LOCUS       NM_030205               3518 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus coronin 7 (Coro7), mRNA.
ACCESSION   NM_030205
VERSION     NM_030205.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3518)
  AUTHORS   Bhattacharya,K., Swaminathan,K., Peche,V.S., Clemen,C.S.,
            Knyphausen,P., Lammers,M., Noegel,A.A. and Rastetter,R.H.
  TITLE     Novel Coronin7 interactions with Cdc42 and N-WASP regulate actin
            organization and Golgi morphology
  JOURNAL   Sci Rep 6, 25411 (2016)
   PUBMED   27143109
  REMARK    GeneRIF: We conclude that CRN7 spatiotemporally influences F-actin
            organization and Golgi integrity in a Cdc42- and N-WASP-dependent
            manner.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3518)
  AUTHORS   Eriksson,A., Williams,M.J., Voisin,S., Hansson,I., Krishnan,A.,
            Philippot,G., Yamskova,O., Herisson,F.M., Dnyansagar,R.,
            Moschonis,G., Manios,Y., Chrousos,G.P., Olszewski,P.K.,
            Frediksson,R. and Schioth,H.B.
  TITLE     Implication of coronin 7 in body weight regulation in humans, mice
            and flies
  JOURNAL   BMC Neurosci 16, 13 (2015)
   PUBMED   25887538
  REMARK    GeneRIF: profiling of Coro7 mRNA expression revealed it is highly
            expressed in appetite and energy balance regulating regions of the
            brain; food deprivation downregulates hypothalamic Coro7 mRNA;
            conclude that coronin 7 is involved in the regulation of energy
            homeostasis and this role stems, to some degree, from the effect on
            feeding for calories and
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3518)
  AUTHORS   Suo,D., Park,J., Harrington,A.W., Zweifel,L.S., Mihalas,S. and
            Deppmann,C.D.
  TITLE     Coronin-1 is a neurotrophin endosomal effector that is required for
            developmental competition for survival
  JOURNAL   Nat Neurosci 17 (1), 36-45 (2014)
   PUBMED   24270184
REFERENCE   4  (bases 1 to 3518)
  AUTHORS   Watanabe,M., Suzuki,T., Kim,M., Abe,Y., Yoshida,Y., Sugano,S. and
            Yamamoto,T.
  TITLE     Coronin7 forms a novel E3 ubiquitin ligase complex to promote the
            degradation of the anti-proliferative protein Tob
  JOURNAL   FEBS Lett 585 (1), 65-70 (2011)
   PUBMED   21130766
REFERENCE   5  (bases 1 to 3518)
  AUTHORS   Rybakin,V., Stumpf,M., Schulze,A., Majoul,I.V., Noegel,A.A. and
            Hasse,A.
  TITLE     Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi
            apparatus
  JOURNAL   FEBS Lett 573 (1-3), 161-167 (2004)
   PUBMED   15327992
REFERENCE   6  (bases 1 to 3518)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 3518)
  AUTHORS   Phan,L.K., Lin,F., LeDuc,C.A., Chung,W.K. and Leibel,R.L.
  TITLE     The mouse mahoganoid coat color mutation disrupts a novel C3HC4
            RING domain protein
  JOURNAL   J Clin Invest 110 (10), 1449-1459 (2002)
   PUBMED   12438443
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC061006.1.
            
            On Jun 10, 2007 this sequence version replaced NM_030205.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061006.1, AK150051.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3518
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 2.45 cM"
     gene            1..3518
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /note="coronin 7"
                     /db_xref="GeneID:78885"
                     /db_xref="MGI:MGI:1926135"
     exon            1..169
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..2878
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /note="crn7; 70 kDa WD repeat tumor rejection antigen
                     homolog"
                     /codon_start=1
                     /product="coronin-7"
                     /protein_id="NP_084481.3"
                     /db_xref="CCDS:CCDS37242.1"
                     /db_xref="GeneID:78885"
                     /db_xref="MGI:MGI:1926135"
                     /translation="MSRFKVSKFRHMEARPSRREAWISDIRAVTTPTCGNHIKSSCSL
                     IAFNSDRPGVLGVISLEGHEENKRHVTYLGCHSDLVTDLDFSPFDDFLLASGSADRTI
                     KLWRLSGTGEALPSVPGVVLGPEELPVEVLQFHPTVDGVLVSTAGKTVKVWDVAKQQP
                     LTELEAHKDLVQSAVWSRDGAIVGTACKDKQLRIFDPRARTQASQSTQAHENNRDIRL
                     AWTGIQEHLVSTGFNQMREREAKLWDTRLFSSALASVTLDTSPGPLIPLLDPDSGLLV
                     LAGKGENQLYCYEVTPQQPALSPVTQCILENVLRGAALVPRRALAVMSCEVLQVLQLS
                     DTAIIPISHHVPRKAVEFHEDLFPDTAGSVPASDAHMWWAGDNQQVQKVSLNPARRPH
                     PCFTSSLVPTMEPAPDMVQPAEMPRADTDLSEGFSSPSSLMSPSTPSSLGPSLSSTSG
                     IGTSPSQRSLQSLLGPSSKFRHTQGSLLHRDSHITNLKGLNLTTPGESDGFCANRLRV
                     AVPLLSSGGQVAVLELQKPGRLPDTALPTLQNGTAVMDLVWDPFDPHRLAVAGEDARI
                     RLWRVPPGGLENVLTTPETVLTGHTEKIYSLRFHPLAADVLASSSYDLTVRIWDLQTG
                     AERLKLQGHQDQIFSLAWSPDGKQLATVCKDGHVRVYEPRSSPLPLQEGPGPEGGRGA
                     RIVWVCDGGCLLVSGFDSRSERQLQLYIADALAQGPSALLGLDVAPSTLLPSYDPDTG
                     LVLLTGKGDTRVFLYEVLPEAPFFLECNSFTSPDPHKGFVLLPKTECDIQDVEFARCL
                     RLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVTWEPALSAKAWFEGANGQPRLLSLQP
                     PGMTPVSQAPREVPARRAPSSAQYLEEKSDQQKKEELLNAMVAKLGNREDPLPQDSFE
                     GVDEDEWD"
     exon            170..266
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            267..341
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            342..412
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            413..596
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            597..673
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            674..724
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            725..811
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            812..894
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            895..949
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1007
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1153
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1246
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1378
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1502
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1678
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1679..1787
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1874
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..2017
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2018..2122
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2123..2208
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2209..2350
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2351..2440
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2441..2557
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2558..2693
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2694..2785
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2786..2872
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2873..3488
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3468..3473
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3488
                     /gene="Coro7"
                     /gene_synonym="0610011B16Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcaggctgct gaggcggcag gctgcaagag tccagggcgg cttctcttca ttcacctagt
       61 acctgacgac cctcgttctc cagcctgagc ttgctctgtc ccagctgcca tgagtcgctt
      121 caaggtgtcc aagtttcggc atatggaggc ccggccgtcc cgccgagagg cctggatcag
      181 tgatattcgt gctgtaacca cccccacatg cgggaaccac atcaaatcaa gctgcagctt
      241 gatcgctttc aactctgacc gcccaggtgt attgggtgtc atatctctgg aaggccatga
      301 ggaaaacaag aggcatgtga cctaccttgg ctgtcattca gacctggtca ctgacctgga
      361 cttctccccc tttgatgact tcctcctggc ctccggttca gctgacagga cgataaagct
      421 ttggcgtctg tctggcactg gagaagcgct tccctctgtg cctggagtgg tgctgggtcc
      481 tgaggagctg ccagtggagg tactgcagtt ccaccccact gtagacggtg ttctggtgag
      541 cacagctggc aagactgtga aggtctggga tgtagccaag cagcagcccc tgacagagtt
      601 ggaggcccac aaggacctgg tgcagagtgc tgtttggagc cgggatggag ccattgtggg
      661 cacagcatgt aaggacaagc agcttcggat ctttgacccc agagcaagaa cccaggcttc
      721 tcagagcaca caggcccatg agaacaacag agacatccgg ttggcatgga caggcattca
      781 agagcacctt gtgtccactg gattcaacca gatgcgtgag cgagaagcga agctctggga
      841 tacccggctc ttcagcagtg ccctggcctc cgtcaccctg gacacctctc ctgggcctct
      901 gatacctctg ctggatccag actctgggct attggtcctg gcaggaaagg gtgagaatca
      961 gctatactgt tacgaggtga ccccacagca gcctgcactg agcccagtga ctcagtgcat
     1021 tctggagaat gtactacgag gagcagccct tgttccccgg cgagcactgg ctgtcatgag
     1081 ttgcgaggtg ctccaagtcc tgcagctgag tgacacagcc atcataccca tcagccacca
     1141 cgtgccccga aaagctgtag agttccatga ggacctgttt ccagacacag ccggttctgt
     1201 gcctgcttct gatgcccaca tgtggtgggc tggggacaac cagcaggttc agaaggtcag
     1261 cctcaaccca gctcgccgac cccacccttg cttcacgtcc tccctggtgc ccactatgga
     1321 accggcccct gacatggtcc agcctgcaga gatgcccaga gctgacacag acctaagtga
     1381 gggcttttct tcccctagct cactgatgtc accctccaca ccatccagtc tggggccttc
     1441 actctccagc acgagcggca ttggtaccag ccccagtcag aggtcccttc agagtctgct
     1501 gggccccagt tctaaatttc gccacactca gggcagcctc ctccaccgcg acagtcacat
     1561 caccaacctt aagggactca acctcacaac acctggtgag agtgatggct tctgcgctaa
     1621 ccggctgcgt gtggctgttc ccctgctcag cagtggtggg caggtagctg tgcttgagct
     1681 gcagaagcca ggccgcctgc ctgacacagc attgcctaca cttcagaatg ggacagctgt
     1741 aatggatctg gtctgggatc cctttgaccc acaccggctt gctgtggctg gggaggatgc
     1801 ccggatccga ctatggcggg tgccccctgg tggcctcgag aatgttctca ccacacctga
     1861 gactgtgctc acaggccaca cagaaaagat ctactctctg cgcttccacc ccctggctgc
     1921 cgatgtactg gcttccagtt cctatgatct aaccgttcgc atctgggacc ttcagactgg
     1981 agctgagcgg ctgaaactgc agggccatca ggaccagatt tttagcttgg cctggagtcc
     2041 agatggaaag caactggcca ccgtatgcaa ggatgggcat gtgcgggtct atgaaccccg
     2101 cagcagccct ttacccctac aggaaggccc aggacctgaa ggtggccgcg gagcccgcat
     2161 tgtctgggtg tgtgatggtg gttgcctgct ggtttctggc tttgacagcc ggagtgaacg
     2221 ccagctacag ttgtacatag ctgacgccct ggcacaaggc ccttcagcac tgctgggcct
     2281 cgatgtagct ccctcgaccc tgcttcccag ctatgaccct gacacaggcc tggtgcttct
     2341 cactggcaag ggtgataccc gtgtgttcct gtatgaggtg ctcccggagg cccctttctt
     2401 cctggagtgc aacagcttca catcacctga ccctcacaag ggttttgtcc ttctgcccaa
     2461 gactgagtgt gacattcagg atgtggagtt tgcccgatgc ctgcggctgc gccagacctc
     2521 cttggagcct gttgctttcc ggctgccccg ggtcagaaaa gaattcttcc aggatgatgt
     2581 gttcccggac acagctgtga cctgggagcc agcactcagt gccaaagcct ggtttgaggg
     2641 tgctaatgga cagccccggc tactgagttt gcagccccct ggcatgaccc cagtgagcca
     2701 ggccccccgt gaggtccctg cccgaagagc cccatcttca gcacaatact tggaagagaa
     2761 gtctgaccaa caaaagaaag aagagctgct gaatgccatg gtagcaaagc tggggaaccg
     2821 agaagaccca ctgccacagg actcctttga aggggtggat gaagatgagt gggactagcc
     2881 tgcacgcgag gcacgcctaa tcacagctgc cactgccacc tcctacaact acctgctgcc
     2941 ctccacacct aagatctctg caacctggac aatgctgcac tggccctggc acgcacatcc
     3001 agctcagaag ccctgggtgt cacgcaagcc tcaggcactt ccacagctgt ggggcctcca
     3061 tgcagctgca gagactgcct gctccttaac cctctggagc caactgttta tcttcagctg
     3121 cctgttagca tgtgacacca gtgggtggga ggtaggtgtc agtagcatgt ctctgggcca
     3181 actcgggatg ccctgtctct cccagtcttt ctgctggttt cctctaatat cttcagttac
     3241 tacaagccaa gctgtcttgc ctactgcacc agccccagtc aaggacactg ggggctggtc
     3301 ccccaccaag ctgttgggag ccgctttctc cttaggggcc taggaccatt tgtcctgctt
     3361 ctcctggctt gaggagaaag ggtctcatgg cgctaacagc ctcattacag tggtgtggac
     3421 cccataacaa acagcctata taggatatgc tctggatgtt tccagcaatt aaacttttct
     3481 aagctggcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
