LOCUS       NM_001368765            7334 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus complement receptor 2 (Cr2), transcript variant 1,
            mRNA.
ACCESSION   NM_001368765 XM_006497221
VERSION     NM_001368765.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7334)
  AUTHORS   Stark,K., Kilani,B., Stockhausen,S., Busse,J., Schubert,I.,
            Tran,T.D., Gaertner,F., Leunig,A., Pekayvaz,K., Nicolai,L.,
            Fumagalli,V., Stermann,J., Stephan,F., David,C., Muller,M.B.,
            Heyman,B., Lux,A., da Palma Guerreiro,A., Frenzel,L.P.,
            Schmidt,C.Q., Dopler,A., Moser,M., Chandraratne,S., von Bruhl,M.L.,
            Lorenz,M., Korff,T., Rudelius,M., Popp,O., Kirchner,M., Mertins,P.,
            Nimmerjahn,F., Iannacone,M., Sperandio,M., Engelmann,B.,
            Verschoor,A. and Massberg,S.
  TITLE     Antibodies and complement are key drivers of thrombosis
  JOURNAL   Immunity 57 (9), 2140-2156 (2024)
   PUBMED   39226900
REFERENCE   2  (bases 1 to 7334)
  AUTHORS   Cumpelik,A., Cody,E., Yu,S.M., Grasset,E.K., Dominguez-Sola,D.,
            Cerutti,A. and Heeger,P.S.
  TITLE     Cutting Edge: Neutrophil Complement Receptor Signaling Is Required
            for BAFF-Dependent Humoral Responses in Mice
  JOURNAL   J Immunol 210 (1), 19-23 (2023)
   PUBMED   36454023
REFERENCE   3  (bases 1 to 7334)
  AUTHORS   Lenti,E., Genovese,L., Bianchessi,S., Maurizio,A., Sain,S.B., di
            Lillo,A., Mattavelli,G., Harel,I., Bernassola,F., Hehlgans,T.,
            Pfeffer,K., Crosti,M., Abrignani,S., Evans,S.M., Sitia,G.,
            Guimaraes-Camboa,N., Russo,V., van de Pavert,S.A.,
            Garcia-Manteiga,J.M. and Brendolan,A.
  TITLE     Fate mapping and scRNA sequencing reveal origin and diversity of
            lymph node stromal precursors
  JOURNAL   Immunity 55 (4), 606-622 (2022)
   PUBMED   35358427
REFERENCE   4  (bases 1 to 7334)
  AUTHORS   Schriek,P., Ching,A.C., Moily,N.S., Moffat,J., Beattie,L.,
            Steiner,T.M., Hosking,L.M., Thurman,J.M., Holers,V.M., Ishido,S.,
            Lahoud,M.H., Caminschi,I., Heath,W.R., Mintern,J.D. and
            Villadangos,J.A.
  TITLE     Marginal zone B cells acquire dendritic cell functions by
            trogocytosis
  JOURNAL   Science 375 (6581), eabf7470 (2022)
   PUBMED   35143312
REFERENCE   5  (bases 1 to 7334)
  AUTHORS   Read,B.J., Won,L., Kraft,J.C., Sappington,I., Aung,A., Wu,S.,
            Bals,J., Chen,C., Lee,K.K., Lingwood,D., King,N.P. and Irvine,D.J.
  TITLE     Mannose-binding lectin and complement mediate follicular
            localization and enhanced immunogenicity of diverse protein
            nanoparticle immunogens
  JOURNAL   Cell Rep 38 (2), 110217 (2022)
   PUBMED   35021101
REFERENCE   6  (bases 1 to 7334)
  AUTHORS   Morse,H.C. 3rd.
  TITLE     Genetic nomenclature for loci controlling surface antigens of mouse
            hemopoietic cells
  JOURNAL   J Immunol 149 (10), 3129-3134 (1992)
   PUBMED   1431091
  REMARK    Review article
            Erratum:[J Immunol 1993 Mar 15;150(6):2563]
REFERENCE   7  (bases 1 to 7334)
  AUTHORS   Hameister,H., Schulz,W.A., Meyer,J., Thoma,S., Adolph,S., Gaa,A.
            and von Deimling,O.
  TITLE     Gene order and genetic distance of 13 loci spanning murine
            chromosome 15
  JOURNAL   Genomics 14 (2), 417-422 (1992)
   PUBMED   1358803
REFERENCE   8  (bases 1 to 7334)
  AUTHORS   Christensen,S.M., Martin,B.K., Tan,S.S. and Weis,J.H.
  TITLE     Identification of sites for distinct DNA binding proteins including
            Oct-1 and Oct-2 in the Cr2 gene
  JOURNAL   J Immunol 148 (11), 3610-3617 (1992)
   PUBMED   1534100
REFERENCE   9  (bases 1 to 7334)
  AUTHORS   Taketo,M., Howard,T.A. and Seldin,M.F.
  TITLE     Mapping of recombinant retrovirus integration sites that cause
            expression of the viral genome in murine embryonal carcinoma cells
  JOURNAL   Mamm Genome 2 (4), 240-245 (1992)
   PUBMED   1543915
REFERENCE   10 (bases 1 to 7334)
  AUTHORS   Fingeroth,J.D.
  TITLE     Comparative structure and evolution of murine CR2. The homolog of
            the human C3d/EBV receptor (CD21)
  JOURNAL   J Immunol 144 (9), 3458-3467 (1990)
   PUBMED   2139457
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109145.11 and AC139206.5.
            
            On Feb 25, 2019 this sequence version replaced XM_006497221.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849375, SAMN00849377
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               AC109145.11        144077-144243
            168-347             AC109145.11        149626-149805
            348-447             AC109145.11        150995-151094
            448-533             AC109145.11        151452-151537
            534-932             AC109145.11        152064-152462
            933-1106            AC109145.11        154406-154579
            1107-1209           AC139206.5         277851-277953       c
            1210-1295           AC139206.5         277141-277226       c
            1296-1685           AC139206.5         275300-275689       c
            1686-1874           AC139206.5         272881-273069       c
            1875-1974           AC139206.5         272698-272797       c
            1975-2057           AC139206.5         272372-272454       c
            2058-2465           AC139206.5         271518-271925       c
            2466-2642           AC139206.5         270680-270856       c
            2643-2733           AC139206.5         270514-270604       c
            2734-2810           AC139206.5         270162-270238       c
            2811-3218           AC139206.5         269239-269646       c
            3219-3297           AC139206.5         268382-268460       c
            3298-3380           AC139206.5         267986-268068       c
            3381-3773           AC139206.5         267227-267619       c
            3774-3959           AC139206.5         266234-266419       c
            3960-4145           AC139206.5         263674-263859       c
            4146-4169           AC139206.5         263025-263048       c
            4170-4242           AC139206.5         262074-262146       c
            4243-4347           AC139206.5         253281-253385       c
            4348-7334           AC139206.5         248914-251900       c
FEATURES             Location/Qualifiers
     source          1..7334
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 98.44 cM"
     gene            1..7334
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /note="complement receptor 2"
                     /db_xref="GeneID:12902"
                     /db_xref="MGI:MGI:88489"
     exon            1..167
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            168..347
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            348..447
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            448..533
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            534..932
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1106
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1209
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1295
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1685
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1874
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..1974
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1975..2057
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2465
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2466..2642
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2643..2733
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2734..2810
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2811..3218
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3219..3297
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3298..3380
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3381..3773
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3774..3959
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3960..4145
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4146..4169
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4170..4242
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4243..4347
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4348..7334
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4460..4465
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /note="hexamer: ATTAAA"
     polyA_site      4480
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /note="major polyA site"
     regulatory      6756..6761
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
                     /note="hexamer: AATAAA"
     polyA_site      6783
                     /gene="Cr2"
                     /gene_synonym="C3DR; CD21; CD35; Cr-1; Cr-2; Cr1"
ORIGIN      
        1 agccagccgc aggcagccag ccccgcaggc agccagcccc gtcctcttcc tctccttgct
       61 acaggctcac aactcacaga gcgcaacctg ccattggact gctgcacaca tgggatcctt
      121 gggttcgctc tgggttttct tcactctcat cactccagga gttcttggtc agtgtaagtt
      181 gctgccaaag tattcttttg ctaaaccttc tattgtgagt gataaatctg agtttgccat
      241 tggaacaact tgggaataca aatgtcgccc tgggtatttt aggaagtcat ttattatcac
      301 ctgcttagaa acctccaagt ggtcagatgc tcagcagttc tgtaaacgta aaccatgtat
      361 gaatcctcaa gaacccctcc atggttctgt gcatataaac acgggtatcg agtttgggtc
      421 aacaattacg tattcttgta atcaaggata tcgactcatt ggtgactcgt ctgctacatg
      481 tattgtatca gacaatactg taatgtggga taatgatatg cctctttgtg aatctattcc
      541 ttgtgagtca cctccagcca tctccaatgg agacttctac agcagcagca gagacagctt
      601 tttctatggg atggtagtaa cttattattg ccataccgga aagaataggg aaaaactgtt
      661 tgatctggtg ggtgagaagt caatatattg taccagcaaa gacaatcaag ttggcatctg
      721 gaatagtcca cctcctcagt gtattcctag agtcaagtgc ccaatgccag aaattgaaaa
      781 tggactagtg gagtctggat ttaaacactc cttcttctta aatgatacag taatatttaa
      841 gtgcaaatct ggctttacca tgaaaggcag cagaatagca tggtgccagc caaacagcaa
      901 atggagccct ccattgccaa catgcttcat gggatgtcta ccacctcaaa atatcctcca
      961 tggtgattat aacaaaaagg atgagttctt ctctgttggc cagaaagtgt catatagctg
     1021 taaccctggc tatactctca ttggaactaa cctcgtggag tgtacatcct tgggaacctg
     1081 gagcaataca gtcccgacat gtgaagtgaa atcatgtgat gcaattccaa accatcttct
     1141 ccatggccgt gtgtttcttc cccctaatct ccagcttggg gcagaggttt cctttgtttg
     1201 tgacttaggg ttccagttaa aaggcaaacc ttctagtcag tgtatcccag aaggagagac
     1261 agtaatctgg aataataagt ttcctgtctg tgaacagatt tcttgtgacc ctcctcctga
     1321 agtcaaaaat gctcggaaac cctattattc tcttcccata gttcctggaa ctgttctgag
     1381 gtacacttgt tcacctagct accgcctcat tggagaaaag gctatctttt gtataagtga
     1441 aaatcaagtg catgccacct gggataaagc tcctcctata tgtgaatctg tgaataaaac
     1501 catttcttgc tcagatccca tagtaccagg gggattcatg aataaaggat ctaaggcacc
     1561 attcagacat ggtgattctg tgacatttac ctgtaaagcc aacttcacca tgaaaggaag
     1621 caaaactgtc tggtgccagg caaatgaaat gtggggacca acagctctgc cagtctgtga
     1681 gagtgatttc cctctggagt gcccatcact tccaacgatt cataatggac accacacagg
     1741 acagcatgtt gaccagtttg ttgcggggtt gtctgtgaca tacagttgtg aacctggcta
     1801 tttgctcact ggaaaaaaga caattaagtg cttatcttca ggagactggg atggtgtcat
     1861 cccgacatgc aaagaggccc agtgtgaaca tccaggaaag tttcccaatg ggcaggtaaa
     1921 ggaacctctg agccttcagg ttggcacaac tgtgtacttc tcctgtaatg aagggtacca
     1981 attacaagga caaccctcta gtcagtgtgt aattgttgaa cagaaagcca tctggactaa
     2041 gaagccagta tgtaaagaaa ttctctgccc accacctcca cctgttcgta atggaagtca
     2101 tacaggcagc ttttcagaaa atgtaccata tggaagcaca gttacctaca cctgtgaccc
     2161 aagcccagag aaaggcgtga gcttcactct tattggagag aagactatca attgtactac
     2221 tggtagtcag aagactggga tctggagtgg ccctgctcca tattgtgtac tttcaacttc
     2281 tgcagttctg tgtttacaac cgaagatcaa aagagggcaa atattatcta ttttgaaaga
     2341 tagttattca tataatgaca ctgtggcatt ttcttgtgaa cctggcttca ccttgaaggg
     2401 caacaggagc attcgatgca atgctcatgg cacatgggag ccaccggtac cagtgtgtga
     2461 aaaaggatgt caggctcctc ctaaaattat caatgggcaa aaagaagata gttacttgct
     2521 caactttgac cctggtacat ccataagata tagctgtgac cctggctatt tactggtggg
     2581 agaggacact atacattgca cccctgaggg gaagtggaca cccattactc cccagtgcac
     2641 agttgcagag tgtaagccag taggaccaca tctctttaag aggcctcaga atcagtttat
     2701 taggacagct gttaattctt cttgtgatga agggttccag ttaagtgaga gtgcttatca
     2761 actgtgtcaa ggtacaattc cttggtttat agaaatccgt ctttgtaaag aaatcacctg
     2821 cccaccacct cctgttatac acaacgggac acatacatgg agttcctcag aagatgtccc
     2881 atatggaact gtggtcacat acatgtgcta tcctgggcca gaggaaggcg taaaattcaa
     2941 actcatcggg gagcaaacca tccactgtac aagtgacagc agaggaagag gctcctggag
     3001 tagccctgct cctctctgta aactttccct cccagctgtc cagtgcacag acgttcatgt
     3061 tgaaaatgga gtcaagctca ctgacaataa agccccatat ttctacaatg atagtgtgat
     3121 gttcaagtgt gatgatggat atattttgag tggaagcagt cagatccggt gtaaagccaa
     3181 taatacctgg gatcctgaaa aaccactttg taaaaaagaa ggatgtgagc ctatgagagt
     3241 acatggcctt ccagatgatt cacatataaa actagtgaaa agaacctgtc aaaatgggta
     3301 ccagttgact ggatatactt atgagaagtg tcaaaatgct gagaatggga cttggtttaa
     3361 aaagattgaa gtttgtacag ttattctctg tcaacctcca ccaaaaattg caaatggtgg
     3421 tcacacaggc atgatggcaa agcacttcct atatggaaat gaagtttctt atgaatgtga
     3481 tgaagggttc tatcttttgg gagagaaaag tttgcagtgc gtaaatgatt ctaaaggtca
     3541 tggctcttgg agtggacctc caccacaatg cttacaatct tctcctctaa ctcattgccc
     3601 cgatccagaa gtcaaacatg gttacaaact caataaaact cattctgcat tttctcataa
     3661 tgacatagta cattttgtct gcaatcaagg cttcatcatg aacggcagcc acttgataag
     3721 gtgtcatact aataacacat ggttaccagg tgtaccaact tgtatcagaa aggcttcttt
     3781 agggtgtcag tctccatcca caatccccaa tgggaatcat actggtggga gtatagctcg
     3841 atttccccct ggaatgtcag tcatgtacag ttgctaccaa ggcttcctta tggctggaga
     3901 ggcacgtctt atctgtactc atgagggtac ctggagtcaa cctccccctt tttgcaaaga
     3961 ggtaaactgt agcttccctg aagatacaaa tggaatccag aagggatttc aacctgggaa
     4021 aacctatcga tttggggcta ctgtgactct ggaatgtgag gatgggtata ccttggaggg
     4081 aagtccccag agccagtgcc aggatgacag ccaatggaac cctcccttgg ctctttgcaa
     4141 ataccggtca actattcctc ttatttgtgg tatttctgtg ggctcagcac ttatcatttt
     4201 gatgagtgtc ggcttctgta tgatattaaa acacagagaa agcaattatt atacaaagac
     4261 aagacccaaa gaaggagctc ttcatttaga aacacgagaa gtatattcta ttgatccata
     4321 taacccagca agctgatgac atgacaaatc aagatgtaga actctcagct acctcttcag
     4381 caccatatct gcttacatgc caccaagcta ccctccacga caataatgga ctaaacctct
     4441 gatttgtaag ccagccccaa ttaaatgttt ttctctataa gagttgtcaa agttatggtg
     4501 tctcttcaca gcaatagaaa cccaaaataa gacagaagtt gaaactaggg actggggtat
     4561 tgttgtgata gacctgacca tgcttttgtt tggagacatg tggactttgg gtttggaaag
     4621 cagtggaatg ctttaagcac agtttaatag accaccctag aaggagcaca gaagacaatg
     4681 atgtttaggg tgatttgaac tatgagggcc tggttcaaga ggtttcagat aagaagaact
     4741 ttagtatgtg gcctacagat tgttcttgtg atatttcaga gaaggtagtg gctgctctct
     4801 gctcttgtca aaaaaaaaaa aaaaaaaatt gcccatggct aaatggaaga gtttggataa
     4861 attttatgtt ggcaaaggag atctcagaac agtctagatt gactctgttg tgcagttact
     4921 agtggtcact tttatgcaga cctataacta ataggagcaa gctgagcaag gaaaaataca
     4981 aaatgtaaca tttgaggaga aaaggaacac ggaaagtgtc aacagtttaa aggaaagcaa
     5041 gaccctacct aactaagctt cctgtttgta aaaaagaatt aaagaaaagt gaaagggaat
     5101 taaagaaacg tttagggcaa agcatggtag tgtacacttt taatcccaga gtttaaggtt
     5161 agcctggtct gcaaagcaag ttgcaggaca gccatgctta tgcaatgaag aaagtttcta
     5221 aaacagaaag atagtgaaaa attatttgaa tgagggcccc agccaacaac atatcatggt
     5281 ggctttggct atgtggttct ggctgtaaag tcaaggatac aagaaagggg tcatggactc
     5341 ttctgttgtg gctaggaaaa gctaaagagg ccagacatgt gtcaggagtg tccctgcatg
     5401 gagacctaga gaggtcattg tgtgaagcta tgaaggtgaa gcctggattg ccttgaagac
     5461 cccaaaatgt tggagatacc agagctgtgg gataccttca aaggagagct gctaacagag
     5521 aatggaatca gtccatgaga aagaggcata ttgcagtcaa caaagatgaa aggagttgga
     5581 ggtctgaaga atattttaac ttcagacatg gagatacaga gtttgcccag atagtttttg
     5641 attcagaatt tcttcgatgc tcccctttat atttataatg tatatcctat gacattatat
     5701 tgaggcccac agagaagaac aacaaacaga actcatggga tgtggcacaa tcatgatggg
     5761 tgtgcctcag agaggcagag ctccaaggac tagatgtctt gaggacttga tgctgttatg
     5821 gaaatcgctc tatagttctc tcaaacatca tgctgctcct aaactatgag ttgtatgaaa
     5881 actctaaggg gtctcccagc ccctgactgg gcagtatctt tgacacttag caataatagt
     5941 gattgatctt tttcaagctt tgctgctggt gcagatgaat gattcattta taaacctcag
     6001 taagacttag agttatacat gtctagtaac attcaccacc cttagaaaga atttggagat
     6061 atggattgtt aggaaagtta ggttaagatg tttttgctag tatatttgat atagaaaatt
     6121 ttagagaaca atctgaagtc cagaaaggaa cattcttaat agttgggcta ggaaaatttt
     6181 gaggtcaggg gataagaaca atggaagccc aacattggct gacatgcctc tcttgctaaa
     6241 gctgggctaa tgatcaaggt gatgattaat ttcatgtact catttttgcc ctcagcttcc
     6301 tggtattgat taaataaaaa attgttaatg agtagatgtg caccctaagg atttaaagta
     6361 gaagtgactg attttttcta taaaaattta gatttgtgat tcctttaaga tttttataag
     6421 attacttttt aagataaaat tattctttct ttgcaactgc aaatttctgc ctgccagtaa
     6481 aagaaactgg ctgagaaaat tagcctgctt gcttatactt tgttaatata taacaagtgc
     6541 ttgcttacaa atgcatgtgg gtttttgaaa atatttttta atacatgata cataaagcat
     6601 ttgatcatga gatgatatag ggggacactt tttttctttt ctttttctat gtatactcac
     6661 tgtaattttt cacttaaaga aaaatggaat gttgtcacat tgtaattttt atcctgcttg
     6721 agagattttg gtgagtcaca taagctatgg gggaaaataa agttaagaga acttgtataa
     6781 taattaagaa gattctgtat ctgtgtgttc tgctgactcc atgcccccta cttcagactc
     6841 tgatgtgtca aagctggata tccttatatg ttggaagtat gtgatctgct ttttgatttt
     6901 gattttacag gaattaaagt taaaagaatg gatgagtctc agaagaagct ttgaactttg
     6961 gactttcaaa caagtttgag attgttatag actatgggga cttctgagat tggagtcaat
     7021 gcattttgca ttatgatatg gctaaatcct attgggtcca ggaagtagaa tgtggtagtt
     7081 tgaacaaaat ggcccctata ggcctattgg gagttggact attaggaagc ttgcccttgt
     7141 tggagtaaat atggccttgt tgaaggaagt gtgtttcatt tacttttttg ctgcctgagg
     7201 atcaatatgt agaactctca gctacctctc tagcactatg tctgactgca tgctgccaac
     7261 tttcttccca tgacaataat ggactagaac tctgaactgt aagcctgcca caattaaaag
     7321 tttttcttta taag
//
