LOCUS       NM_001037865            4230 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus collagen, type XXVIII, alpha 1 (Col28a1), mRNA.
ACCESSION   NM_001037865 XM_145161 XM_889328 XM_910111 XM_910164
VERSION     NM_001037865.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4230)
  AUTHORS   Li,L., Ye,H., Chen,Q. and Wei,L.
  TITLE     COL28 promotes proliferation, migration, and EMT of renal tubular
            epithelial cells
  JOURNAL   Ren Fail 45 (1), 2187236 (2023)
   PUBMED   36883360
  REMARK    GeneRIF: COL28 promotes proliferation, migration, and EMT of renal
            tubular epithelial cells.
REFERENCE   2  (bases 1 to 4230)
  AUTHORS   Li,L., Zou,Q., Li,B., Huang,L. and Wei,L.
  TITLE     Type XXVIII Collagen Regulates Renal Interstitial Fibrosis and
            Epithelial-Mesenchymal Transition by SREBP1-Mediated HKDC1
            Expression
  JOURNAL   J Renin Angiotensin Aldosterone Syst 2022, 9582559 (2022)
   PUBMED   36518326
  REMARK    GeneRIF: Type XXVIII Collagen Regulates Renal Interstitial Fibrosis
            and Epithelial-Mesenchymal Transition by SREBP1-Mediated HKDC1
            Expression.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4230)
  AUTHORS   Naba,A., Clauser,K.R., Mani,D.R., Carr,S.A. and Hynes,R.O.
  TITLE     Quantitative proteomic profiling of the extracellular matrix of
            pancreatic islets during the angiogenic switch and insulinoma
            progression
  JOURNAL   Sci Rep 7, 40495 (2017)
   PUBMED   28071719
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4230)
  AUTHORS   Naba,A., Clauser,K.R., Hoersch,S., Liu,H., Carr,S.A. and Hynes,R.O.
  TITLE     The matrisome: in silico definition and in vivo characterization by
            proteomics of normal and tumor extracellular matrices
  JOURNAL   Mol Cell Proteomics 11 (4), M111.014647 (2012)
   PUBMED   22159717
REFERENCE   5  (bases 1 to 4230)
  AUTHORS   Grimal,S., Puech,S., Wagener,R., Venteo,S., Carroll,P. and
            Fichard-Carroll,A.
  TITLE     Collagen XXVIII is a distinctive component of the peripheral
            nervous system nodes of ranvier and surrounds nonmyelinating glial
            cells
  JOURNAL   Glia 58 (16), 1977-1987 (2010)
   PUBMED   20830809
  REMARK    GeneRIF: The correlation between the absence of myelin and the
            presence of collagen XXVIII is confirmed in a mouse model of
            Charcot-Marie-Tooth characterized by dysmyelinated nerve fibers, in
            which enhancement of collagen XXVIII labeling is observed
REFERENCE   6  (bases 1 to 4230)
  AUTHORS   Veit,G., Kobbe,B., Keene,D.R., Paulsson,M., Koch,M. and Wagener,R.
  TITLE     Collagen XXVIII, a novel von Willebrand factor A domain-containing
            protein with many imperfections in the collagenous domain
  JOURNAL   J Biol Chem 281 (6), 3494-3504 (2006)
   PUBMED   16330543
  REMARK    GeneRIF: Collagen XXVIII is a novel von Willebrand factor A
            domain-containing protein with many imperfections in the
            collagenous domain
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ890449.1.
            
            On or before Dec 21, 2005 this sequence version replaced
            XM_889328.1, XM_145161.5, XM_910111.1, XM_910164.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ890449.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4230
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 3.44 cM"
     gene            1..4230
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /note="collagen, type XXVIII, alpha 1"
                     /db_xref="GeneID:213945"
                     /db_xref="MGI:MGI:2685312"
     exon            1..93
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            94..254
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..3556
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /function="extracellular matrix protein"
                     /note="collagen alpha-1(XXVIII) chain; collagen 28"
                     /codon_start=1
                     /product="collagen alpha-1(XXVIII) chain precursor"
                     /protein_id="NP_001032954.1"
                     /db_xref="CCDS:CCDS39424.1"
                     /db_xref="GeneID:213945"
                     /db_xref="MGI:MGI:2685312"
                     /translation="MRRRDVAFCLLLLPAFMTQAVYGQRKKGPKPNTLARKNDFQDAI
                     CFIDVVFILDSSESSKIVLFDNQKDFVDSLSEKIFQLTPGRSLKYDIKLAALQFSSSV
                     QIDPPLSSWKDLRTFKQRVKSLNLIGQGTFSYYAISNATRLLKREGRKDGVKVALLMT
                     DGIDHPKSPDVQSISEDARILGISFITVGLSTVVNEAKLRLISGDPSNEPVLLLSDPT
                     LVDRIQERLGVLFERKCEHKICECEKGEPGDPGPPGTHGNPGIKGERGPKGNPGDAQK
                     GETGERGPVGIPGYKGDKGERGECGKPGMKGDKGPEGPYGPKGPRGIQGIGGPPGDPG
                     PKGFQGNKGEPGPPGPYGPPGAPGIGQQGVKGERGQEGRMGAPGPIGIGEPGQPGPRG
                     PEGAPGERGLPGEGFPGPKGEKGSEGPIGPQGLQGLSIKGDKGDLGPVGPQGPAGIPG
                     IGSQGEQGIQGPSGPPGPQGPPGQGSPGPKGEVGQMGPTGPRGPMGIGVQGPKGEPGT
                     VGLPGQPGVPGEDGASGKKGEAGLPGTRGPEGMPGKGQPGPKGDEGKKGSKGNQGQRG
                     FPGPEGPKGEPGVMGPFGMPGASIPGPSGPKGDRGGPGMPGLKGEPGLPVRGPKGAQG
                     PRGPVGAPGLKGDGYPGVAGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG
                     IGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGSKGTVGLGLPGQKGEHGD
                     RGDVGRKGEKGETGEPGSPGKQGLQGPKGDLGLTKEEIIKLIIEICGCGPKCKETPLE
                     LVFVIDSSESVGPENFQIIQSFVKTLADRVALDLGTARIGIINYSHKVEKVASLKQFS
                     SKDDFKLVVDNMQYLGEGTYTATALQAANDMFKEARPGVKKVALVITDGQTDSRDKKK
                     LADVVKDANDSNVEIFVIGVVKKDDPNFEIFHKEMNLIATDAEHVYQFDDFFTLQDTL
                     KQKLSKKICEDFDSYLIQVFGSPSFQPEFGVSEREVSVSTPKPAKEMSKSFNVSRGQN
                     EETESYVLTEAGILAIPTPPEATNTLEPLLSSREGVETRTPNPNLLQSEKSLYKDPRC
                     EEALKPGECGDYVVRWYYDKQVNSCARFWFSGCNGSGNRFHSEKECRETCIKQ"
     exon            255..811
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            812..832
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            833..889
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            890..943
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            944..985
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1012
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1057
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1102
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1156
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1225
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1294
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1363
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1432
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1501
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1570
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1639
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1640..1711
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1712..1780
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1781..1852
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1853..1921
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1922..1990
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            1991..2059
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            2060..2128
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            2129..2197
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            2198..2266
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            2267..2335
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            2336..2416
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            2417..2452
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            2453..2489
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..3038
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            3039..3196
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            3197..3383
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     exon            3384..4230
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3545..3550
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /note="hexamer: ATTAAA"
     polyA_site      3565
                     /gene="Col28a1"
                     /gene_synonym="Col28; Gm466"
                     /note="major polyA site"
ORIGIN      
        1 tcttcatcaa acccctgccc tcaaggctca agttctatgc agaagagttg atgatggaag
       61 actccaggaa agcagtgtct ccagacacaa caggtgttac caggcagatg aatttttacc
      121 atctaccata atgaggagaa gagacgttgc cttctgtctt ctgcttttgc cagcttttat
      181 gactcaagca gtgtatggac aaagaaagaa aggaccaaag ccaaacacac ttgcaaggaa
      241 aaatgacttc caggatgcca tttgcttcat agatgttgtc tttatcttgg acagctcaga
      301 aagctccaaa attgtactct ttgataatca gaaagatttt gtggacagct tgagtgagaa
      361 gattttccag ttgactcctg gccgttcatt aaaatatgac atcaagctgg cagcccttca
      421 gtttagcagc tcggtccaga ttgatccacc cttgtcttct tggaaggatc tccggacatt
      481 taagcagcgg gtcaagtctc tgaatttaat tgggcaaggt accttttctt attatgccat
      541 ctccaatgcc acaaggctac ttaaaagaga agggcgtaaa gatggcgtga aggtggcttt
      601 gctgatgact gatggcatcg atcatcccaa gagcccagat gtccaaagta tttctgaaga
      661 tgctagaatt ttgggaatat catttatcac cgttggactt tccactgtgg tcaatgaagc
      721 caaacttcgt ttgatatctg gggatccttc caatgaaccc gttctactat tgagtgaccc
      781 aacacttgta gacagaattc aggaacgcct gggtgtcttg tttgaaagga agtgtgaaca
      841 caagatctgt gaatgtgaaa agggcgagcc aggtgaccca gggcctcctg gtacccatgg
      901 aaaccctggt atcaaaggtg agcgaggacc aaaaggaaac ccgggtgatg ctcagaaagg
      961 agaaactgga gaaagaggtc ctgtgggaat ccctgggtac aagggtgaca agggtgaacg
     1021 aggagaatgt gggaaaccag gaatgaaagg tgacaaagga cctgaagggc catatggacc
     1081 aaagggacca agaggaattc agggcattgg tggacctcca ggggatccag gtccaaaggg
     1141 atttcaagga aataagggtg agccaggtcc tcctggtcct tatggtcctc caggagcccc
     1201 tggtattgga cagcaaggtg ttaagggtga gaggggccag gaaggaagaa tgggagctcc
     1261 cggaccgatt ggaattggtg aacccggaca gccaggtccc cgtggtcctg agggagcacc
     1321 aggagagcgg ggcctaccag gagaaggatt tcctggacct aagggtgaaa agggatctga
     1381 aggaccaatc ggcccacaag gattacaagg cctgtcaatc aaaggggata agggggattt
     1441 gggacctgtg ggaccgcagg ggccagcggg aattcctggc atcggaagcc aaggcgagca
     1501 ggggatccaa ggtccatctg gtccacctgg tcctcaagga cccccaggac aaggctcacc
     1561 tggtcctaag ggagaagtag gtcagatggg acccacaggg cctagaggac caatgggcat
     1621 tggagtacag ggtccaaagg gggagccagg cacagtgggg ctcccaggac agcctggagt
     1681 cccaggggaa gatggggcct ctggaaagaa gggagaagct ggacttccag gaacaagagg
     1741 cccagaagga atgcctggga aaggacagcc cggccccaag ggtgatgaag gaaagaaagg
     1801 gagcaaagga aatcaaggac agagggggtt tccaggaccc gaagggccaa agggagagcc
     1861 aggtgttatg ggccccttcg gaatgcccgg agcctcaatt cctggaccat ctggaccaaa
     1921 gggagaccga ggaggacctg gcatgcctgg tcttaaagga gaacctggac ttcctgttcg
     1981 aggaccaaag ggtgcccagg gtccccgagg accagtgggg gctccaggac tcaaaggtga
     2041 tggctatcct ggtgtggctg gaccgcgagg attgccagga ccccctggac caatgggctt
     2101 acgtggtgtg ggagacactg gagcaaaggg agaaccagga gtcagaggcc ctccaggtcc
     2161 ctctgggcct cggggaatag gaacccaagg accaaagggt gatactgggc aaaagggcct
     2221 gcctggccct cctgggcccc ctggctatgg atcacaagga attaaagggg agcaaggacc
     2281 tcaaggtttc ccagggtcaa agggcacagt gggccttggc ctccctggtc agaagggaga
     2341 gcatggagac cggggtgatg tgggaaggaa aggcgaaaag ggagaaactg gagagcctgg
     2401 gtctccagga aaacaggggt tacaaggacc taaaggagac ctgggactca caaaagaaga
     2461 aattatcaaa cttatcattg aaatatgtgg ttgtgggccc aaatgcaaag agactccact
     2521 ggagttggtg tttgtgattg acagttcaga aagtgtggga ccagagaact ttcagatcat
     2581 ccaaagtttt gtgaagactt tggctgaccg ggtggccttg gaccttggca cagcccggat
     2641 aggcataatc aactatagcc acaaggtgga gaaggtggct agcctgaagc agttttccag
     2701 caaggatgac ttcaagctgg tggtagacaa catgcagtat ctgggggaag gcacctatac
     2761 agccactgct cttcaagcag ctaatgacat gttcaaagag gcaaggccag gtgtaaagaa
     2821 ggtggccttg gtgatcacgg atggacagac agattcccga gataaaaaga agctggcaga
     2881 tgtggtgaag gatgccaatg actccaacgt ggaaatattt gtcattggag tggtgaagaa
     2941 ggatgacccc aactttgaaa tttttcacaa agaaatgaat ctcattgcta ctgatgcaga
     3001 acatgtgtat cagtttgacg acttctttac cctgcaagat actctgaagc aaaagttgtc
     3061 taaaaaaatt tgtgaagatt ttgactccta tctcattcaa gtttttggat caccatcttt
     3121 tcaacctgaa tttggggtat cagaacgaga ggtcagcgta tccactccaa agcctgcaaa
     3181 agaaatgtct aagtcgttta atgtttctag aggccaaaat gaagagactg aatcgtatgt
     3241 gttgactgag gctggtatct tggccatccc aaccccacct gaagccacca atacacttga
     3301 gccattactc agcagccgtg aaggagtgga aacaagaact ccaaatccca atttgttaca
     3361 gtcagaaaaa tctctgtaca aagatccaag atgcgaggaa gccctgaagc ccggggaatg
     3421 tggcgactac gtggttcgct ggtattacga caaacaggtc aactcttgcg ctcgcttttg
     3481 gttcagtggc tgcaatggct caggaaacag attccacagt gaaaaagaat gtcgagaaac
     3541 ctgcattaaa caatgaacaa gcacagtaac gggcttcgat cagaggttta gagagagtgt
     3601 gatacaaaca gtgcaccaca tctgagcata cactgactga gtacagacct tcataaatgg
     3661 catagaccac cttctaggga tacagtctga ttaagtgcct acacagctga agggtggaag
     3721 gactgggatc tgaactcagc tgtgtaactt tagaacacag actccatctt gcttcacaac
     3781 ctgtggtgtg gccctgatgc ctcgtcattc tagtacacaa acaatgacag gtcacacccc
     3841 accctccctg tgcccacacc gttccagcac cttcacaacc catcagtgga gagtggtttg
     3901 tgaggggagg gactttggtt tgaacactgt aggaatgtct acatgtgaat gctggggtag
     3961 tggtgaagga tggtgaggag agttaagaat ttagcccaaa gtgatggtag aaatatgtct
     4021 gaatactcac taacagtatg ataagttgac tcttcctgtt cctcattggt gtcaaagcct
     4081 tcactgtaca ctaaagctat gtattaaaat aaagcaggtt ttacattttt cctttaaaaa
     4141 catgtgaatg agactggatt ttatggccaa ggagtgagac catcatttta taataatttt
     4201 gttataccaa gtgtggggag acagagagtt
//
