LOCUS       NM_011778               1853 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus coronin, actin binding protein 1B (Coro1b), transcript
            variant 1, mRNA.
ACCESSION   NM_011778
VERSION     NM_011778.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1853)
  AUTHORS   King,Z.T., Butler,M.T., Hockenberry,M.A., Subramanian,B.C.,
            Siesser,P.F., Graham,D.M., Legant,W.R. and Bear,J.E.
  TITLE     Coro1B and Coro1C regulate lamellipodia dynamics and cell motility
            by tuning branched actin turnover
  JOURNAL   J Cell Biol 221 (8) (2022)
   PUBMED   35657370
  REMARK    GeneRIF: Coro1B and Coro1C regulate lamellipodia dynamics and cell
            motility by tuning branched actin turnover.
REFERENCE   2  (bases 1 to 1853)
  AUTHORS   Koopmans,F., van Nierop,P., Andres-Alonso,M., Byrnes,A.,
            Cijsouw,T., Coba,M.P., Cornelisse,L.N., Farrell,R.J.,
            Goldschmidt,H.L., Howrigan,D.P., Hussain,N.K., Imig,C., de
            Jong,A.P.H., Jung,H., Kohansalnodehi,M., Kramarz,B., Lipstein,N.,
            Lovering,R.C., MacGillavry,H., Mariano,V., Mi,H., Ninov,M.,
            Osumi-Sutherland,D., Pielot,R., Smalla,K.H., Tang,H., Tashman,K.,
            Toonen,R.F.G., Verpelli,C., Reig-Viader,R., Watanabe,K., van
            Weering,J., Achsel,T., Ashrafi,G., Asi,N., Brown,T.C., De
            Camilli,P., Feuermann,M., Foulger,R.E., Gaudet,P., Joglekar,A.,
            Kanellopoulos,A., Malenka,R., Nicoll,R.A., Pulido,C., de
            Juan-Sanz,J., Sheng,M., Sudhof,T.C., Tilgner,H.U., Bagni,C.,
            Bayes,A., Biederer,T., Brose,N., Chua,J.J.E., Dieterich,D.C.,
            Gundelfinger,E.D., Hoogenraad,C., Huganir,R.L., Jahn,R.,
            Kaeser,P.S., Kim,E., Kreutz,M.R., McPherson,P.S., Neale,B.M.,
            O'Connor,V., Posthuma,D., Ryan,T.A., Sala,C., Feng,G., Hyman,S.E.,
            Thomas,P.D., Smit,A.B. and Verhage,M.
  TITLE     SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the
            Synapse
  JOURNAL   Neuron 103 (2), 217-234 (2019)
   PUBMED   31171447
REFERENCE   3  (bases 1 to 1853)
  AUTHORS   Jansen,S., Collins,A., Chin,S.M., Ydenberg,C.A., Gelles,J. and
            Goode,B.L.
  TITLE     Single-molecule imaging of a three-component ordered actin
            disassembly mechanism
  JOURNAL   Nat Commun 6, 7202 (2015)
   PUBMED   25995115
  REMARK    GeneRIF: Cor1B, Cof1 and AIP1 work in concert through a temporally
            ordered pathway to induce highly efficient severing and disassembly
            of actin filaments.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1853)
  AUTHORS   Suo,D., Park,J., Harrington,A.W., Zweifel,L.S., Mihalas,S. and
            Deppmann,C.D.
  TITLE     Coronin-1 is a neurotrophin endosomal effector that is required for
            developmental competition for survival
  JOURNAL   Nat Neurosci 17 (1), 36-45 (2014)
   PUBMED   24270184
REFERENCE   5  (bases 1 to 1853)
  AUTHORS   Hsu,W.H., Yu,Y.R., Hsu,S.H., Yu,W.C., Chu,Y.H., Chen,Y.J.,
            Chen,C.M. and You,L.R.
  TITLE     The Wilms' tumor suppressor Wt1 regulates Coronin 1B expression in
            the epicardium
  JOURNAL   Exp Cell Res 319 (10), 1365-1381 (2013)
   PUBMED   23562652
  REMARK    GeneRIF: Wt1 is a transcriptional activator of Coro1b gene.
REFERENCE   6  (bases 1 to 1853)
  AUTHORS   Foger,N., Jenckel,A., Orinska,Z., Lee,K.H., Chan,A.C. and
            Bulfone-Paus,S.
  TITLE     Differential regulation of mast cell degranulation versus cytokine
            secretion by the actin regulatory proteins Coronin1a and Coronin1b
  JOURNAL   J Exp Med 208 (9), 1777-1787 (2011)
   PUBMED   21844203
  REMARK    GeneRIF: Differential regulation of mast cell degranulation versus
            cytokine secretion by the actin regulatory proteins Coronin1a and
            Coronin1b.
REFERENCE   7  (bases 1 to 1853)
  AUTHORS   Shiow,L.R., Roadcap,D.W., Paris,K., Watson,S.R., Grigorova,I.L.,
            Lebet,T., An,J., Xu,Y., Jenne,C.N., Foger,N., Sorensen,R.U.,
            Goodnow,C.C., Bear,J.E., Puck,J.M. and Cyster,J.G.
  TITLE     The actin regulator coronin 1A is mutant in a thymic
            egress-deficient mouse strain and in a patient with severe combined
            immunodeficiency
  JOURNAL   Nat Immunol 9 (11), 1307-1315 (2008)
   PUBMED   18836449
REFERENCE   8  (bases 1 to 1853)
  AUTHORS   Cai,L., Holoweckyj,N., Schaller,M.D. and Bear,J.E.
  TITLE     Phosphorylation of coronin 1B by protein kinase C regulates
            interaction with Arp2/3 and cell motility
  JOURNAL   J Biol Chem 280 (36), 31913-31923 (2005)
   PUBMED   16027158
REFERENCE   9  (bases 1 to 1853)
  AUTHORS   de Hostos,E.L.
  TITLE     The coronin family of actin-associated proteins
  JOURNAL   Trends Cell Biol 9 (9), 345-350 (1999)
   PUBMED   10461187
  REMARK    Review article
REFERENCE   10 (bases 1 to 1853)
  AUTHORS   Okumura,M., Kung,C., Wong,S., Rodgers,M. and Thomas,M.L.
  TITLE     Definition of family of coronin-related proteins conserved between
            humans and mice: close genetic linkage between coronin-2 and
            CD45-associated protein
  JOURNAL   DNA Cell Biol 17 (9), 779-787 (1998)
   PUBMED   9778037
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109138.10.
            
            On Feb 1, 2019 this sequence version replaced NM_011778.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC029326.1, AF143956.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                AC109138.10        157072-157154
            84-286              AC109138.10        157760-157962
            287-409             AC109138.10        158281-158403
            410-539             AC109138.10        158508-158637
            540-721             AC109138.10        158858-159039
            722-841             AC109138.10        159125-159244
            842-946             AC109138.10        159813-159917
            947-1092            AC109138.10        159998-160143
            1093-1150           AC109138.10        160940-160997
            1151-1414           AC109138.10        161645-161908
            1415-1853           AC109138.10        162015-162453
FEATURES             Location/Qualifiers
     source          1..1853
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 3.85 cM"
     gene            1..1853
                     /gene="Coro1b"
                     /note="coronin, actin binding protein 1B"
                     /db_xref="GeneID:23789"
                     /db_xref="MGI:MGI:1345963"
     exon            1..83
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     exon            84..286
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             86..1540
                     /gene="Coro1b"
                     /note="coronin-2; coronin 1b"
                     /codon_start=1
                     /product="coronin-1B"
                     /protein_id="NP_035908.1"
                     /db_xref="CCDS:CCDS29418.1"
                     /db_xref="GeneID:23789"
                     /db_xref="MGI:MGI:1345963"
                     /translation="MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVN
                     PKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGS
                     EDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIW
                     NVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAH
                     EGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYD
                     PDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEI
                     ARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEDWVSGQDANPILISL
                     REAYVPSKQRDLKVSRRNVLSDSRPASYSRSGASTATAVTDVPSGNLAGAGEAGKLEE
                     VMQELRALRMLVKEQGERISRLEEQLGRMENGDT"
     exon            287..409
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     exon            410..539
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     exon            540..721
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     exon            722..841
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     exon            842..946
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     exon            947..1092
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1150
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1414
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1853
                     /gene="Coro1b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1830..1835
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Coro1b"
                     /note="hexamer: AATAAA"
     polyA_site      1853
                     /gene="Coro1b"
                     /note="major polyA site"
ORIGIN      
        1 agaggccggg atccggagcc gcccgaggtc gccgccgcag tccccggcgc ccctggggag
       61 cggagagcgg tgagcggtga gcgacatgtc cttccgaaaa gttgtgcggc agagcaaatt
      121 ccggcatgta ttcggtcagc cggtcaagaa tgaccagtgc tatgaggaca ttcgagtgtc
      181 ccgagttacc tgggacagca ccttctgcgc agtcaacccc aagttcctgg cagtgattgt
      241 ggaagccagt ggtggaggcg cctttatggt gcttcctcta aacaagacgg gccgcattga
      301 caaggcctac ccgacagtgt gtgggcacac ggggcctgtt ctggatattg actggtgtcc
      361 ccacaatgat gaagtcattg ccagtggatc agaggactgc actgtcatgg tatggcagat
      421 tccagaaaat gggctgacct cccctctgac agagccagta gtggtgctcg aggggcatac
      481 caagcgcgtg ggcattatca cctggcaccc cacagcccga aatgtgcttc tcagtgcagg
      541 ttgtgacaat gtggtactta tctggaatgt gggcactgca gaggagctgt accgtctgga
      601 cagcttgcac cccgacctca tctacaacgt gagctggaac cacaatggca gcctcttttg
      661 ctcagcttgc aaggacaaga gcgtccgaat catcgatcct aggcggggca ccctggtggc
      721 agaacgtgaa aaggctcacg agggggcccg gcccatgcgg gccatctttc tagctgacgg
      781 gaaggtgttc accacaggtt tcagccgcat gagtgaacgg cagctggcgc tctgggaccc
      841 agaaaacctt gaggagccca tggccctgca ggagctggat tcaagcaatg gggctctact
      901 gcccttttat gacccagaca ccagtgtggt ctatgtctgt ggcaagggcg attccagcat
      961 ccggtacttt gagatcacag atgagccccc ctacatccac ttcctgaata catttaccag
     1021 caaagaaccc cagaggggta tgggcagcat gcctaagagg ggcttggagg tcagcaagtg
     1081 tgaaattgcc aggttctaca aactgcatga acgcaagtgt gagcccatag tcatgactgt
     1141 gccaagaaag tctgacctct tccaggatga tctgtaccct gacacagccg ggcctgaggc
     1201 tgctcttgaa gcagaggatt gggtgagcgg tcaggatgct aatccaatcc tcatctcact
     1261 acgggaagcc tatgtgccca gtaaacaacg ggacctgaag gtcagccggc gcaacgtgct
     1321 atcagacagc aggcctgcca gttacagccg ctccggagcc tccacagcta ctgcagttac
     1381 tgatgtcccc agtggcaacc ttgctggggc tggtgaagct gggaagctgg aagaggtgat
     1441 gcaggagctc cgggcactcc ggatgctggt caaggagcag ggagaacgta tcagccgcct
     1501 ggaggagcag ctgggccgca tggagaatgg ggatacatag gaccaccagg gacctgctcc
     1561 cgacactgcc tcctccaacc cttcccacct agcttctgtg gccaggtcac accaggcagt
     1621 tggctgctca gtgcctctgt ggcaggtcac agccagtttg cacctctcca cagcctgggg
     1681 cccaggttgg aagcaccacc tgacttttgg aagatttttg taccaaggca aattcccaag
     1741 tactttaagg gaccatctcc tcgacctgcc caacccactg ccccctcacc agaaaaagca
     1801 gcagagatgg ggtctatatt ttcattccaa ataaaatgct ctttctaaag cca
//
