LOCUS       NP_001399177             461 aa            linear   ROD 02-MAY-2024
DEFINITION  coronin-1A [Mus musculus].
ACCESSION   NP_001399177
VERSION     NP_001399177.1
DBSOURCE    REFSEQ: accession NM_001412248.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 461)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 461)
  AUTHORS   Deng,X., Liu,B., Jiang,Q., Li,G., Li,J. and Xu,K.
  TITLE     CREBH promotes autophagy to ameliorate NASH by regulating Coro1a
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1870 (1), 166914 (2024)
   PUBMED   37837948
REFERENCE   3  (residues 1 to 461)
  AUTHORS   Wang,F., Tan,P., Zhang,P., Ren,Y., Zhou,J., Li,Y., Hou,S., Li,S.,
            Zhang,L., Ma,Y., Wang,C., Tang,W., Wang,X., Huo,Y., Hu,Y., Cui,T.,
            Niu,C., Wang,D., Liu,B., Lan,Y. and Yu,J.
  TITLE     Single-cell architecture and functional requirement of alternative
            splicing during hematopoietic stem cell formation
  JOURNAL   Sci Adv 8 (1), eabg5369 (2022)
   PUBMED   34995116
REFERENCE   4  (residues 1 to 461)
  AUTHORS   Fei,X., Li,Z., Yang,D., Kong,X., Lu,X., Shen,Y., Li,X., Xie,S.,
            Wang,J., Zhao,Y., Sun,Y., Zhang,J., Ye,Z., Wang,J. and Cai,Z.
  TITLE     Neddylation of Coro1a determines the fate of multivesicular bodies
            and biogenesis of extracellular vesicles
  JOURNAL   J Extracell Vesicles 10 (12), e12153 (2021)
   PUBMED   34623756
  REMARK    GeneRIF: Neddylation of Coro1a determines the fate of
            multivesicular bodies and biogenesis of extracellular vesicles.
REFERENCE   5  (residues 1 to 461)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 461)
  AUTHORS   Okumura,M., Kung,C., Wong,S., Rodgers,M. and Thomas,M.L.
  TITLE     Definition of family of coronin-related proteins conserved between
            humans and mice: close genetic linkage between coronin-2 and
            CD45-associated protein
  JOURNAL   DNA Cell Biol 17 (9), 779-787 (1998)
   PUBMED   9778037
REFERENCE   7  (residues 1 to 461)
  AUTHORS   Vidal,S., Kono,D.H. and Theofilopoulos,A.N.
  TITLE     Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr
            mice
  JOURNAL   J Clin Invest 101 (3), 696-702 (1998)
   PUBMED   9449705
REFERENCE   8  (residues 1 to 461)
  AUTHORS   Kimura,S., Hirasawa,T., Nakamura,K., Yagi,H., Matsumoto,M.,
            Makino,S. and Harada,M.
  TITLE     Genetic control of peripheral T-cell deficiency in the cataract
            Shionogi (CTS) mouse linked to chromosome 7
  JOURNAL   Immunogenetics 47 (3), 278-280 (1998)
   PUBMED   9435347
REFERENCE   9  (residues 1 to 461)
  AUTHORS   Yagi,H., Matsumoto,M., Nakamura,M., Makino,S., Suzuki,R., Harada,M.
            and Itoh,T.
  TITLE     Defect of thymocyte emigration in a T cell deficiency strain (CTS)
            of the mouse
  JOURNAL   J Immunol 157 (8), 3412-3419 (1996)
   PUBMED   8871639
REFERENCE   10 (residues 1 to 461)
  AUTHORS   Yagi,H., Nagata,M., Takeuchi,M., Watanabe,A., Arimura,A.,
            Hashimoto,S., Makino,S. and Harada,M.
  TITLE     Immune deficiency of cataract Shionogi (CTS) mouse. II. Impaired in
            vivo T cell-mediated immune response
  JOURNAL   Immunol Invest 19 (5-6), 493-505 (1990)
   PUBMED   2074115
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC124505.4.
            
            Summary: This gene encodes a member of the WD repeat coronin
            family. The encoded protein may bind actin and interact with
            microtubules. Alternative splicing results in multiple transcript
            variants. [provided by RefSeq, Aug 2014].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422598.847891.1,
                                           SRR13422600.124163.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 69.25 cM"
     Protein         1..461
                     /product="coronin-1A"
                     /note="clipin-A; coronin-like protein A; coronin-like
                     protein p57; tryptophan aspartate-containing coat protein;
                     coronin-like actin binding protein; coronin 1"
                     /calculated_mol_wt=50858
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylserine.
                     /evidence=ECO:0000250|UniProtKB:P31146; propagated from
                     UniProtKB/Swiss-Prot (O89053.5)"
     Site            2
                     /site_type="phosphorylation"
                     /note="Phosphoserine, by PKC.
                     /evidence=ECO:0000250|UniProtKB:P31146; propagated from
                     UniProtKB/Swiss-Prot (O89053.5)"
     Region          9..461
                     /region_name="WD40"
                     /note="WD40 domain, found in a number of eukaryotic
                     proteins that cover a wide variety of functions including
                     adaptor/regulatory modules in signal transduction,
                     pre-mRNA processing and cytoskeleton assembly; typically
                     contains a GH dipeptide 11-24 residues from...; cl29593"
                     /db_xref="CDD:475233"
     Region          13..63
                     /region_name="WD 1.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00221,
                     ECO:0000269|PubMed:16407068"
                     /note="propagated from UniProtKB/Swiss-Prot (O89053.5)"
     Region          37..79
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          73..110
                     /region_name="WD 2.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00221,
                     ECO:0000269|PubMed:16407068"
                     /note="propagated from UniProtKB/Swiss-Prot (O89053.5)"
     Region          85..129
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          123..160
                     /region_name="WD 3.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00221,
                     ECO:0000269|PubMed:16407068"
                     /note="propagated from UniProtKB/Swiss-Prot (O89053.5)"
     Region          134..171
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          164..204
                     /region_name="WD 4.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00221,
                     ECO:0000269|PubMed:16407068"
                     /note="propagated from UniProtKB/Swiss-Prot (O89053.5)"
     Region          180..215
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          207..251
                     /region_name="WD 5.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00221,
                     ECO:0000269|PubMed:16407068"
                     /note="propagated from UniProtKB/Swiss-Prot (O89053.5)"
     Region          223..263
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          258..296
                     /region_name="WD 6.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00221,
                     ECO:0000269|PubMed:16407068"
                     /note="propagated from UniProtKB/Swiss-Prot (O89053.5)"
     Region          270..311
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          302..349
                     /region_name="WD 7.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU00221,
                     ECO:0000269|PubMed:16407068"
                     /note="propagated from UniProtKB/Swiss-Prot (O89053.5)"
     Region          403..434
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (O89053.5)"
     Site            412
                     /site_type="phosphorylation"
                     /note="Phosphoserine, by PKC.
                     /evidence=ECO:0000269|PubMed:23100250; propagated from
                     UniProtKB/Swiss-Prot (O89053.5)"
     Site            418
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:19144319,
                     ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (O89053.5)"
     Site            422
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (O89053.5)"
     CDS             1..461
                     /gene="Coro1a"
                     /gene_synonym="Clabp; Lmb3; p57; TACO"
                     /coded_by="NM_001412248.1:242..1627"
                     /db_xref="GeneID:12721"
                     /db_xref="MGI:MGI:1345961"
ORIGIN      
        1 msrqvvrssk frhvfgqpak adqcyedvrv sqttwdsgfc avnpkfmali ceasgggafl
       61 vlplgktgrv dknvplvcgh tapvldiawc phndnviasg sedctvmvwe ipdgglvlpl
      121 repvitlegh tkrvgivawh ptaqnvllsa gcdnvilvwd vgtgaavltl gpdvhpdtiy
      181 svdwsrdgal ictscrdkrv rvieprkgtv vaekdrpheg trpvhavfvs egkilttgfs
      241 rmserqvalw dtkhleepls lqeldtssgv llpffdpdtn ivylcgkgds siryfeitse
      301 apflhylsmf sskesqrgmg ympkrglevn kceiarfykl herkcepiam tvprksdlfq
      361 edlypptagp dpaltaeewl ggrdagplli slkdgyvppk srelrvnrgl dsarrratpe
      421 psgtpssdtv srleedvrnl naivqklqer ldrleetvqa k
//
