LOCUS       NM_011779               3436 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus coronin, actin binding protein 1C (Coro1c), mRNA.
ACCESSION   NM_011779
VERSION     NM_011779.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3436)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3436)
  AUTHORS   King,Z.T., Butler,M.T., Hockenberry,M.A., Subramanian,B.C.,
            Siesser,P.F., Graham,D.M., Legant,W.R. and Bear,J.E.
  TITLE     Coro1B and Coro1C regulate lamellipodia dynamics and cell motility
            by tuning branched actin turnover
  JOURNAL   J Cell Biol 221 (8) (2022)
   PUBMED   35657370
  REMARK    GeneRIF: Coro1B and Coro1C regulate lamellipodia dynamics and cell
            motility by tuning branched actin turnover.
REFERENCE   3  (bases 1 to 3436)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3436)
  AUTHORS   Tagliatela,A.C., Hempstead,S.C., Hibshman,P.S., Hockenberry,M.A.,
            Brighton,H.E., Pecot,C.V. and Bear,J.E.
  TITLE     Coronin 1C inhibits melanoma metastasis through regulation of
            MT1-MMP-containing extracellular vesicle secretion
  JOURNAL   Sci Rep 10 (1), 11958 (2020)
   PUBMED   32686704
  REMARK    GeneRIF: Coronin 1C inhibits melanoma metastasis through regulation
            of MT1-MMP-containing extracellular vesicle secretion.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3436)
  AUTHORS   Solga,R., Behrens,J., Ziemann,A., Riou,A., Berwanger,C., Becker,L.,
            Garrett,L., de Angelis,M.H., Fischer,L., Coras,R., Barkovits,K.,
            Marcus,K., Mahabir,E., Eichinger,L., Schroder,R., Noegel,A.A. and
            Clemen,C.S.
  CONSRTM   German Mouse Clinic Consortium
  TITLE     CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of
            glioblastoma cells
  JOURNAL   Eur J Cell Biol 98 (5-8), 151046 (2019)
   PUBMED   31677819
  REMARK    GeneRIF: The results imply that CRN2 represents a pro-invasive
            effector within the tumour cell microenvironment of glioblastoma
            multiforme.
REFERENCE   6  (bases 1 to 3436)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
REFERENCE   7  (bases 1 to 3436)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 3436)
  AUTHORS   Spoerl,Z., Stumpf,M., Noegel,A.A. and Hasse,A.
  TITLE     Oligomerization, F-actin interaction, and membrane association of
            the ubiquitous mammalian coronin 3 are mediated by its carboxyl
            terminus
  JOURNAL   J Biol Chem 277 (50), 48858-48867 (2002)
   PUBMED   12377779
REFERENCE   9  (bases 1 to 3436)
  AUTHORS   de Hostos,E.L.
  TITLE     The coronin family of actin-associated proteins
  JOURNAL   Trends Cell Biol 9 (9), 345-350 (1999)
   PUBMED   10461187
  REMARK    Review article
REFERENCE   10 (bases 1 to 3436)
  AUTHORS   Okumura,M., Kung,C., Wong,S., Rodgers,M. and Thomas,M.L.
  TITLE     Definition of family of coronin-related proteins conserved between
            humans and mice: close genetic linkage between coronin-2 and
            CD45-associated protein
  JOURNAL   DNA Cell Biol 17 (9), 779-787 (1998)
   PUBMED   9778037
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK082986.1.
            
            On Apr 6, 2007 this sequence version replaced NM_011779.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077552.1, AK082986.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3436              AK082986.1         3-3438
FEATURES             Location/Qualifiers
     source          1..3436
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 55.64 cM"
     gene            1..3436
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /note="coronin, actin binding protein 1C"
                     /db_xref="GeneID:23790"
                     /db_xref="MGI:MGI:1345964"
     exon            1..96
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            97..296
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..1526
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /note="coronin-3; coronin 1c"
                     /codon_start=1
                     /product="coronin-1C"
                     /protein_id="NP_035909.2"
                     /db_xref="CCDS:CCDS19555.1"
                     /db_xref="GeneID:23790"
                     /db_xref="MGI:MGI:1345964"
                     /translation="MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPR
                     FVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSED
                     CTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV
                     GTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEG
                     ARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPD
                     TSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIAR
                     FFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISLKH
                     GYIPGKNRDLKVVKKNILDSKPAANKKSELSCAPKKPTDTASVQNEAKLDEILKEIKS
                     IKETICSQDERISKLEQQLAKMAA"
     exon            297..419
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            420..549
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            550..731
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            732..851
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            852..956
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            957..1102
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1160
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1406
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..3436
                     /gene="Coro1c"
                     /gene_synonym="CRN2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcgctca gtgccaggcg ggaggcggca gcggttggag gcttcgcggg gctttgcagc
       61 agggacttcg gcggcgcctc aggcacccgg gctctgacac gatgcggcga gtggtgcggc
      121 agagcaagtt ccgccacgtc tttggacagg cggtgaagaa tgaccagtgc tatgacgaca
      181 tccgtgtctc ccgagtcacc tgggacagtt ccttttgtgc cgtcaacccc agattcgtgg
      241 ccatcatcat agaagcgagt gggggagggg ccttcctggt gctccctctg cacaagacgg
      301 gacgaattga caaatcctac cctacagtgt gtggccacac aggaccagtg ctggacatag
      361 actggtgtcc acataatgac caggtcattg ccagcggctc agaggactgc actgttatgg
      421 tttggcagat cccggaaaat ggactcaccc tttccctgac cgagcctgtg gtgattctag
      481 aagggcactc aaaaagagtt ggcatcgtgg cctggcaccc gacggcccgc aatgtgcttc
      541 tcagtgcagg ctgtgataat gccattatca tctggaacgt ggggacaggg gaagccctca
      601 tcaacttgga cgatatgcat tcagacatga tttacaatgt gagctggagc cgtaacggta
      661 gtctcatctg caccgcatcc aaagacaaga aagtgagagt cattgacccc aggaaacagg
      721 agattgtggc ggagaaggag aaagcacacg aaggagccag gcctatgcgt gccatcttcc
      781 tggcggacgg caacgtcttc actactggct ttagccgcat gagcgagcgg cagttggcgc
      841 tctggaaccc aaaaaacatg caggaaccaa ttgctctcca tgaaatggac actagcaatg
      901 gggtgctgct ccccttctac gatccggaca ccagcatcat ctacttatgt gggaagggtg
      961 acagcagtat ccgctatttt gagatcacgg atgaatcccc atatgtccac tacctcaaca
     1021 cattcagcag caaggagcct cagcgaggga tgggctacat gcccaagcgg ggccttgacg
     1081 tcaacaagtg tgaaattgcc agattcttca agcttcatga gagaaagtgc gagcccatta
     1141 tcatgacggt ccccaggaag tctgacctct tccaagacga cctgtaccct gacacggcag
     1201 ggccggaagc cgcccttgag gccgaggagt ggtttgaggg gaagaacgcg gaccccatcc
     1261 tcatatcgtt gaagcacggg tacattccag gcaagaacag ggacctcaag gtggtcaaga
     1321 agaacatcct ggacagcaag ccggctgcaa acaagaagag cgagctcagc tgtgccccca
     1381 agaagcccac agacacggcc agtgtgcaaa acgaagccaa gttggatgag attctgaaag
     1441 agatcaaatc cataaaggaa acaatctgca gtcaagacga gcgcatttcc aagttggagc
     1501 agcagctggc gaagatggct gcctgaggcc cgcccacctc cacggacggt ggctgctcct
     1561 cctccgcgca ctcccaggga gggcagagag ggagacactg ccatttggag acattccatg
     1621 tcagatctgt cagccagcga taggccacat tccagtaaga actcggttcc tctcccaaat
     1681 ttccgcaaac ctggaagctg agcttttcgt cagggagctt tggtgttcgg caggtctgct
     1741 gacttgctga gctttcctac gtttgaaatg ccagatgttc tgaattttag agaccaagcc
     1801 ccccacttga cccagcgtcc tcctcacaca cctgatgacc gggccagcgc cacctctgct
     1861 ctgtctcttc ctttttaatg ttgccaaaac cgaaagtagc ttttttttct ttgtattttt
     1921 ctactttgca gtatttgtgg ggtttctttc tttctttctt tctttctttc tttctttctt
     1981 tctttctttc tttctttctt ttctctcctc aatttaaaag ggacagcact gtgtatgttt
     2041 ataaactaaa tgaagatgag atgattattt tgtataaaca ctcacgagaa caatcagtgc
     2101 agccgcctgc acagggctgg ctcactcaca gcacaaacct gggcgttagt ctaacgactg
     2161 tgcagaagga agacttgaga aatcacgtgg acccaccaca cactgccccc attccattga
     2221 gtcttcgatc aaaagtcctg tctctctctc tccttgctct ctctctccta gaagttgggt
     2281 ggttgcacag agggaactcg gtgattatac tctaacccga actagctcgc gtttctgcag
     2341 ttttgttctc cacagatggt tgtgcctgtc ccttccagca gtgtggttcc cttccgggca
     2401 gtttggacaa gggcacccaa ggcgagcgga tacctgtgtg ttgacagtcc ttgtctacag
     2461 aggcagcttg cctggccctt gggtatagtg tggggcttga acccaggcac tgtgtgcaca
     2521 gcctctgccc caggccctct gtttccctcg ctcctgtctt ccctccttac tttgctgcct
     2581 cctgtctcaa gcgcccagcc agccctcgag ggctcttgaa tgttgcagcg gagggaaagg
     2641 tccagaacag agtggaaagg gaagttcaga gatcgaccat agctggccac gcacaggccc
     2701 tctgccccac cacccagatc aggctgctac ttgccagcac tggacgtgcc ctgggcatgc
     2761 ctgctccaag ggcagcagct agaccttagc cctactctaa cctcacagcc tcatggtgcg
     2821 tgtctatgga agcagacgac ctgggtagtg tcagatggat cacaaaaggc aagccttggc
     2881 aagtgttggt gctggtgtgg gcccagtgct ggctgccagc aaatgtacag gttatcaggg
     2941 cagagcatag tatggcagca gccgcttaga gtgtgtggac tgactgggta gtgttgtaag
     3001 aaaaggttct ctcagccacc gagatggggg ccgctggctc cgaagcttcg gggctcctga
     3061 gtctctgtag gtttctgtgt ctgtcttgtg gtttaatgtt ggataaggag atggagagac
     3121 catggctgga atgactcaca ctgcattgtc tgtacgtgtg ctacgctgag gactgtgtga
     3181 agattcacaa aggttctggg gtccgttgaa ttaattacgt aacaattgta gaggctgttg
     3241 atgaagtcag aggggctgtg gttgagagag gcgggagtga ctgtagtgtg tgcccacctg
     3301 acacgctgtg gtggcctctg tttccctgtg gcaccggagg aagacagtga actgctccta
     3361 cacccactct tatagagtgg ccatagtgtt ctgtcaaaac actcgcttcc gttttcagag
     3421 ataaaaggca ttgatt
//
