LOCUS       NM_133850               3213 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus COMM domain containing 7 (Commd7), transcript variant
            1, mRNA.
ACCESSION   NM_133850
VERSION     NM_133850.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3213)
  AUTHORS   Ishida,C., Ura,K., Hirao,A., Sasaki,H., Toyoda,A., Sakaki,Y.,
            Niwa,H., Li,E. and Kaneda,Y.
  TITLE     Genomic organization and promoter analysis of the Dnmt3b gene
  JOURNAL   Gene 310, 151-159 (2003)
   PUBMED   12801642
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY295213.1, AK078774.1, BX521840.1 and AV146140.2.
            
            On Sep 3, 2010 this sequence version replaced NM_133850.1.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078774.1, SRR17784648.391382.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                BY295213.1         2-43
            43-2545             AK078774.1         2-2504
            2546-2993           BX521840.1         93-540
            2994-3213           AV146140.2         379-598
FEATURES             Location/Qualifiers
     source          1..3213
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 75.73 cM"
     gene            1..3213
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /note="COMM domain containing 7"
                     /db_xref="GeneID:99311"
                     /db_xref="MGI:MGI:1914197"
     exon            1..188
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..707
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /note="isoform 1 is encoded by transcript variant 1; COMM
                     domain-containing protein 7"
                     /codon_start=1
                     /product="COMM domain-containing protein 7 isoform 1"
                     /protein_id="NP_598611.2"
                     /db_xref="CCDS:CCDS16912.2"
                     /db_xref="GeneID:99311"
                     /db_xref="MGI:MGI:1914197"
                     /translation="MGRLHCTQDPVPEAVRGDMQQLNQLGAQQFSDLTEVLFHFLTEP
                     KEVERFLAQLSEFATSNQISLGPLKSIMKSLLLVPNGALKKGLTAEQVRTDLQTLGLS
                     EEKATYFSEKWKQNASTLAQWAMGQTLMVNQLIDMEWRFGVTSGSSELEKVGSIFLQL
                     KLVVKKGKQTENLYMELTLPQFYSFLHEMERVRASMECLS"
     exon            189..242
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /inference="alignment:Splign:2.1.0"
     exon            243..345
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /inference="alignment:Splign:2.1.0"
     exon            346..402
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /inference="alignment:Splign:2.1.0"
     exon            403..440
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /inference="alignment:Splign:2.1.0"
     exon            441..531
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /inference="alignment:Splign:2.1.0"
     exon            532..581
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /inference="alignment:Splign:2.1.0"
     exon            582..630
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /inference="alignment:Splign:2.1.0"
     exon            631..3213
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1179
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /note="major polyA site"
     regulatory      1294..1299
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /note="hexamer: AAGAAA"
     polyA_site      1317
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /note="major polyA site"
     regulatory      3192..3197
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
                     /note="hexamer: ATTAAA"
     polyA_site      3211
                     /gene="Commd7"
                     /gene_synonym="2310010I22Rik; mU3"
ORIGIN      
        1 gagaaccgcg gctgggagtg tggcgaaagt gcggctgcgg aagcgcagcg agacccgggt
       61 ggaggaagcg agcgtcgctg cccggttgcg gggttcctgg caccatgggc cgcctgcact
      121 gcacgcagga cccggtgccc gaggccgtgc gcggagacat gcagcagctg aaccagctgg
      181 gcgctcagca gttctccgac ctgacagaag tgcttttcca tttcctaact gagcccaaag
      241 aggtggagcg atttctggct cagctctctg aatttgccac cagcaatcag atcagtcttg
      301 gccccctcaa aagcatcatg aaaagcctcc tactggttcc aaatggtgca ctgaagaaag
      361 gcctcactgc cgagcaggtg cggactgatc tccagacgct aggtcttagc gaggagaaag
      421 ccacttactt ttctgaaaag tggaagcaga acgcctcgac ccttgcacag tgggccatgg
      481 gtcagaccct gatggttaac cagctgattg atatggagtg gaggtttgga gtgacgtctg
      541 ggagcagtga attagagaaa gtgggaagca tatttttaca gttaaagttg gtggttaaga
      601 aaggaaaaca aactgaaaat ttgtatatgg aactaacctt gccccagttc tacagcttcc
      661 tgcacgagat ggagagagtc cgagcgagca tggagtgcct cagctgaccc tgttcccgtt
      721 cccttgcccc tgcctcttcc ctagtgtcag cctactccag gctcccagct gccttgagag
      781 gccgcggaca aagagcttct aaaaccaaga gtctcagcgc ttgaggagtg ctgcctgatt
      841 cttctgcaag ccccactggg agccaccacc tccggctcct gggtgacttt acacctagat
      901 gctccgagag ctactgcatc tgggactgtg tcctttctct gggaggcagt cttgtcacct
      961 cccatccaac agttcacaaa cggctcagtt ccttcattca gatggttggg tacgtgcttg
     1021 tggctgagga agggcgggtg gtgtggacag tgtgtcagga gtggtgtcac acgtgtcaca
     1081 ctgtttggag ggggaagggc attgccagcc actgtctgcc gagtcgtctg tgtaaaagcc
     1141 tgtgcttagt cttctctgga aagaactgag gccagacgat ttctgtgttt gtctctttgg
     1201 cttttgtgtt ataaggaggc aggcctttcg aggccatctt acattgtttg gttccagaaa
     1261 accaaccacc ttttggttaa gtggtaaatt aaaaagaaaa acagtttcta aagaaaagct
     1321 ctgaatccac aaaatgtctt tctccatggt ttaagagtca gccgacctgg gtgtagcggc
     1381 atatacctac aaccttggcc ctgcggagac agagacggga agatcaccat aagctagagg
     1441 ttagccagag cagcaaagtg agagcctgtc tcaaaccaag ccagccatgg gggcgagact
     1501 gacggctctg tggttaagag tgcttcctgc tctttgggga gtccctggtt gctctgttca
     1561 cagcatccac ttctggaagc tcacaacagc ctgtaactcc aacctcacat cttcttatcc
     1621 aagagcaggc atacacatgc catgagtata cacatacaca tatacactct gacacacatt
     1681 cattcaataa tgcaaatgaa ataaatcttc tttaaaaggc cacagggggg ctggtgagat
     1741 ggctcagtgg gtaagagcac ccgactgctc ttctgaaggt cccgagttca aatcccagca
     1801 accacatggt ggctcataaa aggccacagg gtgtggcata gctcagttgg gaaagtgttt
     1861 gcctaacatg cataaaacct ggcgtgggtt atgtggcccc ttgtctcaaa agaataaaac
     1921 cagggccagt gagatgactt agcaggtaaa tacacctacc ccgatgcccg agttcaactc
     1981 ccaggatcca cttggtggaa ggagaccact gatccccaca ggtgtagtct aacctgtaca
     2041 cacccgtgca cacccaagca tgcctactaa gtaaagacat caaattaata taaatatctt
     2101 aattttagat ttggttttca tggtacacct ataatagctt acaaccctct gtaagtccag
     2161 cttcagggaa tttaatgcct ctggcctcca tggatacctg cgcaaatgct cataattaaa
     2221 gataataaat ctctagcctg attgcttaaa tattccgtta aaattctctc tttggaccat
     2281 agctaatctc ataagagaac taggggcttt caccaaaaag agaatggtaa cttgttgttt
     2341 gaaaaagaat gtagttaagg catttctgga tggcttggtg ctcactgtat acccagggct
     2401 gtcctcaaac tcatgacaat cctaccttgc cctccaacaa atgagtgctg ggattacagg
     2461 catggactcc acgcctactc tttacaaggg accaaataca gggctttcct gcatgttaag
     2521 caaaacacag ctgtgttccc agcccataaa agttttgttg ttctcacatt tatttatgtg
     2581 gagttggctg agtcatgttt agggccttgt ggattcaaga caaccttcag gatgtgcact
     2641 cttccttcca tccagccgtc cgcagcagga taggtctgag tagacgtgag gaccccttcc
     2701 cacctttttt ttttttaaag atttatttat tattatacat aagtacactg tagctgtttt
     2761 cagacacaca gaagagggcg tcagatctca ttatggatgg ttgtgagcca ccatgtagtt
     2821 gctgggattt gaactcagaa cctttggaag agcagtcagt gctcctacct gctgaaccat
     2881 ctcaccagcc ccccttccca cctttttcta gctattcact ggaggagatc tgctagttca
     2941 ttctgtattc tggagctatt tcttgcattt gaatctatgt gcatatcttc tgtgtgtact
     3001 atctcacaca gacagcagcg tgtataaaca ccaacctgca ccttgttttt tccagttcac
     3061 atggagatct ctctttatca aaagcaagag ccgcctcagc ctttgcttcc cccagtgatt
     3121 gatcggacca gtttcctgct ggtttgatac aaggtctttt tgtaacaccc tggatgctct
     3181 gaaatttgaa gattaaagat cttcaccacc att
//
