LOCUS       NM_001170787            4270 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus contactin 5 (Cntn5), transcript variant 1, mRNA.
ACCESSION   NM_001170787
VERSION     NM_001170787.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4270)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4270)
  AUTHORS   Ehrman,J.M., Merchan-Sala,P., Ehrman,L.A., Chen,B., Lim,H.W.,
            Waclaw,R.R. and Campbell,K.
  TITLE     Formation of the Mouse Internal Capsule and Cerebral Peduncle: A
            Pioneering Role for Striatonigral Axons as Revealed in Isl1
            Conditional Mutants
  JOURNAL   J Neurosci 42 (16), 3344-3364 (2022)
   PUBMED   35273083
REFERENCE   3  (bases 1 to 4270)
  AUTHORS   Yan,W., Laboulaye,M.A., Tran,N.M., Whitney,I.E., Benhar,I. and
            Sanes,J.R.
  TITLE     Mouse Retinal Cell Atlas: Molecular Identification of over Sixty
            Amacrine Cell Types
  JOURNAL   J Neurosci 40 (27), 5177-5195 (2020)
   PUBMED   32457074
REFERENCE   4  (bases 1 to 4270)
  AUTHORS   Smirnov,A.V., Kontsevaya,G.V., Feofanova,N.A., Anisimova,M.V.,
            Serova,I.A., Gerlinskaya,L.A., Battulin,N.R., Moshkin,M.P. and
            Serov,O.L.
  TITLE     Unexpected phenotypic effects of a transgene integration causing a
            knockout of the endogenous Contactin-5 gene in mice
  JOURNAL   Transgenic Res 27 (1), 1-13 (2018)
   PUBMED   29264679
  REMARK    GeneRIF: These findings link Cntn5 deficiency to obesity and
            hypertension
REFERENCE   5  (bases 1 to 4270)
  AUTHORS   Peng,Y.R., Tran,N.M., Krishnaswamy,A., Kostadinov,D.,
            Martersteck,E.M. and Sanes,J.R.
  TITLE     Satb1 Regulates Contactin 5 to Pattern Dendrites of a Mammalian
            Retinal Ganglion Cell
  JOURNAL   Neuron 95 (4), 869-883 (2017)
   PUBMED   28781169
REFERENCE   6  (bases 1 to 4270)
  AUTHORS   Shimoda,Y., Koseki,F., Itoh,M., Toyoshima,M. and Watanabe,K.
  TITLE     A cis-complex of NB-2/contactin-5 with amyloid precursor-like
            protein 1 is localized on the presynaptic membrane
  JOURNAL   Neurosci Lett 510 (2), 148-153 (2012)
   PUBMED   22285261
  REMARK    GeneRIF: findings demonstrated that NB-2 interacts with APLP and
            that both NB-2 and APLP1 are localized at presynaptic sites,
            suggesting that NB-2 associates with APLP1 in a cis manner on the
            presynaptic membrane
REFERENCE   7  (bases 1 to 4270)
  AUTHORS   Yokoyama,K., Tezuka,T., Kotani,M., Nakazawa,T., Hoshina,N.,
            Shimoda,Y., Kakuta,S., Sudo,K., Watanabe,K., Iwakura,Y. and
            Yamamoto,T.
  TITLE     NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling
            in neurons
  JOURNAL   EMBO J 30 (23), 4739-4754 (2011)
   PUBMED   21946561
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 4270)
  AUTHORS   Toyoshima,M., Sakurai,K., Shimazaki,K., Takeda,Y., Shimoda,Y. and
            Watanabe,K.
  TITLE     Deficiency of neural recognition molecule NB-2 affects the
            development of glutamatergic auditory pathways from the ventral
            cochlear nucleus to the superior olivary complex in mouse
  JOURNAL   Dev Biol 336 (2), 192-200 (2009)
   PUBMED   19818338
  REMARK    GeneRIF: NB-2 deficiency causes a deficit in synapse formation and
            then induces apoptosis in MNTB and VCN neurons, affecting auditory
            brainstem function
REFERENCE   9  (bases 1 to 4270)
  AUTHORS   Williams,S.E., Grumet,M., Colman,D.R., Henkemeyer,M., Mason,C.A.
            and Sakurai,T.
  TITLE     A role for Nr-CAM in the patterning of binocular visual pathways
  JOURNAL   Neuron 50 (4), 535-547 (2006)
   PUBMED   16701205
REFERENCE   10 (bases 1 to 4270)
  AUTHORS   Li,H., Takeda,Y., Niki,H., Ogawa,J., Kobayashi,S., Kai,N.,
            Akasaka,K., Asano,M., Sudo,K., Iwakura,Y. and Watanabe,K.
  TITLE     Aberrant responses to acoustic stimuli in mice deficient for neural
            recognition molecule NB-2
  JOURNAL   Eur J Neurosci 17 (5), 929-936 (2003)
   PUBMED   12653969
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC107635.16, AC102350.14, AC113470.14, AC154645.3, AC118029.11,
            AC154651.2, AC153417.1 and CT033779.9.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.191232.1,
                                           SRR9219380.80413.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849376,
                                           SAMN00849381 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-291               AC107635.16        159787-160077
            292-432             AC102350.14        94382-94522         c
            433-556             AC113470.14        167859-167982
            557-775             AC154645.3         105459-105677       c
            776-899             AC154645.3         78861-78984         c
            900-1075            AC154645.3         77644-77819         c
            1076-1171           AC118029.11        147097-147192       c
            1172-1375           AC118029.11        105622-105825       c
            1376-1478           AC118029.11        69741-69843         c
            1479-1660           AC118029.11        41002-41183         c
            1661-1797           AC118029.11        33196-33332         c
            1798-1927           AC154651.2         171806-171935       c
            1928-2078           AC154651.2         169494-169644       c
            2079-2206           AC154651.2         32442-32569         c
            2207-2382           AC154651.2         30480-30655         c
            2383-2503           AC153417.1         40955-41075
            2504-2662           AC153417.1         74259-74417
            2663-2812           AC153417.1         79022-79171
            2813-2883           AC153417.1         116636-116706
            2884-3118           AC153417.1         117721-117955
            3119-3228           AC153417.1         129144-129253
            3229-3415           CT033779.9         5701-5887
            3416-3528           CT033779.9         6290-6402
            3529-3697           CT033779.9         12679-12847
            3698-4270           CT033779.9         18221-18793
FEATURES             Location/Qualifiers
     source          1..4270
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 2.46 cM"
     gene            1..4270
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /note="contactin 5"
                     /db_xref="GeneID:244682"
                     /db_xref="MGI:MGI:3042287"
     exon            1..291
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            292..432
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            433..556
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             502..3798
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; neural recognition molecule NB-2"
                     /codon_start=1
                     /product="contactin-5 isoform 1 precursor"
                     /protein_id="NP_001164258.1"
                     /db_xref="CCDS:CCDS52722.1"
                     /db_xref="GeneID:244682"
                     /db_xref="MGI:MGI:3042287"
                     /translation="MASCWRLILFLSVTRWLSDYSEALSGLSTSYAALLRIKKSSTSP
                     FGSKSRPRFSSPSLGTISVSPPSWRGAAQQYHSPGNLYHSSDAFRQDESVDYGPVFVQ
                     EPDDVIFPTDSDEKKVALNCEVRGNPSPSYRWLRNGTEIALESDYRYSLIDGTFIISN
                     PSELRDSGLYQCLATNSFGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSP
                     PPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNAVTN
                     ARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWM
                     KVNGYIPSKSRLRKSQAVLEIPNLQLDDAGIYECTAENSRGKNSFRGQLQIFTYPHWV
                     QKLNDTQLDSGSPLQWECKATGKPRPTYRWLKNGAPLLPQSRVDTVNGILAIQSVNQS
                     DAGMYQCLAENKYGAIYASAELKILASPPSFELNQVKKSIIVTKDRGVLIECEPQGSP
                     KPAISWRKGDKAVRANKRIAILPDGSLRILNASKADEGKYICQGVNIFGSAEIIASLS
                     VKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEKEGGHFEN
                     IRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGVVIVEEIT
                     ESTATLSWSPATDNHSPISSYNLQARSPFSLGWQTVKTVPEVITGDMESAMAVDLNPW
                     VEYEFRVVATNPIGTGDPSIPSRMIRTNEAVPKTAPSNVSGRSGRRHELVIAWEPVSE
                     EFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNK
                     GDGPFSQIVVICSAEGEPTAAPTDVTATSVSVSEIFVVWKHVKESLGRPQGFEISYWK
                     DTEPEDSVETVRTRGNESFVMLTGLEGNTLYHLTVRAYNGAGYGPPSREASTTTKRHP
                     PREPPGNLRWEQQGSQVSLGWEPVRPLANESEVMGYKVFYRQEGHSEGQVIETQKPQA
                     VVPLPEAGVYIIEVRAYSEGGDGTASSQIRVPSYSGGKITSAQSTLHSLSKWSSVTLL
                     LALMLPSSSW"
     exon            557..775
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            776..899
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            900..1075
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..1171
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1375
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1478
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1660
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..1797
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1798..1927
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1928..2078
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2079..2206
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2207..2382
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2383..2503
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2504..2662
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2663..2812
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2813..2883
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2884..3118
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3119..3228
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3229..3415
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3416..3528
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3529..3697
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3698..4270
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4008..4013
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /note="hexamer: AATAAA"
     polyA_site      4033
                     /gene="Cntn5"
                     /gene_synonym="6720426O10Rik; A830025P08Rik; Gm507; NB-2"
                     /note="major polyA site"
ORIGIN      
        1 ttgcacctgc ctgcatctct caactactcc gccccacgca actgatggca gccaagtgcc
       61 attaaagctg gcagtcagga ggatgcctca cctgggtccc ttctgctggg agaggcaggg
      121 caaaccagag gaaaattccc agtgaaggac tcagaactct gcgatttctc ttctgtcaca
      181 ggctgtggag cacctaagga actgctccac ctgaggtgtg tccagggcac gaggatggaa
      241 gatgaggatt gagaatcacc aaaatgaaca gaggcagctg gcgtctcatt ggtatttttg
      301 gaagactgct atttaatgct attcaagccc tgctaagcat cctttctgca tgacgaccac
      361 cacaaaagga ttactttaga gaaactgctg ccattttgaa gagtgtgatt tggagcctga
      421 ttcagaaaat aggatttttg tcaatgagga aacgtcagta gtaatcacca tccgggatcc
      481 aggagcggcc tgtgactaag catggcttcc tgttggagac tcattctgtt cctgtctgtc
      541 accaggtggc tttcagatta ctctgaagct ctctctggcc tttctacttc atatgctgct
      601 ttgctcagaa ttaagaagag ttcaacctca ccctttggtt ccaagtccag accacggttc
      661 agcagtcctt cattaggtac catcagtgtt tctccaccaa gctggcgagg ggcagctcag
      721 cagtaccact ccccaggcaa cctttatcac tcctcagatg ccttcagaca agatgaaagt
      781 gtggattatg ggccagtatt tgtgcaagaa cctgatgatg tcatttttcc aactgattct
      841 gatgaaaaga aggtagctct aaattgtgaa gttcgtggca acccatctcc tagttacaga
      901 tggcttcgga atggaactga aatagctctg gagagtgact atcgctacag tctgatagac
      961 ggcaccttca tcatcagcaa tccaagtgaa ctcagggatt ctggcctgta ccagtgctta
     1021 gccaccaact cttttggaag tattcttagt cgagaagcca ctcttcagtt tgcctatctg
     1081 ggaaatttta gtggccggac aagaagtgca gtctcagtgc gggaaggcca gggggttgtt
     1141 ctgatgtgct ctccaccacc acattctcca gagatcatct atagctgggt cttcaatgag
     1201 ttcccttcct ttgtggcaga ggacagccgg cggttcatat cccaagagac aggcaacctt
     1261 tatatttcta aagtgcaaac atccgatgtt ggcagctaca tttgtctggt gaaaaatgct
     1321 gtgacaaatg ctcgcgtgct cagtcctcca accccactca cgctgcgaaa tgatggtgtg
     1381 atgggagaat atgagccaaa aattgaggtc cattttcctt tcactgtcac agctgctaag
     1441 ggaacaactg tgaagatgga atgctttgca cttggcaacc cggttccaac aattacttgg
     1501 atgaaggtta acggttacat tcctagtaag tccagactgc ggaaatccca ggcagtgctg
     1561 gagattccaa acctgcagct ggatgatgcc ggaatatacg aatgcacagc tgaaaactcc
     1621 cgtggaaaaa actcctttcg tggacagcta caaatattca catacccaca ctgggtacag
     1681 aaactgaatg atacccagct ggacagtggg agtcctctgc agtgggaatg caaggctact
     1741 ggaaagccca gacccacata ccgctggctg aagaatggag cacccctctt gccgcagagc
     1801 agagtggaca cagtgaatgg aatattggcg atccagagtg tgaatcaatc agatgctggg
     1861 atgtatcagt gtttggctga gaataaatat ggagctattt atgcgagtgc tgagctgaag
     1921 attctagctt cgccgccctc cttcgaactg aatcaagtga agaaatccat aattgttacc
     1981 aaagaccggg gagtgctcat agagtgcgaa ccccagggat ctccaaagcc agccatctcc
     2041 tggaggaagg gagacaaggc agtgagggcg aataaaagaa tagctattct tccagacgga
     2101 agcctgagga tcctaaacgc ttctaaagca gatgagggga agtacatttg ccaaggggtg
     2161 aacatcttcg gttctgcaga gattatagct tccctgtctg tcaaagaacc cacaaggata
     2221 gagcttactc ctaaaagaac agagttaact gttggagaga gcattgtcct caactgtaaa
     2281 gctatccacg acgccagttt ggacgtcact ttctactgga cattaaaagg acaacctatt
     2341 gattttgaga aagaaggcgg acattttgaa aacatcaggg ctcaagcatc ctctgcagat
     2401 ttaatgatca ggaacatcct tctgatgcat gctgggagat atggctgcag ggtacagacc
     2461 acagcagaca gtgtgtcaga tgaggcagaa cttcttgtta ggggtccccc agggccacct
     2521 ggagtggtca tagtagagga gattacagaa agcacagcca ctctctcatg gagtccagca
     2581 actgacaacc atagccccat ctcttcttac aaccttcagg ctcgcagccc cttctccctg
     2641 ggctggcaaa cagtgaagac agtcccagaa gtcatcacag gagacatgga gtcagcaatg
     2701 gctgtggacc taaacccctg ggtagaatat gaattccgag tggtggccac caatccaatt
     2761 gggacaggag atccaagcat tccatctcga atgatccgca caaatgaggc agttccaaag
     2821 acggcaccca gcaacgtgag tggaagaagt ggaagaaggc atgagttggt cattgcctgg
     2881 gagccagtat cagaagagtt tcagaatggg gaaggcttcg gctacatagt ggcattcaga
     2941 cctaatggaa cacgtggctg gaaggagaaa atggttacgt cttcggaggc gtccaagttc
     3001 atttaccgag atgaaagtgt ccctcctctc acaccctttg aggtcaaagt tggtgtttat
     3061 aataataaag gtgatgggcc tttcagccag atcgtagtca tctgttcagc tgagggagaa
     3121 cccactgctg ctcccactga cgtcacagca accagtgtgt cagtgtcaga gatttttgtt
     3181 gtatggaaac atgttaagga gagtcttgga agaccacagg ggtttgagat tagttactgg
     3241 aaagataccg agccagaaga ctccgtagaa acagtccgaa ccagagggaa tgagtcattc
     3301 gtcatgttga cgggattgga aggcaacaca ctctatcacc tcacagtcag ggcttacaat
     3361 ggagccggct atgggccacc cagcagggaa gcaagcacca ccacaaagag gcacccccct
     3421 agggagccac ctggcaacct ccggtgggag cagcagggct cccaagtttc cctaggctgg
     3481 gagccagtca gacccctagc caatgagtct gaagtcatgg gttacaaggt tttttatagg
     3541 caagagggtc acagcgaagg tcaagttatt gagacacaga aacctcaagc tgtagtgcct
     3601 ctacctgagg ctggagtcta cattattgaa gttcgagcgt acagtgaggg aggagatgga
     3661 acagctagct cccaaatcag ggttccttca tattcaggtg ggaaaatcac aagcgctcag
     3721 tcaaccctgc actctctctc caagtggtcc tcagtaacac tgctcttggc tttgatgctt
     3781 ccttccagtt cctggtgaaa gctgctcatg cagtgtggtt ttctttgctt tagctcgaga
     3841 aagcggcagc aaacagaata cagaatgaat ggagactggg ttcctgagaa aagctttgaa
     3901 cacacgggac tacagatggt gccctctcag gagttttggg ggagaatagg agttacccat
     3961 caggtttctc ttgggatttt gtaaatggag aggacagttc ttagtccaat aaaaatatgc
     4021 agattgtatg taatgaaatt ttgtaagcac aggtaatttc tgtcagatgt attcttaaac
     4081 tttttaatat gttgggattt gatttttcta tttaatggct ctgagtgtca tctatccatt
     4141 gctgaggtgg tctctatagc ctgctcaaag tcaaatacaa acccaagaga agaaatgtct
     4201 tctcaagact ttgtgtctaa tgtttttcaa acttcccatt agatcactgc ttcaatacaa
     4261 aaccagcagg
//
