LOCUS       NM_008779               5445 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus contactin 3 (Cntn3), mRNA.
ACCESSION   NM_008779 XM_006505725
VERSION     NM_008779.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5445)
  AUTHORS   Tenney,A.P., Livet,J., Belton,T., Prochazkova,M., Pearson,E.M.,
            Whitman,M.C., Kulkarni,A.B., Engle,E.C. and Henderson,C.E.
  TITLE     Etv1 Controls the Establishment of Non-overlapping Motor
            Innervation of Neighboring Facial Muscles during Development
  JOURNAL   Cell Rep 29 (2), 437-452 (2019)
   PUBMED   31597102
REFERENCE   2  (bases 1 to 5445)
  AUTHORS   Peng,X., Williams,J., Smallwood,P.M. and Nathans,J.
  TITLE     Defining the binding interface of Amyloid Precursor Protein (APP)
            and Contactin3 (CNTN3) by site-directed mutagenesis
  JOURNAL   PLoS One 14 (7), e0219384 (2019)
   PUBMED   31318883
  REMARK    GeneRIF: These experiments define the regions of direct contact
            that mediate the binding interaction between APP and CNTN3.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5445)
  AUTHORS   Nikolaienko,R.M., Hammel,M., Dubreuil,V., Zalmai,R., Hall,D.R.,
            Mehzabeen,N., Karuppan,S.J., Harroch,S., Stella,S.L. and Bouyain,S.
  TITLE     Structural Basis for Interactions Between Contactin Family Members
            and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues
  JOURNAL   J Biol Chem 291 (41), 21335-21349 (2016)
   PUBMED   27539848
  REMARK    GeneRIF: Protein-tyrosine phosphatase receptor type G
            (RPTPgamma/PTPRG) interacts in vitro with contactin-3-6 (CNTN3-6),
            a group of glycophosphatidylinositol-anchored cell adhesion
            molecules involved in the wiring of the nervous system
REFERENCE   4  (bases 1 to 5445)
  AUTHORS   Gu,Z., Imai,F., Kim,I.J., Fujita,H., Katayama,Ki., Mori,K.,
            Yoshihara,Y. and Yoshida,Y.
  TITLE     Expression of the immunoglobulin superfamily cell adhesion
            molecules in the developing spinal cord and dorsal root ganglion
  JOURNAL   PLoS One 10 (3), e0121550 (2015)
   PUBMED   25826454
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5445)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   6  (bases 1 to 5445)
  AUTHORS   Street,V.A., McKee-Johnson,J.W., Fonseca,R.C., Tempel,B.L. and
            Noben-Trauth,K.
  TITLE     Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in
            deafwaddler mice
  JOURNAL   Nat Genet 19 (4), 390-394 (1998)
   PUBMED   9697703
REFERENCE   7  (bases 1 to 5445)
  AUTHORS   McKee-Johnson,J.W., Street,V.A., Erford,S.K., Robinson,L.C. and
            Tempel,B.L.
  TITLE     Physical and genetic maps of the deafwaddler region on distal mouse
            Chr 6
  JOURNAL   Genomics 49 (3), 371-377 (1998)
   PUBMED   9615221
REFERENCE   8  (bases 1 to 5445)
  AUTHORS   Mock,B.A., Connelly,M.A., McBride,O.W., Kozak,C.A. and Marcu,K.B.
  TITLE     Plasmacytoma-associated neuronal glycoprotein, Pang, maps to mouse
            chromosome 6 and human chromosome 3
  JOURNAL   Genomics 34 (2), 226-228 (1996)
   PUBMED   8661054
REFERENCE   9  (bases 1 to 5445)
  AUTHORS   Yoshihara,Y., Kawasaki,M., Tani,A., Tamada,A., Nagata,S.,
            Kagamiyama,H. and Mori,K.
  TITLE     BIG-1: a new TAG-1/F3-related member of the immunoglobulin
            superfamily with neurite outgrowth-promoting activity
  JOURNAL   Neuron 13 (2), 415-426 (1994)
   PUBMED   8060619
REFERENCE   10 (bases 1 to 5445)
  AUTHORS   Connelly,M.A., Grady,R.C., Mushinski,J.F. and Marcu,K.B.
  TITLE     PANG, a gene encoding a neuronal glycoprotein, is ectopically
            activated by intracisternal A-type particle long terminal repeats
            in murine plasmacytomas
  JOURNAL   Proc Natl Acad Sci U S A 91 (4), 1337-1341 (1994)
   PUBMED   8108413
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153597.13, AC153600.8, AC155328.5 and AC114423.16.
            
            On or before Mar 24, 2022 this sequence version replaced
            XM_006505725.5, NM_008779.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.342739.1,
                                           SRR9219380.59148.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849377 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-264               AC153597.13        50239-50502
            265-399             AC153597.13        149990-150124
            400-526             AC153597.13        176724-176850
            527-702             AC153600.8         185926-186101       c
            703-798             AC155328.5         185909-186004       c
            799-1002            AC155328.5         126889-127092       c
            1003-1105           AC155328.5         125830-125932       c
            1106-1290           AC155328.5         122251-122435       c
            1291-1427           AC155328.5         117715-117851       c
            1428-1557           AC155328.5         115985-116114       c
            1558-1708           AC155328.5         113930-114080       c
            1709-1836           AC155328.5         93656-93783         c
            1837-2012           AC155328.5         90601-90776         c
            2013-2130           AC155328.5         57850-57967         c
            2131-2289           AC155328.5         56925-57083         c
            2290-2439           AC155328.5         56670-56819         c
            2440-2510           AC155328.5         55138-55208         c
            2511-2745           AC155328.5         52443-52677         c
            2746-2861           AC155328.5         47847-47962         c
            2862-3048           AC155328.5         35651-35837         c
            3049-3161           AC114423.16        195458-195570       c
            3162-3330           AC114423.16        193773-193941       c
            3331-5445           AC114423.16        188184-190298       c
FEATURES             Location/Qualifiers
     source          1..5445
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 47.52 cM"
     gene            1..5445
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /note="contactin 3"
                     /db_xref="GeneID:18488"
                     /db_xref="MGI:MGI:99534"
     exon            1..264
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            265..399
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     CDS             345..3431
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /note="BIG-1; brain-derived immunoglobulin superfamily
                     protein 1; plasmacytoma-associated neuronal glycoprotein"
                     /codon_start=1
                     /product="contactin-3 precursor"
                     /protein_id="NP_032805.2"
                     /db_xref="CCDS:CCDS39581.1"
                     /db_xref="GeneID:18488"
                     /db_xref="MGI:MGI:99534"
                     /translation="MMLSWKQLILLSFIGCLAGELLLQGPVFIKEPSNSIFPVDSEDK
                     KITLNCEARGNPSPHYRWQLNGSDIDTSLDHRYKLNGGNLIVINPNRNWDTGSYQCFA
                     TNSLGTIVSREAKLQFAYLENFKTRMRSTVSVREGQGVVLLCGPPPHSGELSYAWVFN
                     EYPSFVEEDSRRFVSQETGHLYIAKVEPSDVGNYTCVVTSTVTNTRVLGSPTPLVLRS
                     DGVMGEYEPKIEVQFPETLPAAKGSTVRLECFALGNPVPQINWRRSDGMPFPNKIKLR
                     KFNGMLEIQNFQQEDTGSYECIAENSRGKNVARGRLTYYAKPYWLQLLRDVEIAVEDS
                     LYWECRASGKPKPSYRWLKNGDALVLEERIQIENGALTITNLNVTDSGMFQCIAENKH
                     GLIYSSAELKVVASAPDFSRNPMKKMVQVQVGSLVILDCKPRASPRALSFWKKGDMMV
                     REQARVSFLNDGGLKIMNVTKADAGTYTCTAENQFGKANGTTHLVVTEPTRIILAPSN
                     MDVAVGESVILPCQVQHDPLLDIMFAWYFNGALTDFKKDGSHFEKVGGSSSGDLMIRN
                     IQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVDEITDTTAQLSWTEGTDS
                     HSPVISYAVQARTPFSVGWQSVRTVPEVIDGKTHTATVVELNPWVEYEFRIVASNKIG
                     GGEPSLPSEKVRTEEAAPEIAPSEVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAF
                     RPLGVTTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSA
                     EEEPTVAPSHISAHSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNNGGEEESSRKVK
                     VAGNQTSAVLRGLKSNLAYYTAVRAYNSAGAGPFSATVNATTKKTPPSQPPGNVVWNA
                     TDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVHVLNTNKTSAELLLPIKEDYII
                     EVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNIHPLSGYMSVLLFFIVNALW"
     exon            400..526
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            527..702
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            703..798
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            799..1002
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1105
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1290
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1427
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1557
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1708
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1836
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            1837..2012
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            2013..2130
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            2131..2289
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2439
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            2440..2510
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2745
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            2746..2861
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..3048
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            3049..3161
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            3162..3330
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     exon            3331..5445
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3582..3587
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /note="hexamer: AGTAAA"
     polyA_site      3601
                     /gene="Cntn3"
                     /gene_synonym="Pang"
     regulatory      5424..5429
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /note="hexamer: AATAAA"
     polyA_site      5445
                     /gene="Cntn3"
                     /gene_synonym="Pang"
                     /note="major polyA site"
ORIGIN      
        1 aggctgagcg gcacaggcgc aggcagcgca ccttcggcgc ctgcagcagc cacagcaacc
       61 tggcgcgcgg tggcgccggc ggcgggcggg cgggcgccgc gggtccgact gggaagtgtg
      121 cggaaccttg cagaacagcg cggacggggg cgctgcggcc aaggcggcgg ctcgcaggag
      181 cgcgcagggc agccccccgg gctagccagc ggcagcggcg ggccgggccg gcggggcggg
      241 cgccttgcaa gctggtgcag ctagattaaa ggatttactt gaagacaaat cattctattc
      301 atcagagacc agacaagagt cactcttgct tttgccaatt aaagatgatg ttgtcatgga
      361 aacagttgat cctgctttca ttcattggct gcctggcagg tgaacttctt ttacaaggcc
      421 ctgtgtttat caaagagccc agcaacagta ttttccctgt tgattcagag gacaaaaaaa
      481 taacattaaa ttgtgaagca agaggcaacc cttcacctca ttacaggtgg cagctgaatg
      541 gcagtgatat tgatacaagt ctggaccatc gttacaaact gaatggagga aatctcatag
      601 ttattaaccc taacagaaat tgggatacag gaagttacca gtgttttgca acgaattctc
      661 ttggaacaat agtgagcaga gaagccaaac tccagtttgc ctatcttgaa aattttaaga
      721 ccaggatgag aagcactgtg tcggtccgtg aaggccaggg agtggtgctt ctctgtggac
      781 ccccacctca ctcaggagaa ctgtcatatg cttgggtctt caatgagtat ccatcatttg
      841 ttgaagaaga cagtcgacga tttgtctctc aagagacagg acacctctac atagctaagg
      901 tggaaccatc tgatgtggga aattacacat gtgtggtgac cagcacggtg acaaatacca
      961 gagtattggg ctccccaacc cctttggtgc tacgctctga tggtgtcatg ggtgaatatg
     1021 aacccaaaat agaagtccag tttccagaga ctcttccagc agctaaaggt tcaactgtga
     1081 ggttggaatg cttcgccctg ggaaaccctg ttcctcagat taattggaga agaagtgatg
     1141 ggatgccgtt tcccaacaaa attaagttga ggaagttcaa tggtatgctg gaaattcaaa
     1201 acttccaaca ggaagataca ggctcctatg agtgtattgc tgaaaattca cgaggaaaaa
     1261 atgtggcgag agggcggctc acttactatg caaaacctta ttggcttcaa ctcttaagag
     1321 atgtggaaat tgctgtggag gacagtcttt attgggaatg ccgggcaagt gggaagccta
     1381 aaccctctta tcgatggctg aaaaatggag atgccttagt actagaggag agaatacaga
     1441 tagaaaatgg tgcccttaca ataaccaacc tcaatgtgac tgactctgga atgttccaat
     1501 gtatagcaga aaacaagcat ggtctcatct actccagtgc tgagctcaag gtagtagctt
     1561 ctgctccaga tttttcaaga aaccctatga aaaaaatggt ccaggtgcag gtgggcagcc
     1621 tggtgatcct ggattgtaaa cccagagcct ctccaagggc actttctttc tggaagaagg
     1681 gagacatgat ggtgcgggag caggcaaggg tttctttttt aaatgatgga ggactcaaaa
     1741 tcatgaatgt gactaaggca gacgctggaa cctacacctg cacagcagaa aaccagtttg
     1801 ggaaagcaaa tggcacaacc cacttggttg tgacagaacc tacgagaata attttggcac
     1861 cttcaaacat ggacgttgct gttggtgaga gcgtcatttt accctgccag gttcaacatg
     1921 atcccctatt agacataatg tttgcctggt atttcaatgg agcccttaca gactttaaga
     1981 aagatggatc tcactttgag aaagttggtg ggagttcatc tggtgattta atgatcagaa
     2041 acattcaatt gaaacacagt gggaagtacg tatgtatggt gcagacaggg gtggacagtg
     2101 tttcctctgc agctgagctc atcgtgagag gttcacctgg gccaccggaa aatgtgaagg
     2161 tagatgaaat tacagacaca acagcccagc tctcttggac ggaaggcacg gacagtcata
     2221 gcccagttat atcgtatgca gtccaagcta ggacgccttt ctctgtgggc tggcaaagtg
     2281 tcagaacagt acctgaggtc attgatggca agacacatac agctactgtc gtggagttaa
     2341 acccatgggt ggaatatgaa tttcgcattg tagccagtaa caaaatcgga ggtggagaac
     2401 ccagtttacc ctcagaaaaa gtaaggactg aagaggcagc tccagaaatc gcaccttctg
     2461 aggtcagcgg aggaggtgga agccgatctg aactagtgat aacctgggat ccagtccctg
     2521 aagaactaca gaatggagga ggttttgggt atgtggttgc tttccgccca cttggggtta
     2581 ccacctggat ccagacagtg gtgacatccc cagataaccc aagatacgtc tttaggaatg
     2641 aaagcattgt gcccttttcg ccatatgaag ttaaagtggg agtttacaat aacaaaggtg
     2701 aaggaccctt tagcccagtg acaactgtgt tctctgcaga ggaagagcct acagttgccc
     2761 catctcacat ctctgcccat agcctgtctt cctcagaaat tgaagtttct tggaatacaa
     2821 ttccctggaa gttgagcaat ggacatttac tgggctatga ggtgcggtac tggaacaatg
     2881 gaggagaaga agaatcatcc cgcaaagtga aagtggcagg aaatcagaca tcagctgtgc
     2941 tccgaggcct gaagagcaac ctggcctatt acacagctgt ccgggcttac aacagcgcag
     3001 gcgctggtcc cttcagcgcc acagttaatg cgaccaccaa gaaaacccct cccagtcagc
     3061 caccaggaaa tgttgtttgg aatgctacag acactaaagt gctacttaat tgggaacaag
     3121 tgaaagccat ggagaatgaa tcagaagtaa caggctacaa ggttttctat aggactagca
     3181 gtcagaataa tgtgcacgtg ctgaacacaa ataaaacttc agctgaactg ttgctgccta
     3241 tcaaagaaga ctacattatt gaggtcaagg ccaccacaga tggaggggat ggcaccagta
     3301 gtgagcagat caggattcca agaataacca gtatggatgc aagaggatcc acgtcagcca
     3361 tttctaacat ccaccctttg tcaggttata tgtctgtcct actgttcttt attgtaaatg
     3421 ctttgtggtg atagggcttt ttttttatta tttcctggaa agttaattgg ttacccccat
     3481 aaaaaaagtg ctttctgaaa cagtgattat gcatgttgtt ttcagctatg tgtttttaaa
     3541 tttctacttc attataggta aaatatgaat ctaataaaaa cagtaaatcc ttttagagga
     3601 atctgagatg ccttaatatt tgcttggtaa accaaaggaa cttgcaaatt acatactgca
     3661 aacttttgat agaaatattc ttatgttatg agtttaaaca ctttcctatg tgtgaggcac
     3721 atacacagga tgcataaaaa cacagtgcac acatgatgta tggagacaca tagtacatac
     3781 acggtacaca cagcacacac aatgcacaaa cacacacaca cacacacaca cacacacaca
     3841 cacacacaca cacacagagt ttttctatac taaaatattt ctcatttatt ccaaatgttc
     3901 ctttcccatt gttacaatat tacctatcat ttctaaatac taatttgact cctcagagga
     3961 aaatgcactt aaacagttat tctggactgg agcagcctgg aagggcgtat tgtcagaaaa
     4021 tgatactctg agcttgggga agtgacattt gcttcaatgt gctactgtat ggctgcgaga
     4081 ttccctttgt cacttcatcc tctcatcttt cacttattta ttttataaaa tgaggtgaca
     4141 atatttctcc tatcagcctt tactgcaaga atccgttgtt taaaacaaag gaagtaatgg
     4201 gaaagcattg tttcctccaa tgtgcaatgt ccctgtgcag aatcttacat gaagctacta
     4261 aggtgacaca gaacaggcac ttctttgaag cttgctggca ttgcatgctc ttcttagaat
     4321 tatccctctt cttcaaagat ggaaattgaa cctgagtgaa gattgtaaca ttgtttcttt
     4381 ttgttggtat ttacaaagaa aaagatggaa catggaaatg aatacatttt atccttcctt
     4441 aaaaattaaa gtgaacttac ttgggaaaga gaattaggac tcatcccctt cccatgtaaa
     4501 aataagcttt caggttttgt caaatcccag tagagaaaat aatgaaaaag ctgtatctta
     4561 acccaaatat aaaacaaaat gcatataatt cttcatttat aatttctgat cctattaagg
     4621 gactctctct tggtttggat ggcagagatg gatttttaat ggaattccac tctctatctc
     4681 atcgagccag gcagcctttt ccattcccaa gtaaaatttg taaaagaaca tggtgatgtt
     4741 gctggctttg atatggatga gtcgagtctt tcaatatgtg attttcaaag gactgtggaa
     4801 gacatggctt ggcagtaaca tgtagaaggt atatgaaaaa tagcagattg agtgctagaa
     4861 ttttttacca cttacctact attttcgcat tttgctggga tttttttctt attaccaaag
     4921 gtagcaaaat tggaaatcga tggtatagct ctcaagcaac attaaacctt agccaaatgc
     4981 tgataccttt ctagtgtccc acccttcttt agagattcca tttaagacaa ggttgctatg
     5041 taaaaagaag aatggggttt ttttttaagt ttttctgtag ggtctgtata tattgtacat
     5101 atcaagaaga aatccgaatg actagtggat ttcctatgac cattgttatt tccagtcaaa
     5161 atgtggggtc acactttctc caacccctgt gctttatggt acacataaca gaactatacc
     5221 ttttttattt tctgatgact ccaagaattt gttcctatag ttttctttta caagatggct
     5281 attctcttgt ttcctgttat ttctatcagt atcatctcca tgagatgtac acactgtttc
     5341 atattgaaaa gtctaaattt tactgtttaa attcctgtgt gtgtatccta tggttatctg
     5401 tatgtatgat tttctattat tctaataaaa tttataataa tcaaa
//
