LOCUS       NM_172851              10141 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus contactin associated protein-like 5B (Cntnap5b), mRNA.
ACCESSION   NM_172851
VERSION     NM_172851.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10141)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 10141)
  AUTHORS   Platt,R.J., Zhou,Y., Slaymaker,I.M., Shetty,A.S., Weisbach,N.R.,
            Kim,J.A., Sharma,J., Desai,M., Sood,S., Kempton,H.R.,
            Crabtree,G.R., Feng,G. and Zhang,F.
  TITLE     Chd8 Mutation Leads to Autistic-like Behaviors and Impaired
            Striatal Circuits
  JOURNAL   Cell Rep 19 (2), 335-350 (2017)
   PUBMED   28402856
REFERENCE   3  (bases 1 to 10141)
  AUTHORS   Weichenhan,D., Traut,W., Gongrich,C., Himmelbauer,H., Busch,L.,
            Monyer,H. and Winking,H.
  TITLE     A mouse translocation associated with Caspr5-2 disruption and
            perinatal lethality
  JOURNAL   Mamm Genome 19 (10-12), 675-686 (2008)
   PUBMED   18949514
  REMARK    GeneRIF: Caspr5-2 disruption leads to dysfunction at the cellular
            level rather than at the level of organ development.
REFERENCE   4  (bases 1 to 10141)
  AUTHORS   Traut,W., Weichenhan,D., Himmelbauer,H. and Winking,H.
  TITLE     New members of the neurexin superfamily: multiple rodent homologues
            of the human CASPR5 gene
  JOURNAL   Mamm Genome 17 (7), 723-731 (2006)
   PUBMED   16845472
  REMARK    GeneRIF: the three Caspr5 genes are located on chromosomes 1 & 17;
            all three paralogs are expressed; common expression is found in
            brain tissue but different expression patterns are seen in other
            organs during fetal development and & in the adult stage
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158402.6, AC157363.6, AC102217.9, AC135080.2, AC163496.4 and
            AC161355.3.
            
            On Jun 20, 2019 this sequence version replaced NM_172851.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BN000866.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN01164131,
                                           SAMN01164132 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-446               AC158402.6         102676-103121       c
            447-551             AC157363.6         66305-66409
            552-745             AC157363.6         92854-93047
            746-893             AC157363.6         176304-176451
            894-1097            AC157363.6         197710-197913
            1098-1282           AC157363.6         201692-201876
            1283-1423           AC102217.9         55316-55456         c
            1424-1688           AC102217.9         11752-12016         c
            1689-1838           AC135080.2         28727-28876
            1839-2010           AC135080.2         32757-32928
            2011-2117           AC135080.2         82356-82462
            2118-2237           AC135080.2         123748-123867
            2238-2438           AC135080.2         143050-143250
            2439-2556           AC163496.4         42680-42797         c
            2557-2684           AC163496.4         31567-31694         c
            2685-2855           AC163496.4         31223-31393         c
            2856-3074           AC163496.4         22182-22400         c
            3075-3314           AC163496.4         17831-18070         c
            3315-3539           AC163496.4         10760-10984         c
            3540-3670           AC161355.3         107861-107991
            3671-3755           AC161355.3         122979-123063
            3756-3974           AC161355.3         154503-154721
            3975-4046           AC161355.3         158050-158121
            4047-10141          AC161355.3         160650-166744
FEATURES             Location/Qualifiers
     source          1..10141
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 48.19 cM"
     gene            1..10141
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /note="contactin associated protein-like 5B"
                     /db_xref="GeneID:241175"
                     /db_xref="MGI:MGI:3664583"
     exon            1..446
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             365..4243
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /note="contactin-associated protein like 5-2; cell
                     recognition molecule Caspr5b; cell recognition molecule
                     Caspr5-2; contactin-associated protein-like 5b"
                     /codon_start=1
                     /product="contactin-associated protein like 5-2 precursor"
                     /protein_id="NP_766439.2"
                     /db_xref="CCDS:CCDS35682.1"
                     /db_xref="GeneID:241175"
                     /db_xref="MGI:MGI:3664583"
                     /translation="MDSVPRLTSILTLVLSGLWHVGLTATNYNCDDPLASFLSPKAFS
                     SSSDLTGSSSSAQLNGRMGTGGWSPENSSAHQWLQLDLGNRVEITAVATQGRYGSSDW
                     VTSYCLIFSDTGHNWQQYKQGDSIWTFIGNMNANSVVHHKLLHAVRARFVRFVPLEWN
                     PNGKIGMRVEVYGCFYKSDVADFDGRSSLLYRFNQKTMSTLKDVISLKFKSMQGDGVL
                     FHGEGQRGDHITLELQNGRLALYLNLDDSKARLSSITPSAILGSLLDDQHWHSVLLER
                     VGKQANFTVDRNTQHFRTNGDTDALDIDYELSFGGIPVPSKPGTFLKKNFQGCIENLY
                     YNGVNIIDLAKRRKHQIYSGNVTFSCSEPQIVPITFVNSRSSYLLLPGTPQIDGLSVS
                     FQFRTWNEDGLLLSTELSEGSGTLLLILEGGTLRLLIKNVAGHGTESLTGRSLNNGQW
                     HSVNINARRNRVTLTLDNDPASPALETPWLQIYSGYSYYFGGCPDNLTDSQCLNPIKA
                     FQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCFPNYCEHGGHCTQTWT
                     NFYCNCSNTGYTGATCHDSIYEQSCEVYRHRGNTAGYFYVDSDGSGPLRPLQVYCNVT
                     EDKIWMTVQHNNTELTWIQGSNTEKPYVMNLNYGGSMEQLEALIDGSEHCEQEVTYYC
                     RRSHLLNTPDGAPFAWWTGRSNERHPYWGGYFPGDQKCGCGLEESCLEMSNDTGFLSF
                     KDHLPVTQIIISDTNRSNSEAAWRIGPLRCYGDRHFWNAVSFSTEAAYLHIPTFHAEF
                     SADISFFFKTTALSGVFLENLGVKNFLRLEMSSPSEVIFAIDVGNGPMELLVQSPYPL
                     NDNQWHYIQAERNIKETLLHVDNLPKSMRMASEEGHFLLQLNSQLFVGGTSSRQKGFL
                     GCIRSLHLNGQKVDLEERAKITSGVRPGCAGHCNSYGRNCQNGGKCVEKHIGYTCDCT
                     NSPYEGPFCKKEISALFYSGTSVTYMFQEPYPVTKNTSLSSSAIYKDTAPSKEAITLS
                     FMTAQAPTLLLYLNFSSQNFLAILLSRNGSLQIQYRLSKEESHVFTISTENLANRRVH
                     QVKMSRDGPELSIQMDQQLFSYNFPPEVEFQTVRSLILGKVTETLGLDPEVAKANTLG
                     FVGCLSSVQYNHIAPLKAALRHASISPVTVQGTLTESSCDSMIDSDVTGVTTVYSPSV
                     PFGKTDEHEPLTNTIQSDSAFIGGVIAIVTFITFCVLGIMVHFLYQQKQSHRTNQMKE
                     KEYPDNLDSSFRNDIDLQNTAIECKREYFI"
     exon            447..551
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            552..745
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            746..893
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            894..1097
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1282
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1423
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1688
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1689..1838
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..2010
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2011..2117
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2118..2237
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2438
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2439..2556
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2557..2684
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2685..2855
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2856..3074
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3075..3314
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3315..3539
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3540..3670
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3671..3755
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3756..3974
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3975..4046
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     exon            4047..10141
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      4247
                     /gene="Cntnap5b"
                     /gene_synonym="C230078M14Rik; Caspr5-2"
                     /note="major polyA site"
ORIGIN      
        1 gaatctagct cttgcgccgg aacaaagtac tttagactat tggtggagct gtgcgcaaga
       61 tctgaacctt taagaaaggc aatctttaag agaaggcaag caagaaaggc aagcacagaa
      121 agggacagtt gcaggaactg tcgactgcag ctcggagctc cgaggaagct ctgctacggt
      181 ttcagtggag gatctgagaa gcaaaatgga gtgaaggaga agagtgtctg tttaaggggg
      241 ggtgggaggg ggcgaggctg tgcgaaggag tggaaacaga gagtgagaaa agaaaagaaa
      301 gaaaagccaa ggctggtgcc tatgaatttg ggattcaact ggaagaatcg ctcactcggg
      361 ggaaatggat tctgtaccaa gactgaccag cattttgact ttggtgctgt ctggcttgtg
      421 gcacgttgga ttaacagcga caaattacaa ttgtgatgac ccattggcct ctttcctctc
      481 accgaaggct ttctccagtt cctcagatct cactggaagt tccagctcag ctcaactgaa
      541 tgggagaatg ggaactggtg gttggtctcc agaaaattcc agtgcccatc agtggctgca
      601 gttggacctg ggaaacagag tagagattac agcagtggcc acacagggaa gatatgggag
      661 ctctgactgg gtgacaagct attgcctgat attcagcgac acagggcaca actggcaaca
      721 gtacaagcaa ggagacagca tctggacatt tataggaaac atgaatgcta acagtgtagt
      781 tcaccacaag ctactgcacg ctgtgagagc ccgctttgtt cgctttgtgc ccttggaatg
      841 gaatccaaac ggaaagattg gcatgagagt ggaggtctat ggatgcttct acaaatcaga
      901 tgttgctgac tttgatggcc ggagctcact tttgtacagg ttcaatcaga agacaatgag
      961 taccctcaaa gatgtgatct ccctgaaatt caagagcatg caaggagatg gggttctgtt
     1021 ccatggggaa ggacaacgtg gagaccacat caccctagag ctccagaatg gaagactagc
     1081 cctatacctg aacttggatg atagcaaagc ccgcctcagt agtattacac cctcagccat
     1141 tctgggtagc cttctggatg accagcactg gcactcagtt ctcctggagc gtgtgggaaa
     1201 gcaagcaaac ttcactgtgg acaggaacac ccagcacttt cggaccaacg gtgacactga
     1261 tgccctggac atcgactatg agctcagttt tggaggaatt ccagtaccaa gtaaacctgg
     1321 gaccttttta aagaaaaact tccaaggctg tattgaaaac ctttactaca atggagtgaa
     1381 cataattgac ttggctaaaa gacgcaagca tcagatctac tccggcaatg tcaccttttc
     1441 ctgctcagaa ccacaaattg tacctatcac atttgtcaac tccaggagca gttatttgct
     1501 gctacctggc accccccaaa ttgatggtct atcagtgagt ttccagtttc gaacatggaa
     1561 tgaggatggt ctgcttctgt ccacagagct gtctgaaggc tcaggaaccc tgctgctcat
     1621 tctggagggc gggactctga gactcctgat taagaacgtg gcaggacatg gaactgaaag
     1681 cctcacaggc agaagcttga ataatggcca gtggcattct gtcaacatca atgcaaggag
     1741 aaatcgtgtt actctcacac tggataatga tcctgcttct ccagctctgg aaaccccctg
     1801 gctacagata tattctggat atagttacta ctttggaggg tgccctgaca atctcaccga
     1861 ttcccaatgc ttaaatccca ttaaggcttt ccaaggctgc atgaggctca tctttattga
     1921 taaccagccc aaggacctca tttcagttca gcaaggttcc ctggggaatt ttagtgattt
     1981 acacattgat ctgtgtagca tcaaagacag gtgtttcccc aactactgtg aacatggagg
     2041 acactgtact caaacctgga caaacttcta ctgcaactgc agtaatactg gttacacagg
     2101 agccacctgt catgattcca tctatgagca atcctgtgag gtatacagac acagaggaaa
     2161 cacagctggg tacttctatg ttgactctga tgggagcggc ccactgagac cactccaggt
     2221 gtactgcaat gttactgagg acaagatctg gatgacggtt caacacaaca acacagagtt
     2281 gacttggata cagggttcca acactgagaa accctatgtc atgaacttaa attatggtgg
     2341 gagtatggag cagctggagg ctctgattga tggctcagag cactgtgaac aggaggtaac
     2401 atactactgt aggagatcac acctgcttaa cacaccagat ggagccccat ttgcctggtg
     2461 gactgggagg tccaatgaga ggcaccctta ctggggaggt tattttcctg gagaccagaa
     2521 gtgtggatgt ggcctagagg agagctgcct ggagatgtca aacgatactg gttttctttc
     2581 cttcaaagat cacttgcctg taactcagat aattatcagt gataccaaca gatcaaactc
     2641 agaagcagct tggagaattg gccccttgcg ttgctatggt gaccgacact tctggaatgc
     2701 tgtctcattt tctactgaag ctgcttacct ccacattcct accttccatg cagaattcag
     2761 cgctgatatt tccttctttt ttaaaaccac tgctttatct ggcgttttcc tagaaaacct
     2821 tggcgttaaa aacttcctcc gacttgaaat gagctctcct tctgaagtca tattcgccat
     2881 tgatgttggg aatggtccta tggaactcct tgtccagtct ccttatcctc tgaatgacaa
     2941 ccaatggcat tacatccagg ctgagagaaa catcaaggag accttattac atgtagacaa
     3001 ccttccgaag agtatgagga tggcctcaga ggaaggccat tttctgcttc agctgaatag
     3061 ccagttgttt gtagggggga catcatcaag acagaaaggc tttcttggat gcatccgttc
     3121 attacacttg aatgggcaga aagtagacct ggaagagagg gcaaagatca catctggagt
     3181 cagacctggc tgtgcaggtc actgcaacag ctatggaagg aactgccaaa atgggggcaa
     3241 gtgtgtggag aagcatattg gctacacctg tgactgtacc aactcaccat atgaaggacc
     3301 tttctgcaag aaagagattt cagcactttt ttattctggg acctctgtta catacatgtt
     3361 tcaagaacca tacccggtga ccaagaacac aagcctctca tcttcagcta tctacaaaga
     3421 tacagctcca tccaaggaag ccatcacact gagttttatg acagcacaag ctcccaccct
     3481 cttgctctac ctcaatttct cttctcagaa ttttctggct attctgctct ccaggaatgg
     3541 aagtttacag attcaatatc gactaagcaa ggaagaaagt catgtgttca ccatcagcac
     3601 agagaatctt gccaatagaa gagtacacca ggtgaagatg agccgagatg ggccagaact
     3661 ttccattcag atggaccagc aactcttcag ctataacttc cccccagaag tggagttcca
     3721 aacagtgagg tcactcatcc taggcaaagt tacagaaact cttgggttgg atccagaagt
     3781 tgctaaagca aatacactgg gttttgttgg atgcctctct tcagtccaat ataaccatat
     3841 cgcaccattg aaggcagccc tccgccatgc cagcatttct cctgtgactg ttcaagggac
     3901 tttgacagag tccagctgtg actccatgat agactctgat gtgactggag tgactactgt
     3961 ttattctcca tcagttccct ttggaaagac agatgagcat gaaccactca caaatacaat
     4021 ccagagtgac tcagcattca ttggaggtgt catagcaatt gtaacattta tcactttttg
     4081 tgtccttgga atcatggtgc acttcctcta tcagcaaaag cagtcacacc gtaccaatca
     4141 gatgaaggag aaggaatacc cagacaactt ggacagttcc tttagaaatg acattgactt
     4201 gcaaaacaca gccatcgagt gcaaacggga atacttcatc tgaactattg tgtggtcatc
     4261 tggtcctctt ttttgcagag gtttccatct ctttttcttt tctttctttt aatttaggca
     4321 ttctctttct ctcacagacc attcatttct tagaatacat attatccacc aagagcacca
     4381 atctcctcgg cccagctcag gagatcaggt agctgtggat attgtaatct attgacatat
     4441 gtatcattgt aaaaaatgac cactgggaca gggactttac tattttaaac aaggaagaga
     4501 cacatgtgcc cacgtgcaca ttctatgatt gtagtccagt ttctaaactt ctctcttcag
     4561 attctcaggc acttgatctt tccagcttcg aatagacttg agctctgtgg tgtttgcctt
     4621 taacaattgt ccctggtcaa tatcacattt ttaggtatta cggctttaga gaagaaaatg
     4681 gagtgtatgt gtctgacaga gaatgatatt gtcagatcat cttttaaggg atgagtttat
     4741 cagggagcag tttcccaatt aatcaggaaa gtatgaagaa gagaaaatct acccagagaa
     4801 agcaacattt gttcttttaa gttccttctg agagaggaag ggagtgttga gatattaggt
     4861 tacaaagaaa agtttgtaaa gttgataagc tgtgtgagtc taaatcaggt aattccctct
     4921 tgtcatggct taatgagctt aatgacaagg cagaattcat tttcctgcca atagcctttc
     4981 tccactcagg acttagattt ctaggagaac atgactccat taacaggtgg ggagctgagt
     5041 tgagagaggc tataggtctg catgggatat ataacagcag ctccccatag caccttggag
     5101 aacaaaagga atgtagttgt agagtcccag ttataaggac acacacctgg tagacccaag
     5161 gcagagggaa actcttcttg cctgctagat tttgtggcat tcggaaagaa acaagagatg
     5221 tttaattttg ttaggttaat gtccatacta taagtagccc cctgactcaa ttcattattt
     5281 ttttccatag aattttagta ctttctaata ctaagtgaat gaatagtgaa catctatttt
     5341 gctcctctct tgctatgcta ttttgaggca tgaataccag gaggtttcaa gaaagatatg
     5401 atgaagtagc tgttcctgta ccttgccact tcccttctcc acattactag aacatgttag
     5461 ctatgatctt tcaaagattt tcctaagaaa agaaatatac atgtatgtgt atagtggtag
     5521 tatacacaga attcgaataa aagtctaact tgtttctatg aaaaggctta ggccaatcta
     5581 actgagattg taggaaaaca ggaaaaaata agggaaaaaa gaaaatatca tggaaattta
     5641 atctaatcaa gaaatggtgc agacctttaa tcccagcact tggaaggcag aagcaggtgg
     5701 attcctgagt tcgaggccag cctggtctac aaagtgagtc ccaggacagc cagggctata
     5761 cagagaaacc ctgtctcaaa aaaacaaaac aaaacaaaaa aacaaaaaaa aacaaaaaaa
     5821 aaacaaaaaa aaaaacaaaa acaaaaacaa acaaaaaaag aaatgtctgg taaaggaaaa
     5881 atgtacaggt tagctaccag gatttacatt atagaacaca tgtggtgact tcattccaac
     5941 aacagagata tttcccagga ggcaagggac tagatgttat tcggggcagt gtggttacct
     6001 ctatatgaga ggatttcatg ggagtcctta gtttgtgaag cacatcatgt tttccagtct
     6061 gtacctgcac caatgtaaac ataagtatct catgcagttg actgatgtgc ctaagtaaga
     6121 gtaatgcatt tcagggtgtg ggttctattg gtggcaaagc acattcaaag aagcatcttg
     6181 aatttgctgc aggtgtgtaa tattgatcat ttcatggtaa caatagtttt aactgtgccg
     6241 ttggaccacc tccaataaat gaatagggag aaactatcta agcatttcag ttcccaagaa
     6301 atactagaag caagatcctg accaatttcc attgcatgga agacctgatt tgcaacacat
     6361 atacttgaga gacaataggc cttccttctt agtcagtatc ctacctctta ctgtccatca
     6421 ctgctctgga caaggaggtt cttagtaaag agcttgctag cttaatccag tttcccagct
     6481 gtagctttta ttcctttaca aagctacaga gggaaggatg gagtgtggca cacaccacaa
     6541 atatgagata ttgttctaaa tatatgttct ttccttagta ttttatgtta cttctgacat
     6601 accacttctt cttttagaat attaattttt ggtagtgaat ttattttaaa gtaattctaa
     6661 caaatatgcc ctcttacatt tttatatctt tgataataga aatgttcgtc taataaaaca
     6721 atagatatta agagtatatt tctttttcct tctattttcc ttttgttctg tttctacttt
     6781 tgaatgttat atctctaaac aagactttat aattcacatt ttctcttggc tgcatatttc
     6841 tctcacacca gacatgaagg tcatgcgtag tttagcccta agcactgtta gtagtgaaat
     6901 aagaagtaaa aatgagtgtt gcctctaaaa tactttctaa ctgtagtcct tagaagcaag
     6961 cattacattt tgctgacatg atgttgataa atagaattgg tgttacaagc ccactaagtg
     7021 tgttcagttt cctcatcctc taaggtgtac ttacaggtaa tcatgtagga aaattcatga
     7081 agccagtctc tgccctctgc atagcacaca ttttactgga ttcatcctta aataagtagg
     7141 ctgtacagac caggacactg gcatgcaaac aaaatgctga atatgtgcca agttggtgca
     7201 atgtgtgatc tcagggctaa atcataattt tctcacaatg ccacaataca caccaagtga
     7261 aaatgtagta atctgcaccc tcctacactg aatgccatca cagtgaaaag caagagccag
     7321 tgttagcata gtggcaagat ctatttggtt tatccacttt ctcaattgtg ttacagcaac
     7381 agaagtcgac acagaacacc agtgagcaga gagcaagtaa tgtgcacatt aaatatataa
     7441 atcgtttcca gagacttcta gaagacaaca catttctggc taaatctttg aattttgtgt
     7501 catatttatt aattctacca tatgtaattt ctttgtttct cttcttcaaa ctatgtaact
     7561 gcccatgcag gcaaatttct gtacaagaca ataaagcatg tcttggacag agaaagagaa
     7621 aaaggtacct atatcacaca atttctgtaa ctgggttcca cctggtagcc ctggctggtc
     7681 tggtgttcta ttataaatca gccttacctc aaaactcaga gagaattatc tgactctggc
     7741 aaggtgtaga ctatcatctc tccttatata agatgcattt gaaaaatgtt aaacttttta
     7801 tattattgat aaagcatttc aaatgcatgc ctctatatgt ggcagacaca tgtagactgc
     7861 aagcaggaaa gagcagtcta cttccatccc cttctgtgac cacttctttg gtggataatc
     7921 ccttatgcca cagctctctt agatctccct tccagtggtt gatagcctgg aatttttaat
     7981 tctccccact gtgctgcaaa gaaccattag actatagtta gaacaatctc tgagacctat
     8041 cattatttgt ctattgagtt aataatttat tgatgtgctt ctcatctaag caacttcata
     8101 ctaatgtatg atctacatgg ctttttacag ccttgtgttt catacatgtt ctctcaccgt
     8161 atcatatcat ctcaattaga agacttacac tgggagagtg catttataac atccacattg
     8221 tatccgtgga catgggcaca aatctgtgga actattgttt agtttgtttg tctaccaact
     8281 gcttcacttc tttggaattc actagtgcta caatctatca atgttattac aactgcagtc
     8341 tggtaagaga atcatgggca cctatattgt tcttccactt attattctgg aaatgattgc
     8401 ttatgtatgc ttggtcttca actgtcctcc agaccatgtt tcagctaaat aaataagcat
     8461 acaaggttat acctgtatgt ggcaaagaag gataatggaa gagggataca ggcaaatgaa
     8521 aacatgtttc agtttttgaa gaatgattga gtaatcttta attttcttca cacagattgt
     8581 aaatgtgttg tttaaaagac tcagcttatc tgaatcactt ctatacactt ttggacttta
     8641 ttaacatctc tttggcttta ccctgagtct tcctcacatc atttgatttg aatatgtgtt
     8701 tttcttcttt cttatgtttg tgttcacaaa ttctatatag tttatccacc tgaagggaga
     8761 gaatatgcaa cacacacaca cacacacaca cacacacaca cagagacaca gagacagaga
     8821 gagagagaga gagagagaga gagagagaga gagaacctta gcagagcttt ttctcaaata
     8881 ttattcagaa aactaagact atttagacag ccatcacctg aaactctatg aagagtcttc
     8941 atatgatttt cctcagtaga cagtttgcat caaatagcaa attaaaatta gtaggctagt
     9001 cacaaattat tacaaagctg atatgtgcta gtcatagttt cattagcatt atactgtgtc
     9061 atacttcaga tcccagtagt aaatctcaga ggacaaggaa aagacactgg atacatagaa
     9121 taggctacta ttgcctcctt gaattccttc ctcagatgta tattttcatt gtaatctcat
     9181 aggatgaaat gaatggggct ctgtatagat ttacttttac attatactca gccatgtccc
     9241 aaagacatat atgaagtacg aacttaatct cttctctttg aatgagagta tcagtaagta
     9301 caatcttgcc ctgccttaaa tagcattgca aaaaataaat aaataaataa ataaatgaat
     9361 aaatgaataa ataaataaat aaataaataa ataaataaat aaataaataa agtaaatgat
     9421 catacctggc ccaaattagt ttgcttgaat cataagaagg actttgtatt tggtgaagat
     9481 caatgccagt aattttatct tcaacttggg aataaatagg cttctcaata gcctatgttc
     9541 attttaatag acacttccaa ctgccagaga acctatggca ggaaagtaga ataaaaggac
     9601 atggaggcac aggacacatt ctaattatac catataaagt agacaacact tcatatttgg
     9661 ttcatgaaat ttccaaattc caaagacaaa gactgtccat gttcatttga aatgagaaac
     9721 tagagtcttc ctgacatggt caggactttc tttggaagaa tgagagatca gagagatcac
     9781 tttcacaagg taaataacaa agtataaaag acaatttgcc aaatacctaa caggctgtcc
     9841 tttgattaaa gcacaacaga agcaaaaaaa gaccatttat ttcctttggg gttaacatga
     9901 gactacttgt tttttggggt ttgttcctgt aacagaatcc ctagacccat atgatgttgc
     9961 cacattccat gtctgctttg tagaccatgt aatatgtctt aatacactgt atagtgaatg
    10021 ttaaagttag ccttcaattt ctttattttc tatggttttt tgctgtacag aaataagact
    10081 tacacataaa tattgtatat ttaataaaga aagattttgt atcttttgtg tggaatataa
    10141 a
//
