LOCUS       NM_198006               3862 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus cytochrome C oxidase assembly factor 5 (Coa5), mRNA.
ACCESSION   NM_198006 NM_175395
VERSION     NM_198006.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3862)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3862)
  AUTHORS   Jett,K.A., Baker,Z.N., Hossain,A., Boulet,A., Cobine,P.A.,
            Ghosh,S., Ng,P., Yilmaz,O., Barreto,K., DeCoteau,J., Mochoruk,K.,
            Ioannou,G.N., Savard,C., Yuan,S., Abdalla,O.H., Lowden,C.,
            Kim,B.E., Cheng,H.M., Battersby,B.J., Gohil,V.M. and Leary,S.C.
  TITLE     Mitochondrial dysfunction reactivates alpha-fetoprotein expression
            that drives copper-dependent immunosuppression in mitochondrial
            disease models
  JOURNAL   J Clin Invest 133 (1), e154684 (2023)
   PUBMED   36301669
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3862)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3862)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   5  (bases 1 to 3862)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY779699.1, AK166651.1, CN531814.1, AA616104.1 and BQ176168.1.
            
            On Jun 16, 2010 this sequence version replaced NM_198006.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK166651.1, SRR1660817.88800.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-71                BY779699.1         1-71
            72-754              AK166651.1         2-684
            755-1448            CN531814.1         29-722
            1449-2529           AK166651.1         1379-2459
            2530-2958           AA616104.1         161-589
            2959-3855           AK166651.1         2888-3784
            3856-3862           BQ176168.1         20-26               c
FEATURES             Location/Qualifiers
     source          1..3862
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 15.46 cM"
     gene            1..3862
                     /gene="Coa5"
                     /gene_synonym="1700001A24Rik; 6330578E17Rik; Pet191"
                     /note="cytochrome C oxidase assembly factor 5"
                     /db_xref="GeneID:76178"
                     /db_xref="MGI:MGI:1923428"
     exon            1..235
                     /gene="Coa5"
                     /gene_synonym="1700001A24Rik; 6330578E17Rik; Pet191"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..361
                     /gene="Coa5"
                     /gene_synonym="1700001A24Rik; 6330578E17Rik; Pet191"
                     /codon_start=1
                     /product="cytochrome c oxidase assembly factor 5"
                     /protein_id="NP_932123.3"
                     /db_xref="CCDS:CCDS35541.1"
                     /db_xref="GeneID:76178"
                     /db_xref="MGI:MGI:1923428"
                     /translation="MPRYYEDKPEGGACAGVKEDLGACLLQSACVLQEGKSPRQCLKE
                     GNCRALQYSFFECKRSMLDARSRFRGRKGY"
     exon            236..319
                     /gene="Coa5"
                     /gene_synonym="1700001A24Rik; 6330578E17Rik; Pet191"
                     /inference="alignment:Splign:2.1.0"
     exon            320..3862
                     /gene="Coa5"
                     /gene_synonym="1700001A24Rik; 6330578E17Rik; Pet191"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3838..3843
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Coa5"
                     /gene_synonym="1700001A24Rik; 6330578E17Rik; Pet191"
                     /note="hexamer: AATAAA"
     polyA_site      3859
                     /gene="Coa5"
                     /gene_synonym="1700001A24Rik; 6330578E17Rik; Pet191"
                     /note="major polyA site"
ORIGIN      
        1 actcctggcg gaagttgttg agactttctc ccaccctcgc cggtagcttg ccagtgggcg
       61 tgtcccacgc ccttccgggc cgtgcggggt gaccgagggc cgtgatccag tgtggtgagg
      121 gcggtgggtc cccgccatgc cccggtatta tgaggacaag ccggagggcg gcgcgtgtgc
      181 gggcgtgaag gaggatctgg gtgcatgtct gctgcagtct gcctgtgtgc tccaggaagg
      241 aaaatcccca cggcagtgtt tgaaggaagg caactgtaga gctttgcagt attccttttt
      301 tgaatgtaaa agatcaatgc tggatgccag atcaagattc agagggagaa aaggatattg
      361 ataacatgct gaacgcaaga tgaaagtcac ccaggatttt ccatggtcct taacagaaag
      421 gaaccaaacg ggaagcacag cagctgccgc atctcttcca cctctgggcc aggtgttcct
      481 cccaaggaca ccagagaaaa tggatcagtg ctgtttctga atgagtctgc tggctgaagt
      541 catttataga agatccatgg gactaaacaa ctatgggcta agaatgtgtc tggggaatta
      601 cctaatgaag agattatgtt caaggatgac tcttcgatca gattacacag tgtgtgaatt
      661 caggaggcca tgatgagatt ggcatagata gtggctcctc caactctttt ttctgtttct
      721 tggtttcaat tttaggccaa ccccctcctc ataaaggggt gaaatcagcc atagaccaca
      781 tcctcaagat atgggtgggc tccaaaaagg agagcatagg ctggcccaca agtcacaccc
      841 tgctgaagga cgctgctcct tcctgggtca tatgcttggt gatcttggct agatcctggt
      901 cgcatgtact gtgctgacac catgcacaat cacataagat aagttatggg cctcatccct
      961 aaacactgga atgcagcaaa tggacacaac agatgttcac tctagataac aaatgtcaat
     1021 gacatgaagt ggctggaaaa gtttagaatc cttaacatat tattttgacc acttaacaca
     1081 gtagaaagcc atcagggcac taaatcttca gtgtgattct tgccattgaa cagagtggca
     1141 attctatatt gttctgtagt tcactggggc taaagcagtc aaggactgga agttcacttg
     1201 ctattttaaa agtttttgaa gctatgagga ttccctaggg tgtcactgag gtctgctcta
     1261 tgtactgccc ccactgggag taggaggtac tgcacccttg tgctctgtgt actgccccca
     1321 ctgggagtag gaggtactgc acccttgtgc tctgtgtact gcccccactg ggagtgggag
     1381 tattgcaccc ttcagtcctg ccacctatgt cccaagcttg gtgtctgtgt gcagtgtgga
     1441 ggagtgcaca ttctgcatgc taggaagctc gaccattgag ccacaccttc cactagtgct
     1501 tcagtttcaa cagagagtga aatgtgtttg tatgaaatgc ctccatttga gtagatagag
     1561 ctttatttgg aaaaagtcac atgtctcata attggacttt gacttagaca accccatgga
     1621 gtttagagtg ttcgtggagc atgctgcagt caccactatc tacttccaga acagtctcat
     1681 cctttccaga aatgtaacca ctggtcagca ctctgccctc tccctctggt ccaggtctat
     1741 tagatgagtg gaactatgta gtcctgtctt ttctgagtcc tgttaccaaa ttcgacaggt
     1801 ttattggcat gtagcatcag tctgcagtgt agttctgctg agtagcatcc acagtagaca
     1861 gacactgtgt atttctccat cgagcagatg agctctgagc tgtttctact ttggggcttt
     1921 tgactaatgc tatgaacgtt tcatttaata catgccttag agttgaactc caaggtcgta
     1981 tcatgacggc ctcaattata ttttctacag tgattttacc acatttcatg ctgtcatggg
     2041 atctaggctc cagcacccct gactttcaca actgctcata ttgctgacag ccattctgct
     2101 tgtgataaag aggcatctat tgggatcttg gttgcatttc tctagtgtct aataacctga
     2161 gcagtttttc gtgtgttcat tggctctcta tgctgccttt gcagagtgtt ttctagtctg
     2221 cagtctggct tccagttggg ttatctgttt attttcctat aagatttttt atttactgtt
     2281 ggctcaagtc tcttaaagat taattggcat ttttttctca acgtgtttgt ccttttcaat
     2341 ctcttgctac tctatatagc acagtcttta tttttataca ttcccttatg tggcttagcc
     2401 caggctggcc gggaatcccc aaagcgcgag cattttcagc gctgcacttc ccagaaagca
     2461 cacaccgctg ctcttgacta gagcagtttt catattggaa aatgacaatg tcttttttct
     2521 ttcactctaa gaaaccattc ctaacccaaa cttccagaag cttataaatt ttacctctta
     2581 cctgtaggcc tgtgctctca aaattatttt acacaccttt attcatgacc atatttgaaa
     2641 ttagttaaat agaaataata cattttagta tggctaagta tgtagctccg tatatattgt
     2701 gttcagcaca ttcacagtgc agtacagtac agtctgcctg ccgcactgtt ctgcatccac
     2761 ctcaggaaat gcaagtgtgc ccatctgagg actcccagcc actgccaggt cgcccgccct
     2821 gccctgtcct tggcatactc tctcctcatg gtaaccacca ttctctttcc tgtttctgaa
     2881 tttgagtacc ctaagtgcct ggtatatgtg gactctttgt tgtgtgcatg cacttgtgtg
     2941 tgtgtgtgtg tgtgtgtgtg tgagagagag agagagagtg tgtgtgtgtg tgtgtgtgcc
     3001 tccagcgcgg aataccatga aggttcatat catatatcgg tttccttcct ttgtaaggac
     3061 aaatggtatt gtagtatatg ttgtatgcat attgtatgta tcttgttacc tactcatcca
     3121 gccgtgggta cctcggttgt tcccaccctg gagctcctga ctatgctgtg aacgtgtata
     3181 tacaaatacc cctaggaccc gctttcagtc ttaacataca tgtagcagat tgtatgtcat
     3241 agggtacttc tgtttttatt agtaggcatt gccatagttt ccatatcagc cacactattc
     3301 tatgttctgt ccgcagtgca cagagattag aactgcctat gtccttgtga cttgtatgcc
     3361 attctagaag tcgttaagat ccaccagtgc ttctgcttcc tagttccctg actgctggtg
     3421 tgttctagat gcttggtggc tttctttata tagcgtttga agaaattgtt ttaggtctcc
     3481 tctgcccgtt aatagttgac tctggttgaa tttttggtca tcacatctac aaaagcattg
     3541 attccaaggg agctgactgt agcttgccct gggaatttta gttttagttc ttagctttgc
     3601 cctttgatgc attttgagtt aatctttgtg tgtggtggaa gctctgactt tctactctcc
     3661 acatgtgcat atctagcttt gcacaatgcc ctttggaggg aaaacatggc gccatgcatg
     3721 gtggggccgg ttttgagccc agtctctcct gactctgtct gccttcatgc caacgccact
     3781 gctttgatta ctggagaatt actatcaaaa tttgaaatca gaaagtgttt gttctaaaat
     3841 aaaaatttga atctgaaaac at
//
