LOCUS       NM_173422               4587 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus collectin sub-family member 10 (Colec10), mRNA.
ACCESSION   NM_173422
VERSION     NM_173422.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4587)
  AUTHORS   Zhang,M., Jing,Y., Xu,W., Shi,X., Zhang,W., Chen,P., Cao,X.,
            Han,X., Duan,X. and Ren,J.
  TITLE     The C-type lectin COLEC10 is predominantly produced by hepatic
            stellate cells and involved in the pathogenesis of liver fibrosis
  JOURNAL   Cell Death Dis 14 (11), 785 (2023)
   PUBMED   38036508
  REMARK    GeneRIF: The C-type lectin COLEC10 is predominantly produced by
            hepatic stellate cells and involved in the pathogenesis of liver
            fibrosis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4587)
  AUTHORS   Qu,F., Li,W., Xu,J., Zhang,R., Ke,J., Ren,X., Meng,X., Qin,L.,
            Zhang,J., Lu,F., Zhou,X., Luo,X., Zhang,Z., Wang,M., Wu,G., Pei,D.,
            Chen,J., Cui,G., Suo,S. and Peng,G.
  TITLE     Three-dimensional molecular architecture of mouse organogenesis
  JOURNAL   Nat Commun 14 (1), 4599 (2023)
   PUBMED   37524711
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4587)
  AUTHORS   Axelgaard,E., Jensen,L., Dyrlund,T.F., Nielsen,H.J., Enghild,J.J.,
            Thiel,S. and Jensenius,J.C.
  TITLE     Investigations on collectin liver 1
  JOURNAL   J Biol Chem 288 (32), 23407-23420 (2013)
   PUBMED   23814060
  REMARK    GeneRIF: During acute-phase responses, the CL-L1 levels display
            only minor variations. In serum, CL-L1 was found in complexes with
            mannan-binding lectin-associated serine proteases, suggesting a
            role in the lectin pathway of complement activation.
REFERENCE   5  (bases 1 to 4587)
  AUTHORS   Kawai,T., Suzuki,Y., Eda,S., Kase,T., Ohtani,K., Sakai,Y.,
            Keshi,H., Fukuoh,A., Sakamoto,T., Nozaki,M., Copeland,N.G.,
            Jenkins,N.A. and Wakamiya,N.
  TITLE     Molecular cloning of mouse collectin liver 1
  JOURNAL   Biosci Biotechnol Biochem 66 (10), 2134-2145 (2002)
   PUBMED   12450124
  REMARK    GeneRIF: mouse collectin liver 1 gene, Cll1 was found on chromosome
            15 in a region syntenic with human chromosome 8q
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC108945.1 and AK028423.1.
            
            On Apr 1, 2009 this sequence version replaced NM_173422.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028423.1, BC106836.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                BC108945.1         3-55
            54-4206             AK028423.1         56-4208
            4207-4587           AK028423.1         4210-4590
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 21.15 cM"
     gene            1..4587
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
                     /note="collectin sub-family member 10"
                     /db_xref="GeneID:239447"
                     /db_xref="MGI:MGI:3606482"
     exon            1..152
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
                     /inference="alignment:Splign:2.1.0"
     CDS             5..838
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
                     /note="collectin liver 1; collectin-10; collectin-L1;
                     collectin liver protein 1"
                     /codon_start=1
                     /product="collectin-10 precursor"
                     /protein_id="NP_775598.2"
                     /db_xref="CCDS:CCDS27469.1"
                     /db_xref="GeneID:239447"
                     /db_xref="MGI:MGI:3606482"
                     /translation="MNGFRVLLRSNLSMLLLLALLHFQSLGLDVDSRSAAEVCATHTI
                     SPGPKGDDGERGDTGEEGKDGKVGRQGPKGVKGELGDMGAQGNIGKSGPIGKKGDKGE
                     KGLLGIPGEKGKAGTICDCGRYRKVVGQLDISVARLKTSMKFIKNVIAGIRETEEKFY
                     YIVQEEKNYRESLTHCRIRGGMLAMPKDEVVNTLIADYVAKSGFFRVFIGVNDLEREG
                     QYVFTDNTPLQNYSNWKEEEPSDPSGHEDCVEMLSSGRWNDTECHLTMYFVCEFVKKK
                     K"
     exon            153..224
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            225..296
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            297..350
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            351..446
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            447..4587
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4179..4184
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
                     /note="hexamer: AATAAA"
     polyA_site      4199
                     /gene="Colec10"
                     /gene_synonym="CL-L1"
ORIGIN      
        1 agtcatgaat ggctttagag tcctgcttcg aagcaaccta tccatgctgt tgctgctagc
       61 tctcttgcac tttcagagtc tgggtctgga tgttgatagt cgatcagctg cagaagtctg
      121 tgccacacat accatttcac caggacctaa aggggatgat ggtgaaagag gtgacacagg
      181 agaagaaggc aaggatggca aagtgggacg ccagggacca aaaggagtga aaggagagct
      241 gggtgatatg ggagcccagg gtaatattgg caagtctggc cctattggca agaagggtga
      301 caaaggggaa aagggtctgc ttggaattcc tggagaaaaa ggcaaagcag gtaccatctg
      361 tgattgtggc aggtaccgga aagtggttgg acaactggat attagtgttg ctcgtcttaa
      421 gacatcaatg aaattcatca agaatgttat agcagggatc cgggaaactg aagagaaatt
      481 ctactacatt gtgcaggagg agaagaacta cagggaatct ctgacccact gcaggatccg
      541 aggagggatg ctagccatgc ccaaggatga agtcgttaac acccttattg ctgactatgt
      601 cgccaagagt ggtttcttca gagtgttcat tggggtcaat gaccttgaga gggaggggca
      661 atatgtgttc acagataaca ctccattgca gaactacagc aactggaagg aggaggaacc
      721 tagtgacccc tccggccatg aggactgtgt ggagatgttg agctctggca ggtggaatga
      781 cacagagtgt caccttacca tgtattttgt ctgtgagttt gtcaagaaga aaaaataatt
      841 ttcctcatgt tacacagtca ccctttccct gggtctccta gtagtcactt ttatccatct
      901 ttgccttcct aattacattg cttttgctca aatgccataa gggctctgac ccccactatc
      961 ttcttctgtg ttaattgtaa cagttttgta catgctgttt acttggaaca ctcttggaga
     1021 cctttctctt gcttctctat ttaaccctct ggcataatgg aaggaagaca ctagcactca
     1081 gaaggggaag ggagaggtag ttctgaaacg atacaagtta tagataggcc ttctgttaaa
     1141 ttgtcccctg ctattaatga ctccatttta tttcatgaac gtgttcctgt gacattcttc
     1201 accttcaaca taaataatca agagtgaagg gttcaagcct tcagaaaact ctaaaagtgc
     1261 taaagtgcta ctctctctag cactttagca cttttagagt cccccccttc cagctaatac
     1321 atcactcatg gagaaatttt atgggaggcc tttcactctc tgtaaattaa tgttgatgga
     1381 gacacccttt ctattatttt gacaccacag agatatgtcc ggcacagcat ttggaatgtg
     1441 ctgagagtcc tcattgactg agttggcaac agtttacctt gagttgcaga tcaaacctca
     1501 aagcagcttt aatctggcat ttgaaaataa acagtcgaac aaaattctag cttctctcct
     1561 tagaaacgga tgccctgctt atgggttgtg acacatgatt agattgttta aaatgctggc
     1621 aaaacagtta atgaaacaag agaaagagat caacaacata tgttcttctt aaaccatctg
     1681 tttatgactt tgcccatgac taactggtgg tgagaagaga ttactggcac tgactatgtg
     1741 aattcaccaa gactcacaag tccacgtcct acagaatcca gaaagatgac atagatgaac
     1801 tgggaggggt gaggtcccta attcactagt cacagtctgc tctttgaagg aaccaactac
     1861 tttgctgctg ctgttgatgc caccaaaaac ccagaaccac tgcatttgaa ctgaagtcaa
     1921 atggcgggaa cattataatt ccatatttcc aagtgttgac aattaatcaa tatctaacct
     1981 agactctaag acctacaaat gtctgttaac caaattatga actttccatt tccacctctg
     2041 gggaaagttc tgaaagttct aattgtgcca agtgtcatta ggaaatgatg acttcaacat
     2101 caggtctccc atgaatgagt tgttcagttc agctcaatag gagacatttg ttaaatcttt
     2161 gacatttatc aggttattaa agtagttaca gagtctcttt agagaatgtg gcatagggta
     2221 ttttgaaggc cgatcagttt aatataatta caaatcaagg catcacgcca aataccagcc
     2281 aaaatctcag agaattggaa cactcagaaa catgtggagg aaaagaaaag gctgaaagaa
     2341 gagagaggca gccaagagca aacccagcct agggcggctc ctgttggatt catgtttaca
     2401 attgctctga gtccctgaag tctgaatatt ttgaacatat ggcaaatgct atcatttcca
     2461 ttataaattt ataatgttaa cagtcattcg ctcagtaact catctcagtt tggaagacac
     2521 ttctcagagt agatgacagt ttcaaggaat aagatctatc catttctgcc tggaagaact
     2581 tcttaagaca ttgcatcaga actctatgaa aatgaatacc tttttctatt tgttttccaa
     2641 gtgagagtgt cattatatag cccaggctgt ccttgaactc gaaatcttct tgccttatcc
     2701 tcttggatgc tgggtgacag ctatgcaatt ccgagcccag ctgaaaatat accattcaac
     2761 gtgttctctt ttaggaaaag ctctacacct ccttgctcaa ggcagggatg tttactgcca
     2821 ttttccagtg aaaacactgc agctgtaaga aacaaagata ttaacaaatt ggtgatttgg
     2881 aagaaaagca agttcctatc ctggtataag ctgaaagttc cctggaatgc atatttagaa
     2941 ggtagcaagg tctatgtgct ggagtgtggg gagttgagaa atgaagtgaa cagaatccct
     3001 gtaggcactg cctacagagg ctgagatttg taggggttat cgctgatgag aaggttggtg
     3061 gtgtgggttc attcagggtg atacgcctgt atcagcactg agcaaaagtt caaactctag
     3121 atctggccat cacagctgcc tgaatgtcat tgctgactgt gactcttcct agccatgcta
     3181 gccatgttct agggctaatt taaatgtcct ttaccttatc attttctctt catagagaac
     3241 cctgacagct aaggaggagt tagagtgagg tatttggaag aatatcaact agacaaggat
     3301 atgagtgcca caagactcag acattactac taactacatg caccatgggt atgtgagaga
     3361 aacaaagaaa attttgagat atataaaata ttttgatata tatttactta agtaaatata
     3421 aatgtacatc agtatatcat aaatggaaac cctatattta attacataaa atatgagttc
     3481 tagaatacaa aagtaacatc acaggcatct ggagggatat ctcagtggcc aacagcccat
     3541 ggggactcca gttaagttcc agaatccaca ttatgtagtt gacacttgtt tgtaattcca
     3601 acttcaaggg atctaacacc tgaggtggaa gtttctggtt tctttaaaaa tcacaattat
     3661 gtcatgtaat gtttcctgga agctgtttag tgaaagggca tatgatgttt tgctgaaaac
     3721 agacacctca gagggcacgt gatgtttaga aagcatataa atgaatcctc acaagcagtg
     3781 aagagttgct ctcgcattgc aacattgtgc catgctctgc tggtctttgc tggctgtgta
     3841 acacttttct agttttggct ggtctttgtt tcttgacttt gtagaataaa acaagccaaa
     3901 gaccttctca tggtattcca gatgattctg gccatttatt gtgacttgtg gcaatccagc
     3961 ccagccttga agtttctgct ggagcatgct actactagta attcatgttt gatgtatgtt
     4021 attagacggg actgctggta tactgacaac gaagagtgga atcaccctaa agaactactt
     4081 ctaaacaggt ccccaacccc tttttcctat taaccatctt tctcctctac ctcttgttca
     4141 gggggctaga atgaagatgg acacatttaa gaaccctaaa taaagtagat tttgatgaat
     4201 ctgagcctac agaaactatt atctggactc catgggcacc taccctccca tgtgcacagt
     4261 tttacacata aatacacata tatgcacata actgtagaag taaaacaaat ctttttttaa
     4321 aaaaatagaa gttttagtta tgctgctttt agaatatcag gccttcaaac tacagctgaa
     4381 tcctttcatg tatgagggaa aatatctcat atcaataggg actgaagact atgttccatt
     4441 gatcttttat acataaacct ttatatagta tagggatgtg tttcacggtg attctagcag
     4501 atgctcattc agtctgtatt tgtatgcttt gggtaattta ataagccatt gtgataaaat
     4561 aaaatacatt tcatctaatt tgcactc
//
