LOCUS       NM_001411732            5809 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus contactin 4 (Cntn4), transcript variant 21, mRNA.
ACCESSION   NM_001411732 XM_036166173
VERSION     NM_001411732.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5809)
  AUTHORS   Bamford,R.A., Zuko,A., Eve,M., Sprengers,J.J., Post,H.,
            Taggenbrock,R.L.R.E., Fabetaler,D., Mehr,A., Jones,O.J.R.,
            Kudzinskas,A., Gandawijaya,J., Muller,U.C., Kas,M.J.H.,
            Burbach,J.P.H. and Oguro-Ando,A.
  TITLE     CNTN4 modulates neural elongation through interplay with APP
  JOURNAL   Open Biol 14 (5), 240018 (2024)
   PUBMED   38745463
  REMARK    GeneRIF: CNTN4 modulates neural elongation through interplay with
            APP.
REFERENCE   2  (bases 1 to 5809)
  AUTHORS   Chen,P., Liu,Z., Zhang,Q., Lin,D., Song,L., Liu,J., Jiao,H.F.,
            Lai,X., Zou,S., Wang,S., Zhou,T., Li,B.M., Zhu,L., Pan,B.X. and
            Fei,E.
  TITLE     DSCAM Deficiency Leads to Premature Spine Maturation and
            Autism-like Behaviors
  JOURNAL   J Neurosci 42 (4), 532-551 (2022)
   PUBMED   34848499
REFERENCE   3  (bases 1 to 5809)
  AUTHORS   Zhao,R., Zhu,T., Liu,Q., Tian,Q., Wang,M., Chen,J., Tong,D., Yu,B.,
            Guo,H., Xia,K., Qiu,Z. and Hu,Z.
  TITLE     The autism risk gene CNTN4 modulates dendritic spine formation
  JOURNAL   Hum Mol Genet 31 (2), 207-218 (2021)
   PUBMED   34415325
REFERENCE   4  (bases 1 to 5809)
  AUTHORS   Oguro-Ando,A., Bamford,R.A., Sital,W., Sprengers,J.J., Zuko,A.,
            Matser,J.M., Oppelaar,H., Sarabdjitsingh,A., Joels,M.,
            Burbach,J.P.H. and Kas,M.J.
  TITLE     Cntn4, a risk gene for neuropsychiatric disorders, modulates
            hippocampal synaptic plasticity and behavior
  JOURNAL   Transl Psychiatry 11 (1), 106 (2021)
   PUBMED   33542194
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5809)
  AUTHORS   Filova,I., Dvorakova,M., Bohuslavova,R., Pavlinek,A., Elliott,K.L.,
            Vochyanova,S., Fritzsch,B. and Pavlinkova,G.
  TITLE     Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of
            Auditory Nerve Fibers
  JOURNAL   Mol Neurobiol 57 (12), 5307-5323 (2020)
   PUBMED   32880858
REFERENCE   6  (bases 1 to 5809)
  AUTHORS   Williams,S.E., Grumet,M., Colman,D.R., Henkemeyer,M., Mason,C.A.
            and Sakurai,T.
  TITLE     A role for Nr-CAM in the patterning of binocular visual pathways
  JOURNAL   Neuron 50 (4), 535-547 (2006)
   PUBMED   16701205
REFERENCE   7  (bases 1 to 5809)
  AUTHORS   Hansford,L.M., Smith,S.A., Haber,M., Norris,M.D., Cheung,B. and
            Marshall,G.M.
  TITLE     Cloning and characterization of the human neural cell adhesion
            molecule, CNTN4 (alias BIG-2)
  JOURNAL   Cytogenet Genome Res 101 (1), 17-23 (2003)
   PUBMED   14571131
REFERENCE   8  (bases 1 to 5809)
  AUTHORS   Saito,H., Mimmack,M., Kishimoto,J., Keverne,E.B. and Emson,P.C.
  TITLE     Expression of olfactory receptors, G-proteins and AxCAMs during the
            development and maturation of olfactory sensory neurons in the
            mouse
  JOURNAL   Brain Res Dev Brain Res 110 (1), 69-81 (1998)
   PUBMED   9733924
REFERENCE   9  (bases 1 to 5809)
  AUTHORS   Cangiano,G., Ambrosini,M., Patruno,A., Tino,A., Buttiglione,M. and
            Gennarini,G.
  TITLE     Functional organization of the promoter region of the mouse F3
            axonal glycoprotein gene
  JOURNAL   Brain Res Mol Brain Res 48 (2), 279-290 (1997)
   PUBMED   9332725
REFERENCE   10 (bases 1 to 5809)
  AUTHORS   Mimmack,M.L., Saito,H., Evans,G., Bresler,M., Keverne,E.B. and
            Emson,P.C.
  TITLE     A novel splice variant of the cell adhesion molecule BIG-2 is
            expressed in the olfactory and vomeronasal neuroepithelia
  JOURNAL   Brain Res Mol Brain Res 47 (1-2), 345-350 (1997)
   PUBMED   9221934
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153596.5, AC162466.6, AC153898.4, AC156281.4, AC153991.3,
            AC159546.4, AC153988.5 and AC164169.8.
            
            On Sep 1, 2022 this sequence version replaced XM_036166173.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.143604.1,
                                           SRR9219382.84297.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-224               AC153596.5         116584-116807       c
            225-368             AC162466.6         125456-125599
            369-424             AC153898.4         77754-77809
            425-572             AC156281.4         8572-8719           c
            573-699             AC153991.3         155698-155824
            700-875             AC153991.3         164564-164739
            876-971             AC159546.4         62629-62724
            972-1169            AC159546.4         114354-114551
            1170-1272           AC159546.4         130899-131001
            1273-1457           AC159546.4         134129-134313
            1458-1594           AC159546.4         148265-148401
            1595-1724           AC159546.4         150122-150251
            1725-1875           AC159546.4         175127-175277
            1876-2003           AC153988.5         29109-29236         c
            2004-2179           AC164169.8         109702-109877
            2180-2297           AC164169.8         116775-116892
            2298-2456           AC164169.8         121575-121733
            2457-2606           AC164169.8         126986-127135
            2607-2719           AC164169.8         132540-132652
            2720-2906           AC164169.8         133450-133636
            2907-3019           AC164169.8         134071-134183
            3020-3188           AC164169.8         148468-148636
            3189-5809           AC164169.8         151720-154340
FEATURES             Location/Qualifiers
     source          1..5809
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 48.93 cM"
     gene            1..5809
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /note="contactin 4"
                     /db_xref="GeneID:269784"
                     /db_xref="MGI:MGI:1095737"
     exon            1..224
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            225..368
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            369..424
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            425..572
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             518..3289
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /note="isoform 6 precursor is encoded by transcript
                     variant 21; brain-derived immunoglobulin superfamily
                     molecule; brain-derived immunoglobulin superfamily protein
                     2; axonal-associated cell adhesion molecule"
                     /codon_start=1
                     /product="contactin-4 isoform 6 precursor"
                     /protein_id="NP_001398661.1"
                     /db_xref="GeneID:269784"
                     /db_xref="MGI:MGI:1095737"
                     /translation="MRLPWELLVLQSFMLCLADDYTLHGPVFVQEPSHVMFPLDSEEK
                     KVKLSCEVKGNPKPHIRWKINGTDVDIGMDFRYSVVDGSLLINNPNKTQDAGTYQCIA
                     TNSFGTIVSREAKLQFAYLENFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFN
                     EYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDG
                     VMGEYEPKIEVQFPETVPAEKGTTVKLECFALGNPVPTILWRRADGKPIARKARRHKS
                     NGILEIPNFQQEDAGSYECVAENSRGKNVAKGQLTFYAQPNWVQIINDIHVAMEESVF
                     WECKANGRPKPTYRWLKNGDPLLTRDRIQIEQGTLNITIVNLSDAGMYQCVAENKHGV
                     IFSSAELSVIAESPDFSRTLLKRVTLVKVGGEVVIECKPKASPRPVYTWRKGREILRE
                     NERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNVIVKDPTKVMVPPSSMD
                     VTVGESIVLPCQVTHDHSLDIVFTWTFNGHLIDFDKDGDHFERVGGDSAGDLMIRNIQ
                     LKHAGKYVCMVQTSVDKLSVAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHS
                     PITMYVIQARTPFSVGWQAVNTVPDLVDGKTFTATVVGLNPWVEYEFRTVAANVIGIG
                     EPSRPSEKRRTEEAQPTKPPASIFARSLSATDIEVFWASPIGKNRGRIQGYEVKYWRH
                     DDKEENAKKIRTVGNQTSTKITNLKGSALYHLSVKAYNSAGTGPSSATVNVTTRKPPP
                     SQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVE
                     LSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNSYARGSGASTSNACTLSAISTIM
                     ISLTARSSL"
     exon            573..699
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            700..875
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            876..971
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1169
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1272
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1457
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1594
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..1724
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1725..1875
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1876..2003
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2179
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..2297
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2298..2456
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2457..2606
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2607..2719
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2720..2906
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2907..3019
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3020..3188
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3189..5809
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4953..4958
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /note="hexamer: AATAAA"
     polyA_site      4978
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /note="major polyA site"
     regulatory      5786..5791
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /note="hexamer: AATAAA"
     polyA_site      5809
                     /gene="Cntn4"
                     /gene_synonym="9630050B05; Axcam; BIG-2"
                     /note="major polyA site"
ORIGIN      
        1 gagtcttccg ctagtggctg caaaggaacc gctgcagcct gaactcaggt gcgccgggtt
       61 ttgagagctg ccaccagcac agggagggag aggaacgcgc ggcagccaca gagcacaagg
      121 ttcataacca ggattggtcg caagtaggga gcttttgcca ctccgccggg accttcggac
      181 gttggcggtg gagcaagccc agttctccta ggcgctgtgc ttggattcat attgcattgt
      241 tgacaattct cacaggtgaa attcggccag agctcacttg gaaatttctg cagattggtg
      301 taagagaatc agattcttca tgctcagcta aaggaaacaa tcctcgtggt tcttattgaa
      361 aagaagaggg attattgaca catactaatt caccagcatg tggctctcag aactgcccta
      421 agagattaaa ggttgcacaa agcttaaaag gaacagaagc agcagttcta ttcacttgtt
      481 attggacttg aaactccttt gacctgggaa actgaagatg aggttgccat gggaactgct
      541 agtgctgcaa tcattcatgt tgtgccttgc agatgactac acactgcatg gcccagtttt
      601 tgttcaagaa ccaagtcatg tcatgtttcc tttggattct gaggagaaaa aagtgaaact
      661 cagttgtgaa gttaaaggga atccaaaacc tcacatcagg tggaagataa atggaacaga
      721 tgttgacatt ggtatggatt tccgctacag tgttgttgac ggcagcttgt tgatcaataa
      781 ccccaataaa acccaagatg ctggaacgta ccagtgcata gcaacaaact catttggaac
      841 aattgtaagc agagaagcaa agcttcagtt tgcttatctt gaaaacttta agacaagaac
      901 aagaagcact gtgtcagtcc gtcgaggtca gggaatggtc cttctgtgcg gcccgccacc
      961 ccattctgga gagctgagct atgcctggat cttcaatgaa tacccttcct atcaggataa
     1021 ccgccgcttc gtttctcaag agactgggaa tctgtatatt gccaaagtgg aaaaatctga
     1081 tgttggtaat tacacctgtg tagttaccaa cactgtgacc aaccacaagg tcctgggacc
     1141 gcccacacca ctaatcctga gaaatgatgg ggtgatgggt gaatatgagc ccaaaataga
     1201 agtacagttt ccagaaaccg tcccggctga gaaaggaaca acagtcaaac tggaatgctt
     1261 tgccttagga aatccagtcc caactattct atggcgaaga gctgatggca agccaatagc
     1321 aaggaaagcc agaagacata agtcgaatgg aattctggaa attcccaatt ttcagcagga
     1381 agatgccggt tcatatgaat gtgtggctga aaactccaga ggcaaaaacg tagccaaggg
     1441 acagttgact ttttatgctc aacctaactg ggttcaaata ataaatgata tccacgtggc
     1501 catggaagag agtgtcttct gggaatgtaa agcaaatggg aggcctaaac ctacctacag
     1561 atggctaaaa aatggtgacc cactgttaac acgggataga atacaaatcg agcaaggaac
     1621 actcaacata acaatagtga atctctcaga tgctggcatg taccagtgtg tggcagaaaa
     1681 taaacatgga gttatctttt ccagcgctga gcttagtgta atagctgaaa gtccagattt
     1741 ttcccgaaca ctcttaaaaa gagtaacact tgtcaaagtg ggaggtgaag ttgtcattga
     1801 gtgcaagcca aaagcatccc caagacctgt ctacacctgg agaaagggaa gagaaatatt
     1861 aagagaaaat gaaagaatta ccatttctga agatgggaac ctcagaatca tcaatgtgac
     1921 taaatctgat gctggaagtt acacctgcat agccacgaac cattttggaa ctgccagcag
     1981 tactgggaat gtgattgtga aagacccaac aaaggtgatg gttcctcctt ccagcatgga
     2041 tgtcactgta ggagaaagca ttgttcttcc atgccaggta acacatgatc actccctgga
     2101 cattgtgttt acgtggacat ttaatggaca cttgatagac tttgacaagg atggagacca
     2161 ctttgaaaga gttggagggg attcagctgg tgatttgatg atccgaaaca tccaactgaa
     2221 gcatgctggg aagtatgtct gcatggtcca aacaagtgta gacaaactct ctgttgctgc
     2281 ggacctgatt gtaagaggtc ctccaggtcc tcctgaggct gtgaccatag atgaaatcac
     2341 agacaccact gctcagcttt cttggagacc aggacctgac aaccacagcc ccatcaccat
     2401 gtatgttatc caagctagga ctccattctc cgtgggctgg caagcagtca atacagttcc
     2461 agatctcgtc gacgggaaga cattcacagc aactgtggtg ggtttgaatc cttgggttga
     2521 atatgaattc cgcactgttg cagctaatgt gattggcatt ggggaaccca gccggccctc
     2581 agagaaacgg aggacagaag aggctcaacc caccaagcca ccagccagta tctttgccag
     2641 gagtctttct gccacggata tcgaagtttt ctgggcctcc cctattggaa agaacagagg
     2701 acggattcaa ggttatgagg taaaatattg gagacatgat gacaaggaag aaaatgctaa
     2761 aaagatacga acagttggaa atcagacatc cacaaaaatc accaacttga aaggaagtgc
     2821 tctgtatcac ttatctgtca aggcgtataa ctcagctggg acaggaccct ccagtgcaac
     2881 agtcaatgtc acgaccagaa agccaccacc aagccaaccc cctggaaaca tcatatggaa
     2941 ttcatcggac tccaaaatta tcctgaactg ggatcaagtg aaggccctgg ataatgagtc
     3001 agaagtaaaa ggatacaaag tcttgtacag atggaacagg caaagcagca catctgtcat
     3061 tgaaaccaac aagacatcag tggagctttc attacctttc gatgaagatt acatcataga
     3121 gatcaagcca ttcagtgatg gaggagatgg cagcagcagt gagcaaatcc gaatcccaaa
     3181 gatatcaaat tcctatgcaa gaggatcggg ggcttctacc tccaatgcgt gtacgctgtc
     3241 agccatcagt acaataatga tttctctcac agccaggtct agtttatgac aaaagttatc
     3301 tgaaggactt gctatttata atataagcaa catttagcta gttgttttga agacacccag
     3361 tactaagtaa tattgttgtt caagtacatc ttattactgg aaaaaaatgt tttttgcttc
     3421 gttaggaatg gcattataca gtacttcctc aaagcaaatc tagctttgtc tgaagtttct
     3481 ttggaaactc tgcaatgcac tgaagacatc tgtaatatga tgttaccaaa gcagtttaca
     3541 tatgtcctta tatgcatatt ttttattata tatttagtgt tttatagaat tttttaaagt
     3601 taacatataa tatagatatt gtttttttct ttcttcctct gctataaaat gctctgggca
     3661 acacaaacca cacaattatg atttgagccg atttccttta agggcagagt ttgaaactca
     3721 tcacagcaaa tgaattacaa atgacttgta cagttttaca aggatccagt gtcaaaacag
     3781 ctggagactg ggtctgtaac tcaaggctgc tgtatataaa ttatcccttg aatggttaat
     3841 gcattgaatc gagtcccctt gacatatgtg atatgttttc ccaccctgtt gtgaattttc
     3901 ttgttgaaca caatttgaga tggtttcagg aactacacat cccaaaagct aaacttccca
     3961 gcccaagagg taccttgtgc aattctccca tccctgaact tagcatcatc tggtaagact
     4021 ttatttgagc atcgtctttg tagtagcatt atcttaggca ttgaatttga agttacatat
     4081 cctgtagtaa catagatgaa aagttactat agtcaaacaa gtctttcatg gcataaaagg
     4141 taattttact ctttagacat atctgttttg aatgtaaatt ttttaataat tctgtcaatg
     4201 catttataat ttcaaaattt cttatagata acatgtgtaa ctgtaatgat agagcccttc
     4261 ttttgaatga caataacata tgtaatttga aatttttttc ctattttagc aaatagctgc
     4321 tgcaaagaat tttacatata actctataac tatccgtagt acagatgtat tgtatcttga
     4381 tgtctctccc gttttgcagt agctagtctg gttgctttat aagctttgca ttctacatct
     4441 taaaatgata caatgaaaga tggcaatatt gacaaacctt attcttacga aaagaactat
     4501 ttattacgat gggggatgtt ttgtaagctg acaagggtgg aacataaaag gcaatgagat
     4561 tttctataaa gcgttgcaca tgaaaacaca cagtcacctt tttcttcttt cttggagagc
     4621 tcacgattgc ctgtaatttg tcatttttgc ttacacataa catagccttt caacttgcta
     4681 attatattca tccaataaag gcatcattga ttccatttgt gtaaaaatta ggatggtaac
     4741 agggaaaata ttgtcagtat ttcagctgtg ttcctttctt actttgatat ggcatacttc
     4801 tatgttaaaa tatgatttaa aatcacatgc aaaaaaatca acaaagtaat aaaatgaatg
     4861 aaaaaaactg ataccccagg tagttcccaa ccccagtgta aatgatatct accagtgatc
     4921 tagcatatgt aatctttttt aaaggtattg ttaataaata ttctgtcatt tgtaaaaata
     4981 tctgccttct gggagcatta ttctttcctg cttgtcaggg aaatttttag cttacccttg
     5041 tgctagttac aacttgggat cgtaggggga caaaaaagtc tcgagctctg gccccaaaac
     5101 taggtgaccc aattccaaat gtgactttga aattgacaac cctgaagaca ccatttcaaa
     5161 tcccctttgg aagcatagag gagcaaactc aagtaacata tgtcttgaag ctgaggctag
     5221 aattttgttt ttcttggcta gccaagattt tgtatatttg atctaagtat acctgttgtt
     5281 ttccctaccc attgccaaaa tcataaaatc tctataatct taagcacgta aggcccttct
     5341 tagtctacaa tctcttactc ctatatacag ccacactgag ccctacttgt tccctgaaca
     5401 ctgcttgctt ttgatctcac ctctgtgcct ttcgggactc atggctgttc cttcttgaaa
     5461 tgttttcctc tctctcgcac ccaaatatca atcatcctag ggttccacca acactccagc
     5521 tcatctatga ggtcttccca tatgtgtgac cttgtgatgt cctccctctg aatttgctgc
     5581 aaccttccat ttagtatttc atagggtact acttttggaa atatcttgta ctgttatctt
     5641 gcatttgaac ctagctcttg tattgttcct gacttttctt tgaatgtatg ccttgtcttc
     5701 ccaactagat tgtaagctcc ttgagggcag ggatattggt cttctcttcc atgtactctg
     5761 catagtgcct agcacagtgc cttgcaataa atattcattg atgaattga
//
