LOCUS       NM_175095               2961 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus COMM domain containing 2 (Commd2), mRNA.
ACCESSION   NM_175095
VERSION     NM_175095.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2961)
  AUTHORS   Skarnes,W.C., Rosen,B., West,A.P., Koutsourakis,M., Bushell,W.,
            Iyer,V., Mujica,A.O., Thomas,M., Harrow,J., Cox,T., Jackson,D.,
            Severin,J., Biggs,P., Fu,J., Nefedov,M., de Jong,P.J., Stewart,A.F.
            and Bradley,A.
  TITLE     A conditional knockout resource for the genome-wide study of mouse
            gene function
  JOURNAL   Nature 474 (7351), 337-342 (2011)
   PUBMED   21677750
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK143821.1.
            
            On Apr 5, 2007 this sequence version replaced NM_175095.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143821.1, SRR1660821.69661.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2961              AK143821.1         2-2962
FEATURES             Location/Qualifiers
     source          1..2961
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 27.94 cM"
     gene            1..2961
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /note="COMM domain containing 2"
                     /db_xref="GeneID:52245"
                     /db_xref="MGI:MGI:1098806"
     exon            1..98
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..631
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /codon_start=1
                     /product="COMM domain-containing protein 2"
                     /protein_id="NP_780304.2"
                     /db_xref="CCDS:CCDS17362.1"
                     /db_xref="GeneID:52245"
                     /db_xref="MGI:MGI:1098806"
                     /translation="MLLDLSEEHKEHLAFLPQVDTAVVAEFGRIAVEFLRRGSNPKIY
                     EGAARKLNVSSDTIQHGVEGLTYLLTESSKLMISELDFQDSVFVLGFSEELNKLLLQL
                     YLDNRKEIRTILNELAPRLPSYHSLEWRLDVQLASRSLRQQIKPAVTIKLHLDQNGDH
                     STHFLQTDPATLLHLVQQLEQALEEMKTNHCRRVVRSIK"
     exon            99..176
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /inference="alignment:Splign:2.1.0"
     exon            177..259
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /inference="alignment:Splign:2.1.0"
     exon            260..433
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /inference="alignment:Splign:2.1.0"
     exon            434..2961
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /inference="alignment:Splign:2.1.0"
     regulatory      928..933
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /note="hexamer: AATAAA"
     polyA_site      951
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /note="major polyA site"
     polyA_site      1107
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
     regulatory      2753..2758
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
                     /note="hexamer: AATAAA"
     polyA_site      2781
                     /gene="Commd2"
                     /gene_synonym="1190017G07Rik; D3Ertd176e; HSPC042"
ORIGIN      
        1 gccgggtggc aaagtctgaa gagccgctaa aatgctgctg gatttgtccg aggagcacaa
       61 ggagcacttg gccttcctgc cgcaagtgga cactgcagtg gtcgccgagt tcgggaggat
      121 cgccgtggag ttcctccgac ggggctcaaa cccgaagatc tacgaaggcg ccgccagaaa
      181 actgaacgtg agtagtgaca ctatccagca tggtgtggaa ggattaacgt atctcctcac
      241 cgagagctca aagcttatga tttctgaact ggatttccaa gactctgtct ttgttctggg
      301 attctctgaa gaactaaaca aattattgct tcagctctac ctggacaaca gaaaggagat
      361 cagaactatt ctgaacgagt tagcacctcg tcttcccagt taccatagtc ttgagtggcg
      421 gctagatgta cagcttgcaa gcagaagtct ccggcaacag attaagccag cagtgaccat
      481 aaagctgcac ctcgatcaga atggcgacca cagcactcat ttcttgcaga cagacccagc
      541 taccctgctt catttggttc agcagctgga gcaggcgtta gaggaaatga aaacaaacca
      601 ctgcaggaga gtagtccgca gcatcaagta gctctgaggt ttccttcctt ccagttggag
      661 acactggcgt ggcagtggta cgtctggatt cgtggagttt ctttccctgc tcaggatgtt
      721 gaaatcttga tcagaagctg agccgcagct ccgttttggt gctgaatgcg gtcagcttct
      781 tgcaggttgg aaagcatttt ttacttcaag tgtgtaaaga ggatgcacca actaagatgg
      841 atcaatactg ctgatttctg tggactcttc ggacttggat atttttttta tctactttat
      901 ttcctttgct cttgatcaaa atttgaaaat aaaattcact gttactactt agaactattt
      961 ctagacagtt caatattttt ttcttctaaa agcactatac aattacagcc atagaaaaag
     1021 acaaatagga tttctacaag cttttctata ttgttacagg tagcatgtgt attcttgttt
     1081 gtatgtaaag atgataagta tcatttacca tattgcttac atttgagtta ttggggctaa
     1141 ttaatttaag tgatatacaa gtttgtgtgg tctaatgtac attttatcag ggactaactt
     1201 cccccattcc caaagcaact aaaagacaca ccatcactta gatttacaaa caatgatgta
     1261 aaagtagaat gatcaattct tttttatctt tacatattta ttttgtgtgg gtgggtgttt
     1321 tgcctacatg tatgtctgtg caccttgtgt gttcgtgcac acagtggcca gaaaagggta
     1381 ttggatccct tggagctaga cttacaaagg ggtgtaagct tccactgggt gctgaggctc
     1441 aaacccagct catctagaag agcagtcagt gctcttaacc accaaaccat ctctccagcc
     1501 ccaaaatagg tttttgtttt tttgttttgg tttgctttat gttttaatat ttactttatt
     1561 tgtgtgtgtt ttcatccaaa ggctaaagtt agggagttag ttctctcttc ctatcctatg
     1621 ggtcctggag atagaactca ggtcatctgg catattgaca aaaacgttta cccactagtt
     1681 gtcttagatg tatagacata attttaatta cactgagggc taagttaatg aaactgccac
     1741 attaaaaaac ccacaaggaa ggaaaccatg agttagcagt gcatgtcacg gggtttaaag
     1801 gtagcctccc tgccaagctg ttacagctct gggaggctta cttgtccaca gcggacagac
     1861 gatgaactag gtttccccac tcccaatatt gaatgattag cctgtgtcct tctaagcaac
     1921 ctttcttcca ccccttggtt cattgtctta gctcaatcaa aagatgaaag cagttagcat
     1981 agtggtacat gactagttct agtgcctagg agacagagct ctgtgattcc aaggcagctt
     2041 gctctacaga acattctagg ccagctaggg ccacatgaag agactcggtc tacacacaca
     2101 caccaagata aaagcatatg ctatttgaaa aaggaaaaaa acaaaaacaa aaacagttct
     2161 cccaactgtt ctcatattga ttatttctgt ggtgatgggc cctttggggg caaagaaaga
     2221 ttgtgagtaa tccccctgcc cctccctcca acacctttta gaccttaaac accatcaggt
     2281 aagcatattc ctttttgttg ttgttgtttt tctcagacat tgttttatga cacattgggt
     2341 aattttcaat tcttaattgc tttttaaaaa taaattagcc tgtaaattaa agggtttcat
     2401 gatgaaaccc cttatatgtt ttcatacata tacatcattg tactgtcttt gtactgtttg
     2461 atccttcccc gccttactag ccccccaccc accccgaccc cacttcctct tgctggtcac
     2521 catccctgag tcacccctct gctttcatgt cataagtatt ccatcatctt ttctttgttc
     2581 cccttctgta agctctctta ggatccacat atagaagaaa cacattaatt taaatctaga
     2641 ttctgcatag taaaagtatg gtatttgtct atatttttct gtttaacata atgatctaca
     2701 gttgtatcta ttttcctaca aatgtcacaa tttcagtttt tctgtatagc tgaataaaat
     2761 tccattgcat tggggcttgt agagatggct cagcagttat gagcactagt acctcttgaa
     2821 gaagatctga gttcagttcc ccagttcccg gcacccacat ggcagatcac aactgtctat
     2881 gtaaactcta gttccaggga tctgacaccc ttttctggct tccttgtggt gtacaaacat
     2941 gcacataagc aaaacaccta t
//
