LOCUS       NM_016782               5360 bp    mRNA    linear   ROD 14-MAY-2024
DEFINITION  Mus musculus contactin associated protein-like 1 (Cntnap1), mRNA.
ACCESSION   NM_016782
VERSION     NM_016782.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5360)
  AUTHORS   Chang,C., Sell,L.B., Shi,Q. and Bhat,M.A.
  TITLE     Mouse models of human CNTNAP1-associated congenital hypomyelinating
            neuropathy and genetic restoration of murine neurological deficits
  JOURNAL   Cell Rep 42 (10), 113274 (2023)
   PUBMED   37862170
  REMARK    GeneRIF: Mouse models of human CNTNAP1-associated congenital
            hypomyelinating neuropathy and genetic restoration of murine
            neurological deficits.
REFERENCE   2  (bases 1 to 5360)
  AUTHORS   Oh,H., Lee,S., Oh,Y., Kim,S., Kim,Y.S., Yang,Y., Choi,W., Yoo,Y.E.,
            Cho,H., Lee,S., Yang,E., Koh,W., Won,W., Kim,R., Lee,C.J., Kim,H.,
            Kang,H., Kim,J.Y., Ku,T., Paik,S.B. and Kim,E.
  TITLE     Kv7/KCNQ potassium channels in cortical hyperexcitability and
            juvenile seizure-related death in Ank2-mutant mice
  JOURNAL   Nat Commun 14 (1), 3547 (2023)
   PUBMED   37321992
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5360)
  AUTHORS   Cifuentes-Diaz,C., Canali,G., Garcia,M., Druart,M., Manett,T.,
            Savariradjane,M., Guillaume,C., Le Magueresse,C. and Goutebroze,L.
  TITLE     Differential impacts of Cntnap2 heterozygosity and Cntnap2 null
            homozygosity on axon and myelinated fiber development in mouse
  JOURNAL   Front Neurosci 17, 1100121 (2023)
   PUBMED   36793543
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5360)
  AUTHORS   Pijuan,I., Balducci,E., Soto-Sanchez,C., Fernandez,E.,
            Barallobre,M.J. and Arbones,M.L.
  TITLE     Impaired macroglial development and axonal conductivity contributes
            to the neuropathology of DYRK1A-related intellectual disability
            syndrome
  JOURNAL   Sci Rep 12 (1), 19912 (2022)
   PUBMED   36402907
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5360)
  AUTHORS   Chang,K.J., Agrawal,I., Vainshtein,A., Ho,W.Y., Xin,W.,
            Tucker-Kellogg,G., Susuki,K., Peles,E., Ling,S.C. and Chan,J.R.
  TITLE     TDP-43 maximizes nerve conduction velocity by repressing a cryptic
            exon for paranodal junction assembly in Schwann cells
  JOURNAL   Elife 10, e64456 (2021)
   PUBMED   33689679
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5360)
  AUTHORS   Seyfried,T.N., Weber,E.J. and Daniel,W.L.
  TITLE     Absence of brain ganglioside abnormalities in shambling mutant mice
  JOURNAL   J Neurochem 27 (1), 295-296 (1976)
   PUBMED   956836
REFERENCE   7  (bases 1 to 5360)
  AUTHORS   Green,E.L.
  TITLE     Fitness of heterozygotes of deleterious recessive mutations in the
            mouse
  JOURNAL   Mutat Res 12 (3), 281-289 (1971)
   PUBMED   5563943
REFERENCE   8  (bases 1 to 5360)
  AUTHORS   Green,E.L.
  TITLE     Linkage of shambling with sex in linkage group VII of the mouse
  JOURNAL   J Hered 59 (1), 59 (1968)
   PUBMED   5661165
REFERENCE   9  (bases 1 to 5360)
  AUTHORS   Meier,H.
  TITLE     Pathological findings in shambling, a hereditary neuropathy of mice
  JOURNAL   J Neuropathol Exp Neurol 26 (4), 620-633 (1967)
   PUBMED   6053733
REFERENCE   10 (bases 1 to 5360)
  AUTHORS   Green,E.L.
  TITLE     Shambling, a neurological mutant of the mouse
  JOURNAL   J Hered 58 (2), 65-68 (1967)
   PUBMED   6036114
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL590969.12, AF039833.1 and CN538743.1.
            
            On Oct 12, 2006 this sequence version replaced NM_016782.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF039833.1, SRR9219379.386.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-211               AL590969.12        213199-213409       c
            212-563             AF039833.1         222-573
            564-655             AL590969.12        211380-211471       c
            656-714             AL590969.12        211232-211290       c
            715-2205            AF039833.1         725-2215
            2206-2283           AL590969.12        206233-206310       c
            2284-2780           AF039833.1         2294-2790
            2781-2896           AL590969.12        204774-204889       c
            2897-3540           AF039833.1         2907-3550
            3541-4133           CN538743.1         68-660
            4134-5360           AL590969.12        198806-200032       c
FEATURES             Location/Qualifiers
     source          1..5360
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 64.33 cM"
     gene            1..5360
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /note="contactin associated protein-like 1"
                     /db_xref="GeneID:53321"
                     /db_xref="MGI:MGI:1858201"
     exon            1..211
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..4299
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /note="neurexin 4 (contactin associated protein); neurexin
                     IV; contactin-associated protein 1; paranodin; MHDNIV;
                     caspr1; neurexin-4"
                     /codon_start=1
                     /product="contactin-associated protein 1 precursor"
                     /protein_id="NP_058062.2"
                     /db_xref="CCDS:CCDS25455.1"
                     /db_xref="GeneID:53321"
                     /db_xref="MGI:MGI:1858201"
                     /translation="MMSLRLFSILLATVVSGAWGWGYYGCNEELVGPLYARSLGASSY
                     YGLFTTARFARLHGISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGAFNSWDWVTRYM
                     LLYGDRVDSWTPFYQKGHNATFFGNVNDSAVVRHDLHYHFTARYIRIVPLAWNPRGKI
                     GLRLGIYGCPYTSSILYFDGDDAISYRFQRGASQSLWDVFAFSFKTEEKDGLLLHTEG
                     SQGDYVTLELQGAHLLLHMSLGSSPIQPRPGHTTVSLGGVLNDLSWHYVRVDRYGRDA
                     NFTLDGYAHHFVLNGDFERLNLENEIFIGGLVGAARKNLAYRHNFRGCIENVIYNRIN
                     IAEMAVMRHSRITFEGNVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRT
                     WDLTGLLLFSHLGDGLGHVELMLSEGQVNVSIAQTGRKKLQFAAGYRLNDGFWHEVNF
                     VAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWGCHSNQTAFHGCM
                     ELLKVDGQLVNLTLVEFRKLGYFAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICY
                     CELTGYKGVTCHEPLYKESCEAYRLSGKYSGNYTIDPDGSGPLKPFVVYCDIRENRAW
                     TVVRHDRLWTTRVTGSSMDRPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSR
                     LLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDQSCVDPALHCNCDADQPQW
                     RTDKGLLTFVDHLPVTQVVVGDTNRSNSEAQFFLRPLRCYGDRNSWNTISFHTGAALR
                     FPPIRANHSLDVSFYFRTSAPSGVFLENMGGPFCRWRRPYVRVELNTSRDVVFAFDIG
                     NGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWLVYDQ
                     PLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTFPNCTGHCTHPRFPCFHG
                     GRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWMRYNLQSALRSAAREFSHMLS
                     RPVPGYEPGYVPGYDTPGYVPGYHGPGYRLPEYPRPGRPVPGYRGPVYNVTGEEVSFS
                     FSTNSAPAVLLYVSSFVRDYMAVLIKEDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHS
                     VNITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNT
                     PGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEAMRVQGELSESNCGAMPRLVSEVP
                     PELDPWYLPPDFPYYHDDGWIAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNE
                     PKATHDSHPGGKAPLPPSGPAQAPAPTPAPTQLPTPAPAPAPAPASGPGPRDQNLPQI
                     LEESRSE"
     exon            212..313
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            314..507
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            508..655
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            656..859
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            860..1044
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1188
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1450
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1600
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            1601..1772
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            1773..1879
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            1880..1999
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            2000..2203
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2360
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            2361..2488
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            2489..2674
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            2675..2896
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            2897..3136
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            3137..3490
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            3491..3618
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            3619..3712
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            3713..3958
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            3959..4006
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     exon            4007..5360
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5341..5346
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /note="hexamer: AATAAA"
     polyA_site      5359
                     /gene="Cntnap1"
                     /gene_synonym="Caspr; NCP1; Nrxn4; p190; shm"
                     /note="major polyA site"
ORIGIN      
        1 gggtaggaga gagggaaggg tggataagga cggaaaaaag ctttggtcag ccgtgaaccc
       61 aggagaaaag ctgggggcct gagccagaac gggagcccta gcggcgcaac aaggctgaca
      121 cccagcgttg gtcagctccg catgatgagt ctccggctct tcagcatcct gctcgccacg
      181 gtggtctctg gagcttgggg ctggggctac tacggttgca atgaggagct ggtggggcct
      241 ctgtatgcac ggtctctggg cgcttcttcc tactatggac tctttaccac agcccgcttt
      301 gcccggctac atggcatcag tggatggtcg ccccggattg gggacccgaa tccctggctg
      361 cagatcgact taatgaagaa gcatcggatc cgggctgtgg ccacacaggg agcttttaat
      421 tcttgggatt gggtcacacg ttacatgctg ctctacgggg accgtgtgga cagctggaca
      481 ccattctacc aaaaagggca caatgcgacc ttcttcggga atgtcaatga ctcggcagtg
      541 gtccgccatg accttcacta ccactttacg gctcgctaca tccgcatcgt gccactggcc
      601 tggaacccac gcggcaagat tggcctgagg ctgggcatct atggttgtcc ctacacatcc
      661 agcatcctgt attttgacgg cgacgatgcc atctcatacc gcttccagcg aggcgccagc
      721 caaagtcttt gggacgtgtt cgcttttagt ttcaagacag aggagaagga tgggctgttg
      781 ctgcacaccg agggctccca gggggattat gtgacgcttg aactgcaagg ggcgcacctg
      841 ctgctgcaca tgagcctggg cagcagtccc atccagccaa gacctggtca caccacggtg
      901 agccttggtg gcgttcttaa cgacctaagc tggcactatg tgcgggtgga tcgatatggc
      961 cgagatgcaa atttcaccct ggatggttac gcccatcact ttgtgctcaa cggcgacttt
     1021 gaaaggctga atcttgaaaa tgagatattc atcgggggtc tagtgggcgc agcccgtaag
     1081 aacctggcct accgccataa cttccgtggc tgcatagaaa acgtgatcta caaccggatc
     1141 aacattgcag aaatggcagt gatgcgccat tcgcggatca cctttgaggg taatgtggct
     1201 ttccgttgct tggatcccgt tccacacccc atcaacttcg gaggccctca caacttcgtc
     1261 caagtgcctg gctttccacg ccgaggacgc ttagccgtct cttttcgttt ccgcacctgg
     1321 gacctcacag ggctgctcct tttctcccac ttgggggacg ggctgggtca tgtggagctg
     1381 atgcttagcg aagggcaagt gaatgtatcc atcgcgcaga ctggccgcaa gaagcttcag
     1441 tttgctgctg ggtaccgcct gaatgatggc ttctggcacg aggtgaactt tgtggcacag
     1501 gaaaaccatg cagtcatcag tattgatgat gtggaagggg cagaggtcag ggtttcatac
     1561 ccactgctga tccgcacagg gacttcatac ttctttggtg gttgtcccaa accagccagt
     1621 cgatggggct gccactccaa ccagacagca ttccatggct gcatggagct gctcaaggtg
     1681 gacggtcaac tggtcaacct cactctggta gagtttcgga agctcggtta ttttgctgag
     1741 gtcctctttg acacatgtgg catcacagac agatgcagcc ctaacatgtg tgagcatgac
     1801 ggacgatgct accagtcttg ggatgacttc atctgctact gcgaacttac cggctacaag
     1861 ggagttacct gccacgaacc attgtacaag gagtcctgtg aggcctatcg gctcagtggg
     1921 aaatattctg gaaactacac cattgatcct gatggcagtg gacccctgaa gccgtttgtg
     1981 gtgtattgtg acatccgaga gaaccgagcg tggacagttg tgcggcatga caggctgtgg
     2041 accactcgag tgactggttc cagcatggac cggccctttc tgggggccat ccaatactgg
     2101 aatgcctcct gggaggaagt cagcgctctg gccaatgctt cccaacactg tgagcagtgg
     2161 atcgagtttt cctgctacaa ttcccggctg ctcaacactg caggaggcta cccctacagc
     2221 ttttggattg gccgcaatga ggaacagcat ttctactggg gaggctccca gcctgggatc
     2281 cagcgctgtg cctgtgggct ggaccagagc tgtgtggacc ctgcactgca ctgcaattgt
     2341 gatgccgacc agccacagtg gagaacagac aaggggctcc tgacctttgt agaccatctg
     2401 cctgtcactc aggtagtggt aggtgataca aaccgctcaa attctgaagc tcagttcttc
     2461 ctgaggcctc tgcgctgcta tggtgaccgc aattcctgga acaccatctc cttccacact
     2521 ggagctgcac tgcgtttccc tccgatccga gccaaccaca gcctcgatgt ctcattctac
     2581 ttcaggacct cggctccctc gggtgtcttc ctagagaaca tggggggtcc tttctgccgg
     2641 tggcgccgac cttacgtgag agtggagctc aacacatccc gggatgtggt ctttgccttt
     2701 gatattggca atggggatga gaacctgaca gtgcactcgg atgactttga gtttaacgat
     2761 gatgagtggc atttggtccg agctgaaatc aacgtgaagc aggcccggct gcgagtggat
     2821 caccggccct gggtgctaag gcccatgccc ctgcagacct acatctggct ggtgtatgac
     2881 caacccctct atgtgggatc tgcagagctt aagaggcgcc cttttgtggg ctgcttgagg
     2941 gccatgcgtt tgaatggagt gactctgaac ttggagggcc gtgccaatgc ctctgagggc
     3001 accttcccca actgcaccgg ccactgcacc cacccccggt tcccctgttt ccacggagga
     3061 cgctgtgtgg agcgatacag ctactacaca tgtgactgtg acctcacagc ttttgatggg
     3121 ccatactgca atcacgatat tggtggattc tttgagaccg gcacatggat gcgctataac
     3181 ctccagtcag cactgcgctc tgcagcccgg gagttctcac acatgctgag ccggccagtg
     3241 ccgggctatg agcctggcta tgttccaggc tacgacactc ctggttacgt gcctggatac
     3301 cacggccctg ggtaccgact gcccgagtac ccgaggcccg gccggccagt gcccgggtat
     3361 agggggcctg tctacaatgt tactggagag gaggtctcct tcagcttcag caccaactct
     3421 gctcctgccg tcctgctcta tgtcagctcc tttgtacgtg actacatggc tgtgctcatc
     3481 aaggaagacg ggaccctaca gcttcggtat cagttgggca ccagtcccta tgtgtaccag
     3541 ctaaccaccc ggccagtgac tgatggtcag ccccatagtg tcaacatcac ccgggtctac
     3601 cgaaacctct ttatccaggt ggactacttc ccgctgacag aacagaagtt ctctctcctg
     3661 gtggacagcc agctggactc acccaaggcc ttgtatctag ggcgtgtgat ggagacagga
     3721 gtcattgacc cagagattca gcggtacaac accccaggtt tctcaggctg cctgtctggt
     3781 gtccggttca acaatgtggc tcctctcaag acccatttcc gaacccctcg gcccatgact
     3841 gctgagctgg cggaggccat gcgggttcaa ggagaactgt cagaatctaa ctgtggagct
     3901 atgccacgcc ttgtctctga ggtgccacca gaacttgatc cctggtacct gcctccagat
     3961 ttcccatact accatgacga cggatggatt gccatactct taggtttttt ggtggccttc
     4021 ctgctgctgg ggcttgtggg aatgctggtg ctgttctatc tgcaaaatca tcgatacaag
     4081 ggctcctacc acaccaacga gcccaaggcc acccacgatt cccatcctgg cggcaaagct
     4141 cccctccctc cctcaggccc tgcccaggcc cctgccccta ctccagctcc cacacagctt
     4201 ccaaccccag ccccagcccc agccccagcc ccagcctctg gcccaggccc cagagaccag
     4261 aacctccccc agatcttgga ggagtccagg tctgaatgag tcacaagggc ttcagggacc
     4321 aaggccaact cctctaagtc ccctcagctc ctgccttccc cctcccttgc cagggacatt
     4381 tggctcttct aagcaggctc tgttcaccag gaggattccc ctcttgccaa gtttggtgcg
     4441 cagagctaca gatgggacca aagggagtgg ccgagcctca ctgcctaaac caatgccctg
     4501 ctcatccctc tacccccccc cccacccgcc cccagctcca gactgtttgc ctgccctaca
     4561 ggagaaagcc catgatgctg agacaggcct ttcctgccat ctctgtccca gctgctggca
     4621 aggattaaca acgaagggca ggggagatga actgcctccc ttcctgtgta cactatcagc
     4681 agggacagat gtgggggatc gagaggctgc taaaacacac cctggagcct cccctcctcc
     4741 tcctgccctg ctgaccggct gtcttccatc tgcttcctct cagctggggc tgagggaaga
     4801 acttcaccac ccccaccccc acctcactca accctttttg ttcttacaga gacaagaggc
     4861 ctgcctcagt ttagcacttt agtacctcca ctgcttcact tgcttcagcc aaagccataa
     4921 aaagcctgcc tgagtagaaa agataatgca gatgccctgc ctagccagcc ctctactctt
     4981 ccaccccttt tcaaaatatg caatagcctt ggtgcctgtg cgcaggcctg gccctctcca
     5041 atgcatgagg agccctcccc cctctgctca gaaatgctgc tgcgtttacc caggaggtca
     5101 tattctttat atatatttct tgttgcagag tctctctcca gagaactata tattactcta
     5161 attttttaat tatctgttta tatataaaag aactcagtgg gctgtcctgt gctatgccca
     5221 gtttgtagcg agctccttct gtgtttgatg tctcatgagt cctgccagcc actcacccac
     5281 gtgctgggcc tccactctag tgcagggcag agcctgctgt gccctcaact gagcaggttc
     5341 aataaagcag cgtggcagag
//
