LOCUS       NM_026562               2228 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus cyclin N-terminal domain containing 1 (Cntd1), mRNA.
ACCESSION   NM_026562 XM_905901
VERSION     NM_026562.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2228)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2228)
  AUTHORS   Gray,S., Santiago,E.R., Chappie,J.S. and Cohen,P.E.
  TITLE     Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover
            Formation with Cell-Cycle Progression in a Cyclin-Independent
            Manner
  JOURNAL   Cell Rep 32 (1), 107858 (2020)
   PUBMED   32640224
  REMARK    GeneRIF: Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic
            Crossover Formation with Cell-Cycle Progression in a
            Cyclin-Independent Manner.
REFERENCE   3  (bases 1 to 2228)
  AUTHORS   Bondarieva,A., Raveendran,K., Telychko,V., Rao,H.B.D.P.,
            Ravindranathan,R., Zorzompokou,C., Finsterbusch,F., Dereli,I.,
            Papanikos,F., Trankner,D., Schleiffer,A., Fei,J.F., Klimova,A.,
            Ito,M., Kulkarni,D.S., Roeder,I., Hunter,N. and Toth,A.
  TITLE     Proline-rich protein PRR19 functions with cyclin-like CNTD1 to
            promote meiotic crossing over in mouse
  JOURNAL   Nat Commun 11 (1), 3101 (2020)
   PUBMED   32555348
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2228)
  AUTHORS   Holloway,J.K., Sun,X., Yokoo,R., Villeneuve,A.M. and Cohen,P.E.
  TITLE     Mammalian CNTD1 is critical for meiotic crossover maturation and
            deselection of excess precrossover sites
  JOURNAL   J Cell Biol 205 (5), 633-641 (2014)
   PUBMED   24891606
  REMARK    GeneRIF: CNTD1 has a critical role in meiotic crossover maturation
            and deselection of excess precrossover sites
REFERENCE   5  (bases 1 to 2228)
  AUTHORS   Yue,Z., Horton,A., Bravin,M., DeJager,P.L., Selimi,F. and Heintz,N.
  TITLE     A novel protein complex linking the delta 2 glutamate receptor and
            autophagy: implications for neurodegeneration in lurcher mice
  JOURNAL   Neuron 35 (5), 921-933 (2002)
   PUBMED   12372286
REFERENCE   6  (bases 1 to 2228)
  AUTHORS   Liang,X.H., Kleeman,L.K., Jiang,H.H., Gordon,G., Goldman,J.E.,
            Berry,G., Herman,B. and Levine,B.
  TITLE     Protection against fatal Sindbis virus encephalitis by beclin, a
            novel Bcl-2-interacting protein
  JOURNAL   J Virol 72 (11), 8586-8596 (1998)
   PUBMED   9765397
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK007245.1.
            
            On Apr 6, 2007 this sequence version replaced NM_026562.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK007245.1, BC006866.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2228              AK007245.1         2-2229
FEATURES             Location/Qualifiers
     source          1..2228
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 64.56 cM"
     gene            1..2228
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /note="cyclin N-terminal domain containing 1"
                     /db_xref="GeneID:68107"
                     /db_xref="MGI:MGI:1923965"
     exon            1..278
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..1108
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /codon_start=1
                     /product="cyclin N-terminal domain-containing protein 1"
                     /protein_id="NP_080838.1"
                     /db_xref="CCDS:CCDS25461.1"
                     /db_xref="GeneID:68107"
                     /db_xref="MGI:MGI:1923965"
                     /translation="MNMEGPLRPRLVNCSDFQFGVVTTETIENALLHLAQQNEQAVKE
                     AAGRTGSFRETRIVEFVFLLSEQWCLEKSVSYQAVEILERFMLKQAEDICRQATLQLR
                     GKDTELQSWRAMKEQLVNKFILRLVSCVQLASKLSFHYKIVSNITVLNFLQALGYVHT
                     KEELLESELDILKSLNFQINLPTPLAYVEMLLEVLGYNGCLVPATQLHATCLTLLDLV
                     YLLHEPIYESLLRASIENSTPSQLQGEKFLSVKEDFMLLAVGIIAASAFIQNHECWSQ
                     VIGHLQSITGIASESIAEFSYAILTHSVGANTPGPQQPVPHKAARALRTAAAAASSNT
                     "
     exon            279..354
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /inference="alignment:Splign:2.1.0"
     exon            355..526
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /inference="alignment:Splign:2.1.0"
     exon            527..689
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /inference="alignment:Splign:2.1.0"
     exon            690..834
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /inference="alignment:Splign:2.1.0"
     exon            835..931
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /inference="alignment:Splign:2.1.0"
     exon            932..2228
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2228
                     /gene="Cntd1"
                     /gene_synonym="1700051C09Rik; 4921513J16Rik;
                     5430417M23Rik; Cntd"
                     /note="putative"
ORIGIN      
        1 agaaagggaa ggaagaatcc aaggtgtggc agaagattct ggaaataagc taaggaggcc
       61 agtttatgga tcccgtaaac tgtccaagta ctccgaaaga cttatgaata tggaaggacc
      121 cttgaggccc aggctggtga actgtagtga ctttcagttc ggagtggtta ccacagagac
      181 tatcgaaaac gccctgcttc acttggccca gcagaacgag caagccgtga aggaggctgc
      241 gggacggacg ggcagcttca gggagacccg gatcgtggag tttgtttttc tcctgtctga
      301 acaatggtgt ctggagaaat cggtgagcta ccaggctgta gaaatcctag aaagattcat
      361 gctgaagcag gcagaggaca tctgtcggca agccacactc cagctgagag gtaaagacac
      421 agagctgcag agctggaggg ctatgaaaga gcagcttgtc aacaagttca tcctccgatt
      481 ggtgtcgtgt gttcagctgg ccagcaaact gtctttccac tacaaaattg tcagcaacat
      541 tacagtcctg aatttcctcc aggctctggg ttatgtacac accaaagaag aactgctgga
      601 gtcagagctc gatattttga agtccctgaa cttccaaata aatctgccca ctcctctggc
      661 atatgtggag atgctccttg aagtcctagg gtacaatggc tgtttggtcc ctgccacaca
      721 actacatgca acttgtctga ccctcctcga cctggtctat cttctgcatg aacccatcta
      781 tgagagccta ttgagagctt caattgagaa ttctacaccc agtcagctgc agggggaaaa
      841 gtttctctct gtgaaggaag actttatgct cttggcagtt ggaatcattg cggcgagtgc
      901 cttcatccaa aaccatgaat gctggagcca ggttataggg cacttgcaga gcatcactgg
      961 cattgcctcg gaaagcattg ctgagttctc ttacgcaatc ctgactcaca gcgtgggagc
     1021 aaacactcct gggccacagc agcctgttcc ccacaaggca gccagagctc tgaggactgc
     1081 tgccgctgcc gcttcctcta acacgtgagg gtggctgacc cgcactgcct tgtcactgga
     1141 cctctttcct tgtttacttt tatactcagg gtacaaaaaa ttccaaattt cctttgaaca
     1201 gtgttttgta ttccagtttc aggcatgtta tttttttcta catcagagat agttatggga
     1261 gacaaacata tctgttgtgt catggtaggc taaaaaaaac atcaaagaat tggactgagt
     1321 tgatgatgaa actagttcat ttttgtttga taatactttt aatttttcct aagttaatct
     1381 aactaagagg taatatcaga tagagataag tattttgggg gactttagag cattttcgat
     1441 gaccttgact gaatctcttt gaagtaacct ttctttcctt gctcccccta cagctggttg
     1501 ttttgttctg ttttgttttg ttttgttttg ttttattttg ttaagacagg gtctcaatac
     1561 tcagccctgg ctgccttgca actcactata cacaccaggc tgggctgaaa ttcagagggt
     1621 cacttgcctc tctctgcctc tcagtgctgg ggctaaatac catcatttgt ttttctcttt
     1681 aaactaagac atgtttcaac agaatttcta ctgaactgac tacaactcaa ttctttcaga
     1741 atacaaaata ctcaatttta aggaaaaaca tacaggcgta ccacttggta attaatagac
     1801 catagcaaat cctttattac aaataattaa atctctccac gtcgcacaca gtatcaaaca
     1861 gcattctgta gtcccactag acagcacagg aggcattcaa tgctacaagt gaggacggag
     1921 ttaaacttgc aactcctgac ccggtgtcct ttccccacat cacccaactg tgtgccacaa
     1981 gcatctcatc tcaaaccttt gctgtttcaa attttaagtg caggaagttg agagagataa
     2041 aatccagtga aaacacatta acgtcaattc aacttaaaaa agaaaacaaa gcaaatttaa
     2101 attagttgtt ttcaggaaag agggaaagga tgcatggggc tgagtcaaaa ctatggcagg
     2161 gttctttgct atacatggcg tactctggaa actatctgtc atatttgaaa ataaagtagc
     2221 ttttgtgg
//
