LOCUS       NM_001285511            8696 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus CCR4-NOT transcription complex, subunit 6-like
            (Cnot6l), transcript variant 3, mRNA.
ACCESSION   NM_001285511
VERSION     NM_001285511.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8696)
  AUTHORS   Zhang,Y., Liu,G., Ding,H. and Fan,B.
  TITLE     High expression of CNOT6L contributes to the negative development
            of type 2 diabetes
  JOURNAL   Sci Rep 14 (1), 24723 (2024)
   PUBMED   39433858
  REMARK    GeneRIF: High expression of CNOT6L contributes to the negative
            development of type 2 diabetes.
            Erratum:[Sci Rep. 2024 Dec 23;14(1):30627. doi:
            10.1038/s41598-024-83685-w.. PMID: 39715822]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8696)
  AUTHORS   Jiang,X., Cheng,Y., Zhu,Y., Xu,C., Li,Q., Xing,X., Li,W., Zou,J.,
            Meng,L., Azhar,M., Cao,Y., Tong,X., Qin,W., Zhu,X. and Bao,J.
  TITLE     Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression
            and maturation in mice
  JOURNAL   Nat Commun 14 (1), 3729 (2023)
   PUBMED   37349316
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8696)
  AUTHORS   Qian,B., Li,Y., Yan,R., Han,S., Bu,Z., Gong,J., Zheng,B., Yuan,Z.,
            Ren,S., He,Q., Zhang,J., Xu,C., Wang,R., Sun,Z., Lin,M., Zhou,J.
            and Ye,L.
  TITLE     RNA binding protein RBM46 regulates mitotic-to-meiotic transition
            in spermatogenesis
  JOURNAL   Sci Adv 8 (34), eabq2945 (2022)
   PUBMED   36001654
REFERENCE   4  (bases 1 to 8696)
  AUTHORS   Quan,Y., Wang,M., Xu,C., Wang,X., Wu,Y., Qin,D., Lin,Y., Lu,X.,
            Lu,F. and Li,L.
  TITLE     Cnot8 eliminates naive regulation networks and is essential for
            naive-to-formative pluripotency transition
  JOURNAL   Nucleic Acids Res 50 (8), 4414-4435 (2022)
   PUBMED   35390160
REFERENCE   5  (bases 1 to 8696)
  AUTHORS   Katsumura,S., Siddiqui,N., Goldsmith,M.R., Cheah,J.H., Fujikawa,T.,
            Minegishi,G., Yamagata,A., Yabuki,Y., Kobayashi,K., Shirouzu,M.,
            Inagaki,T., Huang,T.H., Musi,N., Topisirovic,I., Larsson,O. and
            Morita,M.
  TITLE     Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates
            food intake and energy expenditure
  JOURNAL   Cell Metab 34 (4), 564-580 (2022)
   PUBMED   35385705
  REMARK    GeneRIF: Deadenylase-dependent mRNA decay of GDF15 and FGF21
            orchestrates food intake and energy expenditure.
REFERENCE   6  (bases 1 to 8696)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   7  (bases 1 to 8696)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   8  (bases 1 to 8696)
  AUTHORS   Morita,M., Suzuki,T., Nakamura,T., Yokoyama,K., Miyasaka,T. and
            Yamamoto,T.
  TITLE     Depletion of mammalian CCR4b deadenylase triggers elevation of the
            p27Kip1 mRNA level and impairs cell growth
  JOURNAL   Mol Cell Biol 27 (13), 4980-4990 (2007)
   PUBMED   17452450
  REMARK    GeneRIF: CCR4b may be involved in various cellular events that
            include cell proliferation.
REFERENCE   9  (bases 1 to 8696)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   10 (bases 1 to 8696)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK151728.1, AK030112.1 and AC129600.4.
            
            Transcript Variant: This variant (3) differs in the 5' UTR and the
            5' coding region and initiates translation at a downstream start
            codon, compared to variant 2. Variants 1 and 3 encode the same
            isoform (1), which is shorter and has a distinct N-terminus,
            compared to isoform 2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13948564.3185823.1,
                                           SRR7345562.1391479.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-892               AK151728.1         4-895
            893-2020            AK030112.1         769-1896
            2021-2228           AK151728.1         1885-2092
            2229-8696           AC129600.4         179744-186211       c
FEATURES             Location/Qualifiers
     source          1..8696
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 47.29 cM"
     gene            1..8696
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /note="CCR4-NOT transcription complex, subunit 6-like"
                     /db_xref="GeneID:231464"
                     /db_xref="MGI:MGI:2443154"
     exon            1..186
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            187..308
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..1849
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /EC_number="3.1.13.4"
                     /note="isoform 1 is encoded by transcript variant 3"
                     /codon_start=1
                     /product="CCR4-NOT transcription complex subunit 6-like
                     isoform 1"
                     /protein_id="NP_001272440.1"
                     /db_xref="CCDS:CCDS19448.1"
                     /db_xref="GeneID:231464"
                     /db_xref="MGI:MGI:2443154"
                     /translation="MPKEKYDPPDPRRIYTIMSAEEVANGKKSHWAELEISGRVRSLS
                     TSLWSLTHLTALHLNDNNLARIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLREL
                     LLNDNYLRVLPYELGRLFQLQTLGLTGNPLSQDIMSLYQDPDGTRKLLNFMLDNLAVH
                     PEQLPPRPWITLKERDQILPSASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKG
                     IMEEIVNWDADIISLQEVETEQYFTLFLPALKDRGYDGFFSPKSRAKIMSEQERKHVD
                     GCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAMLNRVMTKDNIGVAVVLEVHKELF
                     GTGMKPIHAADKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASSRPGSPT
                     ADPNSIPLVLCADLNSLPDSGVVEYLSNGGVADNHKDFKELRYNECLMNFSCSGKNGS
                     SEGRITHGFQLKSAYENNLMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLV
                     ENNITGCPHPHIPSDHFSLLTQLELHPPLLPLVNGVHLPNRR"
     exon            309..495
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            496..581
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            582..671
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            672..740
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            741..898
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1053
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1205
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1206..1433
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1636
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..8696
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5712..5717
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      5751
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /note="major polyA site"
     regulatory      6202..6207
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /note="hexamer: CATAAA"
     polyA_site      6240
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
     regulatory      8672..8677
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /note="hexamer: AATAAA"
     polyA_site      8696
                     /gene="Cnot6l"
                     /gene_synonym="4932442K20Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtgggtgtgc gtgtgtgtcg cgtgtgtgtg tgtctgcgtg tgtgtgtgtc gggcggcggg
       61 agccggcccg cgtcgcctca gggggcgcgg gttccaggcc gtgtgcgtgt ggggaggggg
      121 acggagtcgg ggaccccaga gcgtcgaggt ccttccgctt cgaggccggg gctcagagcc
      181 tcacagacta atagggatgc caaaggaaaa atatgatcct ccagatcctc gcagaattta
      241 caccatcatg tccgcagagg aggtagccaa tgggaaaaaa tctcactggg cagagttaga
      301 gatctcgggt agagtgcgga gcttaagtac atcactctgg tcattaacac acttgacagc
      361 actgcaccta aatgacaata accttgctcg cattccacct gatattgcca agcttcataa
      421 tctggtttac ctggatctgt catccaataa actcagaagt ttaccagcag aactaggaaa
      481 catggtgtct ctcagggaat tgcttttaaa tgacaattat ttacgggtgt tgccttatga
      541 acttggccgg ctcttccagc tacaaactct aggtttaaca ggcaatcctt tatcacagga
      601 tattatgagc ttataccagg acccagatgg aacccgaaag ctactgaact tcatgcttga
      661 caatcttgca gttcatccag agcagcttcc tccgaggcca tggattacat taaaagaacg
      721 agaccaaatt ctgccatcag catcattcac ggttatgtgt tacaatgtgt tatgtgataa
      781 atatgctacc aggcagctat atggctattg tccgtcctgg gcattaaact gggaatacag
      841 gaaaaaggga attatggaag aaattgttaa ctgggacgca gatatcatta gtcttcagga
      901 agtggaaaca gagcaatact ttactctctt tctgccagca ttgaaggatc gtggatatga
      961 tggatttttt tctccaaagt cacgtgccaa aatcatgtct gagcaggaaa gaaagcatgt
     1021 ggatggttgt gcaatattct tcaaaacaga aaaatttaca ttggtgcaga agcatacagt
     1081 ggaattcaac caggtagcaa tggcaaattc agatggatcc gaagcaatgc taaacagagt
     1141 aatgacgaaa gataacattg gcgttgctgt ggtgttagag gtccacaagg agctttttgg
     1201 aacaggtatg aagcctattc atgctgcaga caaacagctg cttatagtgg caaatgccca
     1261 catgcattgg gacccagagt attctgatgt gaaacttatt cagaccatga tgtttgtctc
     1321 agaggttaaa aacattctgg agaaagcctc aagtaggcct ggcagcccaa ctgcagatcc
     1381 caattccatc ccgctggtgc tatgtgcaga tcttaactca ttgccagatt caggtgttgt
     1441 ggaatattta agcaacggtg gagtagctga caaccataaa gacttcaagg aactaaggta
     1501 caatgagtgt cttatgaact tcagctgtag tggaaagaat ggaagctcag aagggagaat
     1561 cacacatggc ttccaactta agagcgccta tgaaaataac ttgatgcctt ataccaatta
     1621 cacctttgat ttcaaaggtg tgattgacta cattttctat tccaagactc atatgaacgt
     1681 gcttggtgtc ctggggcctt tagatcctca atggctggtt gagaacaaca tcactgggtg
     1741 tccacaccct cacatccctt cagaccactt ctcactgtta acacaacttg aactccaccc
     1801 tccactcctg cctcttgtca atggtgttca cttgcctaat cggaggtagt ggagtacagc
     1861 cccgcagaga cggggatctg tcgctatgga cctgtacagt tgtaaatcaa agtatgtagg
     1921 agtgaagtat ggccatcttt aacgctgctt cttcaggttc ctttcactat gtgtttgcta
     1981 taagactgta tatttttgtg catactgata tcatttggca ctagggctgg aaccaaagta
     2041 ttgctgtctg tctctatcca aaagtttaat acactttaaa attggattta ttttcctatt
     2101 atattaggaa ccaacattca cgattgataa atcactaatt tgagacccca caccattgtt
     2161 gttctctaaa aacaaataca ttcttttgaa tgttttcaaa taagccaatc atttttgtaa
     2221 aaggtgattt aaaaaaaaaa aaaaaactcc aaatacaaga ttttcaattg aatgatggta
     2281 tgccttatag gaaaaacttt gagtttctgt tttctttcat aacaagctga tttttggctc
     2341 tcaagtcatt tgcacattat caaagcactt aaatttgctt gatttgtaca ttaaatttga
     2401 tatagccact agctataaca agacaattcg ggaaatgaaa gacaattgca taacatgctt
     2461 taaaatcaag catagtatgt gacagtttgt tggccaaatg ctggttgttt tgtttgagga
     2521 atcttttctc ttctcttctt ttttcctttt ccttttccct ttctcttttc tcttttttct
     2581 tttcttgtct gcctgttagt cctaatctct ttagaagtat taactttaag cccatctctc
     2641 aagttcattt ataaggaaat agcagataat actgccatat atcttgaaag taaaatttgg
     2701 tatttttagg atgcccacaa aattagtgtc tggtattttt cattttcgtg cccaaacttt
     2761 tattttctgt ccggttgtac tggaaaaata tgatctatat ctttaccact acagtttaac
     2821 acttaaggaa aattgctgaa tgaaaagccc ctggtcagtt tcagaaaggg caagccagat
     2881 aatattatac gtgttttcca aagtaagtaa aatggctgtt tgtttgttgt tttggttttt
     2941 tttgtttcat tttaaggtaa cagtagagat gatttagagg aaaggacaga tttggggaca
     3001 taattgaaaa ccttggatca cttttttctg actctagctg ccaaatggcc atcatatgct
     3061 tttaatcttc gttgccatac tgtctagatt tgaattaagc tactgtttta ttcccaaagt
     3121 ttgatgcctc tatatgtatt gggaaacacc accaccacca ccatttattg ttggccagga
     3181 ggtgccactt gagaatctta cgtaagaggc agagagcata aacaccattt gtggggagaa
     3241 aattagttgg caaaattaga aaatgttaat tatggcacag taacattgga aaaggttgtg
     3301 tctgtgtttt taagtttttc tttattctgc ttttttgctg ctataagagt tttctgaaat
     3361 ttatattgta aacttttcat gcactttact gtttctagta tcaaaatgtg atatttttaa
     3421 taaacaagaa attttccatt atgtgatgaa atttaaaaag aaaataacct atatttgtgt
     3481 ctcactaata tataaagtac aagtcaaatt taaattattt aattagcttt aaatatatac
     3541 aaattgtctc ctcttccaaa cctgacctct taggctgttt tattagtctt aaatgataca
     3601 tttcctgtgg tcattttata ctaatttctt ccatagttta ctgatcaggc tatataaaag
     3661 aatatttccc gaagggtaat tttagtggga tgagggtggt ggggtgatgt aatatcacgc
     3721 aggattgcat ccagaagagc tctgtaaagc ctaaactccc tttaaaaagt gcctagtgac
     3781 agaggcgttg tcatctattg taattggaat gtcattgtag ttcagcaaag tttgatgtaa
     3841 ataaaatatt cttttaaaaa tgttaaagta cctgaataaa caaacaaaag aaacccttga
     3901 tgacagattt tcctcagtgt tcaggtatcc cttcttatat acctcaagca tccaacatct
     3961 agccatgaag attgattacc tgacgcatag tactggaaag tagaatagca tgaaaaactt
     4021 aactgtgtgg acattacctt tttctgtaat cagctactgt ctgtttagtt ttctcctgtt
     4081 tcgggtgggc tttcttctct ggaggtatgt gcactaacag aacatccttc tttttttcat
     4141 agatgcatgt taactagcaa tgtgagcaat atttcctacc atacttcact cccaatattt
     4201 ttgagatgtt tgtataaaat gaaatttaaa gttcacttat gattgtatat gaaccacaga
     4261 ggagcccatt tattaataca aatctttttt aatagttaaa tgtagagggg gaaaataaaa
     4321 aaatgggaaa cattgtaaac agcttaagtt tattttgtgt atgatcgagg cactctgttg
     4381 caagaaggtg tgtaattggg tctctctgct tccaaatgca ctctttcaaa ccattcatta
     4441 tcctgtgtat tttaatgtgg ttttcgtaaa tgttggtagt agctctgttg aagtaggtga
     4501 ttgtgttttg ttttgggtgg cacacaccta gggcatggta tcccaaattt catgtgcacg
     4561 gtttcccttt agcctcttgc ccaaatttaa cacactgttt cccctcgttc cctttgtaaa
     4621 aggagtggta tcttgttttg agctgccagt tcagatgatc agaaatgctg ctgtcctcag
     4681 cattgtcttg ttaaatgcat gccatttgga actttggcag tgagaagccc aaaggacaag
     4741 gtgaatgacg tgatatatat tcgataaaag tgaaatatat atactcatat actttctagt
     4801 tctcagaata agttaataag ctttatgcct ttgggctgct gcatatttta tctgataaga
     4861 gaaaatttgg gcatttttag attgtgctat gtattttttt aaatgttcaa tatgatttct
     4921 ggtaattgtc ttaagaactg gagtgttaag tttattaaaa tggtgttgtt tgaagaaggg
     4981 gaaactgcac tgtttgccat tataaaagta atacaagtgc atgtcccgtc acccactgtc
     5041 aggcatcagt atcctcatag ctttacacac tctgatgggg aatattgcag cattctcagg
     5101 actgacatct ggaaaaggct caaatcactt actgctcctt gcttgttgac tttgttttac
     5161 aatattgtgc ctggtgtcaa cttttaagca acagcactgc ctaaaagcaa gcagagaaca
     5221 gaatcccagc accattctat aggcaacttt ttagaattca gatacagtaa atctgttcaa
     5281 gatttatgat gttttatgta aaaaaaattt tgtactacat agctgaatat ttttgtttga
     5341 tttatttgat gtaaggcgtg tgaacattca tttgaatatc acatgttaaa gtcaggtatg
     5401 gcacaatggg ctctgagacc agcttccccc cgcacccccc ccccatttgc cttgttctaa
     5461 tctctttctt ttcaaattgc atttctggta ttcataagca gatatttaat tttactaata
     5521 agcatcctgt gtgaatgtac tttaaaagcc actatgtttt agtgttatgg tttgtagaat
     5581 tatgaaactt accttctccc cctccttttt ttgtcttaaa gtcataaatc tctgagaagg
     5641 gagaaagtta aaatccaaga ctcatatcac ttgaatctgt ggcagattat gttaaaattg
     5701 agggtgtggc aattaaacct agaacatgga caatattgtg ctgtttaaaa attctgtctc
     5761 ctgagtatgt cttgtcaata ggtgaaattt taagtctgta ttgtacttcc aagaattagt
     5821 aaaactcgca aataccacct gtatactcaa tagcgaatag caaagggaag gggagcacac
     5881 aggagtggta ggtcaggtat gcgcctggaa ggggttagag agcgccatct ctaacacagg
     5941 ctacattccc cagtggtaaa atttgatgtt ggcttaatac cgatttaaaa tttcatcttt
     6001 tatattcttg tgttttttga aatattttaa tagttttgca aagtatacta actggttcgt
     6061 agcttcagtc acagaaaaca aattgtattt cagtaatggt cctgtagcaa gcaagaattc
     6121 tttgttacat gttctaagta acaaacattt tgactgaaaa gtgagctgtt gtgtttgtaa
     6181 ggttttcttc ttctctccac ccataaaacc caaagtaaca cctttctaat gtgttaaaaa
     6241 tttgtttacc gacttttatt tggtttgtat cctatttgta tgacttttgc gtattagaag
     6301 tagatagatt aggtagagac attagactta tttttctaaa tcaggaactt aaactgaagt
     6361 tttgaatttg tagacagagg acatttatgc ttatgattgt tctggaagat tttaatttct
     6421 gtaaatgcac catgatcccc aaatttaaaa ttcaaacaca agtaaatgat agtacatctt
     6481 taacctgctt atttaccaaa gtttaagaat agggtgccaa gagcatcttt cataattgtc
     6541 acctgaatgc ttaaaacgat aaaagaaaac ccttatgtgt tctgagcaag agccacagaa
     6601 agaaaactag gaagggaagc agaagggtgg gagcctgctc aggaagagga tacggaagag
     6661 catgtatgct tgttctgacc aaaggcattc gtgtcgacgt ctcaggtaaa aggcctggag
     6721 gaagaagcag attccagggg aagttttatt aacccagtaa ttttggcata agtttggtta
     6781 acttgattta ttctagattt gatttacttt tggatccaaa ggacagactg aaagtactct
     6841 ttatttagta agataagcta attttcaaag gatatgaatt aagggcgtgc ctattaaatg
     6901 ttgactttta tggtgcagcc tataaaacag atagcactga actgaaatta gaagtgtgcc
     6961 atcagaagcc atgacgcctg gagcggtggc atgatgcacc tttcaggatg acatgtgttc
     7021 ctggttattt tcttcagcgg gatccctgca tttgtttgtt ttccgtttat ctgtcccttg
     7081 gaaaatcatg gtagcatccc tctggaaggt gacccttgct cacgatttca gaggactcac
     7141 atattttctt agctattatt gttctgtgta ccacgttgtt taatttgtgt gtgtagttac
     7201 ttgaactcag actataggct caatactggt gtgccaaaca atggctctgc ttcttatggt
     7261 acagacttag tgtcctgctt actgtttcaa ctttaatgcg gtaagtgttg cagtgtgtgg
     7321 gttgctcttt attcagaaac tactgtcctt tctctgtgct taacttgcta aaagtaaatt
     7381 cccttacctg tgtaattcct gagcggtgct ctgctgacct ttgagagagg aggggtttgg
     7441 atggctgtta ctacacactg gatctggaat tgttcagtgt tgtgagtggc agatttctta
     7501 aacaccagca gcactgagaa gtgcactacg ggcatttgta aagttagttg tccaaatgca
     7561 agcagtactt tcatccaaaa gaagctgagg tgtgttgggt tcaataggag tactttgagt
     7621 atctcaagga ggacaaatga ttaactctgt tgtatctgaa gtggggtagc cctttctcca
     7681 ccccccttgt gtttttgttt tctaaagata aaatataccc ttttgctttc tttgaaaagg
     7741 ccaggatgtt tgattatatt gaccagagat taaatcgtat ctagttttca actatataag
     7801 tgccaagtaa ttgtccatgg actttttaac catttgatta gggaagagat tatttatttt
     7861 tgtttcctgg cattaagatg attaatttat tgttttgcgt acacttgagt cattctgtgg
     7921 cctatatagt gtttttgtaa ctaactatac aaaaagcaaa gcacatgacc ctaagactaa
     7981 gcaagatgtt tcagtagttc tctccgtgaa tacttgatca tttctattaa tactgttcta
     8041 agcagattct actgttttag gttgtgtatt tatttttccc cctaagaaaa agccaagcac
     8101 taaatcaact tgtgttctga taatcactta caatcttaag ctttcctttc ttcttttctt
     8161 aggtgattta atgaagtgcc atgtaattgt agcttactaa ttaatgtttg atagactggt
     8221 tctgtgatat tctaaacatt taactctttc ttgtcatctc tggagaagat ggttctattc
     8281 tcattctctc tgataaaatc accagctgct ttatttttct atttattaca cagttgataa
     8341 ggtctggatc ttgaccgaac tgctcagctg agatgttttc atagtggaca ctatagaaaa
     8401 tgtgtgtgca aaacgacaca gttgggtggt ggtattcttt ttcattaatg tgaacattga
     8461 ctaaacaaag cagtcctgcc ttttaaatct tgtggcagct cagaagggag gtgcttaaga
     8521 accttaacta ttatgtcaga tgacaaatac tttttttcca ttttggagat tgggtactgc
     8581 tcacacatga tgtatagggc taaatatatg cttgtttcct tgcacctgtg tactcttccc
     8641 cttctctccc acttttcctt tccctgtagg caataaatgg ccattttgca accgca
//
