LOCUS       NM_017478               4000 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus coatomer protein complex, subunit gamma 2 (Copg2),
            transcript variant 1, mRNA.
ACCESSION   NM_017478
VERSION     NM_017478.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4000)
  AUTHORS   Kuliyev,E., Gingras,S., Guy,C.S., Howell,S., Vogel,P. and
            Pelletier,S.
  TITLE     Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron
            Viability
  JOURNAL   J Neurosci 38 (10), 2615-2630 (2018)
   PUBMED   29437892
REFERENCE   2  (bases 1 to 4000)
  AUTHORS   Liu,L., Fujino,K. and Nishimura,M.
  TITLE     Pre-synaptic localization of the gamma-secretase-inhibiting protein
            p24alpha2 in the mammalian brain
  JOURNAL   J Neurochem 133 (3), 422-431 (2015)
   PUBMED   25438880
REFERENCE   3  (bases 1 to 4000)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   4  (bases 1 to 4000)
  AUTHORS   Seibt,J., Armant,O., Le Digarcher,A., Castro,D., Ramesh,V.,
            Journot,L., Guillemot,F., Vanderhaeghen,P. and Bouschet,T.
  TITLE     Expression at the imprinted dlk1-gtl2 locus is regulated by
            proneural genes in the developing telencephalon
  JOURNAL   PLoS One 7 (11), e48675 (2012)
   PUBMED   23139813
REFERENCE   5  (bases 1 to 4000)
  AUTHORS   Peter,C.J., Evans,M., Thayanithy,V., Taniguchi-Ishigaki,N.,
            Bach,I., Kolpak,A., Bassell,G.J., Rossoll,W., Lorson,C.L., Bao,Z.Z.
            and Androphy,E.J.
  TITLE     The COPI vesicle complex binds and moves with survival motor neuron
            within axons
  JOURNAL   Hum Mol Genet 20 (9), 1701-1711 (2011)
   PUBMED   21300694
REFERENCE   6  (bases 1 to 4000)
  AUTHORS   Yun,J., Park,C.W., Lee,Y.J. and Chung,J.H.
  TITLE     Allele-specific methylation at the promoter-associated CpG island
            of mouse Copg2
  JOURNAL   Mamm Genome 14 (6), 376-382 (2003)
   PUBMED   12879359
REFERENCE   7  (bases 1 to 4000)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 4000)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   9  (bases 1 to 4000)
  AUTHORS   Chow,V.T., Sakharkar,M.K., Lim,D.P. and Yeo,W.M.
  TITLE     Phylogenetic relationships of the seven coat protein subunits of
            the coatomer complex, and comparative sequence analysis of murine
            xenin and proxenin
  JOURNAL   Biochem Genet 39 (5-6), 201-211 (2001)
   PUBMED   11530856
REFERENCE   10 (bases 1 to 4000)
  AUTHORS   Lee,Y.J., Park,C.W., Hahn,Y., Park,J., Lee,J., Yun,J.H., Hyun,B.
            and Chung,J.H.
  TITLE     Mit1/Lb9 and Copg2, new members of mouse imprinted genes closely
            linked to Peg1/Mest(1)
  JOURNAL   FEBS Lett 472 (2-3), 230-234 (2000)
   PUBMED   10788617
  REMARK    GeneRIF: Copg2 gene, closely linked to Mest/Peg1 gene on chr 6, is
            paternally imprinted.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC183098.3 and AEKQ02054615.1.
            
            On Aug 23, 2022 this sequence version replaced NM_017478.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147943.1, BC049178.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            imprinted gene         :: PMID: 10788617, 12879359
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-117               AC183098.3         7546-7662
            118-170             AC183098.3         8729-8781
            171-251             AC183098.3         9396-9476
            252-323             AC183098.3         13651-13722
            324-403             AC183098.3         18664-18743
            404-479             AC183098.3         40713-40788
            480-572             AC183098.3         42863-42955
            573-659             AC183098.3         44349-44435
            660-817             AC183098.3         45428-45585
            818-951             AC183098.3         78052-78185
            952-1019            AC183098.3         78629-78696
            1020-1208           AC183098.3         79767-79955
            1209-1304           AC183098.3         87485-87580
            1305-1548           AC183098.3         88149-88392
            1549-1624           AC183098.3         90537-90612
            1625-1728           AC183098.3         91476-91579
            1729-1854           AC183098.3         92605-92730
            1855-1917           AC183098.3         93336-93398
            1918-2057           AC183098.3         93853-93992
            2058-2229           AC183098.3         94593-94764
            2230-2327           AEKQ02054615.1     6229-6326
            2328-2466           AEKQ02054615.1     6965-7103
            2467-2565           AEKQ02054615.1     7360-7458
            2566-4000           AEKQ02054615.1     7877-9311
FEATURES             Location/Qualifiers
     source          1..4000
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 12.54 cM"
     gene            1..4000
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /note="coatomer protein complex, subunit gamma 2"
                     /db_xref="GeneID:54160"
                     /db_xref="MGI:MGI:1858683"
     exon            1..117
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..2696
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coatomer subunit gamma-2; gamma-2-coat protein"
                     /codon_start=1
                     /product="coatomer subunit gamma-2 isoform 1"
                     /protein_id="NP_059506.1"
                     /db_xref="CCDS:CCDS85027.1"
                     /db_xref="GeneID:54160"
                     /db_xref="MGI:MGI:1858683"
                     /translation="MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRC
                     LHILTKILYLLNQGEHFGTMEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDV
                     IIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAVERYMKQAIVDKVSSVASSAL
                     VSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKF
                     TKSGLKSQFAYCMLIRIASRLLKESEDGHESPLFDFIESCLRNKHEMVIYEAASAIIH
                     LPNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLIT
                     DSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCHKYPR
                     KHSVMMTFLSNMLRDDGGFEYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTV
                     LATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQNESLLPS
                     ILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMALNATYIFNGLTVSIPGMEKALHQYT
                     LEPSEKPFDMKSIPLAMAPVFEQKSEITLVTPKPEKLAPSRQDIFQEQLAAIPEFMNL
                     GPLFKSSEPVQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLNDQLLEKVTVQMEPSD
                     SYEVLCCIPAPSLPYNQPGICYTLVRLPDEDPTAVAGTFSCTMKFTVRDCDPNTGVPD
                     EDGYDDEYVLEDLEVTVSDHIQKILKPNFAAAWEEVGDAFEKEETFALSSTKTLEEAV
                     NNIITFLGMQPCERSDKVPENKNSHSLYLAGVYRGGYDLLVRSRLALADGVTMQVTVR
                     SKERTPVDVILASVG"
     exon            118..170
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            171..251
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            252..323
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            324..403
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            404..479
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            480..572
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            573..659
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            660..817
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            818..951
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1019
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1208
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1304
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1548
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1624
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            1625..1728
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            1729..1854
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            1855..1917
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            1918..2057
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2229
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            2230..2327
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            2328..2466
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            2467..2565
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     exon            2566..4000
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3122..3127
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /note="hexamer: AATAAA"
     polyA_site      3142
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /note="major polyA site"
     regulatory      3979..3984
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
                     /note="hexamer: AATAAA"
     polyA_site      4000
                     /gene="Copg2"
                     /gene_synonym="gamma-2-COP"
ORIGIN      
        1 cttcctgcag cgtcttccgc tcgccggctg cggcgcctgg gacggttgcg gtgggtctgg
       61 gcgctgggaa gccgtccaag atgattaaaa aattcgacaa gaaggacgag gagtctggta
      121 gtggttccaa tcctttccag catttggaga agagtgctgt cttgcaggag gcacgcatat
      181 tcaacgaaac gcccatcaat ccaagaagat gcttgcatat cttgacaaag attctttact
      241 tactcaacca gggtgaacac ttcggaacta tggaagctac agaagccttc tttgcaatga
      301 ctcgattgtt tcaatctaat gatcaaacgc tgaggcggat gtgctacctc accatcaagg
      361 aaatggccac catctctgag gatgtgatca ttgtcacaag cagtctgacc aaggacatga
      421 ctggaaagga agatgtatac cgaggcccag ccatcagggc tctctgcaga atcacagatg
      481 gaacaatgtt gcaagccgtt gaaaggtaca tgaagcaggc cattgtggat aaagtatcca
      541 gtgtagccag ctcagcgctg gtctcttcct tacacatgat gaagataagc tatgatgtgg
      601 ttaaacgatg gataaatgaa gcccaagaag ctgcatcaag tgacaatatc atggtgcagt
      661 accatgcact aggagtgctc tatcacctta ggaagaatga tcggcttgct gtctccaaga
      721 tgttaaataa gtttaccaaa tctggtctca aatcacagtt tgcatactgt atgctgattc
      781 gaattgctag tcgcttactg aaagaaagcg aggatggtca tgaaagtcca ctctttgatt
      841 tcattgagag ctgcttgcga aataaacacg aaatggttat ttatgaagct gcttctgcca
      901 ttattcatct tcccaactgt actgcaagag agctggcacc tgctgtctca gttcttcaac
      961 ttttctgtag ctctcctaaa ccagccttga gatatgcagc tgtgaggacc ctgaacaagg
     1021 tggcaatgaa gcacccctct gctgttactg cctgcaatct ggacttagaa aacttaatca
     1081 cagactcaaa caggagcatt gctaccctgg ccattacaac attgctcaaa acaggaagcg
     1141 agagcagtgt agacaggctt atgaagcaga tatcttcttt tgtgtctgaa atctcagatg
     1201 agttcaaggt ggtggtcgtg caggccatca gtgctctctg tcacaagtac cctcggaagc
     1261 acagcgtcat gatgactttt ctttccaaca tgcttcgaga tgatggaggt tttgaataca
     1321 aaaaggccat tgtggactgc ataatcagca ttgtggaaga gaaccctgag agtaaagaag
     1381 ctggtctagc ccacctctgt gaattcattg aggactgtga acataccgtt ctggctacta
     1441 aaattctcca cttattgggc aaagagggcc ctagaactcc tgttccctcc aagtatatca
     1501 gattcatttt taatagggtg gtcctggaga atgaggctgt cagagctgct gctgtgagtg
     1561 ctttggctaa atttggggct cagaatgaga gccttctccc cagcatcctt gtactcttac
     1621 aaaggtgtat gatggatact gatgatgagg tacgggaccg agctaccttc tacctgaatg
     1681 tgctacagca gagacagatg gccctgaatg ctacatatat cttcaatggt ctgacagtct
     1741 ctataccagg gatggaaaag gccttacacc agtatacatt ggagccttca gaaaaaccct
     1801 ttgatatgaa gtcaattcct cttgctatgg ctcctgtctt tgagcagaag tcagaaatta
     1861 cacttgtgac tcctaagcca gagaagttgg ctccttccag gcaagacatt ttccaagaac
     1921 agttagctgc cattcctgag tttatgaacc tgggaccctt gtttaagtct tctgagcctg
     1981 tgcagcttac agaagcagag acagagtatt tcgttcgctg tgtgaagcac atgtttactg
     2041 accatattgt attccagttt gactgtacca acactctaaa tgaccagctg ctggagaaag
     2101 taacagtgca gatggaacca tccgattcct atgaagtgct gtgctgtatc ccagctccca
     2161 gcctccctta caatcagcca ggaatatgct acacacttgt tcgattgcca gatgaagatc
     2221 ctacagcagt tgcaggcacc tttagctgta ccatgaagtt cacagtccgg gattgtgacc
     2281 ctaatactgg agttccagat gaagatggat atgatgatga atatgtgctg gaagatcttg
     2341 aagtaactgt gtctgatcat attcagaaga tactaaaacc taacttcgct gctgcctggg
     2401 aagaggtggg agatgccttt gaaaaagaag aaacctttgc cctgagctct acaaaaaccc
     2461 ttgaagaagc tgtcaacaac atcatcacat ttcttggtat gcagccatgt gagaggtcag
     2521 ataaagtccc cgagaataag aactcccact ccctctatct agcaggtgta tacagaggtg
     2581 gctatgactt attggtgcgg tccaggctgg ccctagctga tggagtgacc atgcaggtga
     2641 ctgtgagaag caaagagaga acgcctgtgg atgttatctt ggcttctgtg ggataagttc
     2701 ttgctgggaa gggtgatgtt gctatgccct ccctattggt ggtttttagg ctagtggcat
     2761 gatcttccaa gaatcacaca taaagattaa taatgatgac tttgaagaag caaatccaag
     2821 tgtttggccc tgcgccagca gatcaaacat ctgtctgtct gtctgtcttt gagcatgagc
     2881 tttagagttt cttccctcat ctcatgtctc actcactcag cctcggtgcg acaatgcagc
     2941 tttgagtggg cttgaaaatc agatactact tatgctattc tacagctgct tagcttcatt
     3001 atatgcttct atttaatgtg tgaaaaactc ttggcaatgc tggaaaattt tatcccagaa
     3061 gggtggaggg ggaggggaag ccggaatcca tttttgtcac agtttgtttt tattaataga
     3121 aaataaacac tcattcattc cagtttcaaa gttgctatac ttgaaatttc taatttaaaa
     3181 aacgaattta aaataatcaa taatgctgct ttaactaagt taaaactgtg gcttaaaaaa
     3241 gtattcagca ccatttgctc ttaggtcttt cagaatttgt tcttaatgtc tctggaaact
     3301 tgcctgttta agtacaggag ttatatgaga aagcctttct gaacagccag cgggatgctg
     3361 agcggccatc atagaggagc caatggacat tcattccgca cttacatgtc ccttcccctc
     3421 cacgtcagcc ctggaggagc tgcccctagg ctgttattta ctattcagct tggactttct
     3481 aaacagtaac agtaaatctc tggcacagat gcagttctta atgcctggca gttttaggaa
     3541 attctgcaaa taatttcaac ctgtttattc acaaattcta tatataatga ggttttcttc
     3601 ttagcaaggg ccaactgttt gtaaatatat acatgagtat gcaaatcagt cttagactca
     3661 tactcagaac actgtattta cgccaatgtc tatttaggtt cgatgggctg gggtggggag
     3721 agtgctggga actgaaccca agggctttaa catgctaggc aggcacacta ccactgagct
     3781 acttccccag ccccctaagc caatgtctgt tttaacaaaa atgtctgtta gaagcagccg
     3841 atgaaactaa atgtaaagga gtgacaagat gatccctctc ataaactgta acagatcctg
     3901 aaagggagat agcaagctcc tccctcactc tgtattccag ttaggattgg gccggaaggg
     3961 agcacttcta aatattttaa taaagtccac agaaactggg
//
