LOCUS       NM_001081200            1973 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus cornulin (Crnn), mRNA.
ACCESSION   NM_001081200 XM_355410
VERSION     NM_001081200.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1973)
  AUTHORS   Bebee TW, Park JW, Sheridan KI, Warzecha CC, Cieply BW, Rohacek AM,
            Xing Y and Carstens RP.
  TITLE     The splicing regulators Esrp1 and Esrp2 direct an epithelial
            splicing program essential for mammalian development
  JOURNAL   Elife 4, e08954 (2015)
   PUBMED   26371508
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1973)
  AUTHORS   Mlitz V, Strasser B, Jaeger K, Hermann M, Ghannadan M, Buchberger
            M, Alibardi L, Tschachler E and Eckhart L.
  TITLE     Trichohyalin-like proteins have evolutionarily conserved roles in
            the morphogenesis of skin appendages
  JOURNAL   J Invest Dermatol 134 (11), 2685-2692 (2014)
   PUBMED   24780931
REFERENCE   3  (bases 1 to 1973)
  AUTHORS   Contzler R, Favre B, Huber M and Hohl D.
  TITLE     Cornulin, a new member of the 'fused gene' family, is expressed
            during epidermal differentiation
  JOURNAL   J Invest Dermatol 124 (5), 990-997 (2005)
   PUBMED   15854041
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC135289.3.
            
            On Jun 20, 2019 this sequence version replaced NM_001081200.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BB618328.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN00849389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AC135289.3         25889-25938         c
            51-201              AC135289.3         23778-23928         c
            202-1973            AC135289.3         20909-22680         c
FEATURES             Location/Qualifiers
     source          1..1973
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.14 cM"
     gene            1..1973
                     /gene="Crnn"
                     /gene_synonym="Gm1015"
                     /note="cornulin"
                     /db_xref="GeneID:381457"
                     /db_xref="MGI:MGI:2685861"
     exon            1..50
                     /gene="Crnn"
                     /gene_synonym="Gm1015"
                     /inference="alignment:Splign:2.1.0"
     exon            51..201
                     /gene="Crnn"
                     /gene_synonym="Gm1015"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..1626
                     /gene="Crnn"
                     /gene_synonym="Gm1015"
                     /codon_start=1
                     /product="cornulin"
                     /protein_id="NP_001074669.1"
                     /db_xref="CCDS:CCDS38524.1"
                     /db_xref="GeneID:381457"
                     /db_xref="MGI:MGI:2685861"
                     /translation="MPQLLQNIHGIIEAFGCYARSEGGCKVLTRQELKRLLEHEFADV
                     IVKPHDPATVDEVLRLLDEDNTGTVEFKEFLVLVFKVARACFKTLNESPKGACISDKS
                     EGCYSGSSKELEQRQRGGAEVAKDGAAQHCEDSSCGQRDQASRGQDRVGTHTQNQDSY
                     PTQVSSHDRQTESQTQEMISQQTQVTGQVEQTPRTEDKSWTRQKRSERQPQSSQQTDE
                     ITTGSTAQTQAGNFYTQGSTCDYNRGTNSHHQDRSHADRASTQHYQTQAGSHTQIHTQ
                     MVEQAWGQQTGSDSIQTQGSIYDQSTETVIHGQDRNQASQSVKEHHQAQGESYIQTHT
                     QTMEQGRSQQAENSSTQTHGSMYGQNRETEIHGLESSQAEQVGTRHYQTQAGSYTQTL
                     EHDGSQSAHKFVAQEKERTQTKPCMGQSWTPVSNYETEESVIGGQVQTETDTIIENHP
                     SPTARQVERVPTVVREEWVNDHTREIVIRSQDPGSLHSGTPSAQGQDIPQMEKKGITA
                     KGLYTYLKTEQP"
     exon            202..1973
                     /gene="Crnn"
                     /gene_synonym="Gm1015"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actctacaca ctgcttaaca gaaacttgtc ccatcctgcc tgagcattag catagcttca
       61 aagatgcctc agttgctgca aaacatccac gggatcatcg aagccttcgg gtgctatgcc
      121 aggtcagagg gtggctgcaa agtactcacg aggcaggagt tgaagaggct cctggaacat
      181 gagtttgctg acgtcatagt gaagccccat gatcctgcaa ctgtggatga agtcctgcgc
      241 ctgttggatg aagataacac agggactgta gagttcaagg aattcctagt cttggtgttt
      301 aaagttgcac gggcttgctt taagacactg aatgagagtc ctaagggtgc ttgcatatct
      361 gacaagtctg aaggctgcta ttctggatct tcaaaagagc tggagcaaag acagagaggt
      421 ggtgctgaag tggcaaaaga cggagcagca cagcactgtg aagacagcag ctgtggacag
      481 agagatcagg cttctagagg acaggacagg gttgggacac atacccagaa tcaggacagc
      541 taccctacac aggtcagcag tcatgacagg cagactgagt ctcagacaca ggaaatgata
      601 agccaacaaa cacaagtgac aggacaggtg gagcagaccc caagaacaga agacaagagt
      661 tggaccagac agaagaggtc agagaggcaa ccacagagta gccaacagac agatgagatc
      721 acaactggat ctacagctca gacccaagca ggtaacttct acacacaggg gtctacctgt
      781 gactataaca gaggaactaa cagccatcac caagacagaa gccatgcaga cagagcttct
      841 acacaacact accagacaca ggcagggtct catactcaga tacacacaca gatggtagaa
      901 caggcctggg ggcagcaaac aggaagtgat agcatccaga cacaggggtc tatctatgac
      961 cagagcactg agactgtgat tcatggccaa gacaggaacc aggcaagcca gagtgttaaa
     1021 gaacaccacc aggcacaggg agagtcatat attcagacac atactcagac aatggaacaa
     1081 ggcaggagcc agcaggcaga aaatagtagc acccagactc atgggtccat gtatggccaa
     1141 aacagagaga ctgagatcca tgggctagaa agcagtcagg cagaacaggt ggggacaaga
     1201 cactaccaga cacaggcagg atcatatacc cagactttgg aacatgatgg gagccagtct
     1261 gcacataaat ttgtggctca agaaaaggaa cgtacacaga caaagccatg catggggcaa
     1321 agctggacac cagtaagcaa ctatgagaca gaagagtcag tgataggagg acaggtccag
     1381 actgagacag acactattat agagaatcac ccaagcccga cagccaggca ggtagagaga
     1441 gtacccacag tggttagaga ggagtgggtc aatgaccaca caagggaaat agtaatccga
     1501 agccaggatc caggtagcct gcactctggt actccttcag ctcagggcca ggatatacca
     1561 cagatggaga agaaaggaat cacagccaag ggactatata cctacttgaa gacagagcag
     1621 ccatgacttt tcccgattcc agctggagtg aggttggcct gccctgccct gccctgccct
     1681 gccctgccct gccctgccct gccctgccct gccatggtac ttcaccagac agccatgatt
     1741 cttcttgttt ggttctttta cagtgatcat ctctacaagg tgatttcttg tcaaaactca
     1801 cctctcttac ctgctgctct cagaaactca cctctcttac ctgatattct cagaaacagg
     1861 aagatgtgga ggaggtcatc tcattgcact gaattccccc caattttcag ggggtttcaa
     1921 agctgtttta tctctggtat ctgtccattg catcaataaa ggcttagaag ctg
//
