LOCUS       NM_001368306            7320 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus crystallin beta-gamma domain containing 1 (Crybg1),
            transcript variant 2, mRNA.
ACCESSION   NM_001368306 XM_006512499
VERSION     NM_001368306.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7320)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7320)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   3  (bases 1 to 7320)
  AUTHORS   Tamplin,O.J., Cox,B.J. and Rossant,J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
REFERENCE   4  (bases 1 to 7320)
  AUTHORS   Chalhoub,N., Benachenhou,N. and Vacher,J.
  TITLE     Physical and transcriptional map of the mouse Chromosome 10
            proximal region syntenic to human 6q16-q21
  JOURNAL   Mamm Genome 12 (12), 887-892 (2001)
   PUBMED   11707774
REFERENCE   5  (bases 1 to 7320)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   6  (bases 1 to 7320)
  AUTHORS   Teichmann,U., Ray,M.E., Ellison,J., Graham,C., Wistow,G.,
            Meltzer,P.S., Trent,J.M. and Pavan,W.J.
  TITLE     Cloning and tissue expression of the mouse ortholog of AIM1, a
            betagamma-crystallin superfamily member
  JOURNAL   Mamm Genome 9 (9), 715-720 (1998)
   PUBMED   9716656
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153534.2 and AC158637.3.
            
            On Feb 5, 2019 this sequence version replaced XM_006512499.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-184               AC153534.2         96779-96962         c
            185-1647            AC153534.2         78115-79577         c
            1648-3943           AC153534.2         71739-74034         c
            3944-3991           AC153534.2         67345-67392         c
            3992-4110           AC153534.2         67142-67260         c
            4111-4270           AC153534.2         63781-63940         c
            4271-4410           AC153534.2         60938-61077         c
            4411-4537           AC158637.3         220646-220772       c
            4538-4573           AC158637.3         217963-217998       c
            4574-4731           AC158637.3         216192-216349       c
            4732-4858           AC158637.3         215059-215185       c
            4859-5004           AC158637.3         214823-214968       c
            5005-5131           AC158637.3         208854-208980       c
            5132-5164           AC158637.3         208630-208662       c
            5165-5277           AC158637.3         207466-207578       c
            5278-5407           AC158637.3         205743-205872       c
            5408-5547           AC158637.3         202594-202733       c
            5548-5671           AC158637.3         199979-200102       c
            5672-5830           AC158637.3         199413-199571       c
            5831-5993           AC158637.3         197814-197976       c
            5994-7320           AC158637.3         191796-193122       c
FEATURES             Location/Qualifiers
     source          1..7320
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 23.14 cM"
     gene            1..7320
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /note="crystallin beta-gamma domain containing 1"
                     /db_xref="GeneID:11630"
                     /db_xref="MGI:MGI:109544"
     exon            1..184
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     CDS             182..6082
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     absent in melanoma 1"
                     /codon_start=1
                     /product="beta/gamma crystallin domain-containing protein
                     1 isoform 2"
                     /protein_id="NP_001355235.1"
                     /db_xref="GeneID:11630"
                     /db_xref="MGI:MGI:109544"
                     /translation="MSRAQPPEDTRRKPVLEKLGTLFTAGRRRNTRNGLESPTNSNSK
                     SASAKVPKTGSEKTKAQDNQLKATDAGEAGPRQEAEGQPVESCVQATPCDAEQSPCSS
                     INVGVVQQCHSNDSAQLEPLQAEGETFPDATTAAKELLHSSPGNRSRQESAETPARSP
                     GEEALPGAGLQPETARGVSGSPPEEHLVGGVGEAPDGAPGVGAEAGSLGAPGDAVPPG
                     EPPAQDAETSRTAGSVDRAHPTKVLTLDIYLSKTEVAQVDEPASIAPGTDDCEDSDDM
                     EKRSSGRRSGRRRKSQKSTDSPGADAVAPESAAKDEAVFDDEVAPDAAAENCLAERKV
                     KSVQAVPDGGAAPVACPEPKASSCPRGQPRGEPDRSKPLSPTKRKGRSRVPEAVPSSP
                     GSGSRAPAKESPPKRAPAAADSGEEAGRVVPRELTVKSSSLLPEIKPEHKRGPLPHHF
                     DSRGDGGRSRGTGASDADGLKPRNQFGVGRSTVTTKVTLPARPKHVELNLKTPKNPDS
                     LGNEHNSFSQPVHKGNTANKISLFENKRANSSPRHPDVRNTRNNPPSSKTFVGRAKLN
                     LAKKAKEMEQPEKKAVSTSHQNGLVVKEPSAEGKGTAVPVPREEIRPATRGGEGESTK
                     DQVLRPEPEQSDKLDVQTDTAYPSHPGPTALVPVKDSELSGEGQPEAADSKGPVLNNT
                     SDVAQDIAAICDAREAPPKPQDAFSDSQPASAAESARESSLPPSAPISVDAPQDGCVQ
                     VPICSVPCTALEVSENHNGCVSPVSPHTEKTPISKPGVGEASPPSTPEHSPETMGKDC
                     PSKVLVQVRSFVLPVENPQDVSSQVISESSEVREAQLPSCHSNEPEVVSVTTCVPQHE
                     DAPDTSPKDIHHREGHVAQSRPHITQSGPEKAPPIQSSSGMPQTAEFILTHSPSSRSH
                     AEGPQRPGQDATSPLTPTRLLNISAGSDNSVLDSSSDMEKFTEIIKKMDSAVCVPQKK
                     KKARVPNSPAPHFAMPPIHEDSLEKVFDPNVFTIGLGKKKESLAEVSPALHLLQNHDP
                     ISKLRAKRASTEQSIVFKSLHTNSNGKSEPQTTSEASDKENRDINSGGVKRSRLENST
                     LFSSMLSSLPQDKVFSPSVTSVNTMSTSFSTSQNSSVSQSSVVQPRKEGGLPCGSDKE
                     QPHLAPHNSLKVFNFNSSNTSRLGSSHMEKYPQKEGSKEDVNSQGNLQLPENNLSDLP
                     KLKNSDGVEGILKSNLPNVGSVDADFLGLFKASRYDPGHSFSGMSLSDSMTLRGSMHS
                     KLNPRPGKVVIFSEPDVSEECIEVFGDIQDCSSWRLSPVIVVKVVRGCWILYEKANFE
                     GHSLALEEGELELSSIWGTEEMLDEEAESDKPVVIGSIRHVVQDYRISQIDLFTEPEG
                     LGLLNSYFDDTEEMQGFPVMQKTCSIKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSF
                     WDTEEAYIGSMRPLKMGGRKVEFPTDPKVVIYEKPSFEGRCMELETEMSSFIMEGGET
                     EETTGNNNLPFTSVGSMKVLRGVWVAYEKCGFTGHQYLLEEGEYRDWNAWGGYNGELQ
                     SLRPILSDFSNAHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWV
                     AYENPDFTGEQYVLDKGFYTSFEDWGGKNCKISSVQPICLDSFTGPRRRNQIHLFSEP
                     QFQGQSQSFEETIDQIDDSFQTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPCLSAM
                     GCLPGATLKSLRFIDFEFSEPTIILFERENFKGKKIELNAETVNLRSLGFNTQIRSVR
                     VVGGIWVTYEYGNYRGRQFLLSPAEVPNWYEFSACRQIGSLRPFAQKRIYFRLRNKAT
                     GLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQEGCIKCRIAEDCCLTIVGSLVTSG
                     SKLGLALDQNVDSQFWCMKSDGRIYSKMKPNLVLDVKGGAQYDQNHIILNTVSTEKLT
                     QVWEAMVL"
     exon            185..1647
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..3943
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            3944..3991
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            3992..4110
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            4111..4270
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            4271..4410
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            4411..4537
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            4538..4573
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            4574..4731
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            4732..4858
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            4859..5004
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            5005..5131
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            5132..5164
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            5165..5277
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            5278..5407
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            5408..5547
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            5548..5671
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            5672..5830
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            5831..5993
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     exon            5994..7320
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7292..7297
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /note="hexamer: ATTAAA"
     polyA_site      7317
                     /gene="Crybg1"
                     /gene_synonym="Aim1"
                     /note="major polyA site"
ORIGIN      
        1 agtgtctccg tttcagctct ggctacagag actgagctgc gggagttgaa cagggcagac
       61 tggaacttgg acaggctggg ctgtggtgag aagcagggta gaggggatgc aggccgagct
      121 gcctgctgct gcctgcagtc ttttggtgta tccataggaa gtggagaaga ggcaagacag
      181 catgtccaga gcacaaccac cagaagacac cagaaggaag ccagtgttgg aaaaacttgg
      241 cactcttttt acggctggaa ggagaaggaa caccaggaac ggattagaga gtcccaccaa
      301 ctcaaatagc aaatcggcct ctgctaaagt cccaaaaaca gggagtgaga aaactaaggc
      361 tcaggacaac caactaaagg caaccgacgc tggcgaggcg ggccccaggc aggaggctga
      421 gggccagccc gttgagagct gtgttcaggc aaccccctgc gacgccgaac agtcaccttg
      481 ctccagcatc aatgtagggg ttgtgcagca gtgccacagc aatgattcag cccaattaga
      541 acctctacag gcagagggag agactttccc agatgccacc accgctgcca aagagctgct
      601 gcattcctca ccagggaatc gctccaggca ggagagcgca gagacgcccg cccgcagtcc
      661 gggggaggaa gcgttgcctg gcgctggcct ccaaccagag acagcgagag gtgtgtcggg
      721 gtcgccgcca gaggagcacc tcgtgggagg agtaggagag gcccccgacg gagcccccgg
      781 cgtgggtgcc gaagcgggct ctctgggggc cccgggggac gcggttcctc caggtgagcc
      841 tcccgcccag gacgcagaga ccagccgcac agccgggtcg gtcgaccgcg cgcatcccac
      901 caaagtgcta acgttggaca tctacttgag caaaactgag gtggctcagg tggacgagcc
      961 ggcctcgatt gctccgggga cagacgactg cgaggattcg gacgacatgg aaaagaggtc
     1021 aagcggccgc cggtctggtc ggcggaggaa gtcgcagaaa tccaccgact ccccgggtgc
     1081 ggatgcggtg gctcccgaga gtgcggccaa ggacgaggcg gtgttcgacg acgaggtggc
     1141 gccagacgct gcggctgaga actgcttggc ggaaaggaaa gtgaaatcgg tacaagcggt
     1201 tcccgacgga ggcgcagccc cggtcgcctg cccggagcca aaggccagct cctgccccag
     1261 agggcaaccc cgaggggaac cggaccgcag caagcccctg tcgcccacca agcggaaggg
     1321 tcgcagccgt gtccccgagg cggtgcccag ctcgcccggc agtggctcgc gcgctcccgc
     1381 caaggagtcc ccacccaaga gggcgcccgc tgcggcggac agcggcgagg aggcgggccg
     1441 cgtcgtcccg cgcgagctca ccgtcaaaag cagctcgttg ctgcccgaga tcaagccaga
     1501 gcacaagagg ggtcctctgc cccaccactt tgatagccgg ggcgacgggg gtcgcagcag
     1561 gggaacagga gcgtccgacg ccgacggcct gaagcccagg aaccagttcg gtgtgggcag
     1621 gtctactgtg accaccaaag tgaccctccc cgccagaccc aaacatgtgg aactaaatct
     1681 gaaaactccg aagaatcctg acagtttggg aaatgagcac aactcattta gccagccagt
     1741 tcataagggg aacacagcca acaaaatctc cttatttgaa aacaagcggg ctaacagtag
     1801 cccccgccac cccgacgtcc gtaacacaag gaacaatcct ccctctagta agacatttgt
     1861 tgggagggcg aagctgaact tagccaaaaa ggccaaagaa atggagcaac ccgaaaagaa
     1921 agctgtgtca accagccacc agaatggcct ggtggtcaaa gagccatctg cagaagggaa
     1981 aggcacagca gtccctgtcc ccagagaaga gattcgtcca gccaccagag gaggggaagg
     2041 agagtccacc aaggatcagg tcctccgccc tgagcctgag caaagtgata agctggatgt
     2101 acaaacagac actgcctatc cttcccaccc agggcccact gctctggttc ctgtgaagga
     2161 ctctgagctc tcaggagagg gccagccaga ggctgctgac agcaaaggcc ccgtccttaa
     2221 caacacaagt gatgttgcac aggacatcgc tgccatttgt gatgccagag aggctccccc
     2281 aaagccacag gatgcatttt ctgactcaca gccagcttca gcggctgagt cagctaggga
     2341 gtcatctctc ccgccttctg cacccatttc tgtggacgct ccccaagatg gctgtgttca
     2401 agttcccata tgcagtgttc cctgcactgc tctagaagtg tcagaaaacc acaatgggtg
     2461 tgtttcgcca gtctctcctc acactgagaa aactcccatc tccaaacctg gagtgggaga
     2521 agccagtccc ccttccactc cagagcacag cccagaaact atggggaaag actgtccctc
     2581 caaagtcctc gtccaggtcc ggtcctttgt gcttcccgtg gagaatcctc aggatgtgag
     2641 ctctcaggtc atctcagaga gctctgaagt tagagaggca cagctgccaa gctgtcacag
     2701 taatgagcct gaagtggtgt ctgtcaccac ttgtgttccg cagcacgagg atgcaccaga
     2761 cacatcaccc aaggacatcc atcacagaga aggacatgtg gcacagtctc gaccacacat
     2821 cacacagtca ggacctgaga aggctccgcc catccagagc agcagtggga tgccccagac
     2881 agcggagttc atcctcaccc actctcccag cagcagaagt catgcagaag gcccccaaag
     2941 gccaggtcaa gatgcgacca gcccacttac ccctaccagg cttttgaaca tttctgctgg
     3001 tagtgacaat agtgtcttgg attcttcttc tgatatggaa aaattcactg aaattattaa
     3061 aaagatggac agtgcagtat gtgtgcccca gaaaaagaag aaggcccggg tcccaaactc
     3121 tccagcccct cacttcgcta tgcctcccat tcacgaggac agtttggaaa aggtgtttga
     3181 tcccaacgtg ttcaccattg gtttagggaa gaagaaggaa agcctggcag aggtgtcacc
     3241 agctttgcac ttgttgcaga accacgaccc catatccaaa ctgagagcca agcgtgcatc
     3301 caccgagcag agcatcgtct tcaagtcctt gcacactaac agtaatggga agagcgagcc
     3361 acagaccact tcagaagcaa gtgacaagga gaacagggac atcaacagcg gcggcgttaa
     3421 gaggtcacgg ctagaaaaca gcacgctttt ctcaagcatg ctttcttctc tgccacaaga
     3481 caaagtcttt tctccctccg tgacgtcagt caacacaatg agcacatctt ttagcacttc
     3541 tcagaacagc tccgtatctc agtcatcagt ggtacagccc aggaaggagg gtggcctgcc
     3601 ctgtggctca gacaaagaac agccacacct tgcaccccac aactccttaa aggtcttcaa
     3661 tttcaattca tcaaatacat ctcgtctggg ttccagccac atggaaaagt acccacaaaa
     3721 agagggaagc aaggaagatg tgaattctca gggcaaccta caattgccag aaaacaacct
     3781 ttcagactta cccaaactga agaacagcga tggcgtggaa ggtattctga agtcaaacct
     3841 gccgaatgtt gggagcgtgg acgcggactt cctgggcctt ttcaaagcaa gccggtatga
     3901 cccaggccat tccttttctg gaatgtcctt atcagactct atgactctta gaggaagtat
     3961 gcacagcaaa ctcaaccccc ggcctggcaa ggtagtgata ttcagtgagc ccgacgtctc
     4021 tgaggagtgc attgaggtgt ttggggacat ccaggactgc agctcctggc gcctctctcc
     4081 agtgatagta gtgaaagttg tccgaggatg ttggattttg tatgagaaag ccaattttga
     4141 agggcattct cttgctttag aagaaggtga actggaactc tctagtatct ggggaacaga
     4201 ggaaatgttg gatgaagaag cagagtctga taaacctgta gtgattggtt ccatcagaca
     4261 cgtggttcag gattacagaa ttagtcagat cgacttgttt actgagcctg aagggttagg
     4321 actcctgaac tcgtactttg atgacactga ggaaatgcag ggcttccctg tgatgcagaa
     4381 gacgtgttcc atcaaagtgc actggggcac atggctgatc tatgaagagc ctggattcca
     4441 aggtgtcccc ttcattctgg agcccggaga ataccctgac ctatccttct gggataccga
     4501 ggaagcgtac atcggatcca tgcggcctct gaaaatgggt ggccgtaaag ttgaattccc
     4561 tacagatcca aaggtagtta tttatgaaaa gccttccttt gaaggaaggt gtatggagct
     4621 agaaacagaa atgagtagtt ttatcatgga aggaggtgag acagaagaaa caactggaaa
     4681 caacaacttg ccctttacat ccgtggggtc tatgaaagtc ctaagaggcg tctgggttgc
     4741 ttatgagaag tgtggcttca ctggccacca gtatttgctg gaggagggag aatacaggga
     4801 ctggaacgcc tggggaggct acaatggaga gctccagtct ctgcggccta tattaagtga
     4861 tttttcaaat gcgcacatga taatgtacag tgagaagaac tttggctcca aaggttccag
     4921 tattgatgtg ttgggaattg ttgccaattt gaaggagacc ggctacggag tgaagacaca
     4981 gtcaatcaat gtactgagtg gcgtgtgggt agcctatgaa aacccggact tcacggggga
     5041 gcagtatgtc ctggataaag gcttctacac cagttttgag gattggggag gcaaaaattg
     5101 taagatctct tccgtccaac ccatatgcct ggattctttc actggcccca ggagacgaaa
     5161 tcagattcac ttgttttcag aaccacagtt ccaaggtcaa agtcaaagtt ttgaagaaac
     5221 aatagatcag attgacgact cctttcagac caagtcttgc agagttttgg gaggcagctg
     5281 ggttgcttat gatggagaaa atttctctgg caatcagtat gtactggaag aaggccacta
     5341 tccttgtctc tcggcaatgg gatgcctgcc tggagcaacc ctgaagtctc ttcgctttat
     5401 agattttgaa ttttccgaac caacaattat tcttttcgaa agagaaaact tcaaaggaaa
     5461 aaagatagaa ctgaacgcag aaacagtcaa tctccgatcc ttggggttca acactcagat
     5521 ccgctctgtg cgggtcgttg gtggcatatg ggttacctat gaatatggca attacagagg
     5581 ccggcagttc ctgctgtctc ctgcagaagt accaaactgg tatgagttca gtgcctgtcg
     5641 ccaaataggc tccctccggc cctttgctca gaaacgaatt tacttcagac ttcgaaacaa
     5701 agcaacagga ctatttatgt caaccaacgg gaacttggaa gacctgaagc ttctccgagt
     5761 ccaggtcatg gaagatgttg gtgctgatga tcagatctgg atctatcaag aagggtgcat
     5821 caaatgcagg atagcagaag actgctgcct gacgatcgtg ggcagcctcg tcacgtctgg
     5881 ctccaaacta ggactggccc tcgatcaaaa tgtcgacagt cagttctggt gcatgaagtc
     5941 cgacggcagg atctacagca agatgaaacc aaatttagtg ttggatgtga aagggggtgc
     6001 gcagtatgat caaaatcaca tcatcctcaa cacagtgagc acagagaagt taacacaagt
     6061 gtgggaagcc atggtcctgt gaacctgaac caagactgca ggaggagtat ttccagggga
     6121 ttttctggcc accttattga agaaaactaa aaattacaga gctgctggag gagccaagtg
     6181 gaaagtttcc gaaagccacg gcagacagaa tcatctcaaa aacatttgag tttgaagcca
     6241 atagtttgtt gttcttgttt tttgccttgt attttctcag ttccttcaac aggctgccct
     6301 ggtagcagct ttagggtata agatgtttta aagatcaaga caagaccaca tcacaatttt
     6361 tttccaggaa taggagggga caagacgtct gaatgtggac atacagattc ccttagagag
     6421 aaggataaaa gcccaagttg gttgttagaa gactttagca ttggagaacg tggtgccaga
     6481 cttctgatcc atggccttaa cacttccggg gaccatttat gctggatggc agagtggcaa
     6541 agtcctatat acttattcca aggagtttaa taagtataaa ccactatttt cagttactat
     6601 tcaaatgaat aaattttcaa aatttcatgt tgatatctgc tcatgaacag aacttgggtt
     6661 actttaattc acctacggac tgccctcaag tgtctacaga tacttcaatg ccttccttac
     6721 agctgctatt gggacagtat tatggcctaa tttattaacc cttactttac tatccacacc
     6781 taatgctgaa gccatactct atacttttag ctaaacaaag acctttcagc ctggtttctc
     6841 tagggccacc cgcaggatga ctgcttcata tccgaggaca ccaggacctc ccttgttgca
     6901 gagtgaggga gatgccaagg gttgtgcagt gttggtgcag aggggcccag acctcagtgg
     6961 gcagttcagg agcaactgtg tgatgcactg gccagacagc actgtccttt tacgacaaac
     7021 tgccagacat ccctggaaca tggcttcctc atcacagtac tggtgcccct gtcagaggct
     7081 gaacaaaccc catttctgct tcatctgttc aagcctgctt cctctctgga gccaaggata
     7141 ggcaagagat cgtcggaata gtctgtctgc agcacccagc ctgtctgtct tgttcttctg
     7201 tgtacatctc taactgtagt ccttttgtgt atgtcgctag agcacagtgg ggtaagatat
     7261 cctataaacg cctgttgagt ttgtctcttg aattaaactt attcctggtt aactacatga
//
