LOCUS       NM_015800               5995 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus cysteine rich transmembrane BMP regulator 1 (Crim1),
            transcript variant 1, mRNA.
ACCESSION   NM_015800 XM_128751
VERSION     NM_015800.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5995)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5995)
  AUTHORS   Itoh,Y., Sahni,V., Shnider,S.J., McKee,H. and Macklis,J.D.
  TITLE     Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts
            murine cervical corticospinal innervation by distinct
            subpopulations
  JOURNAL   Cell Rep 42 (3), 112182 (2023)
   PUBMED   36934325
REFERENCE   3  (bases 1 to 5995)
  AUTHORS   Song,J.H.T., Ruven,C., Patel,P., Ding,F., Macklis,J.D. and Sahni,V.
  TITLE     Cbln1 Directs Axon Targeting by Corticospinal Neurons Specifically
            toward Thoraco-Lumbar Spinal Cord
  JOURNAL   J Neurosci 43 (11), 1871-1887 (2023)
   PUBMED   36823038
REFERENCE   4  (bases 1 to 5995)
  AUTHORS   Knoedler,J.R., Inoue,S., Bayless,D.W., Yang,T., Tantry,A.,
            Davis,C.H., Leung,N.Y., Parthasarathy,S., Wang,G., Alvarado,M.,
            Rizvi,A.H., Fenno,L.E., Ramakrishnan,C., Deisseroth,K. and
            Shah,N.M.
  TITLE     A functional cellular framework for sex and estrous cycle-dependent
            gene expression and behavior
  JOURNAL   Cell 185 (4), 654-671 (2022)
   PUBMED   35065713
  REMARK    Erratum:[Cell. 2024 Jul 11;187(14):3781. doi:
            10.1016/j.cell.2024.05.045.. PMID: 38810647]
REFERENCE   5  (bases 1 to 5995)
  AUTHORS   Sahni,V., Itoh,Y., Shnider,S.J. and Macklis,J.D.
  TITLE     Crim1 and Kelch-like 14 exert complementary dual-directional
            developmental control over segmentally specific corticospinal axon
            projection targeting
  JOURNAL   Cell Rep 37 (3), 109842 (2021)
   PUBMED   34686337
  REMARK    GeneRIF: Crim1 and Kelch-like 14 exert complementary
            dual-directional developmental control over segmentally specific
            corticospinal axon projection targeting.
REFERENCE   6  (bases 1 to 5995)
  AUTHORS   Glienke,J., Sturz,A., Menrad,A. and Thierauch,K.H.
  TITLE     CRIM1 is involved in endothelial cell capillary formation in vitro
            and is expressed in blood vessels in vivo
  JOURNAL   Mech Dev 119 (2), 165-175 (2002)
   PUBMED   12464430
  REMARK    GeneRIF: CRIM1 has a role in capillary formation and maintainance
            during angiogenesis
REFERENCE   7  (bases 1 to 5995)
  AUTHORS   Leighton,P.A., Mitchell,K.J., Goodrich,L.V., Lu,X., Pinson,K.,
            Scherz,P., Skarnes,W.C. and Tessier-Lavigne,M.
  TITLE     Defining brain wiring patterns and mechanisms through gene trapping
            in mice
  JOURNAL   Nature 410 (6825), 174-179 (2001)
   PUBMED   11242070
REFERENCE   8  (bases 1 to 5995)
  AUTHORS   Georgas,K., Bowles,J., Yamada,T., Koopman,P. and Little,M.H.
  TITLE     Characterisation of Crim1 expression in the developing mouse
            urogenital tract reveals a sexually dimorphic gonadal expression
            pattern
  JOURNAL   Dev Dyn 219 (4), 582-587 (2000)
   PUBMED   11084657
REFERENCE   9  (bases 1 to 5995)
  AUTHORS   Lovicu,F.J., Kolle,G., Yamada,T., Little,M.H. and McAvoy,J.W.
  TITLE     Expression of Crim1 during murine ocular development
  JOURNAL   Mech Dev 94 (1-2), 261-265 (2000)
   PUBMED   10842084
REFERENCE   10 (bases 1 to 5995)
  AUTHORS   Kolle,G., Georgas,K., Holmes,G.P., Little,M.H. and Yamada,T.
  TITLE     CRIM1, a novel gene encoding a cysteine-rich repeat protein, is
            developmentally regulated and implicated in vertebrate CNS
            development and organogenesis
  JOURNAL   Mech Dev 90 (2), 181-193 (2000)
   PUBMED   10642437
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154366.2 and AC103598.6.
            
            On Apr 7, 2010 this sequence version replaced NM_015800.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF168680.1, BC100348.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-852               AC154366.2         127112-127963
            853-1026            AC103598.6         152547-152720       c
            1027-1269           AC103598.6         110247-110489       c
            1270-1390           AC103598.6         109096-109216       c
            1391-1512           AC103598.6         87354-87475         c
            1513-1695           AC103598.6         77156-77338         c
            1696-1893           AC103598.6         74716-74913         c
            1894-2022           AC103598.6         55107-55235         c
            2023-2179           AC103598.6         45956-46112         c
            2180-2301           AC103598.6         44480-44601         c
            2302-2511           AC103598.6         43176-43385         c
            2512-2727           AC103598.6         39563-39778         c
            2728-2949           AC103598.6         35285-35506         c
            2950-3144           AC103598.6         22476-22670         c
            3145-3267           AC103598.6         20345-20467         c
            3268-3458           AC103598.6         17694-17884         c
            3459-5995           AC103598.6         13870-16406         c
FEATURES             Location/Qualifiers
     source          1..5995
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 48.09 cM"
     gene            1..5995
                     /gene="Crim1"
                     /note="cysteine rich transmembrane BMP regulator 1"
                     /db_xref="GeneID:50766"
                     /db_xref="MGI:MGI:1354756"
     exon            1..852
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     CDS             522..3635
                     /gene="Crim1"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; cysteine-rich motor neuron 1 protein; CRIM-1;
                     cysteine rich transmembrane BMP regulator 1 (chordin
                     like)"
                     /codon_start=1
                     /product="cysteine-rich motor neuron 1 protein isoform 1
                     precursor"
                     /protein_id="NP_056615.1"
                     /db_xref="CCDS:CCDS28976.1"
                     /db_xref="GeneID:50766"
                     /db_xref="MGI:MGI:1354756"
                     /translation="MYLVAGGRGLAGCGHLSVSLLGLLLLLARSGTRALVCLPCDESK
                     CEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSIT
                     EYEVGVCEDEDWDDDQLIGFEPCNENLISGCNIINGKCECGTIRTCNNPFEFPRKDMC
                     LSALKRIEEEKPDCSKARCEVRFSPRCPEDSILIEGYAPPGECCPLPSRCVCDPAGCL
                     RKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDSYETQ
                     VRLTADGCCTLPARCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKP
                     ACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCED
                     PIYPLNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMHPVKVPG
                     ECCPVCEEPTYITIDPPACGELSNCSLKEKDCVYGFKLDHNGCRTCQCKIREELCLGL
                     KRACTLDCPFGFLTDVHNCELCQCRPRPKKCRPTMCDKFCPLGFLKNKHGCDICRCKK
                     CPELPCSKICPLGFQQDSHGCLICKCREVPPSAGPPVLSGTCLSMDGHHHKNEESWHD
                     GCRECYCHNGKEMCALITCPVPACGNPTIRSGQCCPSCTDDFVVQKPELSTPSICHAP
                     GGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDDPPQ
                     PSTSHNESVPSYCRNDEGDIFLAAESWKPDACTSCVCVDSAISCYSESCPSVACERPV
                     LRKGQCCPYCLEDTIPKKVVCHFSGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPP
                     LPCAEPIKVEGSCCPMCPEMYVPEPTNVPIEKKNHRGEIDLEVPMWPTPSENDIIHLP
                     RDMGHLQVDYRDNNRLHPGEDSSLDSIVSVVVPIIICLSIIIAFLLINQKKQWVPLLC
                     WYRTPTKPSSLNNQLVSVDCKKGTRVQVDGPQRMLRIAEPDARFSGFYSMQKQNHLQA
                     DNFYQTV"
     exon            853..1026
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1269
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1390
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..1512
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1695
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1696..1893
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1894..2022
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2023..2179
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..2301
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2511
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2512..2727
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2728..2949
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2950..3144
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            3145..3267
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            3268..3458
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            3459..5995
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5960..5965
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Crim1"
                     /note="hexamer: AATAAA"
     polyA_site      5995
                     /gene="Crim1"
                     /note="major polyA site"
ORIGIN      
        1 gggagagagc cgagccgggc acaaggaacg gacgccacgg accttctgct gagccaccgc
       61 gcccactcgg cggctcggga ggcggggacc ggcccggagg ctgcgctgcc gtcgtctttc
      121 cccggcaatc aggagcagcg cggaggacca gaaggagcca ccagcccttc ttcggagcgg
      181 tgcgcagcca ccgccgccgc cagaagtttg ggttgaaccg gagctgccga gaggaaactt
      241 tttttcctct tttccccctc ccgcccggga ggagaaggag gaggagggga agccacccgc
      301 caccgctgcc gctggcgcca acgctcgtgg gctccgggtc ggcgcggccc gcaggggcgg
      361 cgggggcctc gccccgcgag gggaggagcg ccccgggggc ccctagtggg gcacgaggac
      421 cgcgggctgc gggtgcggcg gcggcgcgtg tgccccgcgc aggggagggc gcccgccccg
      481 ctcccggccc gactgcgagg aggaggcggc ggcgcaggag gatgtacttg gtggcggggg
      541 gcagggggct ggccggctgc gggcacctct cggtctcgct gctggggctg ctgctgctgc
      601 tggcgcgctc aggcacccgg gcgctggtct gcctgccctg tgacgagtcc aagtgcgagg
      661 agcctcggag ctgcccagga agcatcgtgc agggcgtctg cggctgctgc tacatgtgcg
      721 cccgccagag gaacgagagc tgcggtggag cctatgggct ccatggagcc tgcgaccggg
      781 ggctgcgctg tgtcatccgc cccccgctca atggcgactc catcaccgag tacgaagtgg
      841 gcgtctgcga agatgaggac tgggatgatg accagctaat aggttttgaa ccctgcaatg
      901 aaaacctcat ctccggctgc aacataatca atgggaaatg cgaatgtggt accatccgaa
      961 cctgcaacaa tccctttgag tttccaagga aggacatgtg cctttcagca ttaaagagga
     1021 tcgaagaaga gaagccagat tgcagcaagg cccgctgtga agtgcggttc tctccacgtt
     1081 gccctgaaga ttccattctg atcgagggct atgctccccc cggggagtgc tgtcctttac
     1141 ccagccgctg cgtgtgcgac cctgcgggct gtctgcgcaa agtctgccag ccaggatacc
     1201 tgaacattct agtgtccaaa gcctcaggga agccgggaga gtgttgtgac ctctatgagt
     1261 gtaaaccagt tttcagcgtg gactgcagca ccgtggagtg cccccctgtc cagcaggccg
     1321 tgtgccccct ggacagctac gaaacgcaag tgcggctcac agcggatggc tgctgtaccc
     1381 tgccagcaag atgcgagtgt ctctctggct tatgtggttt tcccgtttgt gaggtgggat
     1441 ctactccccg aatagtctct cgtggagatg ggacacctgg aaagtgctgt gatgtctttg
     1501 aatgtgttaa tgaaacaaag ccagcctgcg tgttcaacag cgtggagtat tacgacggag
     1561 acatgtttcg aatggacaac tgtcggttct gccgatgcca ggggggtgtc tccatctgct
     1621 tcacggcgca gtgtggggaa ctgaactgcg aaagatacta tgtgcctgag ggggagtgtt
     1681 gccctgtgtg tgaagatccc atctatcctc ttaacaaccc tgctggctgc tatgccaatg
     1741 gccagatccg cgcccacggg gaccggtggc gggaagatga ctgtaccttc tgccagtgta
     1801 tcaacggaga acctcactgc gtggccacgg cctgcgggca gagctgcatg cacccagtga
     1861 aagtgcccgg ggagtgttgc cccgtgtgtg aagaaccaac ctacatcacg attgatccac
     1921 ctgcatgcgg ggagttgtca aactgttctc tgaaggagaa ggactgcgtt tatggcttca
     1981 aactggatca caatggctgt cgaacctgtc agtgcaaaat cagggaggaa ctctgcttag
     2041 gcctcaaaag ggcctgcacc ctggactgtc cctttggctt cctcaccgat gtgcacaact
     2101 gtgaactctg tcagtgccgc ccacggccca agaagtgcag accaacaatg tgcgacaagt
     2161 tttgtccgct tggattcctg aagaataagc atggctgtga catctgtcgg tgtaagaaat
     2221 gtccagagct gccatgcagc aagatctgcc ccttgggctt ccagcaggac agtcatggct
     2281 gtcttatctg caagtgccga gaggtccctc cttcagccgg gccacctgtc ctgtcaggca
     2341 catgtctgtc catggatggc catcatcata agaacgagga gagctggcat gatggttgcc
     2401 gggaatgcta ctgtcacaac ggaaaggaaa tgtgcgctct catcacctgt cccgtgcctg
     2461 cctgcggcaa ccccaccatt cgttccggac agtgctgccc gtcttgcaca gatgactttg
     2521 tagtgcagaa gccggagctc agcacccctt ctatttgcca cgcccccgga ggagagtact
     2581 ttgtggaagg ggaaacttgg aacattgact cctgtacaca gtgcacctgt cacagtggtc
     2641 gagtgctgtg tgagacggag gtgtgcccac cattgctctg ccagaacccc tcccgcaccc
     2701 aggactcctg ctgcccacag tgtacagatg accctcctca gccttccaca tcccataatg
     2761 agagcgtgcc tagctactgc aggaatgatg aaggagatat cttcctggcg gctgagtcct
     2821 ggaagcccga cgcctgcacc agctgcgtgt gcgtggatag cgcaattagc tgctactctg
     2881 agtcttgccc ttccgtggcc tgtgaaagac ctgttttgag gaaaggccag tgttgcccct
     2941 actgcttaga agacacaatt ccaaagaaag tggtgtgtca cttcagtggg aagacctatg
     3001 ctgacgagga acggtgggat attgacagct gcacgcactg ctactgcctg caaggccaga
     3061 ccctctgctc gaccgtcagc tgcccaccgt taccctgtgc cgagcccatc aaggtggaag
     3121 ggagttgctg cccaatgtgc ccagaaatgt atgtgccaga gccaaccaat gtacccattg
     3181 agaagaaaaa tcatcgtggc gagattgacc tggaggtccc catgtggccc accccaagtg
     3241 aaaatgacat catccatctc cctagagata tgggtcacct ccaggtagat tacagagata
     3301 ataacaggct gcatccaggc gaagactcat cactggactc cattgtctcc gttgtggtcc
     3361 ccataataat atgcctgtcc atcataatag ctttcctact catcaaccag aagaagcagt
     3421 gggtaccact gctgtgctgg taccggacac caaccaagcc ttcttccttg aataatcagc
     3481 tggtatctgt ggactgcaag aaaggcactc gagtccaggt ggatggtccc cagagaatgc
     3541 taagaattgc cgaaccagat gctcgattca gtggcttcta cagcatgcag aaacagaacc
     3601 atctacaggc agacaacttc taccaaacgg tgtgaacacg ggcagcagcg ccgatgaggt
     3661 cccgaaagac ggagaaagac gaaaatctgc tctttaaagt aaactaggat ttgcgcactt
     3721 gcttagtgtc ttgtgtcaga ttgcgacttg gtgtccagcg ctaggggctg gactgggatg
     3781 ggctctgtct acagcactgt gcagaacaag cattcccact tggcctcaag ataactgacc
     3841 acatgttttc atagaaccaa agttttaaaa cttgctaaag tatatttgct tgtaagatag
     3901 ctgtagagac atttggggga ggggagaaag agtttggtgg gggaaatggg ttgggagggt
     3961 agtgttggga agaaaaaaaa atggtcagct tggctcgggg agaaagccag taaaaaaata
     4021 aaagcaatct atggcccaga ggaatttctt tttcctgtta ctctcaagac tgttggttgc
     4081 tgcaaaggta gggcctgaat gagcaggatc acaaaaggcc ttgcaaccga gctgccatac
     4141 cacaccagac aagcgcatca gaactctcga tagccatccc aggtctaaag ccacaagttt
     4201 ctatagagtc acagccgcag taggcagtga ggaagccagg gagatggaaa gcaacagttc
     4261 tcgaaagcgg gttcttgagg atgtattcac tttttttgct gctgctgttt tcttccgtgc
     4321 caaccagcca gttcctagga gacacagcag gttgagtagg aacgaggtca cctcttgacc
     4381 tgaccactgg agctttgctc gctacgtgac aggaagggca acggcgaagg acaccaggca
     4441 tttccagggg ctacacttca ttgttccttg ttgttttctt ctgtgctatc attggttgtt
     4501 catagttttg ttaaagctct agcttaagaa gaaacttttg agaaaaagaa aaaaaaggac
     4561 tgtttgggat tttttttcct tattatatac tgattctaca aaatagaaac tacttcattt
     4621 taattgtata ttattcaagc acctttgttg aaactcaaaa aaaaagatgc ctctttaaac
     4681 tttagcaatt ataggaatat ttatgtaact atcttatgct tcaaaaacaa gagtatttgt
     4741 gtgcatgtgt atataatata tatacatata tatttataca catacagttt atgttttcct
     4801 gttgaatgta tttttatgag attttaacga gaacaaaggc agataaacag gcattccata
     4861 gcaatgcttc cgatcactta gggttttttg aataacatga tctcatttac ctgcagttta
     4921 attgcaaagg aaagggtgtg tgtgtgtggg tgggtgggtg tgtgtgtggg tgtgtgtggg
     4981 tgtgtgtgtg tgtgtgtgta catgagcgtg agtgtataca tatggagcaa ccagcagttc
     5041 acatgctatg gaaaggatat tcctttatta atttttttct tcttcatttg gattttcttt
     5101 cacctggttt ccagtttgct cactgaccag aggcaatgat gccagcattg tgtctgcatc
     5161 actaatcagc tcctggattt ttttttcttt tctttcaaac aactgtttga aacaactact
     5221 ggaatattgt ccacaataag ctggaagttt gttgtagctt gcctcaaata taactgactg
     5281 tatgctatag tgttaacttt tcaaacagct cttagcactt ttatactaat gacccactcg
     5341 tgcattgatt ttcctttaaa aatgcttgtt gtgaaagaca cggataccca gtatgcttaa
     5401 tgtgaaaaga agatatgttc tgttttgtaa aggaactttc aagtattgtt gtaaatactt
     5461 ggacagaggt tgctgaactt aaaaaaaatt aatttattat tataatgacc taatttatta
     5521 atctgaagat taaccatttt ttgtcttaga atatcaaaaa gaaaaaggtg ttctagctgt
     5581 ttgcatcaaa ggaaaaaaag atttattatc aaggggcaat atttttatct atttccaaaa
     5641 taaatttgtt aatgatataa tgttactgag atagatttac atcagcctaa ttagaataaa
     5701 attttgttga caatttatcc attcctggca taagagaaaa aaaaaagaac tttatcaaaa
     5761 aaaattgtaa atgcttgctt tttgtttttt ttttttttca atcatgccca tatgaaaata
     5821 ctaacaggat atagggcaag gtgtaaattt tttttattat tttaaagata tgatttatcc
     5881 tgagtgctgt atctattact cttttacttt ggttcctgtt gtgctcttgt aaaagaaaaa
     5941 caaatataat ttcctgaaga ataaaccggg catatagcac ttggagtgca ccaga
//
