LOCUS       NM_001081129            6367 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus contactin associated protein-like 3 (Cntnap3), mRNA.
ACCESSION   NM_001081129 XM_138666
VERSION     NM_001081129.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6367)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6367)
  AUTHORS   Chen,S., Liu,G., Li,A., Liu,Z., Long,B., Yang,X., Gong,H. and Li,X.
  TITLE     Three-dimensional mapping in multi-samples with large-scale imaging
            and multiplexed post staining
  JOURNAL   Commun Biol 6 (1), 148 (2023)
   PUBMED   36737476
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6367)
  AUTHORS   Cui,W., Gao,N., Dong,Z., Shen,C., Zhang,H., Luo,B., Chen,P.,
            Comoletti,D., Jing,H., Wang,H., Robinson,H., Xiong,W.C. and Mei,L.
  TITLE     In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon
            cluster development
  JOURNAL   Curr Biol 31 (15), 3330-3342 (2021)
   PUBMED   34143959
  REMARK    GeneRIF: In trans neuregulin3-Caspr3 interaction controls DA axonal
            bassoon cluster development.
REFERENCE   4  (bases 1 to 6367)
  AUTHORS   Zhang,Z., Wei,S., Du,H., Su,Z., Wen,Y., Shang,Z., Song,X., Xu,Z.,
            You,Y. and Yang,Z.
  TITLE     Zfhx3 is required for the differentiation of late born D1-type
            medium spiny neurons
  JOURNAL   Exp Neurol 322, 113055 (2019)
   PUBMED   31491374
REFERENCE   5  (bases 1 to 6367)
  AUTHORS   Tong,D.L., Chen,R.G., Lu,Y.L., Li,W.K., Zhang,Y.F., Lin,J.K.,
            He,L.J., Dang,T., Shan,S.F., Xu,X.H., Zhang,Y., Zhang,C., Du,Y.S.,
            Zhou,W.H., Wang,X. and Qiu,Z.
  TITLE     The critical role of ASD-related gene CNTNAP3 in regulating
            synaptic development and social behavior in mice
  JOURNAL   Neurobiol Dis 130, 104486 (2019)
   PUBMED   31150793
  REMARK    GeneRIF: These evidences elucidate the pivotal role of CNTNAP3 in
            synapse development and social behaviors, providing mechanistic
            insights into autism spectrum disorders
REFERENCE   6  (bases 1 to 6367)
  AUTHORS   Hirata,H., Takahashi,A., Shimoda,Y. and Koide,T.
  TITLE     Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early
            Phase of the Accelerated Rotarod Task
  JOURNAL   PLoS One 11 (1), e0147887 (2016)
   PUBMED   26807827
  REMARK    GeneRIF: Our findings suggest that reduced activation of neural
            cells in the dorsal striatum in Caspr3-KO mice leads to a decline
            in motor learning in the accelerated rotarod task.
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6367)
  AUTHORS   Hirata,H., Umemori,J., Yoshioka,H., Koide,T., Watanabe,K. and
            Shimoda,Y.
  TITLE     Cell adhesion molecule contactin-associated protein 3 is expressed
            in the mouse basal ganglia during early postnatal stages
  JOURNAL   J Neurosci Res 94 (1), 74-89 (2016)
   PUBMED   26389685
  REMARK    GeneRIF: The findings of this study suggest that Caspr3 may play an
            important role in basal ganglia development during early postnatal
            stages.
REFERENCE   8  (bases 1 to 6367)
  AUTHORS   Araujo,D.J., Anderson,A.G., Berto,S., Runnels,W., Harper,M.,
            Ammanuel,S., Rieger,M.A., Huang,H.C., Rajkovich,K., Loerwald,K.W.,
            Dekker,J.D., Tucker,H.O., Dougherty,J.D., Gibson,J.R. and
            Konopka,G.
  TITLE     FoxP1 orchestration of ASD-relevant signaling pathways in the
            striatum
  JOURNAL   Genes Dev 29 (20), 2081-2096 (2015)
   PUBMED   26494785
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159190.2, AC101142.9 and AC156576.3.
            
            On Mar 8, 2022 this sequence version replaced NM_001081129.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.59671.1,
                                           SRR9219379.36908.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-230               AC159190.2         121015-121244
            231-341             AC101142.9         169399-169509       c
            342-535             AC101142.9         140304-140497       c
            536-683             AC101142.9         80773-80920         c
            684-887             AC101142.9         75870-76073         c
            888-1072            AC101142.9         74935-75119         c
            1073-1219           AC101142.9         74005-74151         c
            1220-1481           AC101142.9         69409-69670         c
            1482-1622           AC101142.9         66925-67065         c
            1623-1794           AC101142.9         63432-63603         c
            1795-1901           AC101142.9         60496-60602         c
            1902-2021           AC156576.3         4782-4901
            2022-2222           AC156576.3         5414-5614
            2223-2379           AC156576.3         13289-13445
            2380-2507           AC156576.3         15524-15651
            2508-2678           AC156576.3         19151-19321
            2679-2897           AC156576.3         20147-20365
            2898-3137           AC156576.3         25654-25893
            3138-3362           AC156576.3         28913-29137
            3363-3496           AC156576.3         30700-30833
            3497-3584           AC156576.3         31774-31861
            3585-3806           AC156576.3         36535-36756
            3807-3878           AC156576.3         36953-37024
            3879-6367           AC156576.3         38902-41390
FEATURES             Location/Qualifiers
     source          1..6367
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 33.46 cM"
     gene            1..6367
                     /gene="Cntnap3"
                     /note="contactin associated protein-like 3"
                     /db_xref="GeneID:238680"
                     /db_xref="MGI:MGI:3588199"
     exon            1..230
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..4000
                     /gene="Cntnap3"
                     /note="cell recognition molecule Caspr3"
                     /codon_start=1
                     /product="contactin-associated protein-like 3 precursor"
                     /protein_id="NP_001074598.1"
                     /db_xref="CCDS:CCDS36703.1"
                     /db_xref="GeneID:238680"
                     /db_xref="MGI:MGI:3588199"
                     /translation="MARVNGAFLDALLLLLLLSVQTLPLVAAGDPHNCDAPLASSLPQ
                     LSFSSSSQLSSSHGPGFARLNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGG
                     YGSSDWVTSYLLMFSDGGRNWKQYHQEESISGFPGNTNADSVVQYSLQPSFHTRFLRF
                     LPLTWNPKGRIGMRIEVYGCSYKSEVVYFDGQSSLLYKFDNGAIRPVREVISLKFKAM
                     QNSGIIFHGKGQHGTHIVLELNKGKLVVYLNSGDGNLPPVNSIMNFTLGSLLDDRHWH
                     SVLIELHNMHMNFTLDKYMHHVHVNKETSYLDLNFEISFGEILMPGGRFLTFPHKNFH
                     GCLENIYYNGVNIIKLAKKHESQILIKGNVSFTCPQPQTIPVTFLSSGSYLALPSSLR
                     EDKMSLAFQLRTWNKAGHVFFSQVGHGSGSLVLFLKNGKLILNLSEPGQPLQSITTGA
                     VLNDGLWHSVSVSAKGSYLSLLVDGDTAQTLMSVEIHLGDTYYFGGCPNNSSSFGCEH
                     SFGGFQGCLRLISVGDKVVDPIAVQQGVLGSFSDLQIDSCGIIDRCLPSYCEHGSRCT
                     QSWDTFSCDCEGTGYTGTTCHSSIYEQSCEAHRHRGSPSGLYYIDVDGSGPLAPFLVY
                     CNMTADTAWTVVQHGGPDVVTVRGGPEGHMHSATFSYAANAAQLHAVVNVAEHCEQQV
                     DLQCRTSGPSDTGDGTSLSWWVGRSNETYTYWGGSLPNPQKCTCGFEGNCIDSQYHCN
                     CDADRNEWTSDTIVLSHKEHLPVTEMVVTDTGRPYSEAAYTLGPLLCQGDKSFWNSAS
                     FNTEASYLHFPTFRGELTADVHFLFKTTISSGVFMENLGITDFIRIELRAPTEVTFSF
                     DVGNGPCELTIQSPTPFNDNRWHHVRAERNVKGASLQVDQLPQKTQSTPADGHVRLQL
                     NSQLFIGGTASRQKGFLGCIRSLQVNGMALDLEERAVMTPGVEPGCSGHCSSYGHLCR
                     NGGMCQEKHRGIACDCAFSAYDGPLCSYEISAYFETGSSVTYNFQEYSTLSANTSYLA
                     SSLHGDVILSRETITLSFRTTQTPCLLLYVTSFYEEYLSIILANNGSLQVRYKLDRHR
                     NADAFNFDLRNLADGHFHQLTINREEAVVSVEVNQSTKRQVILSSGTEFNAVKSLVLG
                     KVLEPLDADPETQQAAAQGFTGCLSSVRFGLEVPLKAALNQNRARVTIQGSVAAAAHC
                     AEGPGSAERKLSPGPSMDAGHSGSAEDRQPLPNTDRSDPGVIGGITAVVIFILLCVSA
                     IAIRVHQQRRLHQKNESTVSKTEEC"
     exon            231..341
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            342..535
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            536..683
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            684..887
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1072
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..1219
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1481
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1622
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1623..1794
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1901
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1902..2021
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2022..2222
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2223..2379
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2380..2507
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2508..2678
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2679..2897
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2898..3137
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            3138..3362
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            3363..3496
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            3497..3584
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            3585..3806
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            3807..3878
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     exon            3879..6367
                     /gene="Cntnap3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6342..6347
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cntnap3"
                     /note="hexamer: AATAAA"
     polyA_site      6367
                     /gene="Cntnap3"
                     /note="major polyA site"
ORIGIN      
        1 agagcaggga tagcagcctg tgagttgcaa gaggaaagcc ggcaagcagg gagggttgtc
       61 agaagccagg caggacactg aagccaccca agcagctgct gctctcttta tagagtttct
      121 ggagcccaaa gtgatcatgg cacgggtcaa cggagcattc ctggatgcgt tgctgcttct
      181 gctgctgctg tctgttcaga ccctgcccct agtagcagca ggagatccac acaattgtga
      241 tgctccgttg gcttcttctt tgcctcagtt atccttcagc agctcctcac agctgtccag
      301 cagtcatggc cctggctttg caagactaaa tagaagagat ggagctggtg gatggacacc
      361 gcttgtatca aataaatatc agtggctgca gattgacctt ggagaacgaa tggaggtcac
      421 tgctgtggcc acccagggtg gatacgggag ttctgactgg gtgaccagtt acctcctgat
      481 gttcagtgat ggtggaagga actggaaaca gtatcatcaa gaagaaagca tctcgggatt
      541 tccaggaaac acaaatgcag acagtgtggt acaatatagt ctccagcctt ccttccacac
      601 caggttcctg cgcttcctcc ccttaacctg gaaccctaaa ggcaggattg ggatgcggat
      661 agaagtatat gggtgttcat acaaatctga ggtggtttat tttgatggac aaagttctct
      721 gctctacaaa tttgataacg gagccataag accagtaaga gaggttattt ctttgaaatt
      781 taaagccatg cagaacagcg ggattatatt ccatggaaaa ggacaacatg ggacacatat
      841 tgttttggaa ttaaacaaag gaaagcttgt cgtttatctt aattcaggcg atggaaacct
      901 gcctcctgtt aattctatca tgaacttcac cttaggcagc cttctggatg accggcactg
      961 gcactctgta ctcattgagc tccataatat gcatatgaac ttcaccctgg acaaatacat
     1021 gcatcatgtt catgtgaaca aggaaaccag ttacttggat cttaattttg agatcagctt
     1081 tggagaaatc ctgatgcctg gagggcgttt cctgacattc ccacataaaa attttcatgg
     1141 atgtttagaa aatatctatt ataacggagt caatattatt aaattagcca agaaacatga
     1201 atcacaaatc ctaattaagg gaaatgtgtc cttcacatgc ccacaaccac agacaattcc
     1261 agtgactttc ctgagttctg ggagttacct ggctttgcca agtagtttaa gggaagataa
     1321 aatgtccctc gcttttcagc ttcgaacatg gaacaaggca ggacatgtgt tttttagcca
     1381 agtggggcac ggttcaggaa gtttggtcct gtttcttaag aatggaaaac tcatactgaa
     1441 cctctctgag cctggtcaac ccttgcagag catcacaaca ggtgccgtac tgaatgatgg
     1501 gctatggcac tcagtttccg tgtctgctaa gggtagctac ctaagccttc tggtagatgg
     1561 agacactgct cagaccctga tgtctgtgga gattcatttg ggcgacactt actattttgg
     1621 aggttgtccc aacaacagct ctagctttgg atgtgaacat tcttttggag gcttccaggg
     1681 ctgcctgagg ctcatctctg ttggtgacaa agtagtggat cctattgcag tacagcaggg
     1741 agtgctgggc agcttcagtg acctccagat agactcctgt ggcatcatag accggtgttt
     1801 gccaagctac tgtgagcatg ggagtagatg tacccagtca tgggacactt tctcctgtga
     1861 ctgtgaaggc acgggctaca ctggaacaac ctgccattcc tccatctatg aacagtcttg
     1921 tgaagcccac aggcacagag gtagcccttc tggactttac tacattgatg tagatggaag
     1981 tggaccactg gcaccatttc ttgtatactg caatatgaca gcagacacag catggactgt
     2041 tgttcagcat ggaggccccg atgtagtgac agtcagaggt ggtccagaag gacacatgca
     2101 ttctgcaacc ttctcctatg ctgccaatgc agcacagctg catgctgtgg tgaatgttgc
     2161 agagcactgt gagcagcagg tggacctaca atgtaggacc tcagggccct cagatacagg
     2221 agatggaacc tccctgagct ggtgggttgg aagaagcaat gaaacataca cttactgggg
     2281 aggttctctt cctaatcctc aaaagtgtac ttgtggattt gaagggaact gcattgattc
     2341 tcaataccac tgcaactgtg atgctgaccg gaatgaatgg accagtgaca caatagtcct
     2401 gtctcataag gagcacctgc ccgtcactga aatggtggtg acagacacag gccgaccata
     2461 ctctgaagct gcttatacac tggggccttt gctatgccag ggagacaagt cattttggaa
     2521 ctcagcttcc ttcaacaccg aggcttctta ccttcatttc ccaaccttcc gtggagagct
     2581 caccgcagat gtgcacttcc tttttaagac caccatttcc tctggtgtgt tcatggagaa
     2641 cctgggaatc actgacttca tcagaataga gttgcgtgct cccacagaag tgaccttttc
     2701 ttttgatgtt gggaatggac cttgtgagct cactatacag tcaccgactc cctttaatga
     2761 caaccggtgg catcatgtga gagcagaaag gaatgtcaag ggtgcatctc ttcaggtaga
     2821 ccaactccct cagaagacac agtccactcc tgctgatgga catgttcgac tacaactcaa
     2881 cagccagctc ttcattgggg ggacggccag caggcagaag ggcttcctgg gatgtatccg
     2941 gtcccttcag gtgaatggaa tggcactaga cctggaggaa agggctgtaa tgacaccagg
     3001 agtggagcca ggatgttcag gtcactgcag cagctatgga cacctgtgtc gaaatggggg
     3061 aatgtgtcaa gagaaacaca gagggattgc ttgtgactgt gccttctctg cctacgatgg
     3121 gccactgtgc tcatatgaga tttctgcata ttttgaaacg ggttcctcag tgacctataa
     3181 ttttcaagaa tattccaccc tgagtgcaaa caccagctac ctggcttctt cattgcatgg
     3241 ggatgtcata ctgtccagag aaaccatcac gctgagcttc cgaaccacac agacaccatg
     3301 cttattgctt tatgtgacct ctttttatga ggaatacctt tccattatcc tggccaacaa
     3361 tggaagtttg caggtgaggt acaagttgga cagacatcgg aatgcagatg ccttcaactt
     3421 tgaccttaga aacttagcag atggtcactt tcaccagctg acgattaaca gggaagaagc
     3481 agtagtctct gtagaggtta accagagtac aaagaggcaa gtcatcttgt cctcagggac
     3541 tgaattcaat gctgtcaaat cgctcgtatt gggaaaggtt ttagaacccc tggatgctga
     3601 tcctgaaaca cagcaggcag ccgctcaggg cttcacaggc tgcctctctt ctgtgagatt
     3661 tggcctggaa gtcccactga aggctgcact gaatcaaaac cgggctagag tcactattca
     3721 aggcagtgtg gctgctgcag ctcattgtgc agaaggccct ggttctgcag agaggaaact
     3781 gtctccaggg ccctctatgg atgcaggtca ttctggatcc gcagaagata gacagcccct
     3841 tcctaacaca gacaggagtg accctggggt cattggagga ataacagcag ttgtgatatt
     3901 tattttgctc tgtgtgtctg ccatagccat acgggttcat caacagagaa gattacacca
     3961 aaaaaacgag tcaacagttt caaaaactga agagtgctaa gactgctctc aaaagtgaaa
     4021 tatgagttga aacagaagca gtcttctagg tgactatggc tggcctgcct cttggcaatc
     4081 ccattcttcc tgggccaggg agtgtccagt gccagtttac agaggactaa cagtctcaga
     4141 ctccgggagg ctggctccct tcctcagcaa aactctccct cctagcaatt tacaagcaag
     4201 ggagtgtggt cattaatcat ggtggagtag tttccccaga tggaatgctc ttttctaaat
     4261 agggctttaa tttgtgtaac atttacgaat tttagctgag aaactaagta gccgtcaagc
     4321 tatggtcctg cttagaaaat gggacagaac tttcattcag ataaagtcaa acagttgttg
     4381 gttggttggt tttggttatt gttgtttttg tgttgttgtt gtttcctgaa aacttatctg
     4441 ggatctcttt gttgctcttc tgctaacgtg tataaaatag agctaaatag cctgcatctc
     4501 catggttctg gaatgcaggg tcacgtgacc tgtttaaaac aaacaaacaa acaaaaaaga
     4561 cagcaacttt cctgtttgct ggccaataca aagagaggac tggaaatatt tttggtacat
     4621 tgctttttac tagccaactg tttctaatca ttttgataaa tttcaaagtc aaaactggta
     4681 ttgaatgtta caaaatttta atgttggttt ttgtaatgag acaaaaaatt aataggtaac
     4741 aaaatggatg catagtgact agccactaag aaaggatgtt gttttctttg taatttgtaa
     4801 ttataggttt ttataaatta tgatcatgtt ttaaactaaa tttatagcca taaatattgc
     4861 ttcttactca acaacaccca agtcgaatat aatcttgaac ttatttactc ccaacttatt
     4921 tattgaaaga agctgtcagc ttttctttat tattctgtat ttctattttt ctaaaagttg
     4981 ttaccaatat gctttgaatt tctatgacta tactgaatag gtacatcttc tcaatttatt
     5041 agacaaatta gctccagctt aagagccccc aatccttttc caaagctgga attgctttgg
     5101 gcataaatac tgtatatcat cctctctgtc cagttttatg gtgtaaactg aagggcacta
     5161 aatccaagga aagatacact tacatgatct gcattaaaca taccaactgt aatcacaagt
     5221 ttgtgatcac agaaacatat tttcatagat tcttacaatt tgagtatgaa ctaataactt
     5281 aattatgtct cactatggtt tctacacact aaaaccagag gatggaagta atttcatgga
     5341 gacagttgca ggaactaata atgaggcagt gttatctgtt aattgaatga actagtttgt
     5401 accagttata gtaaagtcaa tgatgctaca ttcactagga tccagatact gattgtctgt
     5461 gaaggactaa cgaggttgaa cagctcatcc gtatctggga aagtttgaaa tatcccactt
     5521 caacattagc actcataatg gaatttctat ctcgtttgtg ttatttttga aagaaggaat
     5581 atgaatctcc tctgtctcaa gtctgctcct agtattctca ttttcattga tgtttatgtg
     5641 gagggcggtt ttctatttat gctgtattat tgcatatctg tgtgattata tatattgtaa
     5701 tatgtgggaa acacaacttc ataaataata tatgttctgt gtgttttttc tcatgagcct
     5761 tcttagaatg aagacacagt ctacaaaact atagttacat tttattagcc aatataagca
     5821 ccatgcagtc actataactt ttacagatac atttcttgtc tcacagaaaa ctttagaagc
     5881 tggaatttca cagtgttcaa caagataaat tatcacagcc cactgttcca tactttcagc
     5941 aagacaacaa aactaaatca tcaaattgcc ttgatatgtc atctactaac agtcttccaa
     6001 gatggctttc agattttgcc attttatttg aaaataaatt catttttgag aaataatagg
     6061 gaaactattt taagggaagt tgtataaaat acattcattt ttgaaataaa aaattatttt
     6121 aagggaagtt gtgtaaaaca aattataagg tgatttttcc tagtttgcac aaatgtatac
     6181 aggtaaattc actgtactgg tttatcataa tgtaaatgaa gataaatctt tactaattgc
     6241 tagatcaaaa ctatatgaat gtatatgttt aaagttttgt ctgaaaacaa atgtttaaga
     6301 ataagctaac taaagtctgt tttcagtact tctgctgttg taataaaaat cctaaacatt
     6361 ctttgga
//
