LOCUS       NP_001390494            1285 aa            linear   ROD 01-MAY-2025
DEFINITION  protein cramped-like [Mus musculus].
ACCESSION   NP_001390494 XP_006524765
VERSION     NP_001390494.1
DBSOURCE    REFSEQ: accession NM_001403565.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 1285)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 1285)
  AUTHORS   Mendez-Frausto,G., Uresti-Rivera,E.E., Godina-Gonzalez,S.,
            Portales-Perez,D.P., Gonzalez-Amaro,R. and Garcia-Hernandez,M.H.
  TITLE     Expression of mBD4, mBD3 and CRAMP during type II collagen-induced
            arthritis/CIA and their association with inflammation and
            bone-remodeling markers
  JOURNAL   Exp Mol Pathol 123, 104689 (2021)
   PUBMED   34592200
  REMARK    GeneRIF: Expression of mBD4, mBD3 and CRAMP during type II
            collagen-induced arthritis/CIA and their association with
            inflammation and bone-remodeling markers.
REFERENCE   3  (residues 1 to 1285)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   4  (residues 1 to 1285)
  AUTHORS   Kargul,G.J., Nagaraja,R., Shimada,T., Grahovac,M.J., Lim,M.K.,
            Nakashima,H., Waeltz,P., Ma,P., Chen,E., Schlessinger,D. and
            Ko,M.S.
  TITLE     Eleven densely clustered genes, six of them novel, in 176 kb of
            mouse t-complex DNA
  JOURNAL   Genome Res 10 (7), 916-923 (2000)
   PUBMED   10899141
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154229.1.
            
            On Apr 1, 2022 this sequence version replaced XP_006524765.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.262694.1,
                                           SRR14777534.1060376.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1285
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.53 cM"
     Protein         1..1285
                     /product="protein cramped-like"
                     /note="hematological and neurological expressed 1-like
                     protein; Crm, cramped-like; cramped chromatin regulator
                     homolog 1"
                     /calculated_mol_wt=136990
     Region          1..161
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6PG95.3)"
     Region          125..>205
                     /region_name="DUF601"
                     /note="Protein of unknown function, DUF601; pfam04642"
                     /db_xref="CDD:282493"
     Site            304
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q96RY5; propagated from
                     UniProtKB/Swiss-Prot (Q6PG95.3)"
     Region          <441..619
                     /region_name="PHA03309"
                     /note="transcriptional regulator ICP4; Provisional"
                     /db_xref="CDD:165564"
     Region          456..519
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6PG95.3)"
     Region          579..673
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6PG95.3)"
     Region          766..843
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6PG95.3)"
     Region          994..1055
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6PG95.3)"
     Region          1068..1107
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6PG95.3)"
     Region          1132..1172
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6PG95.3)"
     Site            1284
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q96RY5; propagated from
                     UniProtKB/Swiss-Prot (Q6PG95.3)"
     CDS             1..1285
                     /gene="Cramp1"
                     /gene_synonym="5830477H08Rik; Cramp1l; mKIAA1426; Tce4"
                     /coded_by="NM_001403565.1:279..4136"
                     /db_xref="GeneID:57354"
                     /db_xref="MGI:MGI:1930190"
ORIGIN      
        1 mtvklgdags geeglkklgk rtadeesldg egpggadaad ssstkrdgqt prasgapapp
       61 rglptpsppq gspqdqhhfl rssvrpqskr prkdapcalg sggasgsgpr gkgsdggass
      121 sgnvsgatpa tpaggsrsss rnigssgpek eegkkvrrqw eswstedknt ffeglyehgk
      181 dfeaiqnnia lkykkkgkpa smvknkeqvr hfyyrtwhki tkyidfdnvf srglkkssqe
      241 lyglicygel rkkiggcmdd knatklneli qvgattvryk grnlrikapm cralkklcdp
      301 dglsdeedqk pvrlplkvpv elqprnnhaw arvqslaqnp rlrmivelhr kvsslieflk
      361 qkwalhevri rktleerqlq gsstvqtqek valhlfpgen ctltplpgva rvvhskafct
      421 vhwqeggrck qgtkdihslp paqilgiqsg qgiargqlkc qrssaegkgg grllptadas
      481 qssgesspes apaegaapsl sspdapdrph glqdsgphle ktpvtalavg rdspiqesga
      541 lpcpcgqppd ledelslldp fprylkscqd liipeqcrra dtrsgrehpp lgsvaspetl
      601 tpssgavads appgldpqpg tdhqpdtrlq sdictkelan asseesqekg spsehlssqg
      661 qpatrpskev pasqlaqqlr eegwslqtse sltlaevylm mgkptklqle ydwlavlgpe
      721 sqaptaqgqt alsrsspsal hqqrllscll rlistevhpk mafeantast asvrptqeeq
      781 sttppgkvvt insrsprcsr npstlrsnkt fpsasapcsp glrnpprpll vagpsstgss
      841 dsdgglfavp ttlppnsrhg klfspskeae ltfrqhldsi siqsdffspk pkklrkrhlr
      901 kplvvqrtll prpsenqshn vcsfsilsns piagrgwfrp iqssltkaal srpivpkvlp
      961 sqatshlpsa idlaaqsagi ipgsplpild tdgssgispl sseqattais gqgdtgphqn
     1021 rdpvtavrgt ndpfisvtrp eqepmtdgfq gspaltlpel skanlqngls iplpssesss
     1081 trlsppnvsa lldislpgpp edvlsqgepa tqisdsiiei aissgqyseg vplspaklng
     1141 sdsskslpsp ssspqpnwia spthdpqwyp sdsadsslss lfasfispek srkmlpttvg
     1201 ansgtsllgp slldgnsrds fvsrsladva evvdsqlvcm mnensidyis rfndlaqels
     1261 itepgrrevl fdgggggnpv gdlsq
//
