LOCUS       NM_001291248            1725 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus cleavage and polyadenylation specific factor 4
            (Cpsf4), transcript variant 1, mRNA.
ACCESSION   NM_001291248 XM_006504846
VERSION     NM_001291248.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1725)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1725)
  AUTHORS   Oeschger,F.M., Wang,W.Z., Lee,S., Garcia-Moreno,F., Goffinet,A.M.,
            Arbones,M.L., Rakic,S. and Molnar,Z.
  TITLE     Gene expression analysis of the embryonic subplate
  JOURNAL   Cereb Cortex 22 (6), 1343-1359 (2012)
   PUBMED   21862448
REFERENCE   3  (bases 1 to 1725)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   4  (bases 1 to 1725)
  AUTHORS   Bai,C. and Tolias,P.P.
  TITLE     Drosophila clipper/CPSF 30K is a post-transcriptionally regulated
            nuclear protein that binds RNA containing GC clusters
  JOURNAL   Nucleic Acids Res 26 (7), 1597-1604 (1998)
   PUBMED   9512528
REFERENCE   5  (bases 1 to 1725)
  AUTHORS   Bai,C. and Tolias,P.P.
  TITLE     Cleavage of RNA hairpins mediated by a developmentally regulated
            CCCH zinc finger protein
  JOURNAL   Mol Cell Biol 16 (12), 6661-6667 (1996)
   PUBMED   8943320
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127411.3, AK046064.1, AF033201.1 and AI324081.1.
            
            On Mar 29, 2014 this sequence version replaced XM_006504846.1.
            
            Transcript Variant: This variant (1) encodes isoform a.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.63341.1,
                                           SRR5189679.127870.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                AC127411.3         190580-190590       c
            12-192              AK046064.1         2-182
            193-757             AF033201.1         10-574
            758-1715            AK046064.1         649-1606
            1716-1725           AI324081.1         1-10                c
FEATURES             Location/Qualifiers
     source          1..1725
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 85.08 cM"
     gene            1..1725
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /note="cleavage and polyadenylation specific factor 4"
                     /db_xref="GeneID:54188"
                     /db_xref="MGI:MGI:1861602"
     exon            1..247
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..879
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /note="isoform a is encoded by transcript variant 1;
                     musculus clipper/cleavage and polyadenylation specificity
                     factor 30 kDa subunit; cleavage and polyadenylation
                     specificity factor subunit 4; clipper homolog;
                     clipper/CPSF 30K; CPSF 30 kDa subunit; cleavage and
                     polyadenylation specific factor 4, 30kD subunit"
                     /codon_start=1
                     /product="cleavage and polyadenylation specificity factor
                     subunit 4 isoform a"
                     /protein_id="NP_001278177.1"
                     /db_xref="CCDS:CCDS71710.1"
                     /db_xref="GeneID:54188"
                     /db_xref="MGI:MGI:1861602"
                     /translation="MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFF
                     LKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKF
                     GECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGP
                     SCKFMHPRFELPMGTTEQPPLPQQTQPPTKQRAPQVIGVMQSQNSSAGNRGPRPLEQV
                     TCYKCGEKGHYANRCTKGHLAFLSGQ"
     exon            248..298
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            299..451
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            452..547
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            548..641
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            642..714
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            715..810
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            811..1716
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1697..1702
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /note="hexamer: ATTAAA"
     polyA_site      1716
                     /gene="Cpsf4"
                     /gene_synonym="30kDa"
                     /note="major polyA site"
ORIGIN      
        1 gcgctcccgg catccctcgc ggggcggcgg ctgcggcggc ggcggtggcg gcaagcgaga
       61 aggggacggg gagaggtagc gtgagttgcg gagagcggct gagagacctg agggggagct
      121 gggcccgagg ccgccgccgc cgccatgcag gaaataatcg ccagcgtaga tcacatcaag
      181 ttcgacttgg agatcgccgt ggagcagcag ctcggggcgc agccgctgcc cttccccggc
      241 atggataagt cgggggctgc tgtctgtgaa ttctttttga aagccgcctg tggcaaaggg
      301 ggcatgtgtc cattccgcca catcagtggt gagaagacag ttgtgtgcaa acactggctg
      361 agaggactgt gcaagaaagg ggaccagtgt gagttcttgc atgaatatga catgaccaag
      421 atgcctgagt gctactttta ctccaagttc ggggaatgca gcaataagga gtgccccttc
      481 ctgcacatcg accctgaatc caagatcaag gactgccctt ggtatgaccg cggcttctgt
      541 aagcatggtc ccctgtgtag gcatcggcac acccggagag tcatttgtgt gaactacctt
      601 gttggattct gccctgaggg accatcatgt aaattcatgc accctcgatt tgaactgccc
      661 atgggaacca ctgagcaacc cccactaccg cagcagacac agcctccaac aaagcagaga
      721 gccccgcagg tcattggggt catgcagagt caaaacagca gtgcaggcaa ccggggaccc
      781 cggccgctgg agcaagtcac ttgctacaag tgtggtgaga aaggacacta cgccaacaga
      841 tgcaccaaag ggcatttggc ctttctcagt gggcagtgac agcagcagca gcagcagcag
      901 ctggaatcac tgtggagcag cctgaggggc ctgctgaggg gagcacgcac ttggctgctg
      961 actgtaggac tggcaggact cgggctggag ctgcaggcat accagtcagg gctcattttg
     1021 aggggccatg tctgtccttt cattttgcta taattttttt tgtttaaaaa agaaggacca
     1081 tgtgcttcag ttgggtcccc tgagccagag tttgcctgga catcagtgcc tcgttttttt
     1141 atttttttat tttttggact ccctgtacac tgtcctgttg gggagagaga agctgggaag
     1201 ggctatgctt cgtcctgggt ggaagacggc tggcagttcc cctcagggcc tcatttaaac
     1261 accagcacct aaagaggacg ggtggatcat gtggggctgt ggccaggtca gcctgctttc
     1321 tccatgtcct gctgacatct gaaactgtgc ctatgaatgt gatttgaaca caggagcccc
     1381 ttcctcacaa acccggagca cccactgcct ggcctggccc taactgtggg aggggcgcca
     1441 ggctccccag gctgagctgc ttgtctgggc ttgcttgtgg gcaccttcag ccagtgctgc
     1501 agaccaccct gaaatagctg acccagttgg tctgcgccta cctcctgcca agcaagctct
     1561 gtgctgtcac tcagacacct gtggcatgca gaggccgccc atcctcgagc ctagaaaatg
     1621 tgaatccatc acctgcaacc tgctgggcaa gtgggcctat ccaagttcgg ttataagaat
     1681 actttctatg aggttgatta aaaagcttgt tttttaaaaa aaaaa
//
