LOCUS       NM_025820               3111 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus crooked neck pre-mRNA splicing factor 1 (Crnkl1),
            mRNA.
ACCESSION   NM_025820
VERSION     NM_025820.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3111)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3111)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3111)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 3111)
  AUTHORS   Chung,S., Zhou,Z., Huddleston,K.A., Harrison,D.A., Reed,R.,
            Coleman,T.A. and Rymond,B.C.
  TITLE     Crooked neck is a component of the human spliceosome and implicated
            in the splicing process
  JOURNAL   Biochim Biophys Acta 1576 (3), 287-297 (2002)
   PUBMED   12084575
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL672100.7.
            
            On Apr 29, 2007 this sequence version replaced NM_025820.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004749.1, AK012962.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               AL672100.7         176546-176692       c
            148-300             AL672100.7         174805-174957       c
            301-392             AL672100.7         174238-174329       c
            393-551             AL672100.7         173262-173420       c
            552-718             AL672100.7         172526-172692       c
            719-897             AL672100.7         170113-170291       c
            898-1068            AL672100.7         168768-168938       c
            1069-1260           AL672100.7         167500-167691       c
            1261-1320           AL672100.7         166707-166766       c
            1321-1401           AL672100.7         165836-165916       c
            1402-1641           AL672100.7         163764-164003       c
            1642-1743           AL672100.7         162589-162690       c
            1744-1992           AL672100.7         161732-161980       c
            1993-3111           AL672100.7         159474-160592       c
FEATURES             Location/Qualifiers
     source          1..3111
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 71.28 cM"
     gene            1..3111
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /note="crooked neck pre-mRNA splicing factor 1"
                     /db_xref="GeneID:66877"
                     /db_xref="MGI:MGI:1914127"
     exon            1..147
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..2169
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /note="crooked neck homolog; Crn, crooked neck-like 1"
                     /codon_start=1
                     /product="crooked neck-like protein 1"
                     /protein_id="NP_080096.1"
                     /db_xref="CCDS:CCDS16828.1"
                     /db_xref="GeneID:66877"
                     /db_xref="MGI:MGI:1914127"
                     /translation="MAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELEL
                     LPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARS
                     IYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEE
                     MLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVERARTIYERFVLVHPAVKNW
                     IKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYK
                     YALDRISKQEAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWF
                     DYLRLVESDAEADTVREVYERAIANVPPIQEKRHWKRYIYLWVNYALYEELEAKDPER
                     TRQVYQASLELIPHKKFTFAKMWLYYAQFEIRQKNLPFARRALGTSIGKCPKNKLFKG
                     YIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIERARAIYELAISQ
                     PRLDMPEVLWKSYIDFEIEQEETERTRNLYRQLLQRTQHVKVWISFAQFELSSGKEGS
                     VAKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEDEFGTVSDKERVDKLMPEKVKKR
                     RKVQADDGSDAGWEEYYDYIFPEDAANQPNLKLLAMAKLWKKQQQEREAAEQDPDKDI
                     DESESSSF"
     exon            148..300
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            301..392
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            393..551
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            552..718
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            719..897
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1068
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1260
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            1261..1320
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1401
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1641
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            1642..1743
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1992
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     exon            1993..3111
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2314..2319
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /note="hexamer: AGTAAA"
     polyA_site      2334
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /note="major polyA site"
     regulatory      2741..2746
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
                     /note="hexamer: ATTAAA"
     polyA_site      2773
                     /gene="Crnkl1"
                     /gene_synonym="1200013P10Rik; 5730590A01Rik; crn"
ORIGIN      
        1 gtttgttgtg gctgactctg ttgtgccggc cggttcgaag tgcttttctc aagtccggtt
       61 gtcggccagg atcgctcgag ttccacggct gcagtcatgg cagcctccac ggcggccggg
      121 aaacagcgca ttcctaaagt ggccaaggtg aagaacaagg cgccggccga agtgcagata
      181 acggccgagc agctcctccg agaagctaaa gagagagaac tcgagctcct cccacctcca
      241 cctcagcaga agatcacaga tgaggaagaa ttaaacgatt acaaactccg gaaaaggaag
      301 acttttgaag ataacataag aaaaaatagg actgtgatta gcaactggat aaaatacgca
      361 caatgggagg aaagtctaaa ggaaattcaa agggctcgat ccatatacga gcgtgcttta
      421 gatgtcgact accgaaatat taccctctgg ctgaaatatg cagaaatgga gatgaagaac
      481 cgccaggtca accatgcccg aaacatctgg gaccgtgcca tcacaactct gccacgcgtc
      541 aaccagttct ggtataagta cacatacatg gaggagatgt tgggcaacgt tgctggtgcc
      601 cgccaggtgt ttgagcgctg gatggaatgg cagcctgagg agcaggcctg gcattcctac
      661 atcaacttcg agctgagata caaagaggtg gagcgggccc gcaccatcta tgaacgcttt
      721 gtgctcgtgc accctgctgt gaaaaactgg atcaagtacg caagatttga agagaagcat
      781 gcttactttg ctcatgcgcg gaaagtctac gagagagcgg tggagttttt tggggatgag
      841 catatggacg aacacctcta tgtggccttt gctaaatttg aggaaaacca gaaagaattt
      901 gaaagggtac gagttatcta caaatatgcc ctggatagga tttcaaaaca agaggcccaa
      961 gaactcttta aaaactatac catctttgag aagaagtttg gtgaccggag gggtatagaa
     1021 gacatcatcg tgagcaaacg gaggttccag tatgaagaag aagtgaaggc taatccacac
     1081 aattatgatg catggtttga ttatttacgc ttggtggaaa gtgatgcgga agctgacact
     1141 gtgcgggaag tctatgagag agccattgcc aatgtgccac ccatccagga gaagagacac
     1201 tggaagcgct acatctacct ttgggttaac tatgcactct atgaagagct ggaagccaag
     1261 gatcccgaga gaacaagaca ggtatatcaa gcgtctttgg aactaattcc tcacaaaaag
     1321 ttcacatttg ccaaaatgtg gttatattat gcacagtttg aaataagaca gaaaaatctg
     1381 ccatttgcca gaagagcttt gggaacttcc ataggcaaat gtccgaagaa caagttattc
     1441 aaaggataca tagaactgga actgcagctt cgagaatttg acagatgcag gaagctttat
     1501 gaaaagtttt tggaatttgg acctgaaaat tgtacctcat ggattaagtt tgcagaatta
     1561 gagacaatcc ttggtgatat tgagagagct cgggcaatct atgaattagc catcagccag
     1621 ccacgcttgg atatgccaga ggtactttgg aaatcatata ttgattttga gattgagcag
     1681 gaagaaactg aaagaacacg aaacctttac cgacaattgc ttcagcgaac acagcatgtc
     1741 aaggtatgga tcagttttgc tcagtttgag ttatcgtctg ggaaagaagg aagtgtggct
     1801 aaatgcagac agatttatga agaagctaac aaaaccatga gaaactgtga agaaaaagaa
     1861 gagaggctta tgttgctgga atcctggaga agttttgaag atgaatttgg cacagtatca
     1921 gacaaggaga gagtagacaa actcatgcca gaaaaggtca agaagagaag aaaggtccag
     1981 gccgacgatg ggtctgacgc cgggtgggaa gaatactatg actacatctt cccagaggat
     2041 gctgccaacc agcctaacct caagctcctg gccatggcca agctgtggaa gaaacagcaa
     2101 caggaaagag aagctgccga acaggatcca gataaggaca ttgatgagag tgaatcctca
     2161 tctttttaaa tgttataatt gctttttata aatgaacagt ttagaacttt gactcctaaa
     2221 tgtttttatg tatttactca gtaaggagtt gtttggcatc tttgaattat tttttaaaat
     2281 gctcttgggt ttaactatgg gtgagaaact gcaagtaaaa gaattttttt ctaagttttg
     2341 ttacttgagt ccgagcattt ctagcatttg ctcctattgt ctttgttaga tggagttcat
     2401 gtgcttagca catacgttgg gtcgaactgc agactaaact cagtgttcaa ggtccattct
     2461 ccaggaatag acacaggttt atcatgatgg tgttcatgaa tctgaaactt ttagatttca
     2521 tgtctctaaa accacaaaac tggagtccaa ctctaacacc tccatgtggt ggctgtacgt
     2581 ttccattgat tttcagtttt ctcaaacaag cagtagtatg gtggcacctc attttgatga
     2641 ttccattaga aaaggagtat gctgatgtca atcttgttcc aacagcacac cttcccctgc
     2701 ccctactgcc ttttagcatc atgtgtctac ttctcataga attaaatgga cttgggctag
     2761 ttttctctct gaatatctga acagatttat agtgactgta ttttttgacc ccaagtcttt
     2821 gtcaggaaca ttttagtttg gcttcagttt ttctctcaaa ctagttaagt tttgtagtag
     2881 cttgtttaga aaacaatggc ctgcattcac ggatgctgag gcagtgtcct attggattta
     2941 ttatgtaaat gtctgtgtta agtatgattc accattgcac tactgccagt cccaagcttt
     3001 gtgaattctg cagttatagt tgcctagaaa ctatgtatct cccaacatgc ctcagaatgt
     3061 gtgaattcta acaactgatg tttaacagtt gtcattaaac aacaggagtc c
//
