LOCUS       NM_026682               1234 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus cleavage and polyadenylation specific factor 4-like
            (Cpsf4l), transcript variant 1, mRNA.
ACCESSION   NM_026682
VERSION     NM_026682.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1234)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1234)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK161074.1, DV659633.1 and DV657463.1.
            
            On Sep 1, 2009 this sequence version replaced NM_026682.1.
            
            Transcript Variant: This variant (1) encodes isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC016190.1, DV659633.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AK161074.1         2-11
            11-743              DV659633.1         1-733
            744-1234            DV657463.1         142-632
FEATURES             Location/Qualifiers
     source          1..1234
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 79.17 cM"
     gene            1..1234
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /note="cleavage and polyadenylation specific factor
                     4-like"
                     /db_xref="GeneID:52670"
                     /db_xref="MGI:MGI:1277182"
     exon            1..140
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..724
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="putative cleavage and polyadenylation
                     specificity factor subunit 4-like protein isoform 1"
                     /protein_id="NP_080958.2"
                     /db_xref="CCDS:CCDS25603.2"
                     /db_xref="GeneID:52670"
                     /db_xref="MGI:MGI:1277182"
                     /translation="MEEVIAGLQGFTFAFELDVESQKGTGLLPFQGMDKSSSAVCNFF
                     AKGLCVKGMLCPLRHEQGEKLVVCKHWLRGLCRKSDCCDFLHQYDVSKMPVCYFHSKF
                     GNCSNKECLFLHLKPVLKLQDCPWYNQGFCKEVGPLCKYRHVHQVLCPNYFTGFCPEG
                     PQCQFGHPKMSPPFHPSNVKLQPVNQPWDSTTSTGNTLVSPFQAKPMVHGQRRWSLPQ
                     ACSSRAHPAP"
     exon            141..191
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /inference="alignment:Splign:2.1.0"
     exon            192..344
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /inference="alignment:Splign:2.1.0"
     exon            345..440
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /inference="alignment:Splign:2.1.0"
     exon            441..537
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /inference="alignment:Splign:2.1.0"
     exon            538..577
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /inference="alignment:Splign:2.1.0"
     exon            578..724
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /inference="alignment:Splign:2.1.0"
     exon            725..1220
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1199..1204
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /note="hexamer: AATATA"
     polyA_site      1220
                     /gene="Cpsf4l"
                     /gene_synonym="0610010C04Rik; 1500000C01Rik; D11Ertd636e"
                     /note="major polyA site"
ORIGIN      
        1 tcttggctct ttctgctttt ccggcgggag acggaagatg gaggaggtca ttgccgggct
       61 gcaagggttc acgttcgcct ttgagctgga tgtggaatcg cagaagggca ctgggctact
      121 gcctttccag ggcatggaca agtccagttc agctgtgtgc aacttcttcg ctaaagggct
      181 ctgtgtgaaa gggatgctat gcccactccg gcacgagcag ggtgagaagc tggtggtgtg
      241 caaacactgg cttcgaggcc tctgccggaa gagtgattgc tgcgacttcc tgcaccagta
      301 tgacgtcagc aagatgcccg tgtgctattt ccactccaag ttcgggaact gcagcaacaa
      361 ggaatgcctg ttcctgcact tgaagccagt tctcaagctc caggactgcc cgtggtataa
      421 ccaagggttc tgcaaggaag taggtcccct gtgtaaatac cgccatgttc atcaagtact
      481 gtgtcccaac tacttcaccg gcttctgccc cgagggacct cagtgccaat ttgggcaccc
      541 taagatgagt cctccgttcc atcccagtaa tgtgaagctg cagcctgtca accagccatg
      601 ggattcaaca acttctactg gcaacactct ggtgtcccct ttccaggcaa agcccatggt
      661 ccacggtcag aggaggtgga gtctgcctca ggcctgcagc tcaagggcac accctgcacc
      721 ttaggccacc atgccagcaa agtaagctgt acccgttgga gccatcaaaa cctagtctga
      781 agcgagggag ttggacgttc tcctaggtaa gggctggctc catggcctcc tcagggtatt
      841 ctgtacccag tggtccagtg agctccatca cggtaatgag atgcaggatg cagaaagagc
      901 ctcctctacc tggcttattt ccatttatcc tgcacatgcc cgagatgcca atcatacagc
      961 aggatacgag gtcagctgac tgtggaaggg aggagtcatt catgagccag gagaacaaag
     1021 tgcacttgaa gctgtgaact ctacagagtc agtcagtcaa catcccatgc ttggctccca
     1081 cgctcccgca gactgctatg ggtcaacggc ctcaagtgct cccaaaaacg ggcaatccga
     1141 tccaacgatt gcttttactt tgacagctgt ttgcctgtac agcttattta tactcgagaa
     1201 tatactgtgt gttctgtgta aaaaaaaaaa aaaa
//
