LOCUS       NM_177756               4080 bp    mRNA    linear   ROD 17-DEC-2022
DEFINITION  Mus musculus collagen beta(1-O)galactosyltransferase 2 (Colgalt2),
            mRNA.
ACCESSION   NM_177756
VERSION     NM_177756.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4080)
  AUTHORS   Yang J, He L, Gao M, Xiao F, Zhang F, Wang S, Shu Y, Ye X, Qu W, Li
            L and Wei H.
  TITLE     Collagen beta(1-O) galactosyltransferase 2 deficiency contributes
            to lipodystrophy and aggravates NAFLD related to HMW adiponectin in
            mice
  JOURNAL   Metabolism 120, 154777 (2021)
   PUBMED   33865898
REFERENCE   2  (bases 1 to 4080)
  AUTHORS   Zhang X, Guo L, Zhang X, Xu L, Tian Y, Fan Z, Wei H, Zhang J and
            Ren F.
  TITLE     GLT25D2 Is Critical for Inflammatory Immune Response to Promote
            Acetaminophen-Induced Hepatotoxicity by Autophagy Pathway
  JOURNAL   Front Pharmacol 11, 01187 (2020)
   PUBMED   33071774
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4080)
  AUTHORS   Hao X, Liu R, Zhang Y, Li Y, He Q, Huang Y, Jiang Y, Ma J, Li P and
            Wei H.
  TITLE     Glt25d2 Knockout Directly Increases CD25+CD69- but Decreases
            CD25-CD69+ Subset Proliferation and is Involved in
            Concanavalin-Induced Hepatitis
  JOURNAL   Cell Physiol Biochem 50 (3), 1186-1200 (2018)
   PUBMED   30355948
REFERENCE   4  (bases 1 to 4080)
  AUTHORS   Tao G, Levay AK, Peacock JD, Huk DJ, Both SN, Purcell NH, Pinto JR,
            Galantowicz ML, Koch M, Lucchesi PA, Birk DE and Lincoln J.
  TITLE     Collagen XIV is important for growth and structural integrity of
            the myocardium
  JOURNAL   J Mol Cell Cardiol 53 (5), 626-638 (2012)
   PUBMED   22906538
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK052838.1 and BC068118.1.
            
            [WARNING] On May 10, 2023 this sequence was replaced by
            NM_177756.5.
            
            On Apr 29, 2009 this sequence version replaced NM_177756.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC068118.1, AK134084.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                AK052838.1         2-55
            55-2116             BC068118.1         1-2062
            2117-3127           AK052838.1         2118-3128
            3128-4080           BC068118.1         3074-4026
FEATURES             Location/Qualifiers
     source          1..4080
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1"
     gene            1..4080
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /note="collagen beta(1-O)galactosyltransferase 2"
                     /db_xref="GeneID:269132"
                     /db_xref="MGI:MGI:2138232"
     exon            1..531
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     CDS             272..2149
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /EC_number="2.4.1.50"
                     /note="procollagen galactosyltransferase 2; hydroxylysine
                     galactosyltransferase 2; glycosyltransferase 25 family
                     member 2; glycosyltransferase 25 domain containing 2"
                     /codon_start=1
                     /product="procollagen galactosyltransferase 2 precursor"
                     /protein_id="NP_808424.3"
                     /db_xref="CCDS:CCDS15364.1"
                     /db_xref="GeneID:269132"
                     /db_xref="MGI:MGI:2138232"
                     /translation="MAARLATVACALFLLSSALLRLGCRARFAAEPDSDEDGEETVAF
                     PESPPQKPTVFVVVLARNAAHTLPYFLGCLERLDYPKSRMAIWAATDHNVDNTTEILR
                     EWLKSVQRLYHYVEWRPMNEPESYPDEIGPKHWPNSRFSHVMKLRQAALRTAREKWSD
                     YILFIDVDNFLTNPQTLNLMIVENKTIVAPMLESRGLYSNFWCGITPQGFYKRTPDYL
                     QIREWKRMGCFPVPMVHSTFLIDLRKEASDKLAFYPPHQDYTWTFDDIIVFAFSSRQA
                     GIQMYLCNKEHYGYLPIPLKPHQTLQEDVENLIHVQIEAMIDHPPMEPSQFVSVVPKY
                     PDKMGFDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTSQLKAWNIEM
                     LPGYRDPYSSRPLTRGEIGCFLSHFSVWKEVIDRELEKTLVIEDDVRFEHQFKRKLMK
                     LMEDIDKAQLDWELIYIGRKRMQVKEPEKAVPNVVNLVEADYSYWTLGYAISLEGAQK
                     LVGADPFGKMLPVDEFLPIMYNKHPVAEYKEYYESRDLKAFSAEPLLIYPTHYTGQPG
                     YLSDTETSTIWDNETVATDWDRTHSWKSRKQGHIRSTAKNTEALPPPTSLDTVPSRDE
                     L"
     exon            532..642
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            643..760
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            761..895
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1100
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1220
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1297
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1404
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1405..1537
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1665
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1872
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1873..4056
                     /gene="Colgalt2"
                     /gene_synonym="D730024P12; Glt25d2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agacctcagc tgtacaagcg cagcctggac taggggaact ttccctggaa ctcgggaaga
       61 tcagcctccc ggagtcgacc tgtctgcagg gcggagcgcg gggcaagcgc gggtggcagg
      121 gagtcggtgc acaggggact caggtcaagg ctggtcggcg gcgggtcctg cgagcctcag
      181 aaatcagtgc cggtgcacgc tcccgccgtc ccggggcagc cgcatccccg gcgccgctgg
      241 cagcatcgcc gcctcccgcc ggctacggaa catggctgcg cgcctcgcca ctgtcgcctg
      301 cgcgctgttc ctgctgtcct ccgccctgct ccgcctcggc tgccgggcgc gcttcgccgc
      361 cgagcccgac tcggatgagg acggagagga aacggtggcg ttccccgagt cgcccccgca
      421 gaaacccacg gtgttcgtgg tcgttctcgc ccgcaacgct gcgcatacgc tgccttactt
      481 cctcggctgc ctggaacggc tggactaccc caagagcagg atggctatct gggcagccac
      541 tgatcacaat gtggacaata caacggaaat actcagggag tggctgaaaa gtgtgcagcg
      601 tttgtatcac tatgtggagt ggaggcctat gaacgagcca gagtcttacc ctgatgaaat
      661 cggaccaaag cactggccaa actcccggtt ttctcacgtc atgaaactgc gacaagcagc
      721 ccttcgaact gcgagggaaa aatggtcaga ttacatcctg ttcatagatg tcgacaactt
      781 cctgactaat ccacagaccc tgaacctaat gattgtagaa aacaagacca tcgtggcgcc
      841 catgctggag tcccggggtc tatactctaa cttctggtgc ggaattacgc ctcagggctt
      901 ctacaagcgg accccagact accttcagat tagagaatgg aaaaggatgg gctgcttccc
      961 cgtccccatg gtccactcca ccttcctgat tgacctcagg aaagaggcct ctgacaagct
     1021 ggctttctac cccccacacc aggactacac ctggaccttt gatgacatca tcgtttttgc
     1081 cttctccagc aggcaagcag gcatccagat gtacctgtgc aacaaggaac actatggcta
     1141 cctgcccatc cctctgaagc cccaccagac actgcaggag gacgtcgaga acctcatcca
     1201 tgtacagata gaagcaatga ttgaccatcc tccaatggag ccttcccagt tcgtgtcagt
     1261 tgtccctaag tatccagaca agatgggatt tgatgagatt ttcatgatca acctcaaacg
     1321 caggaaggac aggcgggaca ggatgctgcg cacactctac gaacaggaga tcgaggtcaa
     1381 gattgtcgag gccgtggatg ggaaggcact caacacaagc cagctgaagg cctggaacat
     1441 tgagatgctg ccagggtacc gggaccccta ctcctccagg cctttaacca ggggtgaaat
     1501 tggttgcttc cttagtcact tctctgtctg gaaagaggtt attgaccgag agctggagaa
     1561 gactctggtc atcgaggatg atgtgcgctt tgagcatcag tttaagagga agctgatgaa
     1621 gctgatggag gacattgaca aggctcagct ggactgggaa ctaatttaca tcggtcgaaa
     1681 aagaatgcaa gtcaaagagc cagagaaggc agtgcccaat gttgtaaatc tcgtcgaagc
     1741 tgattattcc tactggaccc tgggctacgc catttccctg gaaggagcac agaagcttgt
     1801 cggagccgat ccctttggga agatgttgcc agtggatgag tttctgccaa tcatgtacaa
     1861 caagcatcct gtggctgagt acaaggagta ttatgagtcc agggacttga aagccttctc
     1921 cgcagagcct ctgctcatct accctacgca ctacacaggc cagccaggct atctgagcga
     1981 cacagaaacg tcaaccatct gggacaatga gacagtggcc actgactggg acaggacaca
     2041 ctcctggaaa tcccggaagc aaggacacat ccgcagcacc gccaagaaca cggaagcact
     2101 tccaccgcca acttccctgg acactgtgcc ttcaagagac gaactctgaa agcttcctgg
     2161 gtgtgtggtc tgcaaggttc atcactgtct ggattttcta aagggctact catctgtttg
     2221 ctccagtttg gggttttgtt ttgtagagat ggcagtcatc taatcaagtg gtttgatgtg
     2281 actcatcaaa attatatcat ttgtatagtg aagaacagag aaattaaaaa ccaaattccc
     2341 taggaagcca ttactggaat atctaggtta aacttcagtc caaatgccca gttctgctca
     2401 ctagctagag aatgcggtta gccacactgg tgtggcaaca tggctcatat tctcatccaa
     2461 gaaatggcac cccaagctgt cacatcagta agtgagcagt caacacagac aagccagtgg
     2521 accttgttta ctaatctaag tggtccattt tatgtggcag atgtgaccct gaaatcatca
     2581 agccatctag actacattta ttcatctaat tgatgtgacc ttgaaaactg tactatgtaa
     2641 caagtgtctg ggaatgggga aaccaaacca ttaattgggc ttttattcaa aggagctctg
     2701 tcatgagttt gttgcaaagt ggatgttttc ttcttggctt tattatccca tggagtgaga
     2761 gctggagcga tggctcagtg gttattatcc aatggagtac gtaactggct tgggtagcga
     2821 catgggctct tgaccatcat ggcagctaga gtgttcatca aaatgtctag gtgccatgtg
     2881 gctataatat ttagatattt atgggggaaa gatctaaacc cttggcattt gtattgtggc
     2941 ttaagtccaa tatgtctatt tataaaaaac tgtaatatat acaggttgtg agggatgggg
     3001 tgacccagaa cctcacacct tatatgtcac cccttcgcct ggggaggaac tgcaggtgtg
     3061 agtgtaataa gtcactgttg atgagtttaa taagtcactg ttgagggtca gaatacattt
     3121 cagcctcaca cttgtcctcg ttttggattt tcattatatt ctgaattatt tattttacca
     3181 aagtggaaaa accatcgtct gtagggtgaa gcaagcagag gaacagatgt ctcagactct
     3241 cactgcacac tgggcaatgt cagtattgac acgtgagtct gcgcatctga attgcctgaa
     3301 tttcccagct tggcttttgc agggaagacc gctggtgaga agctaaccag ttaggagtaa
     3361 cttattctcc agtggatata taagacactg gcctagacaa tagatttaag tcaacgatcc
     3421 acagctctca gagccaaaaa tcctaattag acacctttct ccaaaaaagt cccctaaaac
     3481 tttttcctaa ttcttcatag gtaatttaat gtcaggtgca atgctggact gtgtcacaca
     3541 cagtgtcagg attcccagcc agctgttgag agtgcttgtg gtgcttcacc tcagccaccc
     3601 ttccttcctg ggtatgattc aggcttcttg actgaagctg agaaaccagg cttatccagc
     3661 cccagcttgt gtcttctcat ctagagaaaa agagaagagc attaaggagc tcatgaggaa
     3721 ccctaagtgg ttcctaaggt ctccttgggt gttcggtatt ttgtttgtga tttgaatgtg
     3781 tgcaagaatg cctggcttta actgtgtatt ttataggagt gggaggtggc tggggcactg
     3841 gaagtgaagg gagactgagt tatgttttgt gttgttgttg tttttgttgt tttcgtttct
     3901 gttgctgtct taatgggtaa ctttctcccg tttgccctgt cagctggtct gacggattta
     3961 agaattttca ttcttaaaag acattggatt tcaaagtttg aattctagat taggaccttt
     4021 tctaactgtg aataaagttc tggttctgtt agtctaaaaa aaaaaaaaaa aaaaaaaaaa
//
