases 1 to 630)
  AUTHORS   Xie,Q. and Cvekl,A.
  TITLE     The orchestration of mammalian tissue morphogenesis through a
            series of coherent feed-forward loops
  JOURNAL   J Biol Chem 286 (50), 43259-43271 (2011)
   PUBMED   21998302
REFERENCE   6  (bases 1 to 630)
  AUTHORS   Serikawa,T., Kuramoto,T., Hilbert,P., Mori,M., Yamada,J.,
            Dubay,C.J., Lindpainter,K., Ganten,D., Guenet,J.L., Lathrop,G.M. et
            al.
  TITLE     Rat gene mapping using PCR-analyzed microsatellites
  JOURNAL   Genetics 131 (3), 701-721 (1992)
   PUBMED   1628813
REFERENCE   7  (bases 1 to 630)
  AUTHORS   Goring,D.R., Breitman,M.L. and Tsui,L.C.
  TITLE     Temporal regulation of six crystallin transcripts during mouse lens
            development
  JOURNAL   Exp Eye Res 54 (5), 785-795 (1992)
   PUBMED   1623964
REFERENCE   8  (bases 1 to 630)
  AUTHORS   Levan,G., Szpirer,J., Szpirer,C., Klinga,K., Hanson,C. and
            Islam,M.Q.
  TITLE     The gene map of the Norway rat (Rattus norvegicus) and comparative
            mapping with mouse and man
  JOURNAL   Genomics 10 (3), 699-718 (1991)
   PUBMED   1889815
REFERENCE   9  (bases 1 to 630)
  AUTHORS   Masaki,S. and Watanabe,T.
  TITLE     Linkage analysis of the mutation locus in the eye lens obsolescence
            (Elo) mouse
  JOURNAL   Genomics 5 (2), 259-263 (1989)
   PUBMED   2571575
REFERENCE   10 (bases 1 to 630)
  AUTHORS   Adkison,L.R., Skow,L.C., Thomas,T.L., Petrash,M. and Womack,J.E.
  TITLE     Somatic cell mapping and restriction fragment analysis of bovine
            genes for fibronectin and gamma crystallin
  JOURNAL   Cytogenet Cell Genet 47 (3), 155-159 (1988)
   PUBMED   2897897
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158958.4.
            
            On Oct 31, 2022 this sequence version replaced NM_007776.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF739639.1, CF739413.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                AC158958.4         195167-195212       c
            47-289              AC158958.4         194832-195074       c
            290-630             AC158958.4         193615-193955       c
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 32.8 cM"
     gene            1..630
                     /gene="Crygd"
                     /gene_synonym="Aey4; Cryg-1; DGcry-1; Lop12"
                     /note="crystallin, gamma D"
                     /db_xref="GeneID:12967"
                     /db_xref="MGI:MGI:88524"
     exon            1..46
                     /gene="Crygd"
                     /gene_synonym="Aey4; Cryg-1; DGcry-1; Lop12"
                     /inference="alignment:Splign:2.1.0"
     exon            47..289
                     /gene="Crygd"
                     /gene_synonym="Aey4; Cryg-1; DGcry-1; Lop12"
                     /inference="alignment:Splign:2.1.0"
     exon            290..630
                     /gene="Crygd"
                     /gene_synonym="Aey4; Cryg-1; DGcry-1; Lop12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      602..607
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Crygd"
                     /gene_synonym="Aey4; Cryg-1; DGcry-1; Lop12"
                     /note="hexamer: AATAAA"
     polyA_site      630
                     /gene="Crygd"
                     /gene_synonym="Aey4; Cryg-1; DGcry-1; Lop12"
                     /note="major polyA site"
ORIGIN      
        1 caacagcacc atcccatccg acctgccaac accagccatg gggaagatca ccttctatga
       61 ggaccgcggc ttccagggcc gccactatga gtgcagcacc gaccactcca acctgcagcc
      121 ctacttcagc cgctgcaact ctgtgcgcgt ggacagtggc tgctggatgc tctatgagca
      181 gcccaacttc acgggctgcc agtacttcct gcgtcgcggg gactaccctg actaccagca
      241 gtggatgggt ttcagtgact ctgtccgctc ctgccgcctc atcccccacg ccggctctca
      301 caggatcaga ctgtacgaga gggaagagta cagaggccag atgatagagt tcacggagga
      361 ctgcccctct ctccaggacc gattccactt caatgagatc tactccctca atgtgctaga
      421 gggctgctgg gtcctctacg acatgaccaa ctaccgggga aggcagtact tgctcagacc
      481 cggggagtac aggcgctacc acgactgggg cgccatgaat gccagggtgg gctctctgag
      541 gagagtcatg gatttctact gaattggttt ttttactcta ccctttctcc atttggacgc
      601 taataaaata ttttctgtgt gttcctggca
//
