LOCUS       NM_001417568            1747 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus COMM domain containing 5 (Commd5), transcript variant
            2, mRNA.
ACCESSION   NM_001417568 XM_036159539
VERSION     NM_001417568.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1747)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   2  (bases 1 to 1747)
  AUTHORS   Solban,N., Dumas,P., Gossard,F., Sun,Y., Pravenec,M., Kren,V.,
            Lewanczuk,R., Hamet,P. and Tremblay,J.
  TITLE     Chromosomal mapping of HCaRG, a novel hypertension-related,
            calcium-regulated gene
  JOURNAL   Folia Biol (Praha) 48 (1), 9-14 (2002)
   PUBMED   11871861
  REMARK    GeneRIF: a suggestive localization of mouse Hcarg based on
            conservation of linkage between human and mouse is on chromosome
            15.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157554.7.
            
            On Mar 6, 2023 this sequence version replaced XM_036159539.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA979820.1, SRR5189679.50801.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                AC157554.7         136985-137059       c
            76-1747             AC157554.7         134977-136648       c
FEATURES             Location/Qualifiers
     source          1..1747
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 36.28 cM"
     gene            1..1747
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /note="COMM domain containing 5"
                     /db_xref="GeneID:66398"
                     /db_xref="MGI:MGI:1913648"
     exon            1..75
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /inference="alignment:Splign:2.1.0"
     exon            76..1747
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..803
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /note="hypertension-related, calcium regulated"
                     /codon_start=1
                     /product="COMM domain-containing protein 5"
                     /protein_id="NP_001404497.1"
                     /db_xref="GeneID:66398"
                     /db_xref="MGI:MGI:1913648"
                     /translation="MSALGAAAPYLHHPTDSHSGRVSFLGSQPSAEVTAVAQLLKDLD
                     RSTFRKLLKLVVGALHGKDCREAVQHLGASANLSEERLAVLLAGTHTLLQQALRLPPA
                     SLKPDAFQDELQELGIPQDMIGDLASLAFGSQRPLLDSVAQQQGSSLPRVSNFRWRVD
                     VAISTSAQSRSLQPSVLMQLKLTDGSAHRFEVPIAKFQELRYSVALVLKEMAELERKC
                     ERKLQD"
     regulatory      1002..1007
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /note="hexamer: ATTAAA"
     polyA_site      1029
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /note="major polyA site"
     regulatory      1049..1054
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /note="hexamer: ATTAAA"
     polyA_site      1073
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
     regulatory      1336..1341
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /note="hexamer: AATACA"
     polyA_site      1363
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
     regulatory      1596..1601
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /note="hexamer: AATAAA"
     polyA_site      1613
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
     regulatory      1729..1734
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
                     /note="hexamer: ATTAAA"
     polyA_site      1747
                     /gene="Commd5"
                     /gene_synonym="2310065H03Rik; D15Ertd81e; Hcarg"
ORIGIN      
        1 aagtttcagc tgctgccagc cacagccagc tcctgcggat agcttcctcc aggtgcagag
       61 ggcgttcaag gcttagctac tgtggttagt accttctctc cggcctggtc aagaaaggga
      121 aaggaaggat gtctgcgttg ggggctgcgg ctccatactt acaccatcca actgacagtc
      181 acagcggccg ggtcagtttc ctgggttccc agccctctgc agaagtgacg gcagtggccc
      241 agctcttgaa ggacttagac aggagcacct tcagaaagtt gttgaaactc gtagtcgggg
      301 ccctccatgg gaaagactgc agagaggccg tgcagcacct tggtgccagc gccaacctgt
      361 cagaggagcg tctggccgtc ctgctggcgg gcacacacac cctgctccag caggctctcc
      421 ggctgccccc tgccagtctg aaaccagatg ccttccagga cgaactccag gaacttggca
      481 ttccccaaga tatgattgga gatctggcca gtttggcatt tgggagtcaa cgccctcttc
      541 tcgactctgt agcccagcag cagggatcct cgctgcctcg tgtgtcgaat ttccggtggc
      601 gggtggatgt ggccatctca accagtgctc agtcccgctc cctgcaaccg agtgttctca
      661 tgcagctgaa gctcacagat ggatcggcac accgcttcga ggtgcccata gccaaattcc
      721 aggagctgcg ctacagcgtg gcgttggtcc ttaaggagat ggcagagctg gagagaaagt
      781 gtgagcgcaa actgcaggac tgaaccctgg tactgtgggg tgctgaagct ggtaccagaa
      841 cccagccgca ctggtgatga ggatgtaaga acatatttta agtgaaaaga cagctgggac
      901 ttttgggttt tgttttacaa gtaaacagct gggctgaggc tggagaatgt gaaatgtaag
      961 gccggcctgg ctgggtttta cgtagtgagg ctcagtttcg aattaaagag gtaaagcaac
     1021 tattaaaaac atgttattct attagggaat taaacctacc tgtcccttcc ccagctgtgc
     1081 tcctggatga gacgatgtgc agagctaagt ccagatgaag atctcttaca acatacaaca
     1141 tggttgctca gcatggctga actctgccca tttgctttcc taagtcctgt gctttgctgc
     1201 ggacgtgttt attcttttgc cctaaattcc tgctttcctg aagctgacat cctagtggaa
     1261 agatcagagg gggtgggggg aagacattac aaatactaaa tatgcattaa ataatgtttg
     1321 gtatatataa cattaaatac atattttaaa tattaagaca tgagaacagg gccggaggat
     1381 tgattgagca gtgaagagca cttgcccttg caaagaggac ttgggttcaa gtcccagcat
     1441 tcacgtggtg gctcacaacc ttctgtaact tcagttgtgg gggaagggca ggggggaccc
     1501 aacaccaaga catccaacac aggcacatat gtggtactca aacatacatg caagcaaact
     1561 actcatactc agaaagttgt aaatctaaaa caaacaataa aactatgagt acagcttgtg
     1621 acaattgaat agagccaggt cagatgagga gaaggttggt cacaggagta ctctgcagac
     1681 ggatcaagtg gtgtgtcggc tgctagtgaa gccatgcagc gttagtggat taaaaccttt
     1741 gaatgtg
//
