LOCUS       NM_153393               5665 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus collagen, type XXIII, alpha 1 (Col23a1), mRNA.
ACCESSION   NM_153393 XM_910172
VERSION     NM_153393.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5665)
  AUTHORS   Feng,W., Bais,A., He,H., Rios,C., Jiang,S., Xu,J., Chang,C.,
            Kostka,D. and Li,G.
  TITLE     Single-cell transcriptomic analysis identifies murine heart
            molecular features at embryonic and neonatal stages
  JOURNAL   Nat Commun 13 (1), 7960 (2022)
   PUBMED   36575170
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5665)
  AUTHORS   Zhou,C., Chen,D., Ren,J., Huang,D., Li,R., Luo,H., Guan,C., Cao,Y.
            and Wang,W.
  TITLE     FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme
            proliferation and differentiation via Lhx8/Suv39h1 complex
  JOURNAL   J Cell Mol Med 25 (6), 3051-3062 (2021)
   PUBMED   33580754
REFERENCE   3  (bases 1 to 5665)
  AUTHORS   Caubit,X., Gubellini,P., Andrieux,J., Roubertoux,P.L., Metwaly,M.,
            Jacq,B., Fatmi,A., Had-Aissouni,L., Kwan,K.Y., Salin,P.,
            Carlier,M., Lieden,A., Rudd,E., Shinawi,M., Vincent-Delorme,C.,
            Cuisset,J.M., Lemaitre,M.P., Abderrehamane,F., Duban,B.,
            Lemaitre,J.F., Woolf,A.S., Bockenhauer,D., Severac,D., Dubois,E.,
            Zhu,Y., Sestan,N., Garratt,A.N., Lydia Kerkerian-Le,Goff. and
            Fasano,L.
  TITLE     TSHZ3 deletion causes an autism syndrome and defects in cortical
            projection neurons
  JOURNAL   Nat Genet 48 (11), 1359-1369 (2016)
   PUBMED   27668656
REFERENCE   4  (bases 1 to 5665)
  AUTHORS   Bildsoe,H., Fan,X., Wilkie,E.E., Ashoti,A., Jones,V.J., Power,M.,
            Qin,J., Wang,J., Tam,P.P.L. and Loebel,D.A.F.
  TITLE     Transcriptional targets of TWIST1 in the cranial mesoderm regulate
            cell-matrix interactions and mesenchyme maintenance
  JOURNAL   Dev Biol 418 (1), 189-203 (2016)
   PUBMED   27546376
REFERENCE   5  (bases 1 to 5665)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   6  (bases 1 to 5665)
  AUTHORS   Naba,A., Clauser,K.R., Hoersch,S., Liu,H., Carr,S.A. and Hynes,R.O.
  TITLE     The matrisome: in silico definition and in vivo characterization by
            proteomics of normal and tumor extracellular matrices
  JOURNAL   Mol Cell Proteomics 11 (4), M111.014647 (2012)
   PUBMED   22159717
REFERENCE   7  (bases 1 to 5665)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 5665)
  AUTHORS   Veit,G., Zimina,E.P., Franzke,C.W., Kutsch,S., Siebolds,U.,
            Gordon,M.K., Bruckner-Tuderman,L. and Koch,M.
  TITLE     Shedding of collagen XXIII is mediated by furin and depends on the
            plasma membrane microenvironment
  JOURNAL   J Biol Chem 282 (37), 27424-27435 (2007)
   PUBMED   17627939
REFERENCE   9  (bases 1 to 5665)
  AUTHORS   Koch,M., Veit,G., Stricker,S., Bhatt,P., Kutsch,S., Zhou,P.,
            Reinders,E., Hahn,R.A., Song,R., Burgeson,R.E., Gerecke,D.R.,
            Mundlos,S. and Gordon,M.K.
  TITLE     Expression of type XXIII collagen mRNA and protein
  JOURNAL   J Biol Chem 281 (30), 21546-21557 (2006)
   PUBMED   16728390
  REMARK    GeneRIF: analysis of collagen XXIII mRNA and protein
REFERENCE   10 (bases 1 to 5665)
  AUTHORS   Desai,J., Shannon,M.E., Johnson,M.D., Ruff,D.W., Hughes,L.A.,
            Kerley,M.K., Carpenter,D.A., Johnson,D.K., Rinchik,E.M. and
            Culiat,C.T.
  TITLE     Nell1-deficient mice have reduced expression of extracellular
            matrix proteins causing cranial and vertebral defects
  JOURNAL   Hum Mol Genet 15 (8), 1329-1341 (2006)
   PUBMED   16537572
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL645907.9 and
            AL662843.11.
            
            On Sep 7, 2007 this sequence version replaced NM_153393.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF410792.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-468               AL645907.9         88824-89291
            469-535             AL645907.9         115800-115866
            536-580             AL662843.11        75318-75362
            581-588             AL662843.11        84064-84071
            589-615             AL662843.11        85980-86006
            616-642             AL662843.11        107805-107831
            643-669             AL662843.11        109246-109272
            670-696             AL662843.11        110088-110114
            697-813             AL662843.11        115583-115699
            814-849             AL662843.11        116541-116576
            850-876             AL662843.11        118119-118145
            877-903             AL662843.11        120001-120027
            904-957             AL662843.11        121112-121165
            958-1020            AL662843.11        122853-122915
            1021-1065           AL662843.11        123289-123333
            1066-1143           AL662843.11        126008-126085
            1144-1197           AL662843.11        127573-127626
            1198-1242           AL662843.11        128214-128258
            1243-1332           AL662843.11        129286-129375
            1333-1395           AL662843.11        130180-130242
            1396-1452           AL662843.11        130568-130624
            1453-1479           AL662843.11        130870-130896
            1480-1542           AL662843.11        132113-132175
            1543-1596           AL662843.11        132259-132312
            1597-1623           AL662843.11        132544-132570
            1624-1677           AL662843.11        134963-135016
            1678-1764           AL662843.11        135186-135272
            1765-1803           AL662843.11        137687-137725
            1804-5665           AL662843.11        138176-142037
FEATURES             Location/Qualifiers
     source          1..5665
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 31.03 cM"
     gene            1..5665
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /note="collagen, type XXIII, alpha 1"
                     /db_xref="GeneID:237759"
                     /db_xref="MGI:MGI:2653243"
     exon            1..468
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             208..1806
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /note="procollagen, type XXIII, alpha 1"
                     /codon_start=1
                     /product="collagen alpha-1(XXIII) chain"
                     /protein_id="NP_700442.2"
                     /db_xref="CCDS:CCDS24652.1"
                     /db_xref="GeneID:237759"
                     /db_xref="MGI:MGI:2653243"
                     /translation="MGAGERAAGGGGAQDPGAGCGSRALSALCLLLSVGSAAACLLLG
                     AQAAALHGRVAALEQERELLRHAGPSGALAAWAETHLERLLREKLDGVAKLRTVREAP
                     SECICPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGTPGDF
                     GPRGAQGQDGVAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPRGEPGQDGEMGPKG
                     PPGPKGEPGIPGKKGDDGMANQPGLPGPPGPKGEPGDVGPRGENGVDGIPGLKGEPGH
                     PGVDGATGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGAPGPPGIPGAKGELG
                     LPGAPGIDGEKGPKGPKGDPGEPGPAGPKGETGEMGLSGLPGADGPKGEKGESASDHL
                     QESLAQIIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGEKGTSGERGPHGLPGPVGP
                     PGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEP
                     GPPGLDQPCPVGPDGLPVPGCWHK"
     exon            469..535
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            536..580
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            581..588
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            589..615
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            616..642
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            643..669
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            670..696
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            697..813
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            814..849
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            850..876
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            877..903
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            904..957
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1020
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1065
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1143
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1197
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1198..1242
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1243..1332
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1395
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1452
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1453..1479
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1542
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1596
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1623
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1624..1677
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1764
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..1803
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..5665
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5639..5644
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /note="hexamer: AATAAA"
     regulatory      5645..5650
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /note="hexamer: AACAAA"
     regulatory      5649..5654
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /note="hexamer: AACAAA"
     polyA_site      5659
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
     polyA_site      5662
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
                     /note="major polyA site"
     polyA_site      5665
                     /gene="Col23a1"
                     /gene_synonym="2810458L13Rik"
ORIGIN      
        1 gtccggccgc tcctcccctg ggtgggtccc cgcgcctttt ctggcggggt ctatttgcat
       61 agaaggaact gcccgcagtg gccgctgagt ctgagcgggc ggctaggggg gcgtgcgcga
      121 tccgcggcca cccggacgcg gagccccgca gccgccgacc tggagccgcc ccgggccgca
      181 gcgccgacgc agagccggcg ggtcgccatg ggcgcgggcg agcgcgcggc gggcggagga
      241 ggcgcgcagg accccggagc gggctgcggg tcgcgggcgc tgagcgcgct gtgcctgctg
      301 ctgtcggtgg gctctgcggc cgcctgtctc ctgttgggag cccaggcggc cgccctgcat
      361 ggccgagtgg cggcgctgga gcaggagcgc gagctgttgc ggcatgcggg gccgtccgga
      421 gccctggccg cctgggccga aacgcacctg gagcgcctgt tacgggagaa gttggatgga
      481 gtcgccaagc tcaggacagt tcgagaagcc ccatctgagt gcatctgtcc ccctggtccc
      541 cctggacggc gtggcaagcc tggacgaaga ggcgaccctg gtcctccagg gcaatcagga
      601 cgagatggct acccgggacc tctaggtctg gacggcaagc ccggacttcc aggccccaaa
      661 ggggaaaagg gtacaccggg agactttggc ccgcggggag cccaagggca agatggagtt
      721 gcaggaccac cggggcctcc tggaccacct ggggcccggg gccctcctgg tgacactggg
      781 aaagatggcc cccgaggagc gcaaggccca gcgggtccca gaggagagcc cggacaagat
      841 ggcgagatgg gccccaaagg acctccagga cccaagggag aacctggcat tcctgggaag
      901 aagggggatg atgggatggc caaccagcca ggactccctg gacccccagg gcccaagggt
      961 gagccagggg atgtggggcc ccgaggagag aatggagtgg acggcattcc tggactaaag
     1021 ggggagcccg gtcacccagg cgtggatgga gccacagggc cccggggtgc cccgggcctc
     1081 aagggagaac aaggtgacac agtggtaatc gactatgacg gcaggatctt agatgcccta
     1141 aagggtcccc ctggaccaca gggagctcct gggccaccag ggatccctgg agccaagggt
     1201 gaactcggat tgcctggtgc tccaggaatc gatggagaga agggtcccaa aggaccaaaa
     1261 ggagacccgg gagagcctgg accagctggg cccaaagggg aaacaggaga gatgggcctg
     1321 tcaggtcttc cgggtgctga tggtcccaag ggagaaaagg gagagtcggc gtctgaccat
     1381 ctacaagaga gcctggccca gatcatagtg gaaccagggc cccctggtcc tcctggtccc
     1441 cctggcccca tgggccttca ggggatccaa ggtcccaagg gcctggatgg agccaaggga
     1501 gaaaagggta catcgggtga gagaggccct cacggcctgc ctggaccagt tggcccacca
     1561 ggccttattg ggttgccagg aaccaaagga gagaagggca gacctggaga accaggactc
     1621 gatgggttcc ctggacccag gggagagaag ggtgaccgaa gtgaacgtgg agagaagggg
     1681 gagcgaggag ttcctggccg gaaaggcgtg aagggccaga agggagagcc gggcccacca
     1741 ggccttgacc agccatgtcc tgtgggcccc gatgggttgc ctgtgcctgg ttgctggcat
     1801 aagtgatcct cagacataac ccctgacctg tacagatccg tttggatgtt ttgaactcat
     1861 gtaaaaacaa aacagtaata tattgaactt ctttatggga tgcgccaact gtggccatgt
     1921 aacatttgca agtgtgccaa ccagcccctg gacaatctgc acaggaagcc agcaggaatg
     1981 cggacaggct gctctgagga aacttctgtt caaaggccct gggtagggcc tggctttccc
     2041 agggaagatg acgagggtga aaacgcctgg ctcaggtgag gctggacaga ctccaggttg
     2101 ggctcataat cacctgatta gcagagactt gcaacaactg tttcctgaaa ccccactgcc
     2161 ccagcttctc actgtccaat agcaccccct tggacaactg ctgtagcctc ttgcttcggg
     2221 actgtgccgt aggcagctgc actggggccc tatgttcaac agggccagca aagattccta
     2281 gagtccagca cttggggaga aggcaatggg aagaacccga agagggcctt gctccaccca
     2341 agttcagcac gcttccagaa gccaccctga cacgggagct tgtattctcg gaccttggga
     2401 aacagcaggc tctgtggata cctcagtgta aagccagctt ccgacagccc agtgaaccct
     2461 aatggtaaga tgaagagacc catacctact acttactact tccagtctcc ttaccgcctc
     2521 tcccagagca ggaactggaa aggactttgt cagcctggag gagacaggcc tcttgttcag
     2581 aacttgtgtc tcaagtctcc cacctagacc tctggtcagc ctgacaaaaa caggcctcct
     2641 tagtaaatgg tacggacacc atgaacctga aggctgatcc cccagcaagc ctgagcaaaa
     2701 cacctgtgac agaaacccct gccctctctg ggggggattg gggcttgaac acttctaatg
     2761 aaggttccta gctcctgctc cattcatggc ttcacagccc tcctcatgta aaggcgccat
     2821 gagtaataaa ccacaaatgt gtgtctggtg tgcctgtcgc ttacagactt ccctggtcac
     2881 ctctgggtga gttttattcc gatggttact agctgaagaa gcaaaggggc tctccttggg
     2941 ggtcagaacc ttcctctaaa tcaggggata tattcagggt aggagataag aagatacagg
     3001 ctcaagatct gaacccacac atgccagcag aatcctggga ctggccacat cctgtcactg
     3061 agtcctctgt atcccctttt gttatgctca gcaaagacac cccaaatttg ttgcctcaaa
     3121 atgtccattc tctcagttct aagggctcag gggcttgcct gaataggcct caagtggatt
     3181 ccccctcatc tgtctgtcag ctaggatcca atgacaatga cacctaccaa cctgtgactt
     3241 ttctgcatgg cctggacttc ctcacagcat ggcagcagga ttcctagaaa gctgtgtcac
     3301 ctcatatgac caagccttca gagtcacatg ctgccacttc ctgccagagc cagaaattta
     3361 ccccacttga attagaagac agacccacct ctcaatgagg aaagtatcaa cgtcatgttt
     3421 aaatgagaaa atatgggaga gtacatttcg ttgtagccct caaaaacaaa ataaaataaa
     3481 attagctctc ttgtagccca ggctagcact gaactcacta tgtagttcag gatgacctta
     3541 aagttctggc cctctactcc ttgctctatc tgctccagtt acagttgtgc accactgtgc
     3601 ctgacttcta cagtgctggg attcaaacct aaggctttat gcctgttaac ataagcactt
     3661 aaccaaaaaa gctacaatct tagcccttgt tacggcatct taaataacac cactcatctg
     3721 tagcatgaga cagtaatgct caaaattcag gtgtggttca gtaagattca gctctgtgga
     3781 atatacacag agagcctagg acagatcaga cacctcactg tacctgtggc tggctgtcct
     3841 cgctctatct gctccaagac caaatagtaa tcacggtcct gcagagtggg cccatgtctc
     3901 cccctaactt gtccttacag caaactgaag aaagatgccc aacaaatgtg cccattttca
     3961 tagatgacaa aaccaagctc tttccctgtg tgtagaaaag acaggagcgt caatgacagt
     4021 gtctctgtcc ccttcctcca agggcagaga tccaaggagg gccacactcc ccagactgta
     4081 cacatgcatt ccttgctaag cagaggccca gccacacaca gctgatgtca agtccctacc
     4141 tctgtccccc tgaggagctg gcaaaaagca gcagaccatg ttctctgcca cactgggtca
     4201 actaggaaac cagataaaag aaaaagaaaa agaaaacaga tgtagtggac caagatgact
     4261 aaggtggctc actggtaaca atgcctgctt tggagatgtg acatagcctc ccaagcccac
     4321 cacagcctac agtcaacaaa gcactcctcc ttcatcctaa gaacaacatc gttagggctg
     4381 caggggtagg tgtcactgtg tccattttac atataggaaa tctgaggctc acagtgcata
     4441 gttatctgct tagagataca cagacaggcg agagtgacag gcttgggact gaacccgtgc
     4501 tctcggaggt cccctaattt ttcttcaggg ttgtttggca acatatggaa tctgctaggc
     4561 agacccctga cgatgggtgg acagcacgca gagctttcta gaggctgacg ccccaaactc
     4621 tccctttcac ctcaggctgc cctgggccat tcttggccca ttactgcccc cgtgtggact
     4681 cataccttgt atccttgcaa atggacatgc agagccatgg agtgtcctgt gccagcctga
     4741 agtgaggaca gagagaatga gttgttcaag gtcccaagtg agacgctggg gagtgccctg
     4801 cctcaacaat gaggctcaag gactgagagg aggccttggt tctccctacc aagaaggcca
     4861 gttctctttg taattatttg taagtcaaat aattctggaa gggaggtatc tgtttattga
     4921 gtccttgact atcctgtgtt ccatgccgct aaagaaacca acgagatgac tgtccccatg
     4981 gacagatggc tctgaggctt gagagaagcg accttactag attccctgtc cttaaagctt
     5041 tgagttgtca caggattggg ggacactcct ggcattcaga agacagtcga ggttagcata
     5101 cacctgaaat ccaggacact ggacacgccc agtagtgaag ctgctcactg tgaatgccag
     5161 ctgaggaaac cctgctctgg attcaagggt tgggcagggg aatgattgct tgttggttga
     5221 gacagggtct caatacataa cttaggctgg tcccaaagtt gcagctctgc ctcagcttcc
     5281 caagtgctgg gattacaggc ttgcaccacc atgcccccca ctacatccaa gtcttgttca
     5341 gtcccttcct cctttcagcc tgtgccttct tggcctccag ggttgccttg aaaggacaga
     5401 tgccagaaaa tggagagagg atgggaccaa ggacaggaag gataggcctt ttctgagcag
     5461 gaagatggac ttttaggtag gtttatggtt aaaaacatga aataccgctc agttggggaa
     5521 gatggaaggg ctctgtgact gggttttggt gacaagatgc aacattgaga atgtactaat
     5581 gccactgaat tgtatgtacc cttcaaaatt gcttgttttt ttatgtatat tttaccacaa
     5641 taaaaacaaa caaaaaccac aagaa
//
