LOCUS       NM_026763               7388 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus collagen, type VI, alpha 4 (Col6a4), mRNA.
ACCESSION   NM_026763 XM_135159 XM_356184 XM_909190 XM_909209 XM_974255
            XM_974301 XM_979488
VERSION     NM_026763.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7388)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7388)
  AUTHORS   Qiu,C., Martin,B.K., Welsh,I.C., Daza,R.M., Le,T.M., Huang,X.,
            Nichols,E.K., Taylor,M.L., Fulton,O., O'Day,D.R., Gomes,A.R.,
            Ilcisin,S., Srivatsan,S., Deng,X., Disteche,C.M., Noble,W.S.,
            Hamazaki,N., Moens,C.B., Kimelman,D., Cao,J., Schier,A.F.,
            Spielmann,M., Murray,S.A., Trapnell,C. and Shendure,J.
  TITLE     A single-cell time-lapse of mouse prenatal development from
            gastrula to birth
  JOURNAL   Nature 626 (8001), 1084-1093 (2024)
   PUBMED   38355799
REFERENCE   3  (bases 1 to 7388)
  AUTHORS   Qu,F., Li,W., Xu,J., Zhang,R., Ke,J., Ren,X., Meng,X., Qin,L.,
            Zhang,J., Lu,F., Zhou,X., Luo,X., Zhang,Z., Wang,M., Wu,G., Pei,D.,
            Chen,J., Cui,G., Suo,S. and Peng,G.
  TITLE     Three-dimensional molecular architecture of mouse organogenesis
  JOURNAL   Nat Commun 14 (1), 4599 (2023)
   PUBMED   37524711
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7388)
  AUTHORS   Nishida,S., Yoshizaki,H., Yasui,Y., Kuwahara,T., Kiyokawa,E. and
            Kohno,M.
  TITLE     Collagen VI suppresses fibronectin-induced enteric neural crest
            cell migration by downregulation of focal adhesion proteins
  JOURNAL   Biochem Biophys Res Commun 495 (1), 1461-1467 (2018)
   PUBMED   29196262
REFERENCE   5  (bases 1 to 7388)
  AUTHORS   Soret,R., Mennetrey,M., Bergeron,K.F., Dariel,A., Neunlist,M.,
            Grunder,F., Faure,C., Silversides,D.W. and Pilon,N.
  CONSRTM   Ente-Hirsch Study Group
  TITLE     A collagen VI-dependent pathogenic mechanism for Hirschsprung's
            disease
  JOURNAL   J Clin Invest 125 (12), 4483-4496 (2015)
   PUBMED   26571399
REFERENCE   6  (bases 1 to 7388)
  AUTHORS   Boyle,M.P., Bernard,A., Thompson,C.L., Ng,L., Boe,A., Mortrud,M.,
            Hawrylycz,M.J., Jones,A.R., Hevner,R.F. and Lein,E.S.
  TITLE     Cell-type-specific consequences of Reelin deficiency in the mouse
            neocortex, hippocampus, and amygdala
  JOURNAL   J Comp Neurol 519 (11), 2061-2089 (2011)
   PUBMED   21491433
REFERENCE   7  (bases 1 to 7388)
  AUTHORS   Gara,S.K., Grumati,P., Squarzoni,S., Sabatelli,P., Urciuolo,A.,
            Bonaldo,P., Paulsson,M. and Wagener,R.
  TITLE     Differential and restricted expression of novel collagen VI chains
            in mouse
  JOURNAL   Matrix Biol 30 (4), 248-257 (2011)
   PUBMED   21477648
  REMARK    GeneRIF: The collagen VI alpha 4 chain is strongly expressed in the
            intestinal smooth muscle, surrounding the follicles in ovary, and
            in testis
REFERENCE   8  (bases 1 to 7388)
  AUTHORS   Nakajima,M., Miyamoto,Y. and Ikegawa,S.
  TITLE     Cloning and characterization of the osteoarthritis-associated gene
            DVWA
  JOURNAL   J Bone Miner Metab 29 (3), 300-308 (2011)
   PUBMED   21057832
  REMARK    GeneRIF: DVWA is evolutionally very unique, which, together with
            its specific expression in articular cartilage, suggests its
            specific role in human cartilage metabolism.
REFERENCE   9  (bases 1 to 7388)
  AUTHORS   Fitzgerald,J., Rich,C., Zhou,F.H. and Hansen,U.
  TITLE     Three novel collagen VI chains, alpha4(VI), alpha5(VI), and
            alpha6(VI)
  JOURNAL   J Biol Chem 283 (29), 20170-20180 (2008)
   PUBMED   18400749
  REMARK    GeneRIF: discovery of three additional collagen VI chains doubles
            the collagen VI family and adds a layer of complexity to collagen
            VI assembly and function in the extracellular matrix
REFERENCE   10 (bases 1 to 7388)
  AUTHORS   Gara,S.K., Grumati,P., Urciuolo,A., Bonaldo,P., Kobbe,B., Koch,M.,
            Paulsson,M. and Wagener,R.
  TITLE     Three novel collagen VI chains with high homology to the alpha3
            chain
  JOURNAL   J Biol Chem 283 (16), 10658-10670 (2008)
   PUBMED   18276594
  REMARK    GeneRIF: analysis of collagen VI chains alpha4, alpha5, and
            alpha6with high homology to the alpha3 chain
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120386.12.
            
            On Dec 22, 2022 this sequence version replaced NM_026763.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB370265.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-127               AC120386.12        3832-3958
            128-216             AC120386.12        17660-17748
            217-819             AC120386.12        20068-20670
            820-1407            AC120386.12        23156-23743
            1408-2016           AC120386.12        25185-25793
            2017-2661           AC120386.12        28057-28701
            2662-3207           AC120386.12        32223-32768
            3208-3762           AC120386.12        33409-33963
            3763-4097           AC120386.12        37508-37842
            4098-4176           AC120386.12        39055-39133
            4177-4322           AC120386.12        40146-40291
            4323-4415           AC120386.12        40482-40574
            4416-4469           AC120386.12        43181-43234
            4470-4541           AC120386.12        48911-48982
            4542-4568           AC120386.12        50757-50783
            4569-4613           AC120386.12        52856-52900
            4614-4667           AC120386.12        56337-56390
            4668-4730           AC120386.12        59461-59523
            4731-4796           AC120386.12        59978-60043
            4797-4850           AC120386.12        66633-66686
            4851-4886           AC120386.12        66824-66859
            4887-4949           AC120386.12        70586-70648
            4950-5012           AC120386.12        72363-72425
            5013-5075           AC120386.12        74097-74159
            5076-5138           AC120386.12        75062-75124
            5139-5189           AC120386.12        77691-77741
            5190-5225           AC120386.12        79814-79849
            5226-5288           AC120386.12        79951-80013
            5289-5351           AC120386.12        81149-81211
            5352-5387           AC120386.12        82726-82761
            5388-5424           AC120386.12        84083-84119
            5425-5436           AC120386.12        86722-86733
            5437-5930           AC120386.12        86818-87311
            5931-6021           AC120386.12        97346-97436
            6022-6705           AC120386.12        99720-100403
            6706-6802           AC120386.12        103394-103490
            6803-7014           AC120386.12        104483-104694
            7015-7388           AC120386.12        109781-110154
FEATURES             Location/Qualifiers
     source          1..7388
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 57.39 cM"
     gene            1..7388
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /note="collagen, type VI, alpha 4"
                     /db_xref="GeneID:68553"
                     /db_xref="MGI:MGI:1915803"
     exon            1..127
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            128..216
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            217..819
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            820..1407
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..2016
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            2017..2661
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            2662..3207
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            3208..3762
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            3763..4097
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4098..4176
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4177..4322
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4323..4415
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4416..4469
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4470..4541
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4542..4568
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4569..4613
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4614..4667
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4668..4730
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4731..4796
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4797..4850
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4851..4886
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4887..4949
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            4950..5012
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5013..5075
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5076..5138
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5139..5189
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5190..5225
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5226..5288
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5289..5351
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5352..5387
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5388..5424
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5425..5436
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5437..5930
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            5931..6021
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            6022..6705
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            6706..6802
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            6803..7014
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     exon            7015..7388
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7359..7364
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /note="hexamer: ATTAAA"
     polyA_site      7388
                     /gene="Col6a4"
                     /gene_synonym="1110001D15Rik; Dvwa; EG235580; Vwa6"
                     /note="major polyA site"
ORIGIN      
        1 gctcctccag gcttcctgtg tgctagggga ttcccaggct cacacgggct ctgagggatg
       61 aggacaagga gagcttgaag aagccagcct ccccagggtg ccagctaaga accagctctt
      121 cctaggggat cacatctatc atgggaactt ggaagacatt ttggttgatc atctcccttg
      181 cagctggttt gggcttcgtc aagtcacaga ggattgtctg cagggaggcg tctgtgggag
      241 acattgtgtt tctggtccac aacagcatca atccccagca tgcccacagt gtgcggaact
      301 tcttgtacat attggcaaac agtttgcaag ttggcagaga caacatccgt gtgggtctgg
      361 cccagtacag cgatacaccc acttctgagt tcctgctttc agtttatcac cgcaaaggcg
      421 atgtgttgaa acacatccgt ggacttcagt ttaagcctgg aggcaacagg atgggccagg
      481 ccctgcagtt catcttagag catcacttcc gggaaggagc cgggagccgg gcaagccaag
      541 gggtgcctca ggtggccgtg gtggtgagca gcggtctaac agaggaccac attcgcgaac
      601 ctgcggaggc tctcaggaga gcgggaatct tggtatacgc tattggggtc aaagacgcat
      661 ctcaggctga actcagggag atttcgagta gtcccaagga taacttcacc ttttttgttc
      721 ccaacttccc tggcttgcct ggccttgccc agaagctgcg gccagagctc tgcagtactc
      781 tagggaaggc agctcaatat actgagcggg agtctccagc gtgctcagaa gcatccccgg
      841 ctgacattgt gtttttggtg gacagttcaa ctagcatcgg actccagaac ttccagaaag
      901 tgaagcattt cctccactct gttgtctcgg ggctcgacgt cagaagcgat caggtgcaag
      961 tggggctggt ccagtacagt gacaacattt acccagcctt tccgctgaag cagtcctctc
     1021 tgaagagcgc cgtcctggat cggatccgga atctgcccta cagcatgggg ggcacaagta
     1081 ccggaagcgc cctggagttc atcagggcca actccttgac tgagatgagt ggcagccgtg
     1141 ccaaggatgg ggttcctcag atagttgtcc tggtgacaga tggggagtcc agtgatgagg
     1201 tccaggatgt ggctgaccag ctgaaaagag acggggtctt tgtgtttgtg gtagggatca
     1261 atattcaaga tgtccaagag ttgcagaaaa tagccaacga gccgtttgag gagtttctct
     1321 tcaccacaga aaacttcagc atcttgcagg cgctctcagg aaccctcctt caggccctgt
     1381 gttccacggt ggagaggcag atgaaaaagt ctaccaagac ctacgcagac gtggtctttc
     1441 ttattgacac ctcccagggg acatcacagg ctagtttcca gtggatgcag aatttcatct
     1501 ctagaattat tggcatcctg gaggtcggcc aggacaaata ccagattggg ctggctcagt
     1561 atagcgatca aggtcacact gagtttttgt tcaataccca caagacccgg aatgagatgg
     1621 tcgcacacat ccatgaactc ttggtgttcc aaggtggctc caggaagact ggccaaggcc
     1681 ttcggtttct tcatcggact ttcttccagg aggcagcagg aagccggctc ttacagggtg
     1741 tccctcagta tgtggtagtc attacttcag ggaaatctga ggacgaggtc ggagaggtcg
     1801 cacagatcct gaggaagaga ggcgtggaca tcgtgtctgt gggcttgcag gactttgaca
     1861 gggcagaact ggaggggata gggcctgtag tgcttgtgtc tgacctgcag ggagaagata
     1921 gaatcagaca gctaatgctg gatgtgaata tgttcatcca ggggagtcca aagcctccac
     1981 gggtcatgac tgatgttgcg aaggacgctg tagaagaatg tctagttccc gttccagccg
     2041 acctggtgtt ccttgttgag gactttagca gtgccaggca acccaatttc cagcgagttg
     2101 tccatttctt gacgaccact gtccactctc tcaacatcca tcctgatacc acaagagtca
     2161 gcttggtctt ttacagtgag aaaccaaggc tggagttttc cctggatatg tatcaaagcg
     2221 ctgcccaagt cttacgccat ctggacaggt taactttccg agcaagaaga ggaagggcga
     2281 aggcaggtgc tgctttagac ttcctgagga aagaagtttt ccttccagag aagggcagcc
     2341 ggccccatcg gggcgtacag cagatagctg tggtcatcat agaaagtcct tctctagaca
     2401 atgtgtctac acctgcttcc taccttcgca gggcgggggt caccatctat gcagcgggca
     2461 cccagcctgc ctctgagagt aaggacctgg agaagattgt cacataccct ccctggaagc
     2521 acgccatccg cctagagtcc tttctgcaac tcagtgttgt aggaaacaaa cttaaaaaga
     2581 agctctgccc tgagatgttg agcggaatgc ctcctctgat gagctttatt ccagaaagca
     2641 cacgacaaag cacacaggaa ggctgcgaga gtgtggagaa ggcagacatt tacttcctta
     2701 ttgatggatc tggcagcatc aaacccaacg acttcattga aatgaaggac ttcatgaagg
     2761 aggtgataaa gatgttccac attgggcccg acagagtacg atttggagtc gttcagtact
     2821 cagacaaaat tataagccag tttttcctca cccagtatgc cagcatggca ggactgagcg
     2881 cagccattga caacatccaa caggtgggag gtggtaccac cactggcaag gccttaagca
     2941 aaatggtacc agtcttccaa aacactgcca gaatcgacgt tgcccgatac ctcattgtca
     3001 tcactgatgg tcagtctacc gacccggtgg ctgaggctgc gcagggattg agggacatcg
     3061 gagtcaatat ttatgccatt ggagtaaggg atgctaatac gactgagctt gaggaaatag
     3121 caagcaaaaa gatgtttttc atatatgagt ttgattcctt gaagtccatc caccaggaag
     3181 tcattcggga catctgctcc tcagagaact gtaagagcca gaaagctgac atcatcttct
     3241 tgattgatgg ctcagaatcc atcgctccta aagactttga aaagatgaag gacttcatgg
     3301 agaggatggt gaaccagtct aatatcggtg ctgatgaaat tcagattggc cttctgcagt
     3361 tcagctccaa tccccaggaa gaattcaggc ttaaccggta ctcctcaaag gtggacatgt
     3421 gcagagccat cttgagtgtc caacagatga gtgatggtac ccatactggg aaagccttga
     3481 atttcactct gccctttttt gacagttcaa gaggagggag acccagagtt catcagtatt
     3541 tgattgtgat caccgacggg gtctcccagg ataatgtagc tcccccagcc aaagccctca
     3601 gggacagaaa cataattatt tttgctatcg gggtgggaaa tgttcaaaga gcccagcttt
     3661 tggagatcac caatgaccag gacaaagtat tccaggagga aaattttgag tccctgcaga
     3721 gcctggaaaa ggaaattctt tctgaggtct gtagttccca aggctgcaac atagatctgt
     3781 ctgtaggagt tgatacctca acctcttcag agcgagctca gcaggagctt cgaaggttgc
     3841 tgccggagct gatgcaacag ctggcttttc tctctaacat cagctgtgag gctcctggcc
     3901 agatggagcc gaggttccga tatgtggttc caggctccag cgaccagcct gtctttgatt
     3961 ccggctttga gaaatacagc gatgagacca tccagaagtt cttggtgcat cagggttctg
     4021 taaacaaccg tatggatgta gactttctgc agtccctggg agagactgcc attcacctgt
     4081 ctcttgctaa agtgaaggtc cttttagtgt ttacagacgg acttgatgaa gacctagaga
     4141 ggctgaggag aacctcagag ttccttcgca gcagagggct ctccggactg ctgctcatcg
     4201 gcctgggagg tgcacataag ttagaagagc tgcaggagct ggagtttggc agagggtttg
     4261 cctacaggca gcctctgagc tccagtctgc catccctccc aagcgtctta ctgaagcaac
     4321 tcgacacaat tgtggagagg acatgctgta acatgtatgc caaatgttac ggagacgatg
     4381 ggatcagagg tgaacctggg agtcgagggg agcagggaga gaggggtttg gacgggctcc
     4441 ctggccatcc tggtgaagag ggagaccacg gacaaagagg cccccgaggt cttcctggac
     4501 ttcgaggtga ggaaggatgt ccaggtgtga gaggacctaa gggagcaaga ggattttcag
     4561 gagagaaggg caaccctggt gaggaaggtg ttgggggctt ggatggagaa cagggcgatc
     4621 gtggagccgc agggccatct ggagagaaag gaagcagcgg cagtcggggc ttgacaggtc
     4681 tgcctggacc agctggacct cgtggggagc ctgggctgag gggagatccg ggggatcctg
     4741 gaattgataa tctcatccaa ggccccaagg gagaaaaggg aaggcgtgga catcagggaa
     4801 gccctggttt ccatggacct ctgggggaag ccggcagtgt gggacctcgg gggtcacttg
     4861 gaagacatgg cttgccaggg ttgaagggtg tgcttggaga aaccggtgag ctgggttccc
     4921 gaggagagcc tgggcatcca ggcccacagg gacccagagg aaggcaagga ccaccaggat
     4981 ttttcggtca aaaaggggat ccgggtaccc aggggaatcc tgggcttcca gggccaagtg
     5041 gctcaaaagg accagatgga cccagaggac tgaagggaga agtcggtcct gcaggagaaa
     5101 gaggtccacg gggtcagcaa ggcccaagag ggcagcctgg tcttttcggt ccagacggcc
     5161 atggttatcc gggaagaaaa ggcaggaagg gtgaacctgg gttccctggc tatcctggtg
     5221 tgcaaggaga agatggtaac ccaggccgtg gaggagagaa gggggccaag ggaatccgag
     5281 ggaagagggg caattctgga tttcctgggc ttgctggaac tccaggtgac caaggcccac
     5341 cgggaaaaat gggcaccaaa ggctcgaaag gcttggcaga taggacgcct tgtgaaattg
     5401 ttgacttcgt gcgaggaaac tgcccttgct caacaggtat ttccaggtgc ccagcattcc
     5461 caacagaagt ggtcttcacc ttggacatgt ccaacgatgt cgccccatca gactttgaga
     5521 ggatgagaaa cattttatta tctctgctga tgaagctgga aatgtgcgag agcaactgtc
     5581 ccactggtgc ccgagtggcc attgtttcct acaacacgag gacagattac ctagtgcgct
     5641 tgtcagacca tcggggaaaa gctgcccttc tgcaggctgt caggaaaatc cccctggaac
     5701 gctcatctgg gtctcggaac cttggggcca ctatgaggtt tgtggctaga cacgtattca
     5761 aacgtgtacg ctcaggcctt ctggtgagga aggtggccgt gttcttccag gcaggtagga
     5821 actatgacac agcctctgtc agcacagcca cgttggagct ccacgcagcg gacattgcta
     5881 cagcagttgt gaccttcaca gaggagcaca acctcccaga ggcagggctg gtggatggac
     5941 ccaacgaatt tcacctgttt acgtgggaga ccgagggcca gcaggatgtg gaacgcctgg
     6001 ccagctgtac tctctgctat gacaagtgcc gaccagccct ggggtgccag ctgcgtgctc
     6061 ctgggcctca gaagttggac atggacttgg tattcctggt ggacagctcc cagggtgtca
     6121 gcagggacat ataccttggg gctttgcggc tagtggattc agtgctcaag gacctggagg
     6181 tggctgcgca gcctggcaca tcctggcacg gggcgcgcgc agccctgttg acacacacaa
     6241 ccccaggctt ttggcctggt gtggatcaag cccctgtgct tgagtacttc cacctgacct
     6301 cccacggcca ccggacagaa atgcaaaggc agattcggga ggctgcgagt ggcctgctac
     6361 agggaggccc cgccctgggc cacgccctgg agtggacgct ggaaaacgtg cttctgacag
     6421 ccgtactgcc tcggaggtca cgggtcctct atgccatcgt ggccagcgag acaagcatct
     6481 gggacagaga gaagctaagg actctgtccc aggaggccaa gtgcaagggc atcgcattat
     6541 tcgtgctcgc cgtgggccct ggagtgggcg cccaggagct ggctgagctg gccaaagtgg
     6601 ccagtgcgcc ctgggagcag cacctgctac gcctagaggg tgtctcagag gcagaggtgg
     6661 cctatgccag cagattcacg gaggccttcc tgaaccttct aaatagtgga ataaaccagt
     6721 atccaccccc agagcttgtt aaggagtgtg gaggcccaaa ccgtggggac accttgctgc
     6781 atttcttcac ttctgccaag aggttttcca ggagccagtc tggcacgtct gctgcctttg
     6841 cgaatgactc agaagcactc aagtcacagg gcatctttct aggggagagg aaaagcaggg
     6901 tggcgtccgt agctctgcaa gaagcgttgg gaagtcatgg gaaggacagg gcggacactg
     6961 aagacattga tcaggaaacg ccagcaaaag gaagacattt gggccccacc cacggtcctt
     7021 gtcccatggg tcctgaggaa ggcgagtgcc tgaattatgt cttgaagtag tactacagcc
     7081 aggaagaaga agcttgctac cgcctctggt ttggggactg tgggggcaag gccaaccagt
     7141 ctgaaaccag agaagagtgt gagacatggt gtaggccaag ccttgtaact gacgcccttc
     7201 ctttaacggc gagacagtga gactggcgtt acccttgctg agacaggctt cccagctcat
     7261 gactgacaaa ccccaccctg tagccctgga tattctaact ccctccactg ttttcctgcc
     7321 tgtgaaggct taggctagat catttgtaac ggagaaggat taaattctat ttttccctca
     7381 ttgtaaaa
//
