LOCUS       NP_079904                 86 aa            linear   ROD 18-NOV-2024
DEFINITION  cytochrome c oxidase subunit 6B1 [Mus musculus].
ACCESSION   NP_079904 XP_914756
VERSION     NP_079904.1
DBSOURCE    REFSEQ: accession NM_025628.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 86)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     SCAF1 drives the compositional diversity of mammalian respirasomes
  JOURNAL   Nat Struct Mol Biol 31 (7), 1061-1071 (2024)
   PUBMED   38575788
REFERENCE   2  (residues 1 to 86)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (residues 1 to 86)
  AUTHORS   Vercellino,I. and Sazanov,L.A.
  TITLE     Structure and assembly of the mammalian mitochondrial supercomplex
            CIII2CIV
  JOURNAL   Nature 598 (7880), 364-367 (2021)
   PUBMED   34616041
REFERENCE   4  (residues 1 to 86)
  AUTHORS   Yao,Y., Liu,Q., Adrianto,I., Wu,X., Glassbrook,J., Khalasawi,N.,
            Yin,C., Yi,Q., Dong,Z., Geissmann,F., Zhou,L. and Mi,Q.S.
  TITLE     Histone deacetylase 3 controls lung alveolar macrophage development
            and homeostasis
  JOURNAL   Nat Commun 11 (1), 3822 (2020)
   PUBMED   32732898
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 86)
  AUTHORS   Cui,X.S., Li,X.Y., Jeong,Y.J., Jun,J.H. and Kim,N.H.
  TITLE     Gene expression of cox5a, 5b, or 6b1 and their roles in
            preimplantation mouse embryos
  JOURNAL   Biol Reprod 74 (3), 601-610 (2006)
   PUBMED   16291927
  REMARK    GeneRIF: gene expression of the Cox subunits, Cox5a, 5b, and 6b1 is
            not required for embryo developmental events up to the blastocyst
            stage
REFERENCE   6  (residues 1 to 86)
  AUTHORS   Grossman,L.I. and Lomax,M.I.
  TITLE     Nuclear genes for cytochrome c oxidase
  JOURNAL   Biochim Biophys Acta 1352 (2), 174-192 (1997)
   PUBMED   9199249
  REMARK    Review article
REFERENCE   7  (residues 1 to 86)
  AUTHORS   Stubbs,L., Carver,E.A., Shannon,M.E., Kim,J., Geisler,J.,
            Generoso,E.E., Stanford,B.G., Dunn,W.C., Mohrenweiser,H.,
            Zimmermann,W., Watt,S.M. and Ashworth,L.K.
  TITLE     Detailed comparative map of human chromosome 19q and related
            regions of the mouse genome
  JOURNAL   Genomics 35 (3), 499-508 (1996)
   PUBMED   8812484
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK007996.1 and AW047421.1.
            
            On Dec 7, 2005 this sequence version replaced XP_914756.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AV449586.1, BQ747274.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..86
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 18.84 cM"
     Protein         1..86
                     /product="cytochrome c oxidase subunit 6B1"
                     /EC_number="7.1.1.9"
                     /note="cytochrome c oxidase, subunit VIb polypeptide 1"
                     /calculated_mol_wt=9940
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0000250|UniProtKB:P00429; propagated from
                     UniProtKB/Swiss-Prot (P56391.2)"
     Region          8..85
                     /region_name="Cyt_c_Oxidase_VIb"
                     /note="Cytochrome c oxidase subunit VIb. Cytochrome c
                     oxidase (CcO), the terminal oxidase in the respiratory
                     chains of eukaryotes and most bacteria, is a multi-chain
                     transmembrane protein located in the inner membrane of
                     mitochondria and the cell membrane of...; cd00926"
                     /db_xref="CDD:238466"
     Site            order(12..15,24..27,59,62..68)
                     /site_type="other"
                     /note="Subunit VIb/II interface [polypeptide binding]"
                     /db_xref="CDD:238466"
     Site            24
                     /site_type="other"
                     /note="Subunit VIb/I interface [polypeptide binding]"
                     /db_xref="CDD:238466"
     Site            order(28,31,83)
                     /site_type="other"
                     /note="Subunit VIb/III interface [polypeptide binding]"
                     /db_xref="CDD:238466"
     Region          30..40
                     /region_name="Cx9C motif.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU01150"
                     /note="propagated from UniProtKB/Swiss-Prot (P56391.2)"
     Site            order(47,49..54)
                     /site_type="other"
                     /note="Subunit VIb/VIb interface [polypeptide binding]"
                     /db_xref="CDD:238466"
     Region          54..65
                     /region_name="Cx10C motif.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU01150"
                     /note="propagated from UniProtKB/Swiss-Prot (P56391.2)"
     Site            62
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:23576753; propagated from
                     UniProtKB/Swiss-Prot (P56391.2)"
     Site            order(76,79..81)
                     /site_type="other"
                     /note="Subunit VIb/VIa interface [polypeptide binding]"
                     /db_xref="CDD:238466"
     CDS             1..86
                     /gene="Cox6b1"
                     /gene_synonym="2010000G05Rik; COX VIb-1; Cox6b"
                     /coded_by="NM_025628.3:73..333"
                     /db_xref="CCDS:CCDS39887.1"
                     /db_xref="GeneID:110323"
                     /db_xref="MGI:MGI:107460"
ORIGIN      
        1 maediktkik nyktapfdsr fpnqnqtknc wqnyldfhrc ekamtakggd vsvcewyrrv
       61 ykslcpvswv sawddriaeg tfpgki
//
