LOCUS       NM_001403619            4814 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus capping protein inhibiting regulator of actin like
            (Cracdl), transcript variant 1, mRNA.
ACCESSION   NM_001403619 XM_006496296
VERSION     NM_001403619.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4814)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4814)
  AUTHORS   Snider,P.L., Snider,E., Simmons,O., Lilly,B. and Conway,S.J.
  TITLE     Analysis of Uncharacterized mKiaa1211 Expression during Mouse
            Development and Cardiovascular Morphogenesis
  JOURNAL   J Cardiovasc Dev Dis 6 (2), 24 (2019)
   PUBMED   31234534
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4814)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4814)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   5  (bases 1 to 4814)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123068.4 and AC140321.3.
            
            On Apr 1, 2022 this sequence version replaced XM_006496296.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10662773.1381436.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-255               AC123068.4         86005-86259         c
            256-693             AC140321.3         201789-202226       c
            694-773             AC140321.3         170008-170087       c
            774-942             AC140321.3         163308-163476       c
            943-1078            AC140321.3         157263-157398       c
            1079-1240           AC140321.3         156768-156929       c
            1241-1450           AC140321.3         153664-153873       c
            1451-3758           AC140321.3         149208-151515       c
            3759-3946           AC140321.3         139928-140115       c
            3947-4091           AC140321.3         138784-138928       c
            4092-4814           AC140321.3         137124-137846       c
FEATURES             Location/Qualifiers
     source          1..4814
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 15.57 cM"
     gene            1..4814
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /note="capping protein inhibiting regulator of actin like"
                     /db_xref="GeneID:72097"
                     /db_xref="MGI:MGI:1919347"
     exon            1..255
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            256..693
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            694..773
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             704..4234
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="CRACD-like protein isoform 1"
                     /protein_id="NP_001390548.1"
                     /db_xref="GeneID:72097"
                     /db_xref="MGI:MGI:1919347"
                     /translation="MISTRVMDIKLREAAEGLGEDGAGKKKSKFKTFKKLFGKKKRKE
                     SPSPTGNSAWKQNPAKSEVIAVEESGPVYDSEDELEESRGTMGSRALSHDSIFFPESG
                     QDPARPVRVFSQENVCDRIKALQLKIQCNVKMGPPPPGGLPIKRAEETGMSSEDDGLP
                     RSPPEMSLLHDVGPGTTIKILVSSSRPQSPDHMSDASISSRTLDGSLAPVVDFSHPPE
                     FSSCLDNSAAKHKLLVKPRNQRSSKLRRLSSRAQSECLSDLSWTLDEEDYEEKPLLHV
                     SMEETPDARQRDLIPGRRPEFGGPATFLSPGGACARRARLQHSMAVSASMEEGGCPRD
                     EPSSLPATPEVTEPMVVSVPSLESPSLPESSPNHILHSKSQKEELSPGGLCPLVESTS
                     EEAPCGSGVAETPLSTDVPERDMGPSKEGSAPPEGDPAFSERHMAFPGGGSIPPEGNT
                     TPHKGVMEPPERDMSPSKDNMAPPKRIIAPPERDMLPSEGDVAPPKRIMAPPERDMSP
                     PEGDVAPPKKIMAPPERDMSPPEGDVAPPKKIMAPPERDMSPPEGDVAPPKKIMAPPE
                     RDMSPSEGDVAPPKKIMAPPERDMSPPEGDVAPPKKIMAPPERDLSPSEGDVAPPKRI
                     MAPPERDMSPFKGDMAPPKGIMEPPNRDTSLPKGDTPPPETITDTNLETPSDTERQDQ
                     SVQKEEELTLVVVPRPEGVGTESSTAPAPSPPVPKSCLKHKALVTSGSPAESPLKEPG
                     PAVQDKAVVPPARPRPTQAATSGGPERTALGRKNERSAEPQRSSVKRFSVTSSRARAR
                     VSGSRLPEYSAHVPAGGRAPLLRSGLAWKSEAALDDLQVLPKPQDRKTMGGDPQNSGD
                     VGAGQAGPGKSPQEAEPCASSVQEPANGEDQSPFPVKLRSTSLSLKYRDSSAQEAKAI
                     KRYSAEVRLEKGGLALLPKDEQSHVGAAPALRGSRSPNGQGKGKTRSPEQPGTKPPLP
                     RKPLLPSLTLPYPPTGLDTSPGESERLIPVILPPEPRKEKLSNQGAEKGQPPAATGPG
                     ADGQPTPPWITMARQKRRGAPDLPVNQEEKPGSRILKTETGKQAKVAERAQESVKQGD
                     FVRSKSFLMTPAKPAVTQRQGSKLNLKEGLQRGISLSHQNLAAQAAATTEKELHQLKR
                     ASYASTDQPSWMELARKKSQAWSDMPQIIK"
     exon            774..942
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1078
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1240
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1450
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..3758
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3759..3946
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3947..4091
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4092..4814
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4795..4800
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4814
                     /gene="Cracdl"
                     /gene_synonym="2010300C02Rik"
                     /note="major polyA site"
ORIGIN      
        1 gagtcgggag ccgggagcgc gcgcccagcg cagggccagc gcggccgccc gagggtcgcg
       61 cccgcgtccg cgtccatccc ccggccgcag accccgcgct acccgcgccc taccgccacc
      121 tgctgcgcgg cgccgccggc cctcgacgct gcggccgggg gtcagggtgc accccggcag
      181 agcagccccc gcttgtcccc gcggactgag cccttcccgg cacgctcgcc aaacacggcc
      241 acgctccagt gccaggtgct gcctactgtg tgctgaatag gggctgaaat tccacctcag
      301 ctggccttac ttgacctcca gtggctcaca gggaaagcat tgtgtgtggg agcagaagcc
      361 ttggacatcg aactgagcct gcctcaacct ggtccacttg tgacttggat ccatcgccct
      421 tactgtcccc tttctgggtt ggaaagcatc ccgcccttcc ctgcagactc taggttctgt
      481 gtgaagagca gcgcttccag ggaaacccaa agcctgcact gtaagaagca actctcagaa
      541 tggactgggt caattctgag ggcctcctat ctcttctcca gaggtagtgc tccctgattc
      601 ccaccagaca gattcctgct ggacacggcg ggcttccgag cctgcatgag gcatgcactg
      661 aattcgcagc agcagcagtt gcttgtctct cagtgacccg gacatgattt ccacgagggt
      721 gatggacatt aaacttcggg aggctgccga aggccttggg gaagatggtg caggaaagaa
      781 aaagtcgaaa tttaaaactt ttaagaagct gtttgggaag aagaagagaa aggaatcccc
      841 ctcacccaca ggaaacagcg cctggaagca aaatccggcc aagagcgagg tcattgccgt
      901 tgaggagtcg gggcccgtgt atgactctga agatgagctg gaggagtcca ggggtactat
      961 gggcagccgg gccctctccc acgacagtat tttctttcct gaatcgggac aggaccctgc
     1021 tcggcccgtg cgggtgttct cccaagaaaa tgtgtgcgac cggatcaagg ctttgcagtt
     1081 aaagatacaa tgtaacgtga agatggggcc accgcctcca ggaggccttc ctatcaagcg
     1141 ggcagaggaa accggcatga gttctgagga tgacggactg ccccgcagcc ccccagagat
     1201 gtccctgctg cacgatgtgg gtccaggcac aactataaag atcctagtgt cctcgtcccg
     1261 gccacagtct cccgaccaca tgagcgatgc ctccatctcg tctcggacct tggatggtag
     1321 cctagctcct gtggttgact tcagccaccc tccagaattc tcttcctgcc tggacaactc
     1381 tgcagctaaa cacaaactcc tggtgaagcc ccgcaaccag cgatcaagta aactgaggcg
     1441 gctgtcttcg agggcgcagt ctgagtgcct gagtgacctg tcgtggaccc tagatgagga
     1501 agactatgag gagaagccat tgcttcatgt cagcatggaa gaaaccccgg acgctaggca
     1561 gcgggatttg ataccaggca gaaggcctga gtttggggga cctgcaacct ttctgtcacc
     1621 tgggggggcc tgtgccaggc gtgctcgcct acagcacagc atggcagtca gtgccagcat
     1681 ggaggaggga ggctgtccta gagatgaacc ctcaagcctt ccagctacgc cagaagttac
     1741 tgagcccatg gtggtctcag tcccaagctt ggagtcccca tctctgccag aaagttctcc
     1801 aaaccatatt ctccatagta agagccagaa ggaagagctg tcccctggag gcctgtgtcc
     1861 cctagtggag agtacatcag aggaggctcc ttgtggttct ggagttgcag aaacccctct
     1921 atctactgat gtccctgaga gggacatggg accttccaag gagggctctg cacctcctga
     1981 gggagaccca gcattttctg aaagacacat ggcattccct ggagggggta gcatacctcc
     2041 tgaaggaaac acaacacctc acaagggtgt catggaacct cccgagagag acatgtcacc
     2101 ttccaaggac aacatggcac ctcccaagag gatcatagca cctccagaga gagacatgtt
     2161 accttctgag ggagatgtgg cacctcccaa gaggatcatg gcacccccag agagagacat
     2221 gtcacctccc gagggagatg tggcacctcc caagaagatc atggcacccc cagagagaga
     2281 catgtcacct cccgagggag atgtggcacc tcccaagaag atcatggcac ccccagagag
     2341 agacatgtca cctcccgagg gagatgtggc acctcccaag aagatcatgg cacccccaga
     2401 gagagacatg tcaccttccg agggagatgt ggcacctccc aagaagatca tggcaccccc
     2461 agagagagac atgtcacctc ccgaaggaga tgtggcacct cccaagaaga tcatggcacc
     2521 cccagaaaga gacttgtcac cttctgaggg agatgtggca cctcccaaga ggatcatggc
     2581 acccccagag agggacatgt cacctttcaa gggtgacatg gcaccaccca aaggaatcat
     2641 ggagcctcct aatagggaca catcacttcc aaagggagac acaccacctc ctgagactat
     2701 cactgatacc aacttggaga caccttcaga tacagagaga caggaccaaa gtgtccagaa
     2761 ggaagaggag ctgaccctgg tggtggtacc caggcctgag ggagtgggga cagagtcttc
     2821 cacagcccct gccccaagcc ctccagtacc caagagctgc ctgaagcaca aggccttggt
     2881 caccagtggg tcccctgcag agtctcctct gaaagagcct ggcccagcag tccaagacaa
     2941 agcagttgtg cctcccgccc gccccaggcc tacacaggct gcaacctcag gaggtccaga
     3001 gagaacagcc ctggggagaa agaacgagcg gagtgcagag ccacagcgca gcagcgttaa
     3061 gaggttttct gtgacctcca gcagggcacg tgcccgtgtc agcggctctc gccttccgga
     3121 gtattctgca catgtgcctg cagggggccg agcacccttg ctgcggagtg gccttgcctg
     3181 gaagagtgag gcagcacttg acgaccttca ggtgctgcca aagccacagg accggaagac
     3241 aatgggtggt gaccctcaaa actcagggga tgtgggggcc ggccaggcag gaccgggcaa
     3301 gagcccccag gaagctgagc catgtgcctc ctctgtgcag gagccagcca atggggagga
     3361 ccagagcccc ttcccagtca agctgcggtc cacctcactc tcacttaaat acagagacag
     3421 ctctgcccaa gaggccaaag ccatcaagag gtacagcgcc gaagtcaggt tggagaaagg
     3481 aggcctggct ctgcttccca aagatgaaca gagccacgtc ggggcagctc ctgcactgcg
     3541 aggctccagg tcccccaacg ggcaagggaa aggaaagacc aggtctcctg agcagccagg
     3601 taccaagcca cccctgccca ggaagccact tctgccgagc cttaccttgc catacccacc
     3661 cacaggcctg gataccagcc ctggggagtc tgagagactc ataccggtca tcctgcctcc
     3721 cgagcccagg aaggagaaat tgtccaatca gggagctgaa aagggtcagc ctcctgcggc
     3781 tacaggtcct ggggctgatg ggcaacccac cccaccctgg atcaccatgg cccggcagaa
     3841 gagaagagga gccccagacc tgcccgtcaa ccaggaagag aaacctgggt cgaggatcct
     3901 aaagacagaa actgggaagc aagccaaggt ggccgagaga gcccaggagt ctgtgaagca
     3961 gggtgacttc gtccggagca aatctttcct gatgacccct gcaaagcctg ctgtgaccca
     4021 gaggcagggg tcaaaactga acctcaagga agggctacag agaggaatct cactgtccca
     4081 tcagaacttg gcagctcagg ctgcagcgac cacagagaag gaacttcatc agctgaagag
     4141 ggccagttac gccagtacag atcagccatc ctggatggaa ctcgccagaa agaaatctca
     4201 agcctggagc gacatgcccc aaatcataaa atagattggc aggctgctgg ggaaggaggt
     4261 ccactggacc gacgagccac ttagttttaa actgccaata aatcttggca agcagactgt
     4321 gaaacttacg attgattttt gtcaacggct tctgatgtgc tccgagaaga gagaggaacc
     4381 agggggaacg gagaagacca gcagacagcc tcagtgccgg gccagagggg ctgtggcaag
     4441 aatgttgcga agtttagggg cgccattcct gtgctgagat gtcagcgtga gcctacgagt
     4501 cccaggtctg cgctgcctct tgccatcagc cagtgcctct ggccaccgtc ttgccgtggg
     4561 ccatcgtggt ctttcttgtt tactaatagg catgattgtt tgtggtaaag cagggattcc
     4621 ctttacaaga gcagctaccc acttaacaat ccagtttcct gaagaaaccc acccaccccg
     4681 agaaggagag gaagggacgt ggcagggttt gtcaattcat agactgtttc caaaaagaat
     4741 ttttaaactt ttccactagg catctgtgtc ctgtgcaaaa tgcattgcct gtttaataaa
     4801 aagtttcaaa catg
//
