LOCUS       NM_019936               1171 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus cysteine-rich PDZ-binding protein (Cript), mRNA.
ACCESSION   NM_019936 XM_986437
VERSION     NM_019936.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1171)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1171)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 1171)
  AUTHORS   Leduc,M.S., Niu,Z., Bi,W., Zhu,W., Miloslavskaya,I., Chiang,T.,
            Streff,H., Seavitt,J.R., Murray,S.A., Eng,C., Chan,A., Yang,Y. and
            Lalani,S.R.
  TITLE     CRIPT exonic deletion and a novel missense mutation in a female
            with short stature, dysmorphic features, microcephaly, and
            pigmentary abnormalities
  JOURNAL   Am J Med Genet A 170 (8), 2206-2211 (2016)
   PUBMED   27250922
  REMARK    Review article
REFERENCE   4  (bases 1 to 1171)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 1171)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY123761.1, AK029409.1 and AK004828.1.
            
            On Oct 30, 2009 this sequence version replaced NM_019936.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004828.1, SRR1660815.345472.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                BY123761.1         2-13
            13-575              AK029409.1         1-563
            576-1171            AK004828.1         570-1165
FEATURES             Location/Qualifiers
     source          1..1171
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 56.9 cM"
     gene            1..1171
                     /gene="Cript"
                     /gene_synonym="1200020A08Rik"
                     /note="cysteine-rich PDZ-binding protein"
                     /db_xref="GeneID:56724"
                     /db_xref="MGI:MGI:1929655"
     exon            1..115
                     /gene="Cript"
                     /gene_synonym="1200020A08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..405
                     /gene="Cript"
                     /gene_synonym="1200020A08Rik"
                     /note="cysteine-rich interactor of PDZ3; cysteine-rich
                     interactor of PDZ three; postsynaptic protein Cript"
                     /codon_start=1
                     /product="cysteine-rich PDZ-binding protein"
                     /protein_id="NP_064320.1"
                     /db_xref="CCDS:CCDS29012.1"
                     /db_xref="GeneID:56724"
                     /db_xref="MGI:MGI:1929655"
                     /translation="MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKALTSKK
                     ARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV"
     exon            116..181
                     /gene="Cript"
                     /gene_synonym="1200020A08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            182..236
                     /gene="Cript"
                     /gene_synonym="1200020A08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            237..340
                     /gene="Cript"
                     /gene_synonym="1200020A08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            341..1171
                     /gene="Cript"
                     /gene_synonym="1200020A08Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtagccggaa gaggaagtcg tctccgctgg ggcgttgttg tgtttgggtt gctgctcctg
       61 ctttgccggc tgagggcaca gggacacccc catgtaagga tggtgtgtga aaagtgtgaa
      121 aagaaactcg gcagagttat cactccagac acatggaaag atggtgcccg gaacaccaca
      181 gagagtggtg ggaggaagct gaacgaaaat aaagctttga cttcgaaaaa agcaaggttt
      241 gatccatatg gaaaaaataa gttctccact tgcagaattt gtaaaagttc tgtacaccag
      301 ccaggttctc attactgtca aggctgcgcc tacaaaaaag gcatctgtgc gatgtgtggc
      361 aaaaaggttt tggataccaa aaactacaag cagacttccg tgtagatata ttgatgaaga
      421 tcctgactct ctaggattgt actttgtgct tcaactattc aaggcatagc atgaatggac
      481 gtccatctta caaaataacc tgtgtgaaga tgaatgattc ggcctgaagc agggaagttg
      541 atcagtattg atttgtctgc tctcacaaag ttctgaacag caatgatacg cccagttttc
      601 tgccttaagt ggttgttttc cttgtgagca ttgtactgaa ctagataaga gacaaaatta
      661 atgaataagg tgttcctgac ttctgtacgc actgtctact caacattatc catatgattc
      721 ttacctgatc catgcattta tttatagtta ctgcaaatgt gaaattactg atcctttgct
      781 ctgaacttga catccagacc tcagatttct catttattca caaatgtcac agttcttaga
      841 atgagcagca ccttagttaa gtgcattttc atgagctata aattattgca gagtggttcc
      901 ttagtgacca gtcctgccga aagtctaaga caagttgcat attttactta aatttgctgt
      961 taacactaaa gtccaacatg tgactgagag ccatggggcc caactgtcca ggcactgaag
     1021 ttcagagatg tgcattccgt cagcattatc ttaaattcaa atgaggataa gtttcttctg
     1081 tttcggaatg ctctttgaag caagaaacaa gtctttcctt aacatccctc cacccccgct
     1141 gccactccct cagaaataaa gcaagcaccc t
//
