LOCUS       NM_001025103            1687 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus calcium release activated channel regulator 2B
            (Cracr2b), mRNA.
ACCESSION   NM_001025103 XM_486022
VERSION     NM_001025103.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1687)
  AUTHORS   Carrasco,S. and Meyer,T.
  TITLE     Cracking CRAC
  JOURNAL   Nat Cell Biol 12 (5), 416-418 (2010)
   PUBMED   20442700
REFERENCE   2  (bases 1 to 1687)
  AUTHORS   Srikanth,S., Jung,H.J., Kim,K.D., Souda,P., Whitelegge,J. and
            Gwack,Y.
  TITLE     A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that
            stabilizes CRAC channels in T cells
  JOURNAL   Nat Cell Biol 12 (5), 436-446 (2010)
   PUBMED   20418871
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC048916.1.
            
            On Apr 28, 2009 this sequence version replaced NM_001025103.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048916.1, BC098333.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1687              BC048916.1         1-1687
FEATURES             Location/Qualifiers
     source          1..1687
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 86.82 cM"
     gene            1..1687
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /note="calcium release activated channel regulator 2B"
                     /db_xref="GeneID:213573"
                     /db_xref="MGI:MGI:2446129"
     exon            1..96
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
     exon            97..285
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..1308
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /note="EF-hand calcium binding domain 4A"
                     /codon_start=1
                     /product="EF-hand calcium-binding domain-containing
                     protein 4A"
                     /protein_id="NP_001020274.2"
                     /db_xref="CCDS:CCDS22016.1"
                     /db_xref="GeneID:213573"
                     /db_xref="MGI:MGI:2446129"
                     /translation="MASPGLPGSGEGQEGEETTGVSARHGVEVLQQAQELFLLCDKDA
                     KGFITRQDLQGLQSDLPLTPEQLEAVFESLDQAHTGFLTAREFCLGLGKFVGVESAPG
                     GSPLRTSEETFESGTGGSLEEEEEDVETFYTSLEKLGVARVLGEQWAVRTLWVGLQRE
                     RPELLGSLEEVLMRASACLEAAAREREGLEQALRRRESEHEREVRGLYEELEQQLGEQ
                     RHRRQSQNLPREEQRGHLELELQTREQELERAGLRQRELEQQLQARAAEQLEAQAQHI
                     QLQRAYEAIRAQLDQAQEQLSRLEGEAQGRQEQTQRDVVAVSRNMQKEKLSLLRQLEL
                     LRELNLRLRDERDACETKLLGSSHRKALAIAHKPGPIYCCCCCGWARPPRRGSGHLPS
                     AR"
     exon            286..397
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
     exon            398..560
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
     exon            561..707
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
     exon            708..798
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
     exon            799..891
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1058
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1130
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1687
                     /gene="Cracr2b"
                     /gene_synonym="6330520A15Rik; Cracr2a; Efcab4; Efcab4a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcctgtccc atacagcaag cctgttgtgg ttctgcttga gacgcacagg gcccccagcg
       61 cctctgcagc ctgtgatagc caggccagct tttcagcacc tccaagagcc aaggctcgct
      121 cctatggcca gccctgggct gcctggatct ggggagggcc aggagggaga ggagacaaca
      181 ggggtctcgg caaggcatgg agtagaggtg ctgcagcagg cccaggaact cttcctacta
      241 tgcgacaagg atgccaaggg cttcatcact cgtcaggatc tgcagggtct gcagagtgat
      301 cttccactta cgcctgaaca gctggaggct gtatttgaaa gtctggacca ggcccacact
      361 ggcttcctca cagcccggga gttctgtcta ggcctgggga agtttgtggg ggtggagtcg
      421 gccccaggtg ggtccccctt gaggacttct gaggaaacct ttgagtcggg cacagggggc
      481 tctctggagg aggaggagga ggatgttgag acattctaca cttccttgga gaagctagga
      541 gtggcccggg tcctgggcga gcaatgggct gtgagaaccc tctgggtcgg gctgcagcgc
      601 gagcgacctg agctgttggg ctctctagag gaagttctga tgcgcgcatc ggcctgcctg
      661 gaggcggcgg cccgggaacg cgaaggtctt gagcaagcgc tgcgacggcg ggagagtgaa
      721 cacgagaggg aggtgcgcgg actgtatgaa gaactggagc agcagctcgg ggagcagcga
      781 caccgcaggc agagccagaa cctaccccgg gaggaacaga ggggccacct ggagctggag
      841 ctgcagaccc gtgagcagga gttggagcgc gcaggcctga ggcagcggga gctggaacag
      901 cagctgcagg cccgggctgc agaacagcta gaggcacagg cccagcacat ccagctgcag
      961 agggcctatg aggccatacg ggcacagctg gaccaggccc aagagcagct cagtcgactg
     1021 gagggcgaag cacagggtcg gcaggagcaa acccaaagag atgtggttgc tgtctccagg
     1081 aatatgcaga aagagaaact cagcctccta aggcagctgg agctgctgag ggagctgaat
     1141 ctgaggcttc gagatgagag agatgcctgt gagaccaagc tgctgggcag tagccacagg
     1201 aaggctctag ctattgccca caagcccgga cccatctact gctgctgctg ctgtggctgg
     1261 gctcggcccc ccagacgagg ctctggccat cttcctagtg cccgatgacc agccccgagt
     1321 gactcacttc cctatccaga ggactgcccc taggagggac tggtcttggt ggcggatact
     1381 tgctaagtgt gtggctctac ccagaaggca tcccatgcct gaaggagcta acctcagagt
     1441 agtcaaggcc ttcagtcctt cagtctttat cctgtcttcc ttttttttgg gggggggggt
     1501 ttcgagacag ggtttctctg tgtagccctg gctgtcctgg aactcattct gtagaccagg
     1561 ctgtcctcga actcagaaat ccgcctgcct ctgcctcccg agtgctggga ttaaaggcgc
     1621 gtgtgccacc acgcccggct atcctgtctt ccttaatctt tgtctgaagg accaataaag
     1681 gccattg
//
