LOCUS       NM_013496                819 bp    mRNA    linear   ROD 17-SEP-2024
DEFINITION  Mus musculus cellular retinoic acid binding protein I (Crabp1),
            transcript variant 1, mRNA.
ACCESSION   NM_013496
VERSION     NM_013496.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 819)
  AUTHORS   Nhieu,J., Wei,C.W., Ludwig,M., Drake,J.M. and Wei,L.N.
  TITLE     CRABP1-complexes in exosome secretion
  JOURNAL   Cell Commun Signal 22 (1), 381 (2024)
   PUBMED   39075476
  REMARK    GeneRIF: CRABP1-complexes in exosome secretion.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 819)
  AUTHORS   Carabana,C., Sun,W., Veludo Ramos,C., Huyghe,M., Perkins,M.,
            Maillot,A., Journot,R., Hartani,F., Faraldo,M.M., Lloyd-Lewis,B.
            and Fre,S.
  TITLE     Spatially distinct epithelial and mesenchymal cell subsets along
            progressive lineage restriction in the branching embryonic mammary
            gland
  JOURNAL   EMBO J 43 (12), 2308-2336 (2024)
   PUBMED   38760574
REFERENCE   3  (bases 1 to 819)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 819)
  AUTHORS   Lavoie,O., Turmel,A., Mattoon,P., Desrosiers,W.J., Plamondon,J.,
            Michael,N.J. and Caron,A.
  TITLE     Hypothalamic GABAergic Neurons Expressing Cellular Retinoic Acid
            Binding Protein 1 (CRABP1) Are Sensitive to Metabolic Status and
            Liraglutide in Male Mice
  JOURNAL   Neuroendocrinology 114 (7), 681-697 (2024)
   PUBMED   38631315
  REMARK    GeneRIF: Hypothalamic GABAergic Neurons Expressing Cellular
            Retinoic Acid Binding Protein 1 (CRABP1) Are Sensitive to Metabolic
            Status and Liraglutide in Male Mice.
REFERENCE   5  (bases 1 to 819)
  AUTHORS   Queen,R., Crosier,M., Eley,L., Kerwin,J., Turner,J.E., Yu,J.,
            Alqahtani,A., Dhanaseelan,T., Overman,L., Soetjoadi,H., Baldock,R.,
            Coxhead,J., Boczonadi,V., Laude,A., Cockell,S.J., Kane,M.A.,
            Lisgo,S. and Henderson,D.J.
  TITLE     Spatial transcriptomics reveals novel genes during the remodelling
            of the embryonic human arterial valves
  JOURNAL   PLoS Genet 19 (11), e1010777 (2023)
   PUBMED   38011284
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 819)
  AUTHORS   Smith,D.E., Franco del Amo,F. and Gridley,T.
  TITLE     Isolation of Sna, a mouse gene homologous to the Drosophila genes
            snail and escargot: its expression pattern suggests multiple roles
            during postimplantation development
  JOURNAL   Development 116 (4), 1033-1039 (1992)
   PUBMED   1295727
  REMARK    Erratum:[Development 1993 Mar;117(3):precedi]
REFERENCE   7  (bases 1 to 819)
  AUTHORS   Ruberte,E., Friederich,V., Morriss-Kay,G. and Chambon,P.
  TITLE     Differential distribution patterns of CRABP I and CRABP II
            transcripts during mouse embryogenesis
  JOURNAL   Development 115 (4), 973-987 (1992)
   PUBMED   1333403
REFERENCE   8  (bases 1 to 819)
  AUTHORS   Zhang,J., Liu,Z.P., Jones,T.A., Gierasch,L.M. and Sambrook,J.F.
  TITLE     Mutating the charged residues in the binding pocket of cellular
            retinoic acid-binding protein simultaneously reduces its binding
            affinity to retinoic acid and increases its thermostability
  JOURNAL   Proteins 13 (2), 87-99 (1992)
   PUBMED   1377826
REFERENCE   9  (bases 1 to 819)
  AUTHORS   Maden,M., Horton,C., Graham,A., Leonard,L., Pizzey,J.,
            Siegenthaler,G., Lumsden,A. and Eriksson,U.
  TITLE     Domains of cellular retinoic acid-binding protein I (CRABP I)
            expression in the hindbrain and neural crest of the mouse embryo
  JOURNAL   Mech Dev 37 (1-2), 13-23 (1992)
   PUBMED   1351399
REFERENCE   10 (bases 1 to 819)
  AUTHORS   Geurts van Kessel,A., de Leeuw,H., Dekker,E.J., Rijks,L., Spurr,N.,
            Ledbetter,D., Kootwijk,E. and Vaessen,M.J.
  TITLE     Localization of the cellular retinoic acid binding protein (CRABP)
            gene relative to the acute promyelocytic leukemia-associated
            breakpoint on human chromosome 15
  JOURNAL   Hum Genet 87 (2), 201-204 (1991)
   PUBMED   1648546
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159892.2, AK144397.1 and CD742428.1.
            
            On Oct 18, 2013 this sequence version replaced NM_013496.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB205052.1, AI326249.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                AC159892.2         71549-71597
            50-750              AK144397.1         2-702
            751-751             AC159892.2         79860-79860
            752-801             AK144397.1         704-753
            802-819             CD742428.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..819
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 29.76 cM"
     gene            1..819
                     /gene="Crabp1"
                     /gene_synonym="Crabp-1; CRABP-I; CrabpI; Rbp-5"
                     /note="cellular retinoic acid binding protein I"
                     /db_xref="GeneID:12903"
                     /db_xref="MGI:MGI:88490"
     exon            1..224
                     /gene="Crabp1"
                     /gene_synonym="Crabp-1; CRABP-I; CrabpI; Rbp-5"
                     /inference="alignment:Splign:2.1.0"
     CDS             155..568
                     /gene="Crabp1"
                     /gene_synonym="Crabp-1; CRABP-I; CrabpI; Rbp-5"
                     /note="isoform 1 is encoded by transcript variant 1;
                     cellular retinoic acid-binding protein 1"
                     /codon_start=1
                     /product="cellular retinoic acid-binding protein 1 isoform
                     1"
                     /protein_id="NP_038524.1"
                     /db_xref="CCDS:CCDS23195.1"
                     /db_xref="GeneID:12903"
                     /db_xref="MGI:MGI:88490"
                     /translation="MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEI
                     RQDGDQFYIKTSTTVRTTEINFKVGEGFEEETVDGRKCRSLPTWENENKIHCTQTLLE
                     GDGPKTYWTRELANDELILTFGADDVVCTRIYVRE"
     exon            225..403
                     /gene="Crabp1"
                     /gene_synonym="Crabp-1; CRABP-I; CrabpI; Rbp-5"
                     /inference="alignment:Splign:2.1.0"
     exon            404..517
                     /gene="Crabp1"
                     /gene_synonym="Crabp-1; CRABP-I; CrabpI; Rbp-5"
                     /inference="alignment:Splign:2.1.0"
     exon            518..802
                     /gene="Crabp1"
                     /gene_synonym="Crabp-1; CRABP-I; CrabpI; Rbp-5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      784..789
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Crabp1"
                     /gene_synonym="Crabp-1; CRABP-I; CrabpI; Rbp-5"
                     /note="hexamer: ATTAAA"
     polyA_site      802
                     /gene="Crabp1"
                     /gene_synonym="Crabp-1; CRABP-I; CrabpI; Rbp-5"
                     /note="major polyA site"
ORIGIN      
        1 agaagggggg gggcgctacc ctagcgactc aaggcgcttg cggctgggcg cagaacgcca
       61 gtctctctgc aacgcagcgt gcgaccgctc cgcagcagag gtgggtgcct gcccctgcct
      121 tcgcgccgcc gctacagcca acaccactgc caccatgccc aacttcgccg gtacctggaa
      181 gatgcgcagc agcgagaatt tcgacgagct cctcaaggcg ttgggtgtga acgccatgct
      241 gaggaaggtg gccgtggcgg ctgcgtctaa gccgcacgtg gagatccgcc aagacgggga
      301 tcagttctac atcaagacat ccactactgt gcgcaccacg gagatcaact tcaaggtcgg
      361 agagggcttc gaggaggaga cagtggacgg acgcaaatgc aggagtttac ccacgtggga
      421 gaatgagaac aagattcact gcacacagac acttcttgag ggggatggcc ctaaaactta
      481 ctggacccga gagctggcca acgatgagct aatcctgaca tttggcgccg atgatgtggt
      541 gtgcacaaga atttatgtcc gggagtaaag gtggccagct tgttcctgct tcatgaccgg
      601 atgcgagttc ccctgaggag tatgccgtgg ccccacactg ccagtgggtc tttactccac
      661 acacctctcc cccatgaata ttaggcaacc ccattttccc catgacattg ttgtagtgtc
      721 ctcccctcag gctcttgttg ccttgtgtac ccttggtttg gcatttgcat gattgtacca
      781 gtcattaaac tggttggctg caaaaaaaaa aaaaaaaaa
//
