LOCUS       NM_011957               2284 bp    mRNA    linear   ROD 15-OCT-2024
DEFINITION  Mus musculus cAMP responsive element binding protein 3-like 1
            (Creb3l1), mRNA.
ACCESSION   NM_011957 XM_001003519
VERSION     NM_011957.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2284)
  AUTHORS   Li,Y., Lin,Y., Guo,J., Huang,D., Zuo,H., Zhang,H., Yuan,G., Liu,H.
            and Chen,Z.
  TITLE     CREB3L1 deficiency impairs odontoblastic differentiation and molar
            dentin deposition partially through the TMEM30B
  JOURNAL   Int J Oral Sci 16 (1), 59 (2024)
   PUBMED   39384739
  REMARK    GeneRIF: CREB3L1 deficiency impairs odontoblastic differentiation
            and molar dentin deposition partially through the TMEM30B.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2284)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2284)
  AUTHORS   Saito,A., Kamikawa,Y., Ito,T., Matsuhisa,K., Kaneko,M., Okamoto,T.,
            Yoshimaru,T., Matsushita,Y., Katagiri,T. and Imaizumi,K.
  TITLE     p53-independent tumor suppression by cell-cycle arrest via CREB/ATF
            transcription factor OASIS
  JOURNAL   Cell Rep 42 (5), 112479 (2023)
   PUBMED   37178686
REFERENCE   4  (bases 1 to 2284)
  AUTHORS   Yamamoto,A., Morioki,H., Nakae,T., Miyake,Y., Harada,T., Noda,S.,
            Mitsuoka,S., Matsumoto,K., Tomimatsu,M., Kanemoto,S., Tanaka,S.,
            Maeda,M., Conway,S.J., Imaizumi,K., Fujio,Y. and Obana,M.
  TITLE     Transcription factor old astrocyte specifically induced substance
            is a novel regulator of kidney fibrosis
  JOURNAL   FASEB J 35 (2), e21158 (2021)
   PUBMED   33150680
  REMARK    GeneRIF: Transcription factor old astrocyte specifically induced
            substance is a novel regulator of kidney fibrosis.
REFERENCE   5  (bases 1 to 2284)
  AUTHORS   Ariyasu,D., Kubo,E., Higa,D., Shibata,S., Takaoka,Y., Sugimoto,M.,
            Imaizumi,K., Hasegawa,T. and Araki,K.
  TITLE     Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly
            Inherited GH Deficiency in Humanized GH1 Mouse Models
  JOURNAL   Endocrinology 160 (11), 2673-2691 (2019)
   PUBMED   31436800
REFERENCE   6  (bases 1 to 2284)
  AUTHORS   Kondo,S., Murakami,T., Tatsumi,K., Ogata,M., Kanemoto,S., Otori,K.,
            Iseki,K., Wanaka,A. and Imaizumi,K.
  TITLE     OASIS, a CREB/ATF-family member, modulates UPR signalling in
            astrocytes
  JOURNAL   Nat Cell Biol 7 (2), 186-194 (2005)
   PUBMED   15665855
  REMARK    GeneRIF: Our results reveal pivotal roles for OASIS in modulating
            the unfolded protein response in astrocytes, and the possibility
            that cell type-specific UPR signalling also exists in other cells
REFERENCE   7  (bases 1 to 2284)
  AUTHORS   Hikake,T., Mori,T., Iseki,K., Hagino,S., Zhang,Y., Takagi,H.,
            Yokoya,S. and Wanaka,A.
  TITLE     Comparison of expression patterns between CREB family transcription
            factor OASIS and proteoglycan core protein genes during murine
            tooth development
  JOURNAL   Anat Embryol (Berl) 206 (5), 373-380 (2003)
   PUBMED   12684764
  REMARK    GeneRIF: In mice, the OASIS gene may be related to proteoglycan
            expression and play a role in the differentiation of the
            odontoblast and cells in inner enamel epithelium.
REFERENCE   8  (bases 1 to 2284)
  AUTHORS   Nikaido,T., Iseki,K., Mori,T., Takaki,H., Yokoya,S., Hagino,S.,
            Takeda,J., Zhang,Y., Takeuchi,M., Kikuchi,S. and Wanaka,A.
  TITLE     Expression of OASIS, a CREB/ATF family transcription factor, in CNS
            lesion and its transcriptional activity
  JOURNAL   Brain Res Mol Brain Res 108 (1-2), 129-138 (2002)
   PUBMED   12480185
  REMARK    GeneRIF: Data suggest that OASIS protein positively regulates gene
            transcription in a subset of reactive astrocytes, and may influence
            the reaction of injured central nervous system tissues [OASIS
            protein].
REFERENCE   9  (bases 1 to 2284)
  AUTHORS   Nikaido,T., Yokoya,S., Mori,T., Hagino,S., Iseki,K., Zhang,Y.,
            Takeuchi,M., Takaki,H., Kikuchi,S. and Wanaka,A.
  TITLE     Expression of the novel transcription factor OASIS, which belongs
            to the CREB/ATF family, in mouse embryo with special reference to
            bone development
  JOURNAL   Histochem Cell Biol 116 (2), 141-148 (2001)
   PUBMED   11685542
REFERENCE   10 (bases 1 to 2284)
  AUTHORS   Honma,Y., Kanazawa,K., Mori,T., Tanno,Y., Tojo,M., Kiyosawa,H.,
            Takeda,J., Nikaido,T., Tsukamoto,T., Yokoya,S. and Wanaka,A.
  TITLE     Identification of a novel gene, OASIS, which encodes for a putative
            CREB/ATF family transcription factor in the long-term cultured
            astrocytes and gliotic tissue
  JOURNAL   Brain Res Mol Brain Res 69 (1), 93-103 (1999)
   PUBMED   10350641
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ951890.1, BC016447.1 and CV677746.1.
            
            On Nov 8, 2006 this sequence version replaced NM_011957.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC016447.1, AK142368.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                BQ951890.1         328-352
            26-1726             BC016447.1         1-1701
            1727-2163           BC016447.1         1703-2139
            2164-2164           CV677746.1         57-57               c
            2165-2284           BC016447.1         2141-2260
FEATURES             Location/Qualifiers
     source          1..2284
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 50.63 cM"
     gene            1..2284
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /note="cAMP responsive element binding protein 3-like 1"
                     /db_xref="GeneID:26427"
                     /db_xref="MGI:MGI:1347062"
     exon            1..167
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1628
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /note="old astrocyte specifically induced substance;
                     cAMP-responsive element-binding protein 3-like protein 1;
                     BBF-2 homolog"
                     /codon_start=1
                     /product="cyclic AMP-responsive element-binding protein
                     3-like protein 1"
                     /protein_id="NP_036087.2"
                     /db_xref="CCDS:CCDS38181.1"
                     /db_xref="GeneID:26427"
                     /db_xref="MGI:MGI:1347062"
                     /translation="MDAVLEPFPADRLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFV
                     ENMEDFSNDLFSSFFDDPVLDEKSALLDMELDSPAPGIQAEHSYSLSGDSAPQSPLVP
                     VKMEDTTQDVEHGAWALGNKLCSIMVKQEQSPELPVDPLAASSAMAAAAAMATPPLLG
                     LSPMPRLPIPHQAPGEMTQLPVIKAEPPEMSQFLKVTPEDLVQMPPTPPSSHGSDSDG
                     SQSPRSLPPSSPVRPMARSSTAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYP
                     IPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETYTSENNELWK
                     KVETLETANRTLLQQLQKLQTLVTSKISRPYKMAATQTGTCLMVAALCFVLVLGSLVP
                     CLPAFSSGSMTVKEDPIAADSVYAASQMPSRSLLFYDDGAGSWEDGRGALLPVEPPEG
                     WELKPGGPAEQRPQDHLRHDRADSIHETTKYLRETWPEDTDDNGTSPNFSHPKEWFHD
                     RDLGPNTTIKLS"
     exon            168..396
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            397..581
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            582..660
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            661..818
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            819..968
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1027
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1096
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1196
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1323
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1591
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     exon            1592..2271
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2242..2247
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /note="hexamer: ATTAAA"
     polyA_site      2271
                     /gene="Creb3l1"
                     /gene_synonym="Oasis"
                     /note="major polyA site"
ORIGIN      
        1 ggggttcgcc gccgccctgg agtgaggaaa gcgcagcccg aaggggtccc ctggaacccg
       61 gcgcgatgga cgccgtcttg gaacctttcc cggccgacag gctgttcccg ggatccagct
      121 tcctggactt gggagacctg aatgagtcgg atttcctcaa caatgcgcac ttcccggagc
      181 acctggacca ctttgtggag aacatggagg acttctccaa tgacctgttc agcagtttct
      241 ttgatgaccc tgtgctggac gagaagagtg ctctgctgga catggaactg gactcccccg
      301 ctccaggcat ccaggctgag cacagctact ccctgagtgg ggattctgca ccccagagcc
      361 cccttgtgcc tgtcaagatg gaggacacca ctcaagatgt ggaacacgga gcgtgggccc
      421 tgggaaacaa gctgtgctcc atcatggtga agcaggagca gagcccggag ctgcctgtag
      481 atcccctggc tgcctcctct gccatggctg ctgccgccgc catggccacc ccaccactgc
      541 tgggcctcag ccccatgccc cggctgccca tccctcacca ggccccagga gaaatgactc
      601 agctgccagt gatcaaagca gagcccccag aaatgagcca gtttctcaaa gtgacaccag
      661 aggacctcgt acagatgcct ccaacacccc ccagcagcca tggcagtgac agtgacggct
      721 cccagagtcc ccgctctctt cccccctcca gccctgtccg gcccatggcc cgctcctcca
      781 cggccatttc cacctctccg ctcctcactg cccctcacaa actgcagggg acatcagggc
      841 cactgctctt gacagaagag gagaagcgga ccttgatcgc ggagggttac cctatcccca
      901 ccaagctccc cctcaccaag gctgaggaga aggccttgaa gagagtacgc aggaaaatta
      961 agaacaagat ttctgcccag gagagccgcc gcaagaagaa ggagtatgtg gaatgtctag
     1021 aaaagaaggt ggagacatat acatcagaga acaatgagct gtggaagaaa gtggaaaccc
     1081 tagagactgc caacaggacc ctgctccagc agctgcagaa actccagact ctggtcacca
     1141 gcaagatctc cagaccgtac aagatggcag ccacgcagac cggcacctgc ctcatggtgg
     1201 cagccttgtg cttcgttctg gtgctgggct cccttgtgcc ctgccttcct gcattctctt
     1261 ccggctcaat gactgtgaaa gaagacccta tcgcagctga cagtgtctat gcagccagtc
     1321 agatgccttc ccgaagccta ctgttctacg atgatggggc aggctcatgg gaagatggcc
     1381 gaggtgctct actgcctgtg gagcccccag aaggctggga gctcaaaccc gggggtccag
     1441 cagagcagag gccccaggac cacctccgac atgaccgtgc agacagcatc catgagacca
     1501 ccaagtactt gagagagacc tggccagagg acactgatga caacggcacc agccccaact
     1561 tctcccaccc caaggagtgg ttccatgaca gggatctggg ccccaacacc accatcaaac
     1621 tctcctaggc cactccaaga cccaggacac aggacggaca ccctggcacc cagaagaggc
     1681 gttctcttgc tcgatgaccc agatccagct catacccctg ccccccgggt ccctgtagta
     1741 gctggggacg ctctatgtcc ccagacactt ggactgctcc cctgggctga ccactccgtt
     1801 cccacctttc cctcctacca ctatccgtcc tcctccgata aaccactcac tgggctaccc
     1861 gtttccttcc catagtgacc aacgcaacca ctgttcctgg ccccctcata cacaaacaca
     1921 caagcagaca tacacacaca aacacacacc cccatctcct actgtacaga gaccaagaac
     1981 agaaatcgtt tgtaaataat gaaccttatt ttttattatt gtcaatcccc taagatattg
     2041 tattttacaa atctccctcc cgtcacctct cccttatttt gtattttatg aagttagtgc
     2101 gggctttgct accccttggc ctggggaaga gggacacccc accctcacca ggcctctccc
     2161 tgccgctgcc caagctgctg ggccttttta atttgccaaa ctgctcctcc accagctcag
     2221 cacatgcttt aagaaggcaa aattaaaaaa aaaaaaaaga ttcagcatca aaaaaaaaaa
     2281 aaaa
//
