LOCUS       NM_025628                487 bp    mRNA    linear   ROD 18-NOV-2024
DEFINITION  Mus musculus cytochrome c oxidase, subunit 6B1 (Cox6b1), transcript
            variant 1, mRNA.
ACCESSION   NM_025628 XM_909663
VERSION     NM_025628.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 487)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     Structure and assembly of the mammalian mitochondrial supercomplex
            CIII2CIV
  JOURNAL   Nature 598 (7880), 364-367 (2021)
   PUBMED   34616041
REFERENCE   4  (bases 1 to 487)
  AUTHORS   Yao,Y., Liu,Q., Adrianto,I., Wu,X., Glassbrook,J., Khalasawi,N.,
            Yin,C., Yi,Q., Dong,Z., Geissmann,F., Zhou,L. and Mi,Q.S.
  TITLE     Histone deacetylase 3 controls lung alveolar macrophage development
            and homeostasis
  JOURNAL   Nat Commun 11 (1), 3822 (2020)
   PUBMED   32732898
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 487)
  AUTHORS   Cui,X.S., Li,X.Y., Jeong,Y.J., Jun,J.H. and Kim,N.H.
  TITLE     Gene expression of cox5a, 5b, or 6b1 and their roles in
            preimplantation mouse embryos
  JOURNAL   Biol Reprod 74 (3), 601-610 (2006)
   PUBMED   16291927
  REMARK    GeneRIF: gene expression of the Cox subunits, Cox5a, 5b, and 6b1 is
            not required for embryo developmental events up to the blastocyst
            stage
REFERENCE   6  (bases 1 to 487)
  AUTHORS   Grossman,L.I. and Lomax,M.I.
  TITLE     Nuclear genes for cytochrome c oxidase
  JOURNAL   Biochim Biophys Acta 1352 (2), 174-192 (1997)
   PUBMED   9199249
  REMARK    Review article
REFERENCE   7  (bases 1 to 487)
  AUTHORS   Stubbs,L., Carver,E.A., Shannon,M.E., Kim,J., Geisler,J.,
            Generoso,E.E., Stanford,B.G., Dunn,W.C., Mohrenweiser,H.,
            Zimmermann,W., Watt,S.M. and Ashworth,L.K.
  TITLE     Detailed comparative map of human chromosome 19q and related
            regions of the mouse genome
  JOURNAL   Genomics 35 (3), 499-508 (1996)
   PUBMED   8812484
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK007996.1 and AW047421.1.
            
            On Jun 9, 2018 this sequence version replaced NM_025628.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AV449586.1, BQ747274.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-468               AK007996.1         39-506
            469-487             AW047421.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 18.84 cM"
     gene            1..487
                     /gene="Cox6b1"
                     /gene_synonym="2010000G05Rik; COX VIb-1; Cox6b"
                     /note="cytochrome c oxidase, subunit 6B1"
                     /db_xref="GeneID:110323"
                     /db_xref="MGI:MGI:107460"
     exon            1..64
                     /gene="Cox6b1"
                     /gene_synonym="2010000G05Rik; COX VIb-1; Cox6b"
                     /inference="alignment:Splign:2.1.0"
     exon            65..178
                     /gene="Cox6b1"
                     /gene_synonym="2010000G05Rik; COX VIb-1; Cox6b"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..333
                     /gene="Cox6b1"
                     /gene_synonym="2010000G05Rik; COX VIb-1; Cox6b"
                     /EC_number="7.1.1.9"
                     /note="cytochrome c oxidase, subunit VIb polypeptide 1"
                     /codon_start=1
                     /product="cytochrome c oxidase subunit 6B1"
                     /protein_id="NP_079904.1"
                     /db_xref="CCDS:CCDS39887.1"
                     /db_xref="GeneID:110323"
                     /db_xref="MGI:MGI:107460"
                     /translation="MAEDIKTKIKNYKTAPFDSRFPNQNQTKNCWQNYLDFHRCEKAM
                     TAKGGDVSVCEWYRRVYKSLCPVSWVSAWDDRIAEGTFPGKI"
     exon            179..279
                     /gene="Cox6b1"
                     /gene_synonym="2010000G05Rik; COX VIb-1; Cox6b"
                     /inference="alignment:Splign:2.1.0"
     exon            280..471
                     /gene="Cox6b1"
                     /gene_synonym="2010000G05Rik; COX VIb-1; Cox6b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      446..451
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cox6b1"
                     /gene_synonym="2010000G05Rik; COX VIb-1; Cox6b"
                     /note="hexamer: AATAAA"
     polyA_site      471
                     /gene="Cox6b1"
                     /gene_synonym="2010000G05Rik; COX VIb-1; Cox6b"
                     /note="major polyA site"
ORIGIN      
        1 gtctgacatt ggcgtctttg ctaagggtca cattgaagta acgctactcc gggacaatct
       61 ttaggagtca ggatggctga agacatcaag actaaaatca agaactacaa aactgccccc
      121 tttgacagcc gcttccccaa ccagaaccag actaagaact gttggcagaa ctacctggac
      181 ttccaccgct gtgagaaggc aatgacggcc aaggggggtg atgtctccgt gtgtgagtgg
      241 taccggcgtg tgtacaagtc cctctgtccc gtgtcatggg tctcagcctg ggatgaccgc
      301 atagctgaag gcacatttcc tgggaagatc tgacctggct ccgcccacct ctcctctgtt
      361 ctttgtcttt ctccccggat agaaaagggg gacctcagca tatgatggtc cttaccctgg
      421 gaccctgaat catgatgcaa ctactaataa aaactcactg gaaaagtttc aaaaaaaaaa
      481 aaaaaaa
//
