LOCUS       NM_001411166            1172 bp    mRNA    linear   ROD 07-JAN-2025
DEFINITION  Mus musculus contactin 6 (Cntn6), transcript variant 14, mRNA.
ACCESSION   NM_001411166
VERSION     NM_001411166.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1172)
  AUTHORS   Ide,H., Miike,K., Ohmori,T., Maruyama,K., Izumi,Y., Tanigawa,S. and
            Nishinakamura,R.
  TITLE     Mouse embryonic kidney transplantation identifies maturation
            defects in the medulla
  JOURNAL   Sci Rep 14 (1), 30293 (2024)
   PUBMED   39639083
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1172)
  AUTHORS   Lo Giudice,Q., Wagener,R.J., Abe,P., Frangeul,L. and Jabaudon,D.
  TITLE     Developmental emergence of first- and higher-order thalamic neuron
            molecular identities
  JOURNAL   Development 151 (18) (2024)
   PUBMED   39348458
REFERENCE   3  (bases 1 to 1172)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 1172)
  AUTHORS   Zhang,H.Y., Wu,F.Y., Zhang,C.X., Wu,C.Y., Cui,R.J., Liu,X.Y.,
            Yang,L., Zhang,Y., Sun,F., Cheng,F., Yang,R.M., Song,H.D. and
            Zhao,S.X.
  TITLE     Contactin 6, A Novel Causative Gene for Congenital Hypothyroidism,
            Mediates Thyroid Hormone Biosynthesis Through Notch Signaling
  JOURNAL   Thyroid 34 (3), 324-335 (2024)
   PUBMED   38183624
  REMARK    GeneRIF: Contactin 6, A Novel Causative Gene for Congenital
            Hypothyroidism, Mediates Thyroid Hormone Biosynthesis Through Notch
            Signaling.
REFERENCE   5  (bases 1 to 1172)
  AUTHORS   Zhang,W., Huang,H., Gui,A., Mu,D., Zhao,T., Li,H., Watanabe,K.,
            Xiao,Z., Ye,H. and Xu,Y.
  TITLE     Contactin-6-deficient male mice exhibit the abnormal function of
            the accessory olfactory system and impaired reproductive behavior
  JOURNAL   Brain Behav 13 (4), e2893 (2023)
   PUBMED   36860170
  REMARK    GeneRIF: Contactin-6-deficient male mice exhibit the abnormal
            function of the accessory olfactory system and impaired
            reproductive behavior.
REFERENCE   6  (bases 1 to 1172)
  AUTHORS   Williams,S.E., Grumet,M., Colman,D.R., Henkemeyer,M., Mason,C.A.
            and Sakurai,T.
  TITLE     A role for Nr-CAM in the patterning of binocular visual pathways
  JOURNAL   Neuron 50 (4), 535-547 (2006)
   PUBMED   16701205
REFERENCE   7  (bases 1 to 1172)
  AUTHORS   Chen,B., Schaevitz,L.R. and McConnell,S.K.
  TITLE     Fezl regulates the differentiation and axon targeting of layer 5
            subcortical projection neurons in cerebral cortex
  JOURNAL   Proc Natl Acad Sci U S A 102 (47), 17184-17189 (2005)
   PUBMED   16284245
REFERENCE   8  (bases 1 to 1172)
  AUTHORS   Cui,X.Y., Hu,Q.D., Tekaya,M., Shimoda,Y., Ang,B.T., Nie,D.Y.,
            Sun,L., Hu,W.P., Karsak,M., Duka,T., Takeda,Y., Ou,L.Y., Dawe,G.S.,
            Yu,F.G., Ahmed,S., Jin,L.H., Schachner,M., Watanabe,K.,
            Arsenijevic,Y. and Xiao,Z.C.
  TITLE     NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell
            differentiation into oligodendrocytes
  JOURNAL   J Biol Chem 279 (24), 25858-25865 (2004)
   PUBMED   15082708
  REMARK    GeneRIF: NB-3/Notch1 pathway promotes neural progenitor cell
            differentiation into oligodendrocytes via Deltex1.
REFERENCE   9  (bases 1 to 1172)
  AUTHORS   Takeda,Y., Akasaka,K., Lee,S., Kobayashi,S., Kawano,H.,
            Murayama,S., Takahashi,N., Hashimoto,K., Kano,M., Asano,M.,
            Sudo,K., Iwakura,Y. and Watanabe,K.
  TITLE     Impaired motor coordination in mice lacking neural recognition
            molecule NB-3 of the contactin/F3 subgroup
  JOURNAL   J Neurobiol 56 (3), 252-265 (2003)
   PUBMED   12884264
  REMARK    GeneRIF: Mice deficient for NB-3 are slow to learn to stay on the
            rotating rod in the rotorod test during repeated trials and display
            dysfunction of equilibrium and vestibular senses in the wire hang
            and horizontal rod-walking tests.
REFERENCE   10 (bases 1 to 1172)
  AUTHORS   Lee,S., Takeda,Y., Kawano,H., Hosoya,H., Nomoto,M., Fujimoto,D.,
            Takahashi,N. and Watanabe,K.
  TITLE     Expression and regulation of a gene encoding neural recognition
            molecule NB-3 of the contactin/F3 subgroup in mouse brain
  JOURNAL   Gene 245 (2), 253-266 (2000)
   PUBMED   10717476
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC117728.10, AC116110.7 and AC153990.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.90796.1 [ECO:0000332]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-217               AC117728.10        151515-151731
            218-261             AC116110.7         19019-19062
            262-401             AC116110.7         61352-61491
            402-528             AC116110.7         135295-135421
            529-704             AC116110.7         142788-142963
            705-800             AC153990.2         111804-111899       c
            801-1172            AC153990.2         86617-86988         c
FEATURES             Location/Qualifiers
     source          1..1172
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 48.93 cM"
     gene            1..1172
                     /gene="Cntn6"
                     /gene_synonym="NB-3"
                     /note="contactin 6"
                     /db_xref="GeneID:53870"
                     /db_xref="MGI:MGI:1858223"
     exon            1..217
                     /gene="Cntn6"
                     /gene_synonym="NB-3"
                     /inference="alignment:Splign:2.1.0"
     exon            218..261
                     /gene="Cntn6"
                     /gene_synonym="NB-3"
                     /inference="alignment:Splign:2.1.0"
     exon            262..401
                     /gene="Cntn6"
                     /gene_synonym="NB-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             347..1087
                     /gene="Cntn6"
                     /gene_synonym="NB-3"
                     /note="isoform c precursor is encoded by transcript
                     variant 14; mNB-3; neural recognition molecule NB-3"
                     /codon_start=1
                     /product="contactin-6 isoform c precursor"
                     /protein_id="NP_001398095.1"
                     /db_xref="GeneID:53870"
                     /db_xref="MGI:MGI:1858223"
                     /translation="MRLLWKLVILLPLINSCAGEGRFSRPIFIQEPQDVIFPLDLSRS
                     EIILTCTANGYPSPHYRWKQNGTDIDFGMTYHYRLDGGSLAISSPRTDQDIGIYQCLA
                     TNPVGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGELSYAWTFN
                     DSPLYVQEDKRRFVSQDTGNLYFAKVEPSDVGNYTCFVTNKEAHRSVQGPPTPLVLRT
                     DGKNINYLQTPPGLLHCGQVFGAFFFFF"
     exon            402..528
                     /gene="Cntn6"
                     /gene_synonym="NB-3"
                     /inference="alignment:Splign:2.1.0"
     exon            529..704
                     /gene="Cntn6"
                     /gene_synonym="NB-3"
                     /inference="alignment:Splign:2.1.0"
     exon            705..800
                     /gene="Cntn6"
                     /gene_synonym="NB-3"
                     /inference="alignment:Splign:2.1.0"
     exon            801..1172
                     /gene="Cntn6"
                     /gene_synonym="NB-3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtatttcatg cttaagacca gagaggagcc acgcaatact cagtggataa aaggcttgca
       61 gtcccagctg ggaaaaagag tcccattatc tcccagctgc atagacattc catacggctt
      121 ggttctgcct ggatgcacag catgcctgac tgaggactcc agacagagtt ctgcagaaaa
      181 attgtaaaga tcccgagaca tttccctggt aagatccaat catgacttat tcagtgtatg
      241 gtctaattat tggtttagaa gatagattgc taacaaactg actagaagat acaatcttct
      301 ttcctgctga ttgcatggga gaaatttttg accttcgaac gtggagatga ggttgctatg
      361 gaaactggta attctgctgc cactcataaa ctcttgtgca ggtgagggtc gtttcagccg
      421 tcctattttt atccaggagc cacaagatgt catttttcct ttggatttat ctagatctga
      481 aattattctg acttgtactg caaatggata cccttctccc cattacaggt ggaaacagaa
      541 tggtacagat attgacttcg gcatgactta tcactatagg ttggatggag gcagtttggc
      601 catcagcagc cccagaacag atcaagatat tggcatatac cagtgtctgg ccaccaatcc
      661 tgtgggcacc attctgagta gaaaagccaa gctacagttt gcatatattg aagactttga
      721 aaccaaaacc agaagcacag tatctgtccg agaaggtcaa ggagtggtac tactctgtgg
      781 cccaccacca cattttggag aattatcata tgcctggacc ttcaatgata gccctttgta
      841 tgttcaagag gacaagcgaa gatttgtatc tcaagacaca gggaacttgt actttgccaa
      901 agtagaacca tctgatgtgg gcaattatac ttgctttgtc acaaacaaag aggcccatag
      961 aagtgtccaa ggtccaccta cgcctttagt gctgcgcact gatggtaaga acataaatta
     1021 tcttcagact ccccctggac tcttacattg tgggcaggtc ttcggagcct tttttttttt
     1081 tttttaactg taaccaaaat cactgtagtg tagatgaaat tcacatgcac agtgaagatg
     1141 agacattact aaaataaaaa aaaattaaaa aa
//
